Sorting an LDL receptor with bound PCSK9 to intracellular degradation

Atherosclerosis

Volumn 237, Issue 1, 2014, Pages 76-81

  Leren, Trond P ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Cathepsin; Degradation; Endosome; LDL receptor; PCSK9

Indexed keywords

EPIDERMAL GROWTH FACTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; SERINE PROTEINASE; UNCLASSIFIED DRUG; CATHEPSIN; CYSTEINE; LIGAND; PCSK9 PROTEIN, HUMAN;

CARBOXY TERMINAL SEQUENCE; CELL DIVISION; CELL SURFACE; CONFORMATION; CONFORMATIONAL TRANSITION; CYTOPLASM; DEGRADATION; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HEPG2 CELL LINE; INTRACELLULAR DEGRADATION; LIGAND BINDING; LYSOSOME; MOLECULAR WEIGHT; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; STATIC ELECTRICITY; STOICHIOMETRY; UBIQUITINATION; ANIMAL; BLOOD; CELL MEMBRANE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PH; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

ANIMALS; CATHEPSINS; CELL MEMBRANE; CYSTEINE; ENDOSOMES; HUMANS; HYDROGEN-ION CONCENTRATION; LIGANDS; LYSOSOMES; PROPROTEIN CONVERTASES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, LDL; SERINE ENDOPEPTIDASES;

EID: 84907685052     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2014.08.038     Document Type: Review

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