-
1
-
-
0033850407
-
Tau Protein Isoforms, Phosphorylation and Role in Neurodegenerative Disorders
-
Buee, L.; Bussiere, T.; Buee-Scherrer, V.; Delacourte, A.; Hof, P. R. Tau Protein Isoforms, Phosphorylation and Role in Neurodegenerative Disorders Brain Res. Rev. 2000, 33, 95-130
-
(2000)
Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buee, L.1
Bussiere, T.2
Buee-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
2
-
-
10944248857
-
Tau, Tangles, and Alzheimers Disease
-
Binder, L. I.; Guillozet-Bongaarts, A. L.; Garcia-Sierra, F.; Berry, R. W. Tau, Tangles, and Alzheimers Disease Biochim. Biophys. Acta 2005, 1739, 216-223
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 216-223
-
-
Binder, L.I.1
Guillozet-Bongaarts, A.L.2
Garcia-Sierra, F.3
Berry, R.W.4
-
3
-
-
65249116483
-
Tau Mutations in Neurodegenerative Diseases
-
Wolfe, M. S. Tau Mutations in Neurodegenerative Diseases J. Biol. Chem. 2009, 284, 6021-6025
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 6021-6025
-
-
Wolfe, M.S.1
-
4
-
-
0034718203
-
Tau Mutations in Frontotemporal Dementia Ftdp-17 and Their Relevance for Alzheimers Disease
-
Goedert, M.; Spillantini, M. G. Tau Mutations in Frontotemporal Dementia Ftdp-17 and Their Relevance for Alzheimers Disease Biochim. Biophys. Acta 2000, 1502, 110-121
-
(2000)
Biochim. Biophys. Acta
, vol.1502
, pp. 110-121
-
-
Goedert, M.1
Spillantini, M.G.2
-
5
-
-
0037135111
-
The Amyloid Hypothesis of Alzheimers Disease: Progress and Problems on the Road to Therapeutics
-
Hardy, J.; Selkoe, D. J. The Amyloid Hypothesis of Alzheimers Disease: Progress and Problems on the Road to Therapeutics Science 2002, 297, 353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
6
-
-
67849106670
-
Amyloid-β Protein Oligomerization and the Importance of Tetramers and Dodecamers in the Aetiology of Alzheimers Disease
-
Bernstein, S. L.; Dupuis, N. F.; Lazo, N. D.; Wyttenbach, T.; Condron, M. M.; Bitan, G.; Teplow, D. B.; Shea, J.-E.; Ruotolo, B. T.; Robinson, C. V.; Bowers, M. T. Amyloid-β Protein Oligomerization and the Importance of Tetramers and Dodecamers in the Aetiology of Alzheimers Disease Nat. Chem. 2009, 1, 326-331
-
(2009)
Nat. Chem.
, vol.1
, pp. 326-331
-
-
Bernstein, S.L.1
Dupuis, N.F.2
Lazo, N.D.3
Wyttenbach, T.4
Condron, M.M.5
Bitan, G.6
Teplow, D.B.7
Shea, J.-E.8
Ruotolo, B.T.9
Robinson, C.V.10
Bowers, M.T.11
-
7
-
-
84863229747
-
Atomic View of a Toxic Amyloid Small Oligomer
-
Laganowsky, A.; Liu, C.; Sawaya, M. R.; Whitelegge, J. P.; Park, J.; Zhao, M. L.; Pensalfini, A.; Soriaga, A. B.; Landau, M.; Teng, P. K.; Cascio, D.; Glabe, C.; Eisenberg, D. Atomic View of a Toxic Amyloid Small Oligomer Science 2012, 335, 1228-1231
-
(2012)
Science
, vol.335
, pp. 1228-1231
-
-
Laganowsky, A.1
Liu, C.2
Sawaya, M.R.3
Whitelegge, J.P.4
Park, J.5
Zhao, M.L.6
Pensalfini, A.7
Soriaga, A.B.8
Landau, M.9
Teng, P.K.10
Cascio, D.11
Glabe, C.12
Eisenberg, D.13
-
8
-
-
0035943436
-
Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ 42 Fibrils
-
Gotz, J.; Chen, F.; van Dorpe, J.; Nitsch, R. M. Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ 42 Fibrils Science 2001, 293, 1491-1495
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
9
-
-
34248560960
-
Amyloid-β in Alzheimer Disease: The Null Versus the Alternate Hypotheses
-
Lee, H. G.; Zhu, X. W.; Castellani, R. J.; Nunomura, A.; Perry, G.; Smith, M. A. Amyloid-β in Alzheimer Disease: The Null Versus the Alternate Hypotheses J. Pharmacol. Exp. Ther. 2007, 321, 823-829
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.321
, pp. 823-829
-
-
Lee, H.G.1
Zhu, X.W.2
Castellani, R.J.3
Nunomura, A.4
Perry, G.5
Smith, M.A.6
-
10
-
-
0038708285
-
Tangle and Neuron Numbers, but Not Amyloid Load, Predict Cognitive Status in Alzheimers Disease
-
Giannakopoulos, P.; Herrmann, F. R.; Bussiere, T.; Bouras, C.; Kovari, E.; Perl, D. P.; Morrison, J. H.; Gold, G.; Hof, P. R. Tangle and Neuron Numbers, but Not Amyloid Load, Predict Cognitive Status in Alzheimers Disease Neurology 2003, 60, 1495-1500
-
(2003)
Neurology
, vol.60
, pp. 1495-1500
-
-
Giannakopoulos, P.1
Herrmann, F.R.2
Bussiere, T.3
Bouras, C.4
Kovari, E.5
Perl, D.P.6
Morrison, J.H.7
Gold, G.8
Hof, P.R.9
-
11
-
-
80053589341
-
Membrane and Surface Interactions of Alzheimers Aβ Peptide - Insights into the Mechanism of Cytotoxicity
-
Williams, T. L.; Serpell, L. C. Membrane and Surface Interactions of Alzheimers Aβ Peptide - Insights into the Mechanism of Cytotoxicity FEBS J. 2011, 278, 3905-3917
-
(2011)
FEBS J.
