메뉴 건너뛰기




Volumn 447, Issue 5, 2004, Pages 784-795

Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family

Author keywords

Adaptive regulation; Amino acid transport; Ammonia detoxification; Gluconeogenesis; Glutamate glutamine cycle; Glutamine transport; SNAT6

Indexed keywords

AMMONIA; COTRANSPORTER; GLUTAMINE; PROTEIN SUBUNIT; SOCIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 4; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 1; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 2; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 3; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 5; UNCLASSIFIED DRUG;

EID: 1242317638     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-003-1117-9     Document Type: Review
Times cited : (430)

References (100)
  • 1
    • 0025168270 scopus 로고
    • Characteristics of glutamine transport in sarcolemmal vesicles from rat skeletal muscle
    • Ahmed A, Taylor PM, Rennie MJ (1990) Characteristics of glutamine transport in sarcolemmal vesicles from rat skeletal muscle. Am J Physiol 259:E284-E291
    • (1990) Am J Physiol , vol.259
    • Ahmed, A.1    Taylor, P.M.2    Rennie, M.J.3
  • 5
    • 0036790040 scopus 로고    scopus 로고
    • The mechanism for transcriptional activation of the human ATA2 transporter gene by amino acid deprivation is different than that for asparagine synthetase
    • Bain PJ, LeBlanc-Chaffin R, Chen H, Palii SS, Leach KM, Kilberg MS (2002) The mechanism for transcriptional activation of the human ATA2 transporter gene by amino acid deprivation is different than that for asparagine synthetase. J Nutr 132:3023-3029
    • (2002) J Nutr , vol.132 , pp. 3023-3029
    • Bain, P.J.1    LeBlanc-Chaffin, R.2    Chen, H.3    Palii, S.S.4    Leach, K.M.5    Kilberg, M.S.6
  • 6
    • 0033770994 scopus 로고    scopus 로고
    • Hypoxia inhibits amino acid uptake in human lung fibroblasts
    • Berk JL, Hatch CA, Goldstein RH (2000) Hypoxia inhibits amino acid uptake in human lung fibroblasts. J Appl Physiol 89:1425-1431
    • (2000) J Appl Physiol , vol.89 , pp. 1425-1431
    • Berk, J.L.1    Hatch, C.A.2    Goldstein, R.H.3
  • 7
    • 0036514241 scopus 로고    scopus 로고
    • Role of estrogen receptor in the regulation of estrogen induced amino acid transport of System A in breast cancer and other receptor positive tumor cells
    • Bhat HK, Vadgama JV (2002) Role of estrogen receptor in the regulation of estrogen induced amino acid transport of System A in breast cancer and other receptor positive tumor cells. Int J Mol Med 9:271-279
    • (2002) Int J Mol Med , vol.9 , pp. 271-279
    • Bhat, H.K.1    Vadgama, J.V.2
  • 9
    • 0037325253 scopus 로고    scopus 로고
    • Highly differential expression of SN1, a bidirectional glutamine transporter, in astroglia and endothelium in the developing rat brain
    • Boulland J-L, Rafiki A, Levy LM, Storm-Mathisen J, Chaudhry FA (2003) Highly differential expression of SN1, a bidirectional glutamine transporter, in astroglia and endothelium in the developing rat brain. Glia 41:260-275
    • (2003) Glia , vol.41 , pp. 260-275
    • Boulland, J.-L.1    Rafiki, A.2    Levy, L.M.3    Storm-Mathisen, J.4    Chaudhry, F.A.5
  • 10
    • 0017062943 scopus 로고
    • On glutaminase activity in mammalian synaptosomes
    • Bradford HF, Ward HK (1976) On glutaminase activity in mammalian synaptosomes. Brain Res 110:115-125
    • (1976) Brain Res , vol.110 , pp. 115-125
    • Bradford, H.F.1    Ward, H.K.2
  • 13
    • 0038469628 scopus 로고    scopus 로고
    • Transfer of glutamine between astrocytes and neurons
    • Bröer S, Brookes N (2001) Transfer of glutamine between astrocytes and neurons. J Neurochem 77:705-719
