-
1
-
-
84897556468
-
Adult tissue sources for new β cells
-
Nichols RJ, New C, Annes JP. Adult tissue sources for new β cells. Transl Res. 2013;163(4):418–431.
-
(2013)
Transl Res
, vol.163
, Issue.4
, pp. 418-431
-
-
Nichols, R.J.1
New, C.2
Annes, J.P.3
-
2
-
-
0015381073
-
Effects of pregnancy in the rat on the size and insulin secretory response of the islets of Langerhans
-
Green IC, Taylor KW. Effects of pregnancy in the rat on the size and insulin secretory response of the islets of Langerhans. J Endocrinol. 1972;54(2):317–325.
-
(1972)
J Endocrinol
, vol.54
, Issue.2
, pp. 317-325
-
-
Green, I.C.1
Taylor, K.W.2
-
3
-
-
0018182423
-
A morphological study of the endocrine pancreas in human pregnancy
-
Van Assche FA, Aerts L, De Prins F. A morphological study of the endocrine pancreas in human pregnancy. Br J Obstet Gynaecol. 1978;85(11):818–820.
-
(1978)
Br J Obstet Gynaecol
, vol.85
, Issue.11
, pp. 818-820
-
-
Van Assche, F.A.1
Aerts, L.2
De Prins, F.3
-
4
-
-
0030825432
-
Adaptation of islets of Langerhans to pregnancy: Beta-cell growth, enhanced insulin secretion and the role of lactogenic hormones
-
Sorenson RL, Brelje TC. Adaptation of islets of Langerhans to pregnancy: beta-cell growth, enhanced insulin secretion and the role of lactogenic hormones. Horm Metab Res. 1997;29(6):301–307.
-
(1997)
Horm Metab Res
, vol.29
, Issue.6
, pp. 301-307
-
-
Sorenson, R.L.1
Brelje, T.C.2
-
5
-
-
53549093011
-
Pancreatic beta-cell mass in European subjects with type 2 diabetes
-
Rahier J, Guiot Y, Goebbels RM, Sempoux C, Henquin JC. Pancreatic beta-cell mass in European subjects with type 2 diabetes. Diabet Obes Metab. 2008;10(Suppl 4):32– 42.
-
(2008)
Diabet Obes Metab
, vol.10
, pp. 32-42
-
-
Rahier, J.1
Guiot, Y.2
Goebbels, R.M.3
Sempoux, C.4
Henquin, J.C.5
-
6
-
-
33744979065
-
Relationship between beta-cell mass and fasting blood glucose concentration in humans
-
Ritzel RA, Butler AE, Rizza RA, Veldhuis JD, Butler PC. Relationship between beta-cell mass and fasting blood glucose concentration in humans. Diabetes Care. 2006;29(3):717–718.
-
(2006)
Diabetes Care
, vol.29
, Issue.3
, pp. 717-718
-
-
Ritzel, R.A.1
Butler, A.E.2
Rizza, R.A.3
Veldhuis, J.D.4
Butler, P.C.5
-
7
-
-
2342510386
-
Adult pancreatic betacells are formed by self-duplication rather than stem-cell differentiation
-
Dor Y, Brown J, Martinez OI, Melton DA. Adult pancreatic betacells are formed by self-duplication rather than stem-cell differentiation. Nature. 2004;429(6987):41–46.
-
(2004)
Nature
, vol.429
, Issue.6987
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
8
-
-
9644266753
-
Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass
-
Georgia S, Bhushan A. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. J Clin Invest. 2004; 114(7):963–968.
-
(2004)
J Clin Invest
, vol.114
, Issue.7
, pp. 963-968
-
-
Georgia, S.1
Bhushan, A.2
-
9
-
-
34247644369
-
Growth and regeneration of adult beta cells does not involve specialized progenitors
-
Teta M, Rankin MM, Long SY, Stein GM, Kushner JA. Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev Cell. 2007;12(5):817–826.