, vol.278
, pp. 3905-3917
-
-
Williams, T.L.1
Serpell, L.C.2
-
12
-
-
0347753786
-
Two Types of Alzheimers β-Amyloid (1-40) Peptide Membrane Interactions: Aggregation Preventing Transmembrane Anchoring Versus Accelerated Surface Fibril Formation
-
Bokvist, M.; Lindstrom, F.; Watts, A.; Grobner, G. Two Types of Alzheimers β-Amyloid (1-40) Peptide Membrane Interactions: Aggregation Preventing Transmembrane Anchoring Versus Accelerated Surface Fibril Formation J. Mol. Biol. 2004, 335, 1039-1049
-
(2004)
J. Mol. Biol.
, vol.335
, pp. 1039-1049
-
-
Bokvist, M.1
Lindstrom, F.2
Watts, A.3
Grobner, G.4
-
13
-
-
34250819839
-
Intracellular Amyloid-β in Alzheimers Disease
-
LaFerla, F. M.; Green, K. N.; Oddo, S. Intracellular Amyloid-β in Alzheimers Disease Nat. Rev. Neurosci. 2007, 8, 499-509
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 499-509
-
-
Laferla, F.M.1
Green, K.N.2
Oddo, S.3
-
14
-
-
78650963274
-
Amyloid-Like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions
-
Olzscha, H.; Schermann, S. M.; Woerner, A. C.; Pinkert, S.; Hecht, M. H.; Tartaglia, G. G.; Vendruscolo, M.; Hayer-Hartl, M.; Hartl, F. U.; Vabulas, R. M. Amyloid-Like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions Cell 2011, 144, 67-78
-
(2011)
Cell
, vol.144
, pp. 67-78
-
-
Olzscha, H.1
Schermann, S.M.2
Woerner, A.C.3
Pinkert, S.4
Hecht, M.H.5
Tartaglia, G.G.6
Vendruscolo, M.7
Hayer-Hartl, M.8
Hartl, F.U.9
Vabulas, R.M.10
-
15
-
-
33751218015
-
Tau-Dependent Microtubule Disassembly Initiated by Prefibrillar β-Amyloid
-
King, M. E.; Kan, H. M.; Baas, P. W.; Erisir, A.; Glabe, C. G.; Bloom, G. S. Tau-Dependent Microtubule Disassembly Initiated by Prefibrillar β-Amyloid J. Cell Biol. 2006, 175, 541-546
-
(2006)
J. Cell Biol.
, vol.175
, pp. 541-546
-
-
King, M.E.1
Kan, H.M.2
Baas, P.W.3
Erisir, A.4
Glabe, C.G.5
Bloom, G.S.6
-
16
-
-
17944382037
-
Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP
-
Lewis, J.; Dickson, D. W.; Lin, W. L.; Chisholm, L.; Corral, A.; Jones, G.; Yen, S. H.; Sahara, N.; Skipper, L.; Yager, D.; Eckman, C.; Hardy, J.; Hutton, M.; McGowan, E. Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP Science 2001, 293, 1487-1491
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
17
-
-
79955044494
-
Soluble Amyloid β-Protein Dimers Isolated from Alzheimer Cortex Directly Induce Tau Hyperphosphorylation and Neuritic Degeneration
-
Jin, M.; Shepardson, N.; Yang, T.; Chen, G.; Walsh, D.; Selkoe, D. J. Soluble Amyloid β-Protein Dimers Isolated from Alzheimer Cortex Directly Induce Tau Hyperphosphorylation and Neuritic Degeneration Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 5819-5824
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 5819-5824
-
-
Jin, M.1
Shepardson, N.2
Yang, T.3
Chen, G.4
Walsh, D.5
Selkoe, D.J.6
-
18
-
-
84887828122
-
Amyloid-β Oligomers Induce Synaptic Damage Via Tau-Dependent Microtubule Severing by TTLL6 and Spastin
-
Zempel, H.; Luedtke, J.; Kumar, Y.; Biernat, J.; Dawson, H.; Mandelkow, E.; Mandelkow, E. M. Amyloid-β Oligomers Induce Synaptic Damage Via Tau-Dependent Microtubule Severing by TTLL6 and Spastin EMBO J. 2013, 32, 2920-2937
-
(2013)
EMBO J.