    • (2001) J Neurochem , vol.77 , pp. 705-719
    • Bröer, S.1    Brookes, N.2
  • 14
    • 0027444554 scopus 로고
    • Extracellular potassium regulates the glutamine content of astrocytes: Mediation by intracellular pH
    • Brookes N, Turner RJ (1993) Extracellular potassium regulates the glutamine content of astrocytes: mediation by intracellular pH. Neurosci Lett 160:73-76
    • (1993) Neurosci Lett , vol.160 , pp. 73-76
    • Brookes, N.1    Turner, R.J.2
  • 15
    • 0033598956 scopus 로고    scopus 로고
    • Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission
    • Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH (1999) Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission. Cell 99:769-780
    • (1999) Cell , vol.99 , pp. 769-780
    • Chaudhry, F.A.1    Reimer, R.J.2    Krizaj, D.3    Barber, D.4    Storm-Mathisen, J.5    Copenhagen, D.R.6    Edwards, R.H.7
  • 18
    • 0034635597 scopus 로고    scopus 로고
    • Dietary protein content affects the profiles of extracellular amino acids in the medial preoptic area of freely moving rats
    • Choi YH, Chang N, Fletcher PJ, Anderson GH (2000) Dietary protein content affects the profiles of extracellular amino acids in the medial preoptic area of freely moving rats. Life Sci 66:1105-1118
    • (2000) Life Sci , vol.66 , pp. 1105-1118
    • Choi, Y.H.1    Chang, N.2    Fletcher, P.J.3    Anderson, G.H.4
  • 19
    • 1242312642 scopus 로고
    • Distribution of amino acids between cellular and extracellular fluids. Relation to growth
    • Christensen HN (1948) Distribution of amino acids between cellular and extracellular fluids. Relation to growth. Bull N Engl Med Ctr 10:108-111
    • (1948) Bull N Engl Med Ctr , vol.10 , pp. 108-111
    • Christensen, H.N.1
  • 20
    • 0020201899 scopus 로고
    • Interorgan amino acid nutrition
    • Christensen HN (1982) Interorgan amino acid nutrition. Physiol Rev 62:1193-1233
    • (1982) Physiol Rev , vol.62 , pp. 1193-1233
    • Christensen, H.N.1
  • 21
    • 0025095302 scopus 로고
    • Role of amino acid transport and countertransport in nutrition and metabolism
    • Christensen HN (1990) Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev 70:43-77
    • (1990) Physiol Rev , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 22
    • 0017709068 scopus 로고
    • + selectivity in transport System A: Effects of substrate structure
    • + selectivity in transport System A: effects of substrate structure. J Membr Biol 37:193-211
    • (1977) J Membr Biol , vol.37 , pp. 193-211
    • Christensen, H.N.1    Handlogten, M.E.2
  • 23
    • 0001594597 scopus 로고
    • The use of N-methylation to direct the route of mediated transport of amino acids
    • Christensen HN, Oxender DL, Liang M, Vatz KA (1965) The use of N-methylation to direct the route of mediated transport of amino acids. J Biol Chem 240:3609-3616
    • (1965) J Biol Chem , vol.240 , pp. 3609-3616
    • Christensen, H.N.1    Oxender, D.L.2    Liang, M.3    Vatz, K.A.4
  • 24
    • 0028310347 scopus 로고
    • Glutamate immunoreactivity in rat cerebral cortex is reversibly abolished by 6-diazo-5-oxo-L-norleucine (DON), an inhibitor of phosphate-activated glutaminase
    • Conti F, Minelli A (1994) Glutamate immunoreactivity in rat cerebral cortex is reversibly abolished by 6-diazo-5-oxo-L-norleucine (DON), an inhibitor of phosphate-activated glutaminase. J Histochem Cytochem 42:717-726
    • (1994) J Histochem Cytochem , vol.42 , pp. 717-726
    • Conti, F.1    Minelli, A.2
  • 25
    • 0035626836 scopus 로고    scopus 로고
    • Transforming growth factor-β 1 stimulates vascular smooth muscle cell L-proline transport by inducing system A amino acid transporter 2 (SAT2) gene expression