-
(2007)
Dev Cell
, vol.12
, Issue.5
, pp. 817-826
-
-
Teta, M.1
Rankin, M.M.2
Long, S.Y.3
Stein, G.M.4
Kushner, J.A.5
-
10
-
-
44749088201
-
Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans
-
Meier JJ, Butler AE, Saisho Y, et al. Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans. Diabetes. 2008;57(6):1584–1594.
-
(2008)
Diabetes
, vol.57
, Issue.6
, pp. 1584-1594
-
-
Meier, J.J.1
Butler, A.E.2
Saisho, Y.3
-
11
-
-
84872035827
-
β-Cell mass and turnover in humans: Effects of obesity and aging
-
Saisho Y, Butler AE, Manesso E, Elashoff D, Rizza RA, Butler PC. β-Cell mass and turnover in humans: effects of obesity and aging. Diabetes Care. 2013;36(1):111–117.
-
(2013)
Diabetes Care
, vol.36
, Issue.1
, pp. 111-117
-
-
Saisho, Y.1
Butler, A.E.2
Manesso, E.3
Elashoff, D.4
Rizza, R.A.5
Butler, P.C.6
-
12
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
Morris AP, Voight BF, Teslovich TM, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44(9):981–990.
-
(2012)
Nat Genet
, vol.44
, Issue.9
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
-
13
-
-
84895858002
-
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
-
Steinthorsdottir V, Thorleifsson G, Sulem P, et al. Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes. Nat Genet. 2014;46(3):294–298.
-
(2014)
Nat Genet
, vol.46
, Issue.3
, pp. 294-298
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Sulem, P.3
-
14
-
-
0015550521
-
Effects of glucose on beta cells in pancreatic monolayer cultures
-
Chick WL, Lauris V, Flewelling JH, Andrews KA, Woodruff JM. Effects of glucose on beta cells in pancreatic monolayer cultures. Endocrinology. 1973;92(1):212–218.
-
(1973)
Endocrinology
, vol.92
, Issue.1
, pp. 212-218
-
-
Chick, W.L.1
Lauris, V.2
Flewelling, J.H.3
Andrews, K.A.4
Woodruff, J.M.5
-
15
-
-
0024508097
-
Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion
-
Bonner-Weir S, Deery D, Leahy JL, Weir GC. Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes. 1989;38(1):49–53.
-
(1989)
Diabetes
, vol.38
, Issue.1
, pp. 49-53
-
-
Bonner-Weir, S.1
Deery, D.2
Leahy, J.L.3
Weir, G.C.4
-
16
-
-
79953734660
-
Control of pancreatic β cell regeneration by glucose metabolism
-
Porat S, Weinberg-Corem N, Tornovsky-Babaey S, et al. Control of pancreatic β cell regeneration by glucose metabolism. Cell Metab. 2011;13(4):440–449.
-
(2011)
Cell Metab
, vol.13
, Issue.4
, pp. 440-449
-
-
Porat, S.1
Weinberg-Corem, N.2
Tornovsky-Babaey, S.3
-
17
-
-
33847687194
-
Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion
-
Ackermann AM, Gannon M. Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion. J Mol Endocrinol. 2007;38(1–2):193–206.
-
(2007)
J Mol Endocrinol
, vol.38
, Issue.1-2
, pp. 193-206
-
-
Ackermann, A.M.1
Gannon, M.2
-
18
-
-
84862001481
-
Adenosine signaling promotes regeneration of pancreatic β cells in vivo
-
Andersson O, Adams BA, Yoo D, et al. Adenosine signaling promotes regeneration of pancreatic β cells in vivo. Cell Metab. 2012; 15(6):885–894.
-
(2012)
Cell Metab
, vol.15
, Issue.6
, pp. 885-894
-
-
Andersson, O.1
Adams, B.A.2
Yoo, D.3
-
19
-
-
84894500766
-
Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a
-
Wei J, Hanna T, Suda N, Karsenty G, Ducy P. Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a. Diabetes. 2014;63(3):1021–1031.