, vol.32
, pp. 2920-2937
-
-
Zempel, H.1
Luedtke, J.2
Kumar, Y.3
Biernat, J.4
Dawson, H.5
Mandelkow, E.6
Mandelkow, E.M.7
-
19
-
-
0037110601
-
Amyloid-β Peptide Induces Tau Phosphorylation and Loss of Cholinergic Neurons in Rat Primary Septal Cultures
-
Zheng, W. H.; Bastianetto, S.; Mennicken, F.; Ma, W.; Kar, S. Amyloid-β Peptide Induces Tau Phosphorylation and Loss of Cholinergic Neurons in Rat Primary Septal Cultures Neuroscience 2002, 115, 201-211
-
(2002)
Neuroscience
, vol.115
, pp. 201-211
-
-
Zheng, W.H.1
Bastianetto, S.2
Mennicken, F.3
Ma, W.4
Kar, S.5
-
20
-
-
67650729973
-
β-Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate Via C-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin
-
Ma, Q. L.; Yang, F.; Rosario, E. R.; Ubeda, O. J.; Beech, W.; Gant, D. J.; Chen, P. P.; Hudspeth, B.; Chen, C.; Zhao, Y.; Vinters, H. V.; Frautschy, S. A.; Cole, G. M. β-Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate Via C-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin J. Neurosci. 2009, 29, 9078-9089
-
(2009)
J. Neurosci.
, vol.29
, pp. 9078-9089
-
-
Ma, Q.L.1
Yang, F.2
Rosario, E.R.3
Ubeda, O.J.4
Beech, W.5
Gant, D.J.6
Chen, P.P.7
Hudspeth, B.8
Chen, C.9
Zhao, Y.10
Vinters, H.V.11
Frautschy, S.A.12
Cole, G.M.13
-
21
-
-
84867412992
-
Hyperphosphorylation of Tau Induced by Naturally Secreted Amyloid-B at Nanomolar Concentrations is Modulated by Insulin-Dependent AKT-GSK3β Signaling Pathway
-
Tokutake, T.; Kasuga, K.; Yajima, R.; Sekine, Y.; Tezuka, T.; Nishizawa, M.; Ikeuchi, T. Hyperphosphorylation of Tau Induced by Naturally Secreted Amyloid-B at Nanomolar Concentrations Is Modulated by Insulin-Dependent AKT-GSK3β Signaling Pathway J. Biol. Chem. 2012, 287, 35222-35233
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 35222-35233
-
-
Tokutake, T.1
Kasuga, K.2
Yajima, R.3
Sekine, Y.4
Tezuka, T.5
Nishizawa, M.6
Ikeuchi, T.7
-
22
-
-
78751644048
-
Amyloid-Beta and Tau - A Toxic Pas de Deux in Alzheimers Disease
-
Ittner, L. M.; Gotz, J. Amyloid-Beta and Tau - A Toxic Pas De Deux in Alzheimers Disease Nat. Rev. Neurosci. 2011, 12, 65-72
-
(2011)
Nat. Rev. Neurosci.
