메뉴 건너뛰기




Volumn 121, Issue 9, 2014, Pages 1081-1106

Glutamatergic candidate genes in autism spectrum disorder: An overview

Author keywords

ASD; Genetic studies; Glutamtergic pathway; Review

Indexed keywords

AMPA RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; IONOTROPIC RECEPTOR; METABOTROPIC RECEPTOR;

EID: 84907597101     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-014-1161-y     Document Type: Review
Times cited : (22)

References (197)
  • 3
    • 0029031548 scopus 로고
    • Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro
    • Ambrosini A, Bresciani L, Fracchia S, Brunello N, Racagni G (1995) Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro. Mol Pharmacol 47(5):1057-1064
    • (1995) Mol Pharmacol , vol.47 , Issue.5 , pp. 1057-1064
    • Ambrosini, A.1    Bresciani, L.2    Fracchia, S.3    Brunello, N.4    Racagni, G.5
  • 5
    • 0033779559 scopus 로고    scopus 로고
    • Astrocyte glutamate transport: Review of properties, regulation, and physiological functions
    • Anderson CM, Swanson RA (2000) Astrocyte glutamate transport: review of properties, regulation, and physiological functions. Glia 32(1):1-14
    • (2000) Glia , vol.32 , Issue.1 , pp. 1-14
    • Anderson, C.M.1    Swanson, R.A.2
  • 9
    • 33745818375 scopus 로고    scopus 로고
    • Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: The Special Needs and Autism Project (SNAP)
    • DOI 10.1016/S0140-6736(06)69041-7, PII S0140673606690417
    • Baird G, Simonoff E, Pickles A, Chandler S, Loucas T, Meldrum D, Charman T (2006) Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). Lancet 368(9531):210-215 (Pubitemid 44037796)
    • (2006) Lancet , vol.368 , Issue.9531 , pp. 210-215
    • Baird, G.1    Simonoff, E.2    Pickles, A.3    Chandler, S.4    Loucas, T.5    Meldrum, D.6    Charman, T.7
  • 12
    • 67349224993 scopus 로고    scopus 로고
    • Gene regulation by voltage-dependent calcium channels
    • Barbado M, Fablet K, Ronjat M, de Waard M (2009) Gene regulation by voltage-dependent calcium channels. Biochim Biophys Acta 1793(6):1096-1104
    • (2009) Biochim Biophys Acta , vol.1793 , Issue.6 , pp. 1096-1104
    • Barbado, M.1    Fablet, K.2    Ronjat, M.3    De Waard, M.4
  • 13
    • 18944370955 scopus 로고    scopus 로고
    • Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: Evidence of association at GRIN2A and ABAT
    • DOI 10.1086/430454
    • Barnby G, Abbott A, Sykes N, Morris A, Weeks DE, Mott R, Lamb J, Bailey AJ, Monaco AP (2005) Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: evidence of Association at GRIN2A and ABATevidence of association at GRIN2A and ABAT. Am J Hum Genet 76(6):950-966 (Pubitemid 40705432)
    • (2005) American Journal of Human Genetics , vol.76 , Issue.6 , pp. 950-966
    • Barnby, G.1    Abbott, A.2    Sykes, N.3    Morris, A.4    Weeks, D.E.5    Mott, R.6    Lamb, J.7    Bailey, A.J.8    Monaco, A.P.9
  • 14
    • 75149162868 scopus 로고    scopus 로고
    • Two patients with EP300 mutations and facial dysmorphism different from the classic Rubinstein-Taybi syndrome
    • Bartsch O, Labonté J, Albrecht B, Wieczorek D, Lechno S, Zechner U, Haaf T (2010) Two patients with EP300 mutations and facial dysmorphism different from the classic Rubinstein-Taybi syndrome. Am J Med Genet A 152A(1):181-184
    • (2010) Am J Med Genet A , vol.152 A , Issue.1 , pp. 181-184
    • Bartsch, O.1    Labonté, J.2    Albrecht, B.3    Wieczorek, D.4    Lechno, S.5    Zechner, U.6    Haaf, T.7
  • 15
    • 53849110899 scopus 로고    scopus 로고
    • Fragile X syndrome: Loss of local mRNA regulation alters synaptic development and function
    • Bassell GJ, Warren ST (2008) Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. Neuron 60(2):201-214
    • (2008) Neuron , vol.60 , Issue.2 , pp. 201-214
    • Bassell, G.J.1    Warren, S.T.2
  • 17
    • 84877344739 scopus 로고    scopus 로고
    • Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis
    • Bateup HS, Johnson CA, Denefrio CL, Saulnier JL, Kornacker K, Sabatini BL (2013) Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis. Neuron 78(3):510-522
    • (2013) Neuron , vol.78 , Issue.3 , pp. 510-522
    • Bateup, H.S.1    Johnson, C.A.2    Denefrio, C.L.3    Saulnier, J.L.4    Kornacker, K.5    Sabatini, B.L.6