    • Ensenat D, Hassan S, Reyna SV, Schafer AI, Durante W (2001) Transforming growth factor-β 1 stimulates vascular smooth muscle cell L-proline transport by inducing system A amino acid transporter 2 (SAT2) gene expression. Biochem J 360:507-512
    • (2001) Biochem J , vol.360 , pp. 507-512
    • Ensenat, D.1    Hassan, S.2    Reyna, S.V.3    Schafer, A.I.4    Durante, W.5
  • 26
    • 0028343853 scopus 로고
    • Cerebral alanine transport and alanine aminotransferase reaction: Alanine as a source of neuronal glutamate
    • Erecińska M, Nelson D, Nissim I, Daikhin Y, Yudkoff M (1994) Cerebral alanine transport and alanine aminotransferase reaction: alanine as a source of neuronal glutamate. J Neurochem 62:1953-1964
    • (1994) J Neurochem , vol.62 , pp. 1953-1964
    • Erecińska, M.1    Nelson, D.2    Nissim, I.3    Daikhin, Y.4    Yudkoff, M.5
  • 29
    • 0034724370 scopus 로고    scopus 로고
    • Identification and characterization of an amino acid transporter expressed differentially in liver
    • Gu S, Roderick HL, Camacho P, Jiang JX (2000) Identification and characterization of an amino acid transporter expressed differentially in liver. Proc Natl Acad Sci USA 97:3230-3235
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3230-3235
    • Gu, S.1    Roderick, H.L.2    Camacho, P.3    Jiang, J.X.4
  • 30
    • 0035874932 scopus 로고    scopus 로고
    • A novel human amino acid transporter, hNAT3: cDNA cloning, chromosomal mapping, genomic structure, expression, and functional characterization
    • Gu S, Adan-Rice D, Leach RJ, Jiang JX (2001) A novel human amino acid transporter, hNAT3: cDNA cloning, chromosomal mapping, genomic structure, expression, and functional characterization. Genomics 74:262-272
    • (2001) Genomics , vol.74 , pp. 262-272
    • Gu, S.1    Adan-Rice, D.2    Leach, R.J.3    Jiang, J.X.4
  • 31
    • 0035968337 scopus 로고    scopus 로고
    • Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport
    • Gu S, Roderick HL, Camacho P, Jiang JX (2001) Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport. J Biol Chem 276:24137-24144
    • (2001) J Biol Chem , vol.276 , pp. 24137-24144
    • Gu, S.1    Roderick, H.L.2    Camacho, P.3    Jiang, J.X.4
  • 32
    • 0037908675 scopus 로고    scopus 로고
    • Mouse system-N amino acid transporter, mNAT3, expressed in hepatocytes and regulated by insulin-activated and phosphoinositide 3-kinase-dependent signalling
    • Gu S, Langlais P, Liu F, Jiang JX (2003) Mouse system-N amino acid transporter, mNAT3, expressed in hepatocytes and regulated by insulin-activated and phosphoinositide 3-kinase-dependent signalling. Biochem J 371:721-731
    • (2003) Biochem J , vol.371 , pp. 721-731
    • Gu, S.1    Langlais, P.2    Liu, F.3    Jiang, J.X.4
  • 33
    • 0023778738 scopus 로고
    • Insulin-stimulated α-(methyl)aminoisobutyric acid uptake in skeletal muscle
    • Gumà A, Testar X, Palacín M, Zorzano A (1988) Insulin-stimulated α-(methyl)aminoisobutyric acid uptake in skeletal muscle. Biochem J 253:625-629
    • (1988) Biochem J , vol.253 , pp. 625-629
    • Gumà, A.1    Testar, X.2    Palacín, M.3    Zorzano, A.4
  • 34
    • 0018392519 scopus 로고
    • Glutamate as a CNS transmitter. I. Evaluation of glucose and glutamine as precursors for the synthesis of preferentially released glutamate
    • Hamberger AC, Chiang GH, Nylen ES, Scheff SW, Cotman CW (1979) Glutamate as a CNS transmitter. I. Evaluation of glucose and glutamine as precursors for the synthesis of preferentially released glutamate. Brain Res 168:513-530
    • (1979) Brain Res , vol.168 , pp. 513-530
    • Hamberger, A.C.1    Chiang, G.H.2    Nylen, E.S.3    Scheff, S.W.4    Cotman, C.W.5
  • 35
