Group i metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome

Psychopharmacology

Volumn 219, Issue 1, 2012, Pages 47-58

  Thomas, Alexia M ^a   Bui, Nghiem ^a   Perkins, Jennifer R ^a   Yuva Paylor, Lisa A ^a   Paylor, Richard ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Behavior; Fmr1; Fragile X; Metabotropic glutamate receptor; Mouse

Indexed keywords

(3,4 DIHYDRO 2H PYRANO[2,3]B QUINOLIN 7 YL) (4 METHOXYCYCLOHEXYL)METHANONE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; FRAGILE X MENTAL RETARDATION PROTEIN; JNJ 16259685; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDIOGENIC SEIZURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; FEMALE; FRAGILE X SYNDROME; MALE; MOTOR COORDINATION; MOTOR PERFORMANCE; MOUSE; NONHUMAN; OPEN FIELD TEST; PREPULSE INHIBITION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RECEPTOR BLOCKING; ROTAROD TEST; SIGNAL TRANSDUCTION; WILD TYPE;

ACOUSTIC STIMULATION; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; QUINOLINES; RECEPTORS, METABOTROPIC GLUTAMATE; STARTLE REACTION;

EID: 84856639776     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-011-2375-4     Document Type: Article

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