-
(2014)
Diabetes
, vol.63
, Issue.3
, pp. 1021-1031
-
-
Wei, J.1
Hanna, T.2
Suda, N.3
Karsenty, G.4
Ducy, P.5
-
20
-
-
47749094308
-
Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice
-
Kim JW, Roberts CD, Berg SA, Caicedo A, Roper SD, Chaudhari N. Imaging cyclic AMP changes in pancreatic islets of transgenic reporter mice. PLoS One. 2008;3(5):e2127.
-
(2008)
PLoS One
, vol.3
, Issue.5
-
-
Kim, J.W.1
Roberts, C.D.2
Berg, S.A.3
Caicedo, A.4
Roper, S.D.5
Chaudhari, N.6
-
21
-
-
0035922142
-
PTHrP increases pancreatic beta-cell-specific functions in well-differentiated cells
-
Sawada Y, Zhang B, Okajima F, Izumi T, Takeuchi T. PTHrP increases pancreatic beta-cell-specific functions in well-differentiated cells. Mol Cell Endocrinol. 2001;182(2):265–275.
-
(2001)
Mol Cell Endocrinol
, vol.182
, Issue.2
, pp. 265-275
-
-
Sawada, Y.1
Zhang, B.2
Okajima, F.3
Izumi, T.4
Takeuchi, T.5
-
22
-
-
33645226637
-
Exendin-4 induction of cyclin D1 expression in INS-1 beta-cells: Involvement of cAMP-responsive element
-
Kim MJ, Kang JH, Park YG, et al. Exendin-4 induction of cyclin D1 expression in INS-1 beta-cells: involvement of cAMP-responsive element. J Endocrinol. 2006;188(3):623–633.
-
(2006)
J Endocrinol
, vol.188
, Issue.3
, pp. 623-633
-
-
Kim, M.J.1
Kang, J.H.2
Park, Y.G.3
-
23
-
-
0942298243
-
Prolactin, progesterone, and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6 beta-cells
-
Shao J, Qiao L, Friedman JE. Prolactin, progesterone, and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6 beta-cells. Am J Physiol. 2004; 286(2):E304–E310.
-
(2004)
Am J Physiol
, vol.286
, Issue.2
, pp. E304-E310
-
-
Shao, J.1
Qiao, L.2
Friedman, J.E.3
-
24
-
-
0027473729
-
Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon- like peptide-1(7–37)
-
Holz GG 4th, Kühtreiber WM, Habener JF. Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon- like peptide-1(7–37). Nature. 1993;361(6410):362–365.
-
(1993)
Nature
, vol.361
, Issue.6410
, pp. 362-365
-
-
Holz, G.G.1
Kühtreiber, W.M.2
Habener, J.F.3
-
25
-
-
12144290381
-
Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells
-
Inada A, Hamamoto Y, Tsuura Y, et al. Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells. Mol Cell Biol. 2004;24(7): 2831–2841.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.7
, pp. 2831-2841
-
-
Inada, A.1
Hamamoto, Y.2
Tsuura, Y.3
-
26
-
-
0345618266
-
Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes
-
Hennige AM, Burks DJ, Ozcan U, et al. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes. J Clin Invest. 2003;112(10):1521–1532.
-
(2003)
J Clin Invest
, vol.112
, Issue.10
, pp. 1521-1532
-
-
Hennige, A.M.1
Burks, D.J.2
Ozcan, U.3
-
27
-
-
33645239679
-
Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways
-
Friedrichsen BN, Neubauer N, Lee YC, et al. Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways. J Endocrinol. 2006;188(3):481–492.
-
(2006)
J Endocrinol
, vol.188
, Issue.3
, pp. 481-492
-
-
Friedrichsen, B.N.1
Neubauer, N.2
Lee, Y.C.3
-
28
-
-
0038339191
-
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2
-
Jhala US, Canettieri G, Screaton RA, et al. cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes Dev. 2003;17(13):1575–1580.