  • 19
    • 3042647610 scopus 로고    scopus 로고
    • The mGluR theory of fragile X mental retardation
    • DOI 10.1016/j.tins.2004.04.009, PII S0166223604001328
    • Bear MF, Huber KM, Warren ST (2004) The mGluR theory of fragile X mental retardation. Trends Neurosci 27(7):370-377 (Pubitemid 38829251)
    • (2004) Trends in Neurosciences , vol.27 , Issue.7 , pp. 370-377
    • Bear, M.F.1    Huber, K.M.2    Warren, S.T.3
  • 21
    • 79952313620 scopus 로고    scopus 로고
    • Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting
    • Betancur C (2011) Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting. Brain Res 1380:42-77
    • (2011) Brain Res , vol.1380 , pp. 42-77
    • Betancur, C.1
  • 26
    • 0025326163 scopus 로고
    • Calcium-dependent regulation of protein synthesis in intact mammalian cells
    • Brostrom CO, Brostrom MA (1990) Calcium-dependent regulation of protein synthesis in intact mammalian cells. Annu Rev Physiol 52:577-590 (Pubitemid 20103556)
    • (1990) Annual Review of Physiology , vol.52 , pp. 577-590
    • Brostrom, C.O.1    Brostrom, M.A.2
  • 29
    • 1542284674 scopus 로고    scopus 로고
    • Linkage analysis for autism in a subset families with obsessive-compulsive behaviors: Evidence for an autism susceptibility gene on chromosome 1 and further support for susceptibility genes on chromosome 6 and 19
    • DOI 10.1038/sj.mp.4001465
    • Buxbaum JD, Silverman J, Keddache M, Smith CJ, Hollander E, Ramoz N, Reichert JG (2004) Linkage analysis for autism in a subset families with obsessive-compulsive behaviors. Evidence for an autism susceptibility gene on chromosome 1 and further support for susceptibility genes on chromosome 6 and 19. Mol Psychiatry 9(2):144-150 (Pubitemid 38299527)
    • (2004) Molecular Psychiatry , vol.9 , Issue.2 , pp. 144-150
    • Buxbaum, J.D.1    Silverman, J.2    Keddache, M.3    Smith, C.J.4    Hollander, E.5    Ramoz, N.6    Reichert, J.G.7
  • 30
    • 84855541549 scopus 로고    scopus 로고
    • Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders
    • Carlson GC (2012) Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders. Pharmacol Biochem Behav 100(4):850-854
    • (2012) Pharmacol Biochem Behav , vol.100 , Issue.4 , pp. 850-854
    • Carlson, G.C.1
  • 32
    • 73149102059 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, United States, 2006
    • Centers for Disease Control and Prevention (CDC)
    • Centers for Disease Control and Prevention (CDC) (2009) Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, United States, 2006. MMWR Surveill Summ 58(10):1-20
    • (2009) MMWR Surveill Summ , vol.58 , Issue.10 , pp. 1-20
  • 33
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • DOI 10.1126/science.1153252
    • Chahrour M, Jung SY, Shaw C, Zhou X, Wong Stephen T C, Qin J, Zoghbi HY (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320(5880):1224-1229 (Pubitemid 351929512)
    • (2008) Science , vol.320 , Issue.5880 , pp. 1224-1229
    • Chahrour, M.1    Sung, Y.J.2    Shaw, C.3    Zhou, X.4    Wong, S.T.C.5    Qin, J.6    Zoghbi, H.Y.7
  • 34
    • 34748831111 scopus 로고    scopus 로고
    • MeCP2 Controls Excitatory Synaptic Strength by Regulating Glutamatergic Synapse Number
    • DOI 10.1016/j.neuron.2007.08.018, PII S0896627307006472
    • Chao HT, Zoghbi HY, Rosenmund C (2007) MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number. Neuron 56(1):58-65 (Pubitemid 47484176)
    • (2007) Neuron , vol.56 , Issue.1 , pp. 58-65
    • Chao, H.-T.1    Zoghbi, H.Y.2    Rosenmund, C.3
  • 35
    • 77956908654 scopus 로고    scopus 로고
    • A de novo 7.9 Mb deletion in 22q13.2 → qter in a boy with autistic features, epilepsy, developmental delay, atopic dermatitis and abnormal immunological findings
    • Chen C, Lin S, Chern S, Tsai F, Wu P, Lee C, Chen Y, Chen W, Wang W (2010) A de novo 7.9 Mb deletion in 22q13.2 → qter in a boy with autistic features, epilepsy, developmental delay, atopic dermatitis and abnormal immunological findings. Eur J Med Genet 53(5):329-332
    • (2010) Eur J Med Genet , vol.53 , Issue.5 , pp. 329-332
    • Chen, C.1    Lin, S.2    Chern, S.3    Tsai, F.4    Wu, P.5    Lee, C.6    Chen, Y.7    Chen, W.8    Wang, W.9