    • 0034738568 scopus 로고    scopus 로고
    • Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A
    • Hatanaka T, Huang W, Wang H, Sugawara M, Prasad PD, Leibach FH, Ganapathy V (2000) Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A. Biochim Biophys Acta 1467:1-6
    • (2000) Biochim Biophys Acta , vol.1467 , pp. 1-6
    • Hatanaka, T.1    Huang, W.2    Wang, H.3    Sugawara, M.4    Prasad, P.D.5    Leibach, F.H.6    Ganapathy, V.7
  • 36
    • 0035860406 scopus 로고    scopus 로고
    • Differential influence of cAMP on the expression of the three subtypes (ATA1, ATA2, and ATA3) of the amino acid transport system A
    • Hatanaka T, Huang W, Martindale RG, Ganapathy V (2001) Differential influence of cAMP on the expression of the three subtypes (ATA1, ATA2, and ATA3) of the amino acid transport system A. FEBS Lett 505:317-320
    • (2001) FEBS Lett , vol.505 , pp. 317-320
    • Hatanaka, T.1    Huang, W.2    Martindale, R.G.3    Ganapathy, V.4
  • 37
    • 0035830588 scopus 로고    scopus 로고
    • Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A
    • Hatanaka T, Huang W, Ling R, Prasad PD, Sugawara M, Leibach FH, Ganapathy V (2001) Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A. Biochim Biophys Acta 1510:10-17
    • (2001) Biochim Biophys Acta , vol.1510 , pp. 10-17
    • Hatanaka, T.1    Huang, W.2    Ling, R.3    Prasad, P.D.4    Sugawara, M.5    Leibach, F.H.6    Ganapathy, V.7
  • 38
    • 0025231570 scopus 로고
    • Nitrogen metabolism in liver: Structural and functional organization and physiological relevance
    • Häussinger D (1990) Nitrogen metabolism in liver: structural and functional organization and physiological relevance. Biochem J 267:281-290
    • (1990) Biochem J , vol.267 , pp. 281-290
    • Häussinger, D.1
  • 39
    • 0002868933 scopus 로고
    • Amino acid transport, cell volume and regulation of cell growth
    • Kilberg MS, Häussinger D (eds) Plenum Press, New York
    • Häussinger D, Lang F, Kilberg MS (1992) Amino acid transport, cell volume and regulation of cell growth. In: Kilberg MS, Häussinger D (eds) Mammalian amino acid transport: mechanisms and control. Plenum Press, New York, pp 113-130
    • (1992) Mammalian Amino Acid Transport: Mechanisms and Control , pp. 113-130
    • Häussinger, D.1    Lang, F.2    Kilberg, M.S.3
  • 42
    • 0030867766 scopus 로고    scopus 로고
    • From receptor to transporter: Insulin signalling to glucose transport
    • Holman GD, Kasuga M (1997) From receptor to transporter: insulin signalling to glucose transport. Diabetogia 40:991-1003
    • (1997) Diabetogia , vol.40 , pp. 991-1003
    • Holman, G.D.1    Kasuga, M.2
  • 43
    • 0023571527 scopus 로고
    • Characteristics of L-glutamine transport in perfused rat skeletal muscle
    • Lond
    • Hundal HS, Rennie MJ, Watt PW (1987) Characteristics of L-glutamine transport in perfused rat skeletal muscle. J Physiol (Lond) 393:283-305
    • (1987) J Physiol , vol.393 , pp. 283-305
    • Hundal, H.S.1    Rennie, M.J.2    Watt, P.W.3
  • 44
    • 0035340912 scopus 로고    scopus 로고
    • Subcellular localization and adaptive upregulation of the System A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes
    • Hyde R, Christie GR, Litherland GJ, Hajduch E, Taylor PM, Hundal HS (2001) Subcellular localization and adaptive upregulation of the System A (SAT2) amino acid transporter in skeletal-muscle cells and adipocytes. Biochem J 355:563-568
    • (2001) Biochem J , vol.355 , pp. 563-568
    • Hyde, R.1    Christie, G.R.2    Litherland, G.J.3    Hajduch, E.4    Taylor, P.M.5    Hundal, H.S.6
  • 45
    • 0037134492 scopus 로고    scopus 로고