, vol.12
, pp. 65-72
-
-
Ittner, L.M.1
Gotz, J.2
-
23
-
-
32444432146
-
Aβ and Tau Form Soluble Complexes That May Promote Self Aggregation of Both into the Insoluble Forms Observed in Alzheimers Disease
-
Guo, J.-P.; Arai, T.; Miklossy, J.; McGeer, P. L. Aβ and Tau Form Soluble Complexes That May Promote Self Aggregation of Both into the Insoluble Forms Observed in Alzheimers Disease Proc. Natl. Acad. Sci. U. S. A. 2006, 103, 1953-1958
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 1953-1958
-
-
Guo, J.-P.1
Arai, T.2
Miklossy, J.3
McGeer, P.L.4
-
24
-
-
0037197836
-
Tau is Essential to β-Amyloid-Induced Neurotoxicity
-
Rapoport, M.; Dawson, H. N.; Binder, L. I.; Vitek, M. P.; Ferreira, A. Tau Is Essential to β-Amyloid-Induced Neurotoxicity Proc. Natl. Acad. Sci. U. S. A. 2002, 99, 6364-6369
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 6364-6369
-
-
Rapoport, M.1
Dawson, H.N.2
Binder, L.I.3
Vitek, M.P.4
Ferreira, A.5
-
25
-
-
0028986916
-
β-Amyloid Fibrils Induce Tau-Phosphorylation and Loss of Microtubule-Binding
-
Busciglio, J.; Lorenzo, A.; Yeh, J.; Yankner, B. A. β-Amyloid Fibrils Induce Tau-Phosphorylation and Loss of Microtubule-Binding Neuron 1995, 14, 879-888
-
(1995)
Neuron
, vol.14
, pp. 879-888
-
-
Busciglio, J.1
Lorenzo, A.2
Yeh, J.3
Yankner, B.A.4
-
26
-
-
0030879686
-
Selective Phosphorylation of Adult Tau Isoforms in Mature Hippocampal Neurons Exposed to Fibrillar Aβ
-
Ferreira, A.; Lu, Q.; Orecchio, L.; Kosik, K. S. Selective Phosphorylation of Adult Tau Isoforms in Mature Hippocampal Neurons Exposed to Fibrillar Aβ Mol. Cell. Neurosci. 1997, 9, 220-234
-
(1997)
Mol. Cell. Neurosci.
, vol.9
, pp. 220-234
-
-
Ferreira, A.1
Lu, Q.2
Orecchio, L.3
Kosik, K.S.4
-
27
-
-
0031695652
-
Activation of Tau Protein Kinase I/Glycogen Synthase Kinase-3beta by Amyloid-β Peptide (25-35) Enhances Phosphorylation of Tau in Hippocampal Neurons
-
Takashima, A.; Honda, T.; Yasutake, K.; Michel, G.; Murayama, O.; Murayama, M.; Ishiguro, K.; Yamaguchi, H. Activation of Tau Protein Kinase I/Glycogen Synthase Kinase-3beta by Amyloid-β Peptide (25-35) Enhances Phosphorylation of Tau in Hippocampal Neurons Neurosci. Res. 1998, 31, 317-323
-
(1998)
Neurosci. Res.
, vol.31
, pp. 317-323
-
-
Takashima, A.1
Honda, T.2
Yasutake, K.3
Michel, G.4
Murayama, O.5
Murayama, M.6
Ishiguro, K.7
Yamaguchi, H.8
-
28
-
-
77950276918
-
Structural Diversity of Dimers of the Alzheimer Amyloid-β(25-35) Peptide and Polymorphism of the Resulting Fibrils
-
Wei, G.; Jewett, A. I.; Shea, J. E. Structural Diversity of Dimers of the Alzheimer Amyloid-β(25-35) Peptide and Polymorphism of the Resulting Fibrils Phys. Chem. Chem. Phys. 2010, 12, 3622-3629
-
(2010)
Phys. Chem. Chem. Phys.
, vol.12
, pp. 3622-3629
-
-
Wei, G.1
Jewett, A.I.2
Shea, J.E.3
-
29
-
-
33748473035
-
Effects of Solvent on the Structure of the Alzheimer Amyloid-β (25-35) Peptide
-
Wei, G. H.; Shea, J. E. Effects of Solvent on the Structure of the Alzheimer Amyloid-β (25-35) Peptide Biophys. J. 2006, 91, 1638-1647
-
(2006)
Biophys. J.
, vol.91
, pp. 1638-1647
-
-
Wei, G.H.1
Shea, J.E.2
-
30
-
-
84878078985
-
Initiation of Assembly of Tau(273-284) and Its K280 Mutant: An Experimental and Computational Study
-
Larini, L.; Gessel, M. M.; Lapointe, N. E.; Do, T. D.; Bowers, M. T.; Feinstein, S. C.; Shea, J. E. Initiation of Assembly of Tau(273-284) and Its K280 Mutant: An Experimental and Computational Study Phys. Chem. Chem. Phys. 2013, 15, 8916-8928
-
(2013)
Phys. Chem. Chem. Phys.
, vol.15
, pp. 8916-8928
-
-
Larini, L.1
Gessel, M.M.2
Lapointe, N.E.3
Do, T.D.4
Bowers, M.T.5
Feinstein, S.C.6
Shea, J.E.7
-
31
-
-
84864686048
-
Role of B-Hairpin Formation in Aggregation: The Self-Assembly of the Amyloid-β (25-35) Peptide
-
Larini, L.; Shea, J. E. Role of B-Hairpin Formation in Aggregation: The Self-Assembly of the Amyloid-β (25-35) Peptide Biophys. J. 2012, 103, 576-586
-
(2012)
Biophys. J.