  • 39
    • 84855528326 scopus 로고    scopus 로고
    • Glutamate mediated signaling in the pathophysiology of autism spectrum disorders
    • Choudhury PR, Lahiri S, Rajamma U (2012) Glutamate mediated signaling in the pathophysiology of autism spectrum disorders. Pharmacol Biochem Behav 100(4):841-849
    • (2012) Pharmacol Biochem Behav , vol.100 , Issue.4 , pp. 841-849
    • Choudhury, P.R.1    Lahiri, S.2    Rajamma, U.3
  • 41
    • 0034613308 scopus 로고    scopus 로고
    • Quisqualate induces an inward current via mGluR activation in neocortical pyramidal neurons
    • Chu Z, Hablitz JJ (2000) Quisqualate induces an inward current via mGluR activation in neocortical pyramidal neurons. Brain Res 879(1-2):88-92
    • (2000) Brain Res , vol.879 , Issue.1-2 , pp. 88-92
    • Chu, Z.1    Hablitz, J.J.2
  • 45
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt NC (2001) Glutamate uptake. Prog Neurobiol 65(1):1-105
    • (2001) Prog Neurobiol , vol.65 , Issue.1 , pp. 1-105
    • Danbolt, N.C.1
  • 49
    • 84862493260 scopus 로고    scopus 로고
    • Genetic architecture in autism spectrum disorder
    • Devlin B, Scherer SW (2012) Genetic architecture in autism spectrum disorder. Curr Opin Genet Dev 22(3):229-237
    • (2012) Curr Opin Genet Dev , vol.22 , Issue.3 , pp. 229-237
    • Devlin, B.1    Scherer, S.W.2
  • 50
    • 0012662271 scopus 로고    scopus 로고
    • The roles of metabotropic glutamate receptors in seizures and epilepsy
    • Doherty J, Dingledine R (2002) The roles of metabotropic glutamate receptors in seizures and epilepsy. Curr Drug Targets CNS Neurol Disord 1(3):251-260
    • (2002) Curr Drug Targets CNS Neurol Disord , vol.1 , Issue.3 , pp. 251-260
    • Doherty, J.1    Dingledine, R.2
  • 52
    • 84884955739 scopus 로고    scopus 로고
    • Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism
    • Duffney LJ, Wei J, Cheng J, Liu W, Smith KR, Kittler JT, Yan Z (2013) Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism. J Neurosci 33(40):15767-15778
    • (2013) J Neurosci , vol.33 , Issue.40 , pp. 15767-15778
    • Duffney, L.J.1    Wei, J.2    Cheng, J.3    Liu, W.4    Smith, K.R.5    Kittler, J.T.6    Yan, Z.7
  • 54
    • 84855341900 scopus 로고    scopus 로고
    • SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism
    • Durand CM, Perroy J, Loll F, Perrais D, Fagni L, Bourgeron T, Montcouquiol M, Sans N (2012) SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism. Mol Psychiatry 17(1):71-84
    • (2012) Mol Psychiatry , vol.17 , Issue.1 , pp. 71-84
    • Durand, C.M.1    Perroy, J.2    Loll, F.3    Perrais, D.4    Fagni, L.5    Bourgeron, T.6    Montcouquiol, M.7    Sans, N.8
  • 57
    • 33847170993 scopus 로고    scopus 로고
    • A retrospective study of memantine in children and adolescents with pervasive developmental disorders
    • DOI 10.1007/s00213-006-0518-9, Pediatric Psychopharmacology
    • Erickson CA, Posey DJ, Stigler KA, Mullett J, Katschke AR, McDougle CJ (2007) A retrospective study of memantine in children and adolescents with pervasive developmental disorders. Psychopharmacology 191(1):141-147 (Pubitemid 46294942)
    • (2007) Psychopharmacology , vol.191 , Issue.1 , pp. 141-147
    • Erickson, C.A.1    Posey, D.J.2    Stigler, K.A.3    Mullett, J.4    Katschke, A.R.5    McDougle, C.J.6
  • 58
    • 39749165772 scopus 로고    scopus 로고
    • The hyperglutamatergic hypothesis of autism
    • author reply 912-3
    • Fatemi SH (2008) The hyperglutamatergic hypothesis of autism. Prog Neuropsychopharmacol Biol Psychiatry 32(3):911 (author reply 912-3)
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , Issue.3 , pp. 911
    • Fatemi, S.H.1
  • 61
    • 67049118065 scopus 로고    scopus 로고
    • Epidemiology of pervasive developmental disorders
    • Fombonne E (2009) Epidemiology of pervasive developmental disorders. Pediatr Res 65(6):591-598
    • (2009) Pediatr Res , vol.65 , Issue.6 , pp. 591-598
    • Fombonne, E.1
  • 62
    • 84860491375 scopus 로고    scopus 로고
    • Autistische Störungen - State-of-the-art und neuere Entwicklungen (autistic disorders - the state of the art and recent findings: Epidemiology, aetiology, diagnostic criteria, and therapeutic interventions)
