The role of MAP kinase phosphatase-1 in the protective mechanism of dexamethasone against endotoxemia

Life Sciences

Volumn 83, Issue 19-20, 2008, Pages 671-680

  Wang, Xianxi ^a,b   Nelin, Leif D ^a,b   Kuhlman, Joshua R ^a,b   Meng, Xiaomei ^a,b   Welty, Stephen E ^a,b   Liu, Yusen ^a,b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Anti inflammatory; Cytokines; Glucocorticoids; Mkp 1; Phosphatase; Septic shock

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; DEXAMETHASONE; GLUCOCORTICOID; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG MECHANISM; ENDOTOXEMIA; ENZYME ACTIVATION; IMMUNE RESPONSE; KNOCKOUT MOUSE; MORTALITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; SEPTIC SHOCK; WILD TYPE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CYTOKINES; DEXAMETHASONE; DUAL SPECIFICITY PHOSPHATASE 1; ENDOTOXEMIA; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; SPLEEN;

MUS;

EID: 54949096502     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2008.09.003     Document Type: Article

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