, vol.103
, pp. 576-586
-
-
Larini, L.1
Shea, J.E.2
-
32
-
-
84887736083
-
Ion Mobility Spectrometry Reveals the Mechanism of Amyloid Formation of Aβ(25-35) and Its Modulation by Inhibitors at the Molecular Level: Epigallocatechin Gallate and Scyllo-Inositol
-
Bleiholder, C.; Do, T. D.; Wu, C.; Economou, N. J.; Bernstein, S. S.; Buratto, S. K.; Shea, J.-E.; Bowers, M. T. Ion Mobility Spectrometry Reveals the Mechanism of Amyloid Formation of Aβ(25-35) and Its Modulation by Inhibitors at the Molecular Level: Epigallocatechin Gallate and Scyllo-Inositol J. Am. Chem. Soc. 2013, 135, 16926-16937
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 16926-16937
-
-
Bleiholder, C.1
Do, T.D.2
Wu, C.3
Economou, N.J.4
Bernstein, S.S.5
Buratto, S.K.6
Shea, J.-E.7
Bowers, M.T.8
-
33
-
-
78649570071
-
Disordered Versus Fibril-Like Amyloid-β (25-35) Dimers in Water: Structure and Thermodynamics
-
Kittner, M.; Knecht, V. Disordered Versus Fibril-Like Amyloid-β (25-35) Dimers in Water: Structure and Thermodynamics J. Phys. Chem. B 2010, 114, 15288-15295
-
(2010)
J. Phys. Chem. B
, vol.114
, pp. 15288-15295
-
-
Kittner, M.1
Knecht, V.2
-
34
-
-
19444383084
-
Aβ(31-35) and Aβ(25-35) Fragments of Amyloid Beta-Protein Induce Cellular Death through Apoptotic Signals: Role of the Redox State of Methionine-35
-
Clementi, M. E.; Marini, S.; Coletta, M.; Orsini, F.; Giardina, B.; Misiti, F. Aβ(31-35) and Aβ(25-35) Fragments of Amyloid Beta-Protein Induce Cellular Death through Apoptotic Signals: Role of the Redox State of Methionine-35 FEBS Lett. 2005, 579, 2913-2918
-
(2005)
FEBS Lett.
, vol.579
, pp. 2913-2918
-
-
Clementi, M.E.1
Marini, S.2
Coletta, M.3
Orsini, F.4
Giardina, B.5
Misiti, F.6
-
35
-
-
0028981219
-
Structure-Activity Analyses of β-Amyloid Peptides - Contributions of the Beta-25-35 Region to Aggregation and Neurotoxicity
-
Pike, C. J.; Walencewiczwasserman, A. J.; Kosmoski, J.; Cribbs, D. H.; Glabe, C. G.; Cotman, C. W. Structure-Activity Analyses of β-Amyloid Peptides-Contributions of the Beta-25-35 Region to Aggregation and Neurotoxicity J. Neurochem. 1995, 64, 253-265
-
(1995)
J. Neurochem.
, vol.64
, pp. 253-265
-
-
Pike, C.J.1
Walencewiczwasserman, A.J.2
Kosmoski, J.3
Cribbs, D.H.4
Glabe, C.G.5
Cotman, C.W.6
-
36
-
-
83455171054
-
Secondary Nucleating Sequences Affect Kinetics and Thermodynamics of Tau Aggregation
-
Moore, C. L.; Huang, M. H.; Robbennolt, S. A.; Voss, K. R.; Combs, B.; Gamblin, T. C.; Goux, W. J. Secondary Nucleating Sequences Affect Kinetics and Thermodynamics of Tau Aggregation Biochemistry 2011, 50, 10876-10886
-
(2011)
Biochemistry
, vol.50
, pp. 10876-10886
-
-
Moore, C.L.1
Huang, M.H.2
Robbennolt, S.A.3
Voss, K.R.4
Combs, B.5
Gamblin, T.C.6
Goux, W.J.7
-
37
-
-
33845926113
-
Characterization of Two VQIXXK Motifs for Tau Fibrillization in Vitro
-
Li, W. K.; Lee, V. M. Y. Characterization of Two VQIXXK Motifs for Tau Fibrillization in Vitro Biochemistry 2006, 45, 15692-15701
-
(2006)
Biochemistry
, vol.45
, pp. 15692-15701
-
-
Li, W.K.1
Lee, V.M.Y.2
-
38
-
-
3042602456
-
The Formation of Straight and Twisted Filaments from Short Tau Peptides
-
Goux, W. J.; Kopplin, L.; Nguyen, A. D.; Leak, K.; Rutkofsky, M.; Shanmuganandam, V. D.; Sharma, D.; Inouye, H.; Kirschner, D. A. The Formation of Straight and Twisted Filaments from Short Tau Peptides J. Biol. Chem. 2004, 279, 26868-26875
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26868-26875
-
-
Goux, W.J.1
Kopplin, L.2
Nguyen, A.D.3
Leak, K.4
Rutkofsky, M.5
Shanmuganandam, V.D.6
Sharma, D.7
Inouye, H.8
Kirschner, D.A.9
-
39
-
-
0035930625
-
Mutations of Tau Protein in Frontotemporal Dementia Promote Aggregation of Paired Helical Filaments by Enhancing Local β-Structure
-