    • quiz 148-9
    • Freitag CM (2012) Autistische Störungen - state-of-the-art und neuere Entwicklungen (autistic disorders - the state of the art and recent findings: epidemiology, aetiology, diagnostic criteria, and therapeutic interventions). Z Kinder Jugendpsychiatr Psychother 40(3):139-148 (quiz 148-9)
    • (2012) Z Kinder Jugendpsychiatr Psychother , vol.40 , Issue.3 , pp. 139-148
    • Freitag, C.M.1
  • 65
    • 79958035893 scopus 로고    scopus 로고
    • Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses
    • Gilman SR, Iossifov I, Levy D, Ronemus M, Wigler M, Vitkup D (2011) Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron 70(5):898-907
    • (2011) Neuron , vol.70 , Issue.5 , pp. 898-907
    • Gilman, S.R.1    Iossifov, I.2    Levy, D.3    Ronemus, M.4    Wigler, M.5    Vitkup, D.6
  • 71
    • 0025360106 scopus 로고
    • Genomic imprinting: Review and relevance to human diseases
    • Hall JG (1990) Genomic imprinting: review and relevance to human diseases. Am J Hum Genet 46(5):857-873
    • (1990) Am J Hum Genet , vol.46 , Issue.5 , pp. 857-873
    • Hall, J.G.1
  • 75
    • 84873644391 scopus 로고    scopus 로고
    • Amantadine: A review of use in child and adolescent psychiatry
    • Hosenbocus S, Chahal R (2013a) Amantadine: a review of use in child and adolescent psychiatry. J Can Acad Child Adolesc Psychiatry 22(1):55-60
    • (2013) J Can Acad Child Adolesc Psychiatry , vol.22 , Issue.1 , pp. 55-60
    • Hosenbocus, S.1    Chahal, R.2
  • 76
    • 84876933750 scopus 로고    scopus 로고
    • Memantine: A review of possible uses in child and adolescent psychiatry
    • Hosenbocus S, Chahal R (2013b) Memantine: a review of possible uses in child and adolescent psychiatry. J Can Acad Child Adolesc Psychiatry 22(2):166-171
    • (2013) J Can Acad Child Adolesc Psychiatry , vol.22 , Issue.2 , pp. 166-171
    • Hosenbocus, S.1    Chahal, R.2
  • 77
    • 84884338166 scopus 로고    scopus 로고
    • The genetic landscapes of autism spectrum disorders
    • Huguet G, Ey E, Bourgeron T (2013) The genetic landscapes of autism spectrum disorders. Annu Rev Genomics Hum Genet 14(1):130722103900008
    • (2013) Annu Rev Genomics Hum Genet , vol.14 , Issue.1 , pp. 130722103900008
    • Huguet, G.1    Ey, E.2    Bourgeron, T.3
  • 79
    • 6844251000 scopus 로고    scopus 로고
    • A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of AutismConsortium
    • IMGSAC
    • IMGSAC (1998) A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of AutismConsortium.HumMol Genet 7(3):571-578
    • (1998) HumMol Genet , vol.7 , Issue.3 , pp. 571-578
  • 80
    • 0034883367 scopus 로고    scopus 로고
    • A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q, and 16p
    • IMGSAC
    • IMGSAC (2001a) A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q, and 16p. Am J Hum Genet 69(3):570-581
    • (2001) Am J Hum Genet , vol.69 , Issue.3 , pp. 570-581
  • 81
    • 0035871209 scopus 로고    scopus 로고
    • Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q
    • IMGSAC
    • IMGSAC (2001b) Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q. Hum Mol Genet 10(9):973-982
    • (2001) Hum Mol Genet , vol.10 , Issue.9 , pp. 973-982
  • 86
    • 33744919546 scopus 로고    scopus 로고
    • Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway
    • DOI 10.1158/0008-5472.CAN-05-4510
    • Jiang X, Yeung RS (2006) Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway. Cancer Res 66(10):5258-5269 (Pubitemid 43844950)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5258-5269
    • Jiang, X.1    Yeung, R.S.2
  • 88
    • 70350719241 scopus 로고    scopus 로고
    • Autism spectrum conditions in individuals with Möbius sequence, CHARGE syndrome and oculo-auriculo-vertebral spectrum: Diagnostic aspects
    • Johansson M, Gillberg C, Råstam M (2010) Autism spectrum conditions in individuals with Möbius sequence, CHARGE syndrome and oculo-auriculo-vertebral spectrum: diagnostic aspects. Res Dev Disabil 31(1):9-24
    • (2010) Res Dev Disabil , vol.31 , Issue.1 , pp. 9-24
    • Johansson, M.1    Gillberg, C.2    Råstam, M.3
  • 89
    • 54949144402 scopus 로고    scopus 로고
    • The autistic neuron: Troubled translation?