-
(2003)
Genes Dev
, vol.17
, Issue.13
, pp. 1575-1580
-
-
Jhala, U.S.1
Canettieri, G.2
Screaton, R.A.3
-
29
-
-
33749626976
-
Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation
-
Hussain MA, Porras DL, Rowe MH, et al. Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation. Mol Cell Biol. 2006;26(20):7747–7759.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.20
, pp. 7747-7759
-
-
Hussain, M.A.1
Porras, D.L.2
Rowe, M.H.3
-
30
-
-
78049446505
-
Conditional gene targeting in mouse pancreatic β-cells: Analysis of ectopic Cre transgene expression in the brain
-
Wicksteed B, Brissova M, Yan W, et al. Conditional gene targeting in mouse pancreatic β-cells: analysis of ectopic Cre transgene expression in the brain. Diabetes. 2010;59(12):3090–3098.
-
(2010)
Diabetes
, vol.59
, Issue.12
, pp. 3090-3098
-
-
Wicksteed, B.1
Brissova, M.2
Yan, W.3
-
31
-
-
33847068206
-
Overview of PDEs and their regulation
-
Omori K, Kotera J. Overview of PDEs and their regulation. Circ Res. 2007;100(3):309–327.
-
(2007)
Circ Res
, vol.100
, Issue.3
, pp. 309-327
-
-
Omori, K.1
Kotera, J.2
-
32
-
-
10044294739
-
Targeting beta-cell cyclic 3β5β adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review
-
Furman B, Pyne N, Flatt P, O’Harte F. Targeting beta-cell cyclic 3β5β adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review. J Pharm Pharmacol. 2004;56(12):1477–1492.
-
(2004)
J Pharm Pharmacol
, vol.56
, Issue.12
, pp. 1477-1492
-
-
Furman, B.1
Pyne, N.2
Flatt, P.3
O’Harte, F.4
-
33
-
-
78649816005
-
Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets
-
Heimann E, Jones HA, Resjo S, Manganiello VC, Stenson L, Degerman E. Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets. PLoS One. 2010; 5(12):e14191.
-
(2010)
PLoS One
, vol.5
, Issue.12
-
-
Heimann, E.1
Jones, H.A.2
Resjo, S.3
Manganiello, V.C.4
Stenson, L.5
Degerman, E.6
-
34
-
-
51249111507
-
Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets
-
Waddleton D, Wu W, Feng Y, et al. Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets. Biochem Pharmacol. 2008;76(7):884–893.
-
(2008)
Biochem Pharmacol
, vol.76
, Issue.7
, pp. 884-893
-
-
Waddleton, D.1
Wu, W.2
Feng, Y.3
-
35
-
-
0019135636
-
Cyclic adenosine- 3β,5β-monophosphate stimulates islet B cell replication in neonatal rat pancreatic monolayer cultures
-
Rabinovitch A, Blondel B, Murray T, Mintz DH. Cyclic adenosine- 3β,5β-monophosphate stimulates islet B cell replication in neonatal rat pancreatic monolayer cultures. J Clin Invest. 1980;66(5):1065– 1071.
-
(1980)
J Clin Invest
, vol.66
, Issue.5
, pp. 1065-1071
-
-
Rabinovitch, A.1
Blondel, B.2
Murray, T.3
Mintz, D.H.4
-
36
-
-
0141505057
-
Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin
-
Abdollahi M, Chan TS, Subrahmanyam V, O’Brien PJ. Effects of phosphodiesterase 3,4,5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and susceptibility to a mitochondrial toxin. Mol Cell Biochem. 2003;252(1–2):205–211.