    • Insulin promotes the cell surface recruitment of the SAT2/ATA2 System A amino acid transporter from an endosomal compartment in skeletal muscles cells
    • Hyde R, Peyrollier K, Hundal HS (2002) Insulin promotes the cell surface recruitment of the SAT2/ATA2 System A amino acid transporter from an endosomal compartment in skeletal muscles cells. J Biol Chem 277:13628-13634
    • (2002) J Biol Chem , vol.277 , pp. 13628-13634
    • Hyde, R.1    Peyrollier, K.2    Hundal, H.S.3
  • 46
    • 0023003560 scopus 로고
    • Characterization of glutamine transport by liver plasma membrane vesicles
    • Jacob R, Rosenthal N, Barrett EJ (1986) Characterization of glutamine transport by liver plasma membrane vesicles. Am J Physiol 251:E509-E514
    • (1986) Am J Physiol , vol.251
    • Jacob, R.1    Rosenthal, N.2    Barrett, E.J.3
  • 48
    • 0036838665 scopus 로고    scopus 로고
    • Regulation of expression of the SN1 transporter during renal adaptation to chronic metabolic acidosis in rats
    • Karinch AM, Lin C-M, Wolfgang CL, Pan M, Souba WW (2002) Regulation of expression of the SN1 transporter during renal adaptation to chronic metabolic acidosis in rats. Am J Physiol 283:F1011-F1019
    • (2002) Am J Physiol , vol.283
    • Karinch, A.M.1    Lin, C.-M.2    Wolfgang, C.L.3    Pan, M.4    Souba, W.W.5
  • 51
    • 0019195152 scopus 로고
    • Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs
    • Kilberg MS, Handlogten ME, Christensen HN (1980) Characteristics of an amino acid transport system in rat liver for glutamine, asparagine, histidine, and closely related analogs. J Biol Chem 255:4011-4019
    • (1980) J Biol Chem , vol.255 , pp. 4011-4019
    • Kilberg, M.S.1    Handlogten, M.E.2    Christensen, H.N.3
  • 52
    • 0021993469 scopus 로고
    • Adaptive regulation of neutral amino acid transport System A in rat H4 hepatoma cells
    • Kilberg MS, Han HP, Barber EF, Chiles TC (1985) Adaptive regulation of neutral amino acid transport System A in rat H4 hepatoma cells. J Cell Physiol 122:290-298
    • (1985) J Cell Physiol , vol.122 , pp. 290-298
    • Kilberg, M.S.1    Han, H.P.2    Barber, E.F.3    Chiles, T.C.4
  • 53
    • 0029091514 scopus 로고
    • Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: Immunogold evidence from hippocampal slice cultures
    • Laake JH, Slyngstad TA, Haug FM, Ottersen OP (1995) Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice cultures. J Neurochem 65:871-881
    • (1995) J Neurochem , vol.65 , pp. 871-881
    • Laake, J.H.1    Slyngstad, T.A.2    Haug, F.M.3    Ottersen, O.P.4
  • 54
    • 0035795723 scopus 로고    scopus 로고
    • Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A
    • Ling R, Bridges CC, Sugawara M, Fujita T, Leibach FH, Prasad PD, Ganapathy V (2001) Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A. Biochim Biophys Acta 1512:15-21
    • (2001) Biochim Biophys Acta , vol.1512 , pp. 15-21
    • Ling, R.1    Bridges, C.C.2    Sugawara, M.3    Fujita, T.4    Leibach, F.H.5    Prasad, P.D.6    Ganapathy, V.7
  • 55
    • 0025862316 scopus 로고
    • Substrate-specificity of glutamine transporters in membrane vesicles from rat liver and skeletal muscle investigated using amino acid analogues
    • Low SY, Taylor PM, Ahmed A, Pogson CI, Rennie MJ (1991) Substrate-specificity of glutamine transporters in membrane vesicles from rat liver and skeletal muscle investigated using amino acid analogues. Biochem J 278:105-111
    • (1991) Biochem J , vol.278 , pp. 105-111
    • Low, S.Y.1    Taylor, P.M.2    Ahmed, A.3    Pogson, C.I.4    Rennie, M.J.5
  • 56
    • 0019221160 scopus 로고
    • Glutamine metabolism in the rat
    • Lund P (1980) Glutamine metabolism in the rat. FEBS Lett 117 (Suppl):K86-K92
    • (1980) FEBS Lett , vol.117 , Issue.SUPPL.