    • Kelleher RJ, Bear MF (2008) The autistic neuron: troubled translation? Cell 135(3):401-406
    • (2008) Cell , vol.135 , Issue.3 , pp. 401-406
    • Kelleher, R.J.1    Bear, M.F.2
  • 90
    • 5344244073 scopus 로고    scopus 로고
    • Translational regulatory mechanisms in persistent forms of synaptic plasticity
    • DOI 10.1016/j.neuron.2004.09.013, PII S0896627304006063
    • Kelleher RJ, Govindarajan A, Tonegawa S (2004) Translational regulatory mechanisms in persistent forms of synaptic plasticity. Neuron 44(1):59-73 (Pubitemid 39348830)
    • (2004) Neuron , vol.44 , Issue.1 , pp. 59-73
    • Kelleher III, R.J.1    Govindarajan, A.2    Tonegawa, S.3
  • 93
    • 34447249472 scopus 로고    scopus 로고
    • Family-based association study between GRIK2 polymorphisms and autism spectrum disorders in the Korean trios
    • DOI 10.1016/j.neures.2007.03.002, PII S0168010207001113
    • Kim SA, Kim JH, Park M, Cho IH, Yoo HJ (2007) Family-based association study between GRIK2 polymorphisms and autism spectrum disorders in the Korean trios. Neurosci Res 58(3):332-335 (Pubitemid 47042267)
    • (2007) Neuroscience Research , vol.58 , Issue.3 , pp. 332-335
    • Kim, S.A.1    Kim, J.H.2    Park, M.3    Cho, I.H.4    Yoo, H.J.5
  • 100
    • 32844454862 scopus 로고    scopus 로고
    • A genome-wide search for alleles and haplotypes associated with autism and related pervasive developmental disorders on the Faroe Islands
    • DOI 10.1038/sj.mp.4001754, PII 4001754
    • Lauritsen MB, Als TD, Dahl HA, Flint TJ, Wang AG, Vang M, Kruse TA, Ewald H, Mors O (2006) A genome-wide search for alleles and haplotypes associated with autism and related pervasive developmental disorders on the Faroe Islands. Mol Psychiatry 11(1):37-46 (Pubitemid 43251086)
    • (2006) Molecular Psychiatry , vol.11 , Issue.1 , pp. 37-46
    • Lauritsen, M.B.1    Als, T.D.2    Dahl, H.A.3    Flint, T.J.4    Wang, A.G.5    Vang, M.6    Kruse, T.A.7    Ewald, H.8    Mors, O.9
  • 102
    • 84877926095 scopus 로고    scopus 로고
    • Dances with black widow spiders: Dysregulation of glutamate signalling enters centre stage in ADHD
    • Lesch KP, Merker S, Reif A, Novak M (2013) Dances with black widow spiders: dysregulation of glutamate signalling enters centre stage in ADHD. Eur Neuropsychopharmacol 23(6):479-491
    • (2013) Eur Neuropsychopharmacol , vol.23 , Issue.6 , pp. 479-491
    • Lesch, K.P.1    Merker, S.2    Reif, A.3    Novak, M.4
  • 104
    • 79960842090 scopus 로고    scopus 로고
    • Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis. LTP and spatial memory
    • Li H, Zhong X, Chau KF, Williams EC, Chang Q (2011) Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis. LTP and spatial memory. Nat Neurosci 14(8):1001-1008
    • (2011) Nat Neurosci , vol.14 , Issue.8 , pp. 1001-1008
    • Li, H.1    Zhong, X.2    Chau, K.F.3    Williams, E.C.4    Chang, Q.5
  • 105
    • 78349293844 scopus 로고    scopus 로고
    • The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood
    • Lichtenstein P, Carlström E, Råstam M, Gillberg C, Anckarsäter H (2010) The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood. Am J Psychiatry 167(11):1357-1363
    • (2010) Am J Psychiatry , vol.167 , Issue.11 , pp. 1357-1363
    • Lichtenstein, P.1    Carlström, E.2    Råstam, M.3    Gillberg, C.4    Anckarsäter, H.5
  • 108
    • 76849116197 scopus 로고    scopus 로고
    • Group 1 mGluR-dependent synaptic long-term depression: Mechanisms and implications for circuitry and disease