von Bergen, M.; Barghorn, S.; Li, L.; Marx, A.; Biernat, J.; Mandelkow, E. M.; Mandelkow, E. Mutations of Tau Protein in Frontotemporal Dementia Promote Aggregation of Paired Helical Filaments by Enhancing Local β-Structure J. Biol. Chem. 2001, 276, 48165-48174
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48165-48174
-
-
Von Bergen, M.1
Barghorn, S.2
Li, L.3
Marx, A.4
Biernat, J.5
Mandelkow, E.M.6
Mandelkow, E.7
-
40
-
-
79958821061
-
Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation Via Polymorphic States
-
Miller, Y.; Ma, B.; Nussinov, R. Synergistic Interactions between Repeats in Tau Protein and Aβ Amyloids May Be Responsible for Accelerated Aggregation Via Polymorphic States Biochemistry 2011, 50, 5172-5181
-
(2011)
Biochemistry
, vol.50
, pp. 5172-5181
-
-
Miller, Y.1
Ma, B.2
Nussinov, R.3
-
41
-
-
17144409371
-
Three- and Four-Repeat Tau Regulate the Dynamic Instability of Two Distinct Microtubule Subpopulations in Qualitatively Different Manners. Implications for Neurodegeneration
-
Levy, S. F.; Leboeuf, A. C.; Massie, M. R.; Jordan, M. A.; Wilson, L.; Feinstein, S. C. Three- and Four-Repeat Tau Regulate the Dynamic Instability of Two Distinct Microtubule Subpopulations in Qualitatively Different Manners. Implications for Neurodegeneration J. Biol. Chem. 2005, 280, 13520-13528
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 13520-13528
-
-
Levy, S.F.1
Leboeuf, A.C.2
Massie, M.R.3
Jordan, M.A.4
Wilson, L.5
Feinstein, S.C.6
-
42
-
-
80054752317
-
Molecular Basis for Amyloid-β Polymorphism
-
Colletiera, J.-P.; Laganowskya, A.; Landau, M.; Zhao, M.; Soriaga, A. B.; Goldschmidt, L.; Flot, D.; Cascio, D.; Sawaya, M. R.; Eisenberg, D. Molecular Basis for Amyloid-β Polymorphism Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 16938-16943
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 16938-16943
-
-
Colletiera, J.-P.1
Laganowskya, A.2
Landau, M.3
Zhao, M.4
Soriaga, A.B.5
Goldschmidt, L.6
Flot, D.7
Cascio, D.8
Sawaya, M.R.9
Eisenberg, D.10
-
43
-
-
34249290108
-
Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers
-
Sawaya, M. R.; Sambashivan, S.; Nelson, R.; Ivanova, M. I.; Sievers, S. A.; Apostol, M. I.; Thompson, M. J.; Balbirnie, M.; Wiltzius, J. J. W.; MacFarlane, H. T.; Madsen, A. Ø.; Riekel, C.; Eisenberg, D. Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers Nature 2007, 447, 453-457
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
Sambashivan, S.2
Nelson, R.3
Ivanova, M.I.4
Sievers, S.A.5
Apostol, M.I.6
Thompson, M.J.7
Balbirnie, M.8
Wiltzius, J.J.W.9
Macfarlane, H.T.10
Madsen A.Ø11
Riekel, C.12
Eisenberg, D.13
-
44
-
-
70349730066
-
A New, Higher Resolution, Ion Mobility Mass Spectrometer
-
Kemper, P. R.; Dupuis, N. F.; Bowers, M. T. A New, Higher Resolution, Ion Mobility Mass Spectrometer Int. J. Mass. Spectrom. 2009, 287, 46-57
-
(2009)
Int. J. Mass. Spectrom.
, vol.287
, pp. 46-57
-
-
Kemper, P.R.1
Dupuis, N.F.2
Bowers, M.T.3
-
46
-
-
84880555312
-
Factors That Drive Peptide Assembly and Fibril Formation: Experimental and Theoretical Analysis of Sup35 NNQQNY Mutants
-
Do, T. D.; Economou, N. J.; LaPointe, N. E.; Kincannon, W. M.; Bleiholder, C.; Feinstein, S. C.; Teplow, D. B.; Buratto, S. K.; Bowers, M. T. Factors That Drive Peptide Assembly and Fibril Formation: Experimental and Theoretical Analysis of Sup35 NNQQNY Mutants J. Phys. Chem. B 2013, 117, 8436-8446
-
(2013)
J. Phys. Chem. B
, vol.117
, pp. 8436-8446
-
-
Do, T.D.1
Economou, N.J.2
Lapointe, N.E.3
Kincannon, W.M.4
Bleiholder, C.5
Feinstein, S.C.6
Teplow, D.B.7
Buratto, S.K.8
Bowers, M.T.9
-
47
-
-
46249092554
-
Gromacs 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
-
Hess, B.; Kutzner, C.; van der Spoel, D.; Lindahl, E. Gromacs 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation J. Chem. Theory Comput. 2008, 4, 435-437
-
(2008)