-
(2003)
Mol Cell Biochem
, vol.252
, Issue.1-2
, pp. 205-211
-
-
Abdollahi, M.1
Chan, T.S.2
Subrahmanyam, V.3
O’brien, P.J.4
-
37
-
-
37649025080
-
Beta cell-specific deficiency of the stimulatoryGprotein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes
-
Xie T, Chen M, Zhang QH, Ma Z, Weinstein LS. Beta cell-specific deficiency of the stimulatoryGprotein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes. Proc Natl Acad U S A. 2007;104(49):19601–19606.
-
(2007)
Proc Natl Acad U S A
, vol.104
, Issue.49
, pp. 19601-19606
-
-
Xie, T.1
Chen, M.2
Zhang, Q.H.3
Ma, Z.4
Weinstein, L.S.5
-
38
-
-
8844281542
-
Altered glucose homeostasis in alpha2A-adrenoceptor knockout mice
-
Fagerholm V, Gronroos T, Marjamaki P, Viljanen T, Scheinin M, Haaparanta M. Altered glucose homeostasis in alpha2A-adrenoceptor knockout mice. Eur J Pharmacol. 2004;505(1–3):243–252.
-
(2004)
Eur J Pharmacol
, vol.505
, Issue.1-3
, pp. 243-252
-
-
Fagerholm, V.1
Gronroos, T.2
Marjamaki, P.3
Viljanen, T.4
Scheinin, M.5
Haaparanta, M.6
-
39
-
-
0029670443
-
Expression of alpha 2- and beta-adrenoceptor subtypes in human islets of Langerhans
-
Lacey RJ, Chan SL, Cable HC, et al. Expression of alpha 2- and beta-adrenoceptor subtypes in human islets of Langerhans. J Endocrinol. 1996;148(3):531–543.
-
(1996)
J Endocrinol
, vol.148
, Issue.3
, pp. 531-543
-
-
Lacey, R.J.1
Chan, S.L.2
Cable, H.C.3
-
40
-
-
36849052080
-
Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion
-
Regard JB, Kataoka H, Cano DA, et al. Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion. J Clin Invest. 2007;117(12):4034–4043.
-
(2007)
J Clin Invest
, vol.117
, Issue.12
, pp. 4034-4043
-
-
Regard, J.B.1
Kataoka, H.2
Cano, D.A.3
-
41
-
-
74249123937
-
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes
-
Rosengren AH, Jokubka R, Tojjar D, et al. Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes. Science. 2010;327(5962):217–220.
-
(2010)
Science
, vol.327
, Issue.5962
, pp. 217-220
-
-
Rosengren, A.H.1
Jokubka, R.2
Tojjar, D.3
-
42
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
Dupuis J, Langenberg C, Prokopenko I, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42(2):105–116.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
-
43
-
-
79959727732
-
Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: Meta-analysis of four prospective studies
-
Talmud PJ, Cooper JA, Gaunt T, et al. Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies. Diabetologia. 2011;54(7):1710–1719.
-
(2011)
Diabetologia
, vol.54
, Issue.7
, pp. 1710-1719
-
-
Talmud, P.J.1
Cooper, J.A.2
Gaunt, T.3
-
44
-
-
0023224147
-
Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection
-
Gotoh M, Maki T, Satomi S, et al. Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplantation. 1987;43(5): 725–730.
-
(1987)
Transplantation
, vol.43
, Issue.5
, pp. 725-730
-
-
Gotoh, M.1
Maki, T.2
Satomi, S.3
-
45
-
-
84950646761
-
The influence curve and its role in robust estimation
-
Hampel AF. The influence curve and its role in robust estimation. J Am Statist Assoc. 1974;69(346):383.
-
(1974)
J Am Statist Assoc
, vol.69
, Issue.346
, pp. 383
-
-
Hampel, A.F.1
-
46
-
-
84857972319
-
Adenosine kinase inhibition selectively promotes rodent and porcine islet beta-cell replication
-
Annes JP, Ryu JH, Lam K, et al. Adenosine kinase inhibition selectively promotes rodent and porcine islet beta-cell replication. Proc Natl Acad U S A. 2012;109(10):3915–3920.