    • Lüscher C, Huber KM (2010) Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease. Neuron 65(4):445-459
    • (2010) Neuron , vol.65 , Issue.4 , pp. 445-459
    • Lüscher, C.1    Huber, K.M.2
  • 110
    • 1242317638 scopus 로고    scopus 로고
    • Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family
    • DOI 10.1007/s00424-003-1117-9, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Mackenzie B, Erickson JD (2004) Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family. Pflugers Arch 447(5):784-795 (Pubitemid 38241468)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 784-795
    • Mackenzie, B.1    Erickson, J.D.2
  • 111
  • 113
    • 24144452995 scopus 로고    scopus 로고
    • Genome-wide and ordered-subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates
    • McCauley JL, Li C, Jiang L, Olson LM, Crockett G, Gainer K, Folstein SE, Haines JL, Sutcliffe JS (2005) Genome-wide and ordered-subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates. BMC Med Genet 6:1
    • (2005) BMC Med Genet , vol.6 , pp. 1
    • McCauley, J.L.1    Li, C.2    Jiang, L.3    Olson, L.M.4    Crockett, G.5    Gainer, K.6    Folstein, S.E.7    Haines, J.L.8    Sutcliffe, J.S.9
  • 114
    • 80053929841 scopus 로고    scopus 로고
    • mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism
    • Mehta MV, Gandal MJ, Siegel SJ (2011) mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism. PLoS One 6(10):e26077
    • (2011) PLoS One , vol.6 , Issue.10
    • Mehta, M.V.1    Gandal, M.J.2    Siegel, S.J.3
  • 124
    • 84885163085 scopus 로고    scopus 로고
    • Long-term potentiation: Peeling the onion
    • Nicoll RA, Roche KW (2013) Long-term potentiation: peeling the onion. Neuropharmacology 74:18-22
    • (2013) Neuropharmacology , vol.74 , pp. 18-22
    • Nicoll, R.A.1    Roche, K.W.2
  • 130
  • 132
    • 79951855583 scopus 로고    scopus 로고
    • Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse
    • Pacey LKK, Doss L, Cifelli C, van der Kooy Derek, Heximer SP, Hampson DR (2011) Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse. Mol Cell Neurosci 46(3):563-572
    • (2011) Mol Cell Neurosci , vol.46 , Issue.3 , pp. 563-572
    • Pacey, L.K.K.1    Doss, L.2    Cifelli, C.3    Van Der Kooy, D.4    Heximer, S.P.5    Hampson, D.R.6
  • 139
    • 0033998542 scopus 로고    scopus 로고
    • Genetic evaluation of pervasive developmental disorders: The terminal 22q13 deletion syndrome may represent a recognizable phenotype
    • DOI 10.1034/j.1399-0004.2000.570203.x
    • Prasad C, Prasad AN, Chodirker BN, Lee C, Dawson AK, Jocelyn LJ, Chudley AE (2000) Genetic evaluation of pervasive developmental disorders: the terminal 22q13 deletion syndrome may represent a recognizable phenotype. Clin Genet 57(2):103-109 (Pubitemid 30116588)
    • (2000) Clinical Genetics , vol.57 , Issue.2 , pp. 103-109
    • Prasad, C.1    Prasad, A.N.2    Chodirker, B.N.3    Lee, C.4    Dawson, A.K.5    Jocelyn, L.J.6    Chudley, A.E.7
  • 140
    • 8844240684 scopus 로고    scopus 로고
    • Behavioral and cognitive aspects of tuberous sclerosis complex
    • Prather P, de Vries PJ (2004) Behavioral and cognitive aspects of tuberous sclerosis complex. J Child Neurol 19(9):666-674 (Pubitemid 39530075)
    • (2004) Journal of Child Neurology , vol.19 , Issue.9 , pp. 666-674
    • Prather, P.1    De Vries, P.J.2
  • 141
    • 2542435173 scopus 로고    scopus 로고
    • A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R
    • Ramanathan S, Woodroffe A, Flodman PL, Mays LZ, Hanouni M, Modahl CB, Steinberg-Epstein R, Bocian ME, Spence MA, Smith M (2004) A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R. BMC Med Genet 5(1):10