J. Chem. Theory Comput.
, vol.4
, pp. 435-437
-
-
Hess, B.1
Kutzner, C.2
Van Der Spoel, D.3
Lindahl, E.4
-
48
-
-
27344454932
-
Gromacs: Fast, Flexible, and Free
-
Spoel, D. V. D.; Lindahl, E.; Hess, B.; Groenhof, G.; Mark, A. E.; Berendsen, H. J. C. Gromacs: Fast, Flexible, and Free J. Comput. Chem. 2005, 26, 1701-1718
-
(2005)
J. Comput. Chem.
, vol.26
, pp. 1701-1718
-
-
Spoel, D.V.D.1
Lindahl, E.2
Hess, B.3
Groenhof, G.4
Mark, A.E.5
Berendsen, H.J.C.6
-
49
-
-
56349105206
-
OPLS-2002: A New Version of the OPLS-AA Force Field
-
Damm, W.; Halgren, T. A.; Murphy, R. B.; Smondyrev, A. M.; Friesner, R. A.; Jorgensen, W. L. OPLS-2002: A New Version of the OPLS-AA Force Field Abstr. Pap. Am. Chem. Soc. 2002, 224, U471-U471
-
(2002)
Abstr. Pap. Am. Chem. Soc.
, vol.224
, pp. 471-U471
-
-
Damm, W.1
Halgren, T.A.2
Murphy, R.B.3
Smondyrev, A.M.4
Friesner, R.A.5
Jorgensen, W.L.6
-
50
-
-
84894670314
-
Extending the OPLS-AA Force Field for Ligand Functionality
-
Halgren, T. A.; Murphy, R. B.; Jorgensen, W. L.; Friesner, R. A. Extending the OPLS-AA Force Field for Ligand Functionality Abstr. Pap. Am. Chem. Soc. 2000, 220, U277-U277
-
(2000)
Abstr. Pap. Am. Chem. Soc.
, vol.220
, pp. 277-U277
-
-
Halgren, T.A.1
Murphy, R.B.2
Jorgensen, W.L.3
Friesner, R.A.4
-
51
-
-
33645941402
-
The Opls Potential Functions for Proteins. Energy Minimizations for Crystals of Cyclic Peptides and Crambin
-
Jorgensen, W. L.; Tirado-Rives, J. The Opls Potential Functions for Proteins. Energy Minimizations for Crystals of Cyclic Peptides and Crambin J. Am. Chem. Soc. 1988, 110, 1657-1666
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 1657-1666
-
-
Jorgensen, W.L.1
Tirado-Rives, J.2
-
52
-
-
33746817286
-
OPLS-AA/L Force Field for Proteins: Using Accurate Quantum Mechanical Data
-
Kaminski, G. A.; Friesner, R. A.; Tirado-Rives, J.; Jorgensen, W. L. OPLS-AA/L Force Field for Proteins: Using Accurate Quantum Mechanical Data Abstr. Pap. Am. Chem. Soc. 2000, 220, U279-U279
-
(2000)
Abstr. Pap. Am. Chem. Soc.
, vol.220
, pp. 279-U279
-
-
Kaminski, G.A.1
Friesner, R.A.2
Tirado-Rives, J.3
Jorgensen, W.L.4
-
53
-
-
0004016501
-
Comparison of Simple Potential Functions for Simulating Liquid Water
-
Jorgensen, W. L.; Chandrasekhar, J.; Madura, J. D.; Impey, R. W.; Klein, M. L. Comparison of Simple Potential Functions for Simulating Liquid Water J. Chem. Phys. 1983, 79, 926-935
-
(1983)
J. Chem. Phys.
, vol.79
, pp. 926-935
-
-
Jorgensen, W.L.1
Chandrasekhar, J.2
Madura, J.D.3
Impey, R.W.4
Klein, M.L.5
-
54
-
-
33748887803
-
Structural Information from Ion Mobility Measurements: Effects of the Long Range Potential
-
Mesleh, M. F.; Hunter, J. M.; Shvartsburg, A. A.; Schatz, G. C.; Jarrold, M. F. Structural Information from Ion Mobility Measurements: Effects of the Long Range Potential J. Phys. Chem. A 1996, 100, 16082-16086
-
(1996)
J. Phys. Chem. A
, vol.100
, pp. 16082-16086
-
-
Mesleh, M.F.1
Hunter, J.M.2
Shvartsburg, A.A.3
Schatz, G.C.4
Jarrold, M.F.5
-
55
-
-
0030580028
-
An Exact Hard-Spheres Scattering Model for the Mobilities of Polyatomic Ions
-
Shvartsburg, A. A.; Jarrold, M. F. An Exact Hard-Spheres Scattering Model for the Mobilities of Polyatomic Ions Chem. Phys. Lett. 1996, 261, 86-91
-
(1996)
Chem. Phys. Lett.