-
(2012)
Proc Natl Acad U S A
, vol.109
, Issue.10
, pp. 3915-3920
-
-
Annes, J.P.1
Ryu, J.H.2
Lam, K.3
-
47
-
-
0029166081
-
The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loophelix factor binding site
-
Serup P, Petersen HV, Pedersen EE, et al. The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loophelix factor binding site. Biochem J. 1995;310(Pt 3):997–1003.
-
(1995)
Biochem J
, vol.310
, pp. 997-1003
-
-
Serup, P.1
Petersen, H.V.2
Pedersen, E.E.3
-
48
-
-
84865596106
-
Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets
-
Rieck S, Zhang J, Li Z, et al. Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets. Mol Endocrinol. 2012;26(9): 1590–1602.
-
(2012)
Mol Endocrinol
, vol.26
, Issue.9
, pp. 1590-1602
-
-
Rieck, S.1
Zhang, J.2
Li, Z.3
-
49
-
-
80455143204
-
Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells
-
Lee SH, Hao E, Levine F, Itkin-Ansari P. Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells. Islets. 2011;3(6):358–366.
-
(2011)
Islets
, vol.3
, Issue.6
, pp. 358-366
-
-
Lee, S.H.1
Hao, E.2
Levine, F.3
Itkin-Ansari, P.4
-
50
-
-
40949118132
-
Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator- alpha and DUSP14
-
Klinger S, Poussin C, Debril MB, Dolci W, Halban PA, Thorens B. Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator- alpha and DUSP14. Diabetes. 2008;57(3):584–593.
-
(2008)
Diabetes
, vol.57
, Issue.3
, pp. 584-593
-
-
Klinger, S.1
Poussin, C.2
Debril, M.B.3
Dolci, W.4
Halban, P.A.5
Thorens, B.6
-
51
-
-
70350445535
-
Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia
-
Grauer SM, Pulito VL, Navarra RL, et al. Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia. J Pharmacol Exp Ther. 2009; 331(2):574–590.
-
(2009)
J Pharmacol Exp Ther
, vol.331
, Issue.2
, pp. 574-590
-
-
Grauer, S.M.1
Pulito, V.L.2
Navarra, R.L.3
-
53
-
-
31144458770
-
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells
-
Dyachok O, Isakov Y, Sågetorp J, Tengholm A. Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells. Nature. 2006;439(7074):349–352.
-
(2006)
Nature
, vol.439
, Issue.7074
, pp. 349-352
-
-
Dyachok, O.1
Isakov, Y.2
Sågetorp, J.3
Tengholm, A.4
-
54
-
-
84876532885
-
β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion
-
Kaihara KA, Dickson LM, Jacobson DA, et al. β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion. Diabetes. 2013;62(5): 1527–1536.
-
(2013)
Diabetes
, vol.62
, Issue.5
, pp. 1527-1536
-
-
Kaihara, K.A.1
Dickson, L.M.2
Jacobson, D.A.3
-
55
-
-
0034001450
-
Autonomic regulation of islet hormone secretion–implications for health and disease
-
Ahrén B. Autonomic regulation of islet hormone secretion–implications for health and disease. Diabetologia. 2000;43(4):393–410.
-
(2000)
Diabetologia
, vol.43
, Issue.4
, pp. 393-410
-
-
Ahrén, B.1
-
56
-
-
0014750154
-
Effect of alphaadrenergic blockade on insulin secretion in man
-
Buse MG, Johnson AH, Kuperminc D, Buse J. Effect of alphaadrenergic blockade on insulin secretion in man. Metab Clin Exp. 1970;19(3):219–225.