    • Lund, P.1
  • 58
    • 0037930294 scopus 로고    scopus 로고
    • Functional properties and cellular distribution of the System A glutamine transporter SNAT1 support specialized roles in central neurons
    • Mackenzie B, Schäfer MKH, Erickson JD, Hediger MA, Weihe E, Varoqui H (2003) Functional properties and cellular distribution of the System A glutamine transporter SNAT1 support specialized roles in central neurons. J Biol Chem 278:23720-23730
    • (2003) J Biol Chem , vol.278 , pp. 23720-23730
    • Mackenzie, B.1    Schäfer, M.K.H.2    Erickson, J.D.3    Hediger, M.A.4    Weihe, E.5    Varoqui, H.6
  • 59
    • 25744456668 scopus 로고    scopus 로고
    • Functional properties of the neuronal System A glutamine transporter (SAT1) and identification of a critical histidyl residue
    • Mackenzie B, Yao D, Erickson JD, Hediger MA, Varoqui H (2003) Functional properties of the neuronal System A glutamine transporter (SAT1) and identification of a critical histidyl residue (abstract). FASEB J 17:A906
    • (2003) FASEB J , vol.17
    • Mackenzie, B.1    Yao, D.2    Erickson, J.D.3    Hediger, M.A.4    Varoqui, H.5
  • 60
    • 0027458062 scopus 로고
    • Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies
    • Mahendran D, Donnai P, Glazier JD, D'Souza SW, Boyd RDH, Sibley CP (1993) Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies. Pediatr Res 34:661-665
    • (1993) Pediatr Res , vol.34 , pp. 661-665
    • Mahendran, D.1    Donnai, P.2    Glazier, J.D.3    D'Souza, S.W.4    Boyd, R.D.H.5    Sibley, C.P.6
  • 63
    • 0028205533 scopus 로고
    • Regulatory and molecular aspects of mammalian amino acid transport
    • McGivan JD, Pastor-Anglada M (1994) Regulatory and molecular aspects of mammalian amino acid transport. Biochem J 299:321-334
    • (1994) Biochem J , vol.299 , pp. 321-334
    • McGivan, J.D.1    Pastor-Anglada, M.2
  • 65
    • 13044250453 scopus 로고    scopus 로고
    • Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity
    • Miyakawa H, Woo SK, Dahl SC, Handler JS, Kwon HM (1999) Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity. Proc Natl Acad Sci USA 96:2538-2542
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2538-2542
    • Miyakawa, H.1    Woo, S.K.2    Dahl, S.C.3    Handler, J.S.4    Kwon, H.M.5
  • 66
    • 0030005938 scopus 로고    scopus 로고
    • Glutamine transport in mouse cerebral astrocytes
    • Nagaraja TN, Brookes N (1996) Glutamine transport in mouse cerebral astrocytes. J Neurochem 66:1665-1674
    • (1996) J Neurochem , vol.66 , pp. 1665-1674
    • Nagaraja, T.N.1    Brookes, N.2
  • 67
    • 0036079677 scopus 로고    scopus 로고
    • Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity
    • Nahm O, Woo SK, Handler JS, Kwon HM (2002) Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity. Am J Physiol 282:C49-C58
    • (2002) Am J Physiol , vol.282
    • Nahm, O.1    Woo, S.K.2    Handler, J.S.3    Kwon, H.M.4
  • 72
    • 78651131107 scopus 로고
    • Distinct mediating systems for the transport of neutral amino acids by the Ehrlich cell
    • Oxender DL, Christensen HN (1963) Distinct mediating systems for the transport of neutral amino acids by the Ehrlich cell. J Biol Chem 238:3686-3699
    • (1963) J Biol Chem , vol.238 , pp. 3686-3699
    • Oxender, D.L.1    Christensen, H.N.2
  • 73
    • 0030203863 scopus 로고    scopus 로고
    • TreeView: An application to display phylogenetic trees on personal computers
    • Page RDM (1996) TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12:357-358
    • (1996) Comput Appl Biosci , vol.12 , pp. 357-358
    • Page, R.D.M.1
  • 74
    • 0035167923 scopus 로고    scopus 로고
    • Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex
    • Phillis JW, Ren J, O'Regan MH (2001) Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex. J Neurochem 76:247-257