    • (2004) BMC Med Genet , vol.5 , Issue.1 , pp. 10
    • Ramanathan, S.1    Woodroffe, A.2    Flodman, P.L.3    Mays, L.Z.4    Hanouni, M.5    Modahl, C.B.6    Steinberg-Epstein, R.7    Bocian, M.E.8    Spence, M.A.9    Smith, M.10
  • 149
    • 78650121290 scopus 로고    scopus 로고
    • CREB: A multifaceted regulator of neuronal plasticity and protection
    • Sakamoto K, Karelina K, Obrietan K (2011) CREB: a multifaceted regulator of neuronal plasticity and protection. J Neurochem 116(1):1-9
    • (2011) J Neurochem , vol.116 , Issue.1 , pp. 1-9
    • Sakamoto, K.1    Karelina, K.2    Obrietan, K.3
  • 153
    • 3342895823 scopus 로고    scopus 로고
    • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
    • DOI 10.1016/j.cub.2004.06.054, PII S0960982204004713
    • Sarbassov DD, Ali SM, Kim D, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM (2004) Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 14(14):1296-1302 (Pubitemid 38991819)
    • (2004) Current Biology , vol.14 , Issue.14 , pp. 1296-1302
    • Dos, D.S.1    Ali, S.M.2    Kim, D.-H.3    Guertin, D.A.4    Latek, R.R.5    Erdjument-Bromage, H.6    Tempst, P.7    Sabatini, D.M.8
  • 159
    • 74949096931 scopus 로고    scopus 로고
    • Association of Y chromosome haplotypes with autism
    • Serajee FJ, Mahbubul Huq AHM (2009) Association of Y chromosome haplotypes with autism. J Child Neurol 24(10):1258-1261
    • (2009) J Child Neurol , vol.24 , Issue.10 , pp. 1258-1261
    • Serajee, F.J.1    Mahbubul Huq, A.H.M.2
  • 160
    • 0037390610 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor 8 gene at 7q31: Partial duplication and possible association with autism
    • Serajee FJ, Zhong H, Nabi R, Huq AHM (2003) The metabotropic glutamate receptor 8 gene at 7q31: partial duplication and possible association with autism. J. Med. Genet 40(4):e42
    • (2003) J. Med. Genet , vol.40 , Issue.4
    • Serajee, F.J.1    Zhong, H.2    Nabi, R.3    Huq, A.H.M.4
  • 165
    • 84892930671 scopus 로고    scopus 로고
    • Kainate receptors: Multiple roles in neuronal plasticity
    • Sihra TS, Flores G, Rodríguez-Moreno A (2013) Kainate receptors: multiple roles in neuronal plasticity. Neuroscientist 20:29-43
    • (2013) Neuroscientist , vol.20 , pp. 29-43
    • Sihra, T.S.1    Flores, G.2    Rodríguez-Moreno, A.3
  • 167
    • 79959497266 scopus 로고    scopus 로고
    • A 10.46 Mb 12p11.1-12.1 interstitial deletion coincident with a 0.19 Mb NRXN1 deletion detected by array CGH in a girl with scoliosis and autism
    • Soysal Y, Vermeesch J, Davani NA, Hekimler K, Imirzalioǧlu N (2011) A 10.46 Mb 12p11.1-12.1 interstitial deletion coincident with a 0.19 Mb NRXN1 deletion detected by array CGH in a girl with scoliosis and autism. Am J Med Genet A 155A(7):1745-1752
    • (2011) Am J Med Genet a , vol.155 A , Issue.7 , pp. 1745-1752
    • Soysal, Y.1    Vermeesch, J.2    Davani, N.A.3    Hekimler, K.4    Imirzalioǧlu, N.5
  • 170
    • 68249121116 scopus 로고    scopus 로고
    • Functions of glutamate transporters in cerebellar Purkinje cell synapses
    • Takayasu Y, Iino M, Takatsuru Y, Tanaka K, Ozawa S (2009) Functions of glutamate transporters in cerebellar Purkinje cell synapses. Acta Physiol (Oxf) 197(1):1-12
    • (2009) Acta Physiol (Oxf) , vol.197 , Issue.1 , pp. 1-12
    • Takayasu, Y.1    Iino, M.2    Takatsuru, Y.3    Tanaka, K.4    Ozawa, S.5
  • 172
    • 84856639776 scopus 로고    scopus 로고
    • Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome
    • Thomas AM, Bui N, Perkins JR, Yuva-Paylor LA, Paylor R (2012) Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome. Psychopharmacology 219(1):47-58
    • (2012) Psychopharmacology , vol.219 , Issue.1 , pp. 47-58
    • Thomas, A.M.1    Bui, N.2    Perkins, J.R.3    Yuva-Paylor, L.A.4    Paylor, R.5
  • 173
    • 68649121646 scopus 로고    scopus 로고
    • The RASopathies: Developmental syndromes of Ras/MAPK pathway dysregulation
    • Tidyman WE, Rauen KA (2009) The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation. Curr Opin Genet Dev 19(3):230-236
    • (2009) Curr Opin Genet Dev , vol.19 , Issue.3 , pp. 230-236
    • Tidyman, W.E.1    Rauen, K.A.2
  • 178
    • 0032947179 scopus 로고    scopus 로고
    • Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices
    • Vanhoutte P, Barnier JV, Guibert B, Pagè s C, Besson MJ, Hipskind RA, Caboche J (1999) Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices. Mol Cell Biol 19(1):136-146 (Pubitemid 29018416)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.1 , pp. 136-146
    • Vanhoutte, P.1    Barnier, J.-V.2    Guibert, B.3    Pages, C.4    Besson, M.-J.5    Hipskind, R.A.6    Caboche, J.7
  • 181
    • 0037322465 scopus 로고    scopus 로고
    • Signaling from cAMP/PKA to MAPK and synaptic plasticity
    • DOI 10.1385/MN:27:1:99
    • Waltereit R, Weller M (2003) Signaling from cAMP/PKA to MAPK and synaptic plasticity. Mol Neurobiol 27(1):99-106 (Pubitemid 36515162)
    • (2003) Molecular Neurobiology , vol.27 , Issue.1 , pp. 99-106
    • Waltereit, R.1    Weller, M.2
  • 183
    • 0034944526 scopus 로고    scopus 로고
    • Chromosomal abnormalities in a clinic sample of individuals with autistic disorder
    • DOI 10.1097/00041444-200106000-00001
    • Wassink TH, Piven J, Patil SR (2001) Chromosomal abnormalities in a clinic sample of individuals with autistic disorder. Psychiatr Genet 11(2):57-63 (Pubitemid 32686183)
    • (2001) Psychiatric Genetics , vol.11 , Issue.2 , pp. 57-63
    • Wassink, T.H.1    Piven, J.2    Patil, S.R.3
  • 185
    • 80455177363 scopus 로고    scopus 로고
    • The prevalence puzzle: Autism counts
    • Weintraub K (2011) The prevalence puzzle: autism counts. Nature 479(7371):22-24
    • (2011) Nature , vol.479 , Issue.7371 , pp. 22-24
    • Weintraub, K.1
  • 191
    • 84862224852 scopus 로고    scopus 로고
    • AutismKB: An evidence-based knowledgebase of autism genetics
    • Xu L, Li J, Huang Y, Zhao M, Tang X, Wei L (2011) AutismKB: an evidence-based knowledgebase of autism genetics. Nucleic Acids Res 40(D1):D1016-D1022
    • (2011) Nucleic Acids Res , vol.40 , Issue.D1
    • Xu, L.1    Li, J.2    Huang, Y.3    Zhao, M.4    Tang, X.5    Wei, L.6
  • 194
    • 84862807515 scopus 로고    scopus 로고
    • Family based association of GRIN2A and GRIN2B with Korean autism spectrum disorders
    • Yoo HJ, Cho IH, Park M, Yang SY, Kim SA (2012) Family based association of GRIN2A and GRIN2B with Korean autism spectrum disorders. Neurosci Lett 512(2):89-93
    • (2012) Neurosci Lett , vol.512 , Issue.2 , pp. 89-93
    • Yoo, H.J.1    Cho, I.H.2    Park, M.3    Yang, S.Y.4    Kim, S.A.5
  • 197
    • 84866252444 scopus 로고    scopus 로고
    • MeCP2 phosphorylation is required for modulating synaptic scaling through mGluR5
    • Zhong X, Li H, Chang Q (2012) MeCP2 phosphorylation is required for modulating synaptic scaling through mGluR5. J Neurosci 32(37):12841-12847
    • (2012) J Neurosci , vol.32 , Issue.37 , pp. 12841-12847
    • Zhong, X.1    Li, H.2    Chang, Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.