-
(1970)
Metab Clin Exp
, vol.19
, Issue.3
, pp. 219-225
-
-
Buse, M.G.1
Johnson, A.H.2
Kuperminc, D.3
Buse, J.4
-
57
-
-
0142247456
-
Inhibition of insulin secretion via distinct signaling pathways in alpha2- adrenoceptor knockout mice
-
Peterhoff M, Sieg A, Brede M, Chao CM, Hein L, Ullrich S. Inhibition of insulin secretion via distinct signaling pathways in alpha2- adrenoceptor knockout mice. Eur J Endocrinol. 2003;149(4):343– 350.
-
(2003)
Eur J Endocrinol
, vol.149
, Issue.4
, pp. 343-350
-
-
Peterhoff, M.1
Sieg, A.2
Brede, M.3
Chao, C.M.4
Hein, L.5
Ullrich, S.6
-
58
-
-
0022370763
-
Expression of both alpha 1- and alpha 2-adrenoceptors in an insulin-secreting cell line. Parallel studies of cytosolic free Ca2+ and insulin release
-
Ullrich S, Wollheim CB. Expression of both alpha 1- and alpha 2-adrenoceptors in an insulin-secreting cell line. Parallel studies of cytosolic free Ca2+ and insulin release. Mol Pharmacol. 1985; 28(2):100–106.
-
(1985)
Mol Pharmacol
, vol.28
, Issue.2
, pp. 100-106
-
-
Ullrich, S.1
Wollheim, C.B.2
-
59
-
-
0033513455
-
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
-
Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes. 1999;48(12):2270–2276.
-
(1999)
Diabetes
, vol.48
, Issue.12
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
-
60
-
-
81455142483
-
Stimulating β-cell replication and improving islet graft function by AR231453, a GPR119 agonist
-
Gao J, Tian L, Weng G, O’Brien TD, Luo J, Guo Z. Stimulating β-cell replication and improving islet graft function by AR231453, a GPR119 agonist. Transplant Proc. 2011;43(9):3217–3220.
-
(2011)
Transplant Proc
, vol.43
, Issue.9
, pp. 3217-3220
-
-
Gao, J.1
Tian, L.2
Weng, G.3
O’Brien, T.D.4
Luo, J.5
Guo, Z.6
-
61
-
-
78650073823
-
Parathyroid hormone-related protein enhances human β-cell proliferation and function with associated induction of cyclin-dependent kinase 2 and cyclin E expression
-
Guthalu Kondegowda N, Joshi-Gokhale S, Harb G, et al. Parathyroid hormone-related protein enhances human β-cell proliferation and function with associated induction of cyclin-dependent kinase 2 and cyclin E expression. Diabetes. 2010;59(12):3131–3138.
-
(2010)
Diabetes
, vol.59
, Issue.12
, pp. 3131-3138
-
-
Guthalu Kondegowda, N.1
Joshi-Gokhale, S.2
Harb, G.3
-
62
-
-
17644387563
-
Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth
-
Kushner JA, Ciemerych MA, Sicinska E, et al. Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth. Mol Cell Biol. 2005;25(9):3752–3762.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.9
, pp. 3752-3762
-
-
Kushner, J.A.1
Ciemerych, M.A.2
Sicinska, E.3
-
63
-
-
34948821871
-
Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells
-
Zhong L, Georgia S, Tschen SI, Nakayama K, Nakayama K, Bhushan A. Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells. J Clin Invest. 2007;117(10):2869–2876.
-
(2007)
J Clin Invest
, vol.117
, Issue.10
, pp. 2869-2876
-
-
Zhong, L.1
Georgia, S.2
Tschen, S.I.3
Nakayama, K.4
Nakayama, K.5
Bhushan, A.6
-
64
-
-
82055191839
-
Skp2 is required for incretin hormone-mediated β-cell proliferation
-
Tschen SI, Georgia S, Dhawan S, Bhushan A. Skp2 is required for incretin hormone-mediated β-cell proliferation. Mol Endocrinol. 2011;25(12):2134–2143.