    • (2001) J Neurochem , vol.76 , pp. 247-257
    • Phillis, J.W.1    Ren, J.2    O'Regan, M.H.3
  • 75
    • 0028360382 scopus 로고
    • Glutamate in some retinal neurons is derived solely from glia
    • Pow DV, Robinson SR (1994) Glutamate in some retinal neurons is derived solely from glia. Neuroscience 60:355-366
    • (1994) Neuroscience , vol.60 , pp. 355-366
    • Pow, D.V.1    Robinson, S.R.2
  • 76
    • 0034608866 scopus 로고    scopus 로고
    • Amino acid transport system A resembles system N in sequence but differs in mechanism
    • Reimer RJ, Chaudhry FA, Gray AT, Edwards RH (2000) Amino acid transport system A resembles system N in sequence but differs in mechanism. Proc Natl Acad Sci USA 97:7715-7720
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7715-7720
    • Reimer, R.J.1    Chaudhry, F.A.2    Gray, A.T.3    Edwards, R.H.4
  • 77
    • 0034847452 scopus 로고    scopus 로고
    • Interaction between glutamine availability and metabolism of glycogen, tricarboxylic acid cycle intermediates and glutathione
    • Rennie MJ, Bowtell JL, Brace M, Khogali SEO (2001) Interaction between glutamine availability and metabolism of glycogen, tricarboxylic acid cycle intermediates and glutathione. J Nutr 131:2488S-2490S
    • (2001) J Nutr , vol.131
    • Rennie, M.J.1    Bowtell, J.L.2    Brace, M.3    Khogali, S.E.O.4
  • 78
    • 0038650885 scopus 로고    scopus 로고
    • In vivo NMR studies of the neurotransmitter flux and neuroenergetics: Implications for brain function
    • Rothman DL, Behar KL, Hyder F, Shulman RG (2003) In vivo NMR studies of the neurotransmitter flux and neuroenergetics: implications for brain function. Annu Rev Physiol 65:401-427
    • (2003) Annu Rev Physiol , vol.65 , pp. 401-427
    • Rothman, D.L.1    Behar, K.L.2    Hyder, F.3    Shulman, R.G.4
  • 79
    • 0035968245 scopus 로고    scopus 로고
    • A family of yeast proteins mediating bidirectional vacuolar amino acid transport
    • Russnak R, Konczal D, McIntire SL (2001) A family of yeast proteins mediating bidirectional vacuolar amino acid transport. J Biol Chem 276:23849-23857
    • (2001) J Biol Chem , vol.276 , pp. 23849-23857
    • Russnak, R.1    Konczal, D.2    McIntire, S.L.3
  • 81
    • 0023748079 scopus 로고
    • Neutral amino acid transport systems in animal cells: Potential targets of oncogene action and regulators of cellular growth
    • Saier MH, Daniels GA, Boerner P, Lin J (1988) Neutral amino acid transport systems in animal cells: potential targets of oncogene action and regulators of cellular growth. J Membr Biol 104:1-20
    • (1988) J Membr Biol , vol.104 , pp. 1-20
    • Saier, M.H.1    Daniels, G.A.2    Boerner, P.3    Lin, J.4
  • 82
    • 0019796746 scopus 로고
    • Neutral amino acid transport systems in Chinese hamster ovary cells
    • Shotwell MA, Jayme DW, Kilberg MS, Oxender DL (1981) Neutral amino acid transport systems in Chinese hamster ovary cells. J Biol Chem 256:5422-5427
    • (1981) J Biol Chem , vol.256 , pp. 5422-5427
    • Shotwell, M.A.1    Jayme, D.W.2    Kilberg, M.S.3    Oxender, D.L.4
  • 84
    • 0030952190 scopus 로고    scopus 로고
    • Glutamine transport in cerebellar granule cells in culture
    • Su TZ, Campbell GW, Oxender DL (1997) Glutamine transport in cerebellar granule cells in culture. Brain Res 757:69-78
    • (1997) Brain Res , vol.757 , pp. 69-78
    • Su, T.Z.1    Campbell, G.W.2    Oxender, D.L.3
  • 85
    • 0034595870 scopus 로고    scopus 로고
    • Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of System A
    • Sugawara M, Nakanishi T, Fei YJ, Huang W, Ganapathy ME, Leibach FH, Ganapathy V (2000) Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of System A. J Biol Chem 275:16473-16477
    • (2000) J Biol Chem , vol.275 , pp. 16473-16477
