A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders

Journal of Child and Adolescent Psychopharmacology

Volumn 16, Issue 5, 2006, Pages 517-524

  Owley, Thomas ^a   Salt, Jeff ^a   Guter, Stephen ^a   Grieve, Adam ^a   Walton, Laura ^a   Ayuyao, Nelson ^a   Leventhal, Bennett L ^a   Cook Jr , Edwin H ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMANTINE;

ABERRANT BEHAVIOR CHECKLIST; ARTICLE; AUTISM; BEHAVIOR DISORDER; CHILD; CHILDRENS MEMORY SCALE DOT LEARNING SUBTEST; CLINICAL ARTICLE; CLINICAL GLOBAL IMPRESSION SCALE; CLINICAL TRIAL; COGNITIVE DEFECT; DRUG EFFICACY; DRUG SAFETY; HUMAN; HYPERACTIVITY; INTELLIGENCE QUOTIENT; MALE; MEMORY DISORDER; OPEN STUDY; RATING SCALE;

CHILD; CHILD BEHAVIOR DISORDERS; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CHILD, PRESCHOOL; COGNITION DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLUTAMIC ACID; HUMANS; INTELLIGENCE; LANGUAGE DEVELOPMENT DISORDERS; MALE; MEMANTINE; MEMORY DISORDERS; NEUROPSYCHOLOGICAL TESTS; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 33750950870     PISSN: 10445463     EISSN: None     Source Type: Journal    
DOI: 10.1089/cap.2006.16.517     Document Type: Article

References (22)

1. Aman MG, Singh NN, Stewart AW, Field CJ: The Aberrant Behavior Checklist: A behavior rating scale for the assessment of treatment effects. Am J Ment Def 39:485-491, 1985.
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV). Washington, DC, American Psychiatric Association, 1994.
3. Blue M, Naidu S, Johnston M: Altered development of glutamate and GABA receptors in the basal ganglia of girls with Rett Syndrome. Exp Neurol 156:345-352, 1999.
4. Carlsson M: Hypothesis: Is infantile autism a hypoglutamatergic disorder? Relevance of glutamate-serotonin interactions for pharmacotherapy. J Neural Transm 105:525-535, 1998.
5. Chakrabarti S, Fombonne E: Pervasive developmental disorders in preschool children: Confirmation of high prevalence. Am J Psych 162: 1133-1141, 2005.
6. Cohen, MJ: Children's Memory Scale. San Antonio, TX, The Psychological Corporation, 1997.
7. Dunn LM, Dunn LM: Peabody Picture Vocabulary Test-III. American Guidance Service, LTD, 1997.
8. Elliott CD: Differential Abilities Scale-Preschool. San Antonio, TX, The Psychological Corporation, 1990.
9. Gardner MF: Expressive One Word Picture Vocabulary Test. Academic Therapy Publications, Novato, CA, 1990.
10. Guy W (ed): ECDEU Assessment Manual for Psychopharmacology, Revised. Rockville, MD, U.S. Department of Health and Human Service, Alcohol Drug Abuse and Mental Health Administration, NIMH Psychopharmacology Research Branch, 1976.
11. Kemp JA, McKernan RM: NMDA receptor pathways as drug targets. Nat Neurosci Nov(Suppl 5):1039-1042, 2002.
12. Kemper T, Bauman M: The contribution of neuropathologic studies to the understanding of autism. Neurol. Clin. 11:175-187, 1993.
13. King BH, Wright DM, Snape M, Dourish CT: Case series: Amantadine open-label treatment of aggressive behavior in hospitalized children with developmental disabilities. J Am Acad Child Adolesc Psychiatry 40:654-657, 2001a.
14. King BH, Wright DM, Handen BL, Sikich L, Zimmerman AW, McMahon W, Cantwell E, Davanzo PA, Dourish CT, Dykens EM, Hooper SR, Jaselskis CA, Leventhal BL, Levitt J, Lord C, Lubetsky MJ, Myers SM, Ozonoff S, Shah BG, Snape M, Shernoff EW, Williamson K, Cook EH, Jr: Double-blind, placebo-controlled trial of amantadine hydrochloride in the treatment of children with autistic disorder. J Am Acad Child Adolesc Psychiatry 40:658-665, 2001b.
15. Lappalainen R, Riikonen R: High levels of cerebrospinal fluid in Rett Syndrome. Pediatr Neurol 15:213-216, 1996.
16. Lord C, Rutter M, Le Couteur A: Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev. Disord 24:659-685, 1994.
17. Lord C, Risi S, Lambrecht L, Cook EH, Jr, Leventhal BL, DiLavore PC, Pickles A, Rutter M: The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord 30:205-223, 2000.
18. McDonald J, Johnston M, Young A: Differential ontogenic development of three receptors comprising the NMDA receptor/channel complex in the rat hippocampus. Exp Neurol 110:237-247, 1990.
19. Mullen E: Mullen Scales of Early Learning. Cranston, RI, T.O.T.A.L. Child.
20. Pan J, Lane J, Hetherington H, Percy A: Rett Syndrome: 1H spectroscopic imaging at 4.1 Tesla. J Child Neurol 14:524-528, 1999.
21. Raven JC, Court JH, Raven J: Manual for Raven's progressive matrices and vocabulary scales. London, H.K. Lewis, 1983.
22. Reisberg B, Doody R, Stoffler A, Schmitt F, Ferris S, Mobius HJ: Memantine in moderate-to-severe Alzheimer's disease. N Engl J Med 348:1333-1341, 2003.