PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment

Journal of Lipid Research

Volumn 54, Issue 6, 2013, Pages 1560-1566

  Tveten, Kristian ^a   Strmø, Thea Bismo ^a   Berge, Knut Erik ^a   Leren, Trond P ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Cathepsin; Cleavage; Degradation; Endosome; Low density lipoprotein

Indexed keywords

GAMMA SECRETASE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EMBRYO; ENDOSOME; HUMAN; HUMAN CELL; INTERNALIZATION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

CATHEPSIN; CLEAVAGE; DEGRADATION; ENDOSOME; LOW DENSITY LIPOPROTEIN;

AMYLOID PRECURSOR PROTEIN SECRETASES; HEP G2 CELLS; HUMANS; LIPOPROTEINS, LDL; MUTATION; PROPROTEIN CONVERTASES; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RECEPTORS, LDL; SERINE ENDOPEPTIDASES;

EID: 84877887070     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M034371     Document Type: Article

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