-
(2011)
Mol Endocrinol
, vol.25
, Issue.12
, pp. 2134-2143
-
-
Tschen, S.I.1
Georgia, S.2
Dhawan, S.3
Bhushan, A.4
-
65
-
-
52749096469
-
Exendin-4 stimulation of cyclin A2 in beta-cell proliferation
-
Song WJ, Schreiber WE, Zhong E, et al. Exendin-4 stimulation of cyclin A2 in beta-cell proliferation. Diabetes. 2008;57(9):2371– 2381.
-
(2008)
Diabetes
, vol.57
, Issue.9
, pp. 2371-2381
-
-
Song, W.J.1
Schreiber, W.E.2
Zhong, E.3
-
66
-
-
77953957372
-
Cyclic AMP signaling in pancreatic islets
-
Furman B, Ong WK, Pyne NJ. Cyclic AMP signaling in pancreatic islets. Adv Exp Med Biol. 2010;654:281–304.
-
(2010)
Adv Exp Med Biol
, vol.654
, pp. 281-304
-
-
Furman, B.1
Ong, W.K.2
Pyne, N.J.3
-
67
-
-
33845348168
-
Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice
-
Choi YH, Park S, Hockman S, Zmuda-Trzebiatowska E, et al. Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice. J Clin Invest. 2006;116(12): 3240–3251.
-
(2006)
J Clin Invest
, vol.116
, Issue.12
, pp. 3240-3251
-
-
Choi, Y.H.1
Park, S.2
Hockman, S.3
Zmuda-Trzebiatowska, E.4
-
68
-
-
84891811147
-
Genetic deletion and pharmacological inhibition of phosphodiesterase 10A protects mice from diet-induced obesity and insulin resistance
-
Nawrocki AR, Rodriguez CG, Toolan DM, et al. Genetic deletion and pharmacological inhibition of phosphodiesterase 10A protects mice from diet-induced obesity and insulin resistance. Diabetes. 2014;63(1):300–311.
-
(2014)
Diabetes
, vol.63
, Issue.1
, pp. 300-311
-
-
Nawrocki, A.R.1
Rodriguez, C.G.2
Toolan, D.M.3
-
69
-
-
0038287034
-
Catechol-O-methyltransferase (COMT): Biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors
-
Männistö PT, Kaakkola S. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Pharmacol Rev. 1999;51(4):593–628.
-
(1999)
Pharmacol Rev
, vol.51
, Issue.4
, pp. 593-628
-
-
Männistö, P.T.1
Kaakkola, S.2
-
70
-
-
84893870589
-
Targeting the cell cycle inhibitor p57Kip2 promotes adult human β cell replication
-
Avrahami D, Li C, Yu M, Jiao Y, Zhang J, Naji A, Ziaie S, Glaser B, Kaestner KH. Targeting the cell cycle inhibitor p57Kip2 promotes adult human β cell replication. J Clin Invest. 2014;124(2): 670–674.
-
(2014)
J Clin Invest
, vol.124
, Issue.2
, pp. 670-674
-
-
Avrahami, D.1
Li, C.2
Yu, M.3
Jiao, Y.4
Zhang, J.5
Naji, A.6
Ziaie, S.7
Glaser, B.8
Kaestner, K.H.9
-
71
-
-
77649096355
-
Glucose tolerance in depressed inpatients, under treatment with mirtazapine and in healthy controls
-
Hennings JM, Ising M, Grautoff S, Himmerich H, Pollmächer T, Schaaf L. Glucose tolerance in depressed inpatients, under treatment with mirtazapine and in healthy controls. Exp Clin Endocrinol Diabetes. 2010;118(2):98–100.
-
(2010)
Exp Clin Endocrinol Diabetes
, vol.118
, Issue.2
, pp. 98-100
-
-
Hennings, J.M.1
Ising, M.2
Grautoff, S.3
Himmerich, H.4
Pollmächer, T.5
Schaaf, L.6
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