    • Sugawara, M.1    Nakanishi, T.2    Fei, Y.J.3    Huang, W.4    Ganapathy, M.E.5    Leibach, F.H.6    Ganapathy, V.7
  • 88
    • 0036262643 scopus 로고    scopus 로고
    • ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline
    • Takanaga H, Tokuda N, Ohtsuki S, Hosoya K, Terasaki T (2002) ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline. Mol Pharmacol 61:1289-1296
    • (2002) Mol Pharmacol , vol.61 , pp. 1289-1296
    • Takanaga, H.1    Tokuda, N.2    Ohtsuki, S.3    Hosoya, K.4    Terasaki, T.5
  • 90
    • 0032964297 scopus 로고    scopus 로고
    • BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences
    • Tatusova TA, Madden TL (1999) BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences. FEMS Microbiol Lett 174:247-250
    • (1999) FEMS Microbiol Lett , vol.174 , pp. 247-250
    • Tatusova, T.A.1    Madden, T.L.2
  • 91
    • 0002834789 scopus 로고    scopus 로고
    • Biomembrane transport and interorgan nutrient flows: The amino acids
    • Van Winkle LJ (ed) Academic Press, San Diego
    • Taylor PM, Rennie MJ, Low SY (1999) Biomembrane transport and interorgan nutrient flows: the amino acids. In: Van Winkle LJ (ed) Biomembrane transport. Academic Press, San Diego, pp 295-325
    • (1999) Biomembrane Transport , pp. 295-325
    • Taylor, P.M.1    Rennie, M.J.2    Low, S.Y.3
  • 92
    • 0037195274 scopus 로고    scopus 로고
    • A PI3-kinase signaling code for insulin-triggered insertion of glucose transporters into the plasma membrane
    • Tengholm A, Meyer T (2002) A PI3-kinase signaling code for insulin-triggered insertion of glucose transporters into the plasma membrane. Curr Biol 12:1871-1876
    • (2002) Curr Biol , vol.12 , pp. 1871-1876
    • Tengholm, A.1    Meyer, T.2
  • 93
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673-4680
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 94
    • 0025204671 scopus 로고
    • Synthesis of transmitter glutamate and the glial-neuron interrelationship
    • Torgner I, Kvamme E (1990) Synthesis of transmitter glutamate and the glial-neuron interrelationship. Mol Chem Neuropathol 12:11-17
    • (1990) Mol Chem Neuropathol , vol.12 , pp. 11-17
    • Torgner, I.1    Kvamme, E.2
  • 95
    • 0037111409 scopus 로고    scopus 로고
    • The osmoprotective function of the NFAT5 transcription factor in T cell development and activation
    • Trama J, Go WY, Ho SN (2002) The osmoprotective function of the NFAT5 transcription factor in T cell development and activation. J Immunol 169:5477-5488
    • (2002) J Immunol , vol.169 , pp. 5477-5488
    • Trama, J.1    Go, W.Y.2    Ho, S.N.3
  • 96
    • 0036299010 scopus 로고    scopus 로고
    • Selective up-regulation of System A transporter mRNA in diabetic liver
    • Varoqui H, Erickson JD (2002) Selective up-regulation of System A transporter mRNA in diabetic liver. Biochem Biophys Res Commun 290:903-908
    • (2002) Biochem Biophys Res Commun , vol.290 , pp. 903-908
    • Varoqui, H.1    Erickson, J.D.2
  • 97
    • 0034635496 scopus 로고    scopus 로고
    • Cloning and functional identification of a neuronal glutamine transporter
    • Varoqui H, Zhu H, Yao D, Ming H, Erickson JD (2000) Cloning and functional identification of a neuronal glutamine transporter. J Biol Chem 275:4049-4054
    • (2000) J Biol Chem , vol.275 , pp. 4049-4054
    • Varoqui, H.1    Zhu, H.2    Yao, D.3    Ming, H.4    Erickson, J.D.5
  • 98
    • 0036140131 scopus 로고    scopus 로고
    • I transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses
    • I transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses. J Neurosci 22:142-155
    • (2002) J Neurosci , vol.22 , pp. 142-155
    • Varoqui, H.1    Schäfer, M.K.H.2    Zhu, H.3    Weihe, E.4    Erickson, J.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.