, vol.261
, pp. 86-91
-
-
Shvartsburg, A.A.1
Jarrold, M.F.2
-
56
-
-
79251631002
-
Ion Mobility-Mass Spectrometry Reveals a Conformational Conversion from Random Assembly to β-Sheet in Amyloid Fibril Formation
-
Bleiholder, C.; Dupuis, N. F.; Wyttenbach, T.; Bowers, M. T. Ion Mobility-Mass Spectrometry Reveals a Conformational Conversion from Random Assembly to β-Sheet in Amyloid Fibril Formation Nat. Chem. 2011, 3, 172-177
-
(2011)
Nat. Chem.
, vol.3
, pp. 172-177
-
-
Bleiholder, C.1
Dupuis, N.F.2
Wyttenbach, T.3
Bowers, M.T.4
-
57
-
-
0001616080
-
Replica-Exchange Molecular Dynamics Method for Protein Folding
-
Sugita, Y.; Okamoto, Y. Replica-Exchange Molecular Dynamics Method for Protein Folding Chem. Phys. Lett. 1999, 314, 141-151
-
(1999)
Chem. Phys. Lett.
, vol.314
, pp. 141-151
-
-
Sugita, Y.1
Okamoto, Y.2
-
58
-
-
84870514804
-
Projection Approximation Algorithm for the Fast and Accurate Computation of Molecular Collision Cross Sections (III): Application to Supramolecular Coordination-Driven Assemblies with Complex Shapes
-
Anderson, S. E.; Bleiholder, C.; Brocker, E. R.; Stang, P. J.; Bowers, M. T.; Novel, A. Projection Approximation Algorithm for the Fast and Accurate Computation of Molecular Collision Cross Sections (III): Application to Supramolecular Coordination-Driven Assemblies with Complex Shapes Int. J. Mass. Spectrom. 2012, 330, 78-84
-
(2012)
Int. J. Mass. Spectrom.
, vol.330
, pp. 78-84
-
-
Anderson, S.E.1
Bleiholder, C.2
Brocker, E.R.3
Stang, P.J.4
Bowers, M.T.5
Novel, A.6
-
59
-
-
84888289286
-
Projection Approximation Algorithm for the Fast and Accurate Computation of Molecular Collision Cross Sections (IV). Application to Polypeptides
-
Bleiholder, C.; Contreras, S.; Bowers, M. T.; Novel, A. Projection Approximation Algorithm for the Fast and Accurate Computation of Molecular Collision Cross Sections (IV). Application to Polypeptides Int. J. Mass. Spectrom. 2013, 354, 275-280
-
(2013)
Int. J. Mass. Spectrom.
, vol.354
, pp. 275-280
-
-
Bleiholder, C.1
Contreras, S.2
Bowers, M.T.3
Novel, A.4
-
60
-
-
69949187643
-
Molecular Mechanisms for Protein-Encoded Inheritance
-
Wiltzius, J. J. W.; Landau, M.; Nelson, R.; Sawaya, M. R.; Apostol, M. I.; Goldschmidt, L.; Soriaga, A. B.; Cascio, D.; Rajashankar, K.; Eisenberg, D. Molecular Mechanisms for Protein-Encoded Inheritance Nat. Struct. Mol. Biol. 2009, 16, U973-U998
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 973-U998
-
-
Wiltzius, J.J.W.1
Landau, M.2
Nelson, R.3
Sawaya, M.R.4
Apostol, M.I.5
Goldschmidt, L.6
Soriaga, A.B.7
Cascio, D.8
Rajashankar, K.9
Eisenberg, D.10
-
61
-
-
84903766727
-
Factors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin Mutants
-
Do, T. D.; LaPointe, N. E.; Sangwan, S.; Teplow, D. B.; Feinstein, S. C.; Sawaya, M. R.; Eisenberg, D. S.; Bowers, M. T. Factors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin Mutants J. Phys. Chem. B 2014, 118, 7247-7256
-
(2014)
J. Phys. Chem. B
, vol.118
, pp. 7247-7256
-
-
Do, T.D.1
Lapointe, N.E.2
Sangwan, S.3
Teplow, D.B.4
Feinstein, S.C.5
Sawaya, M.R.6
Eisenberg, D.S.7
Bowers, M.T.8
-
62
-
-
33947691643
-
Granular Tau Oligomers as Intermediates of Tau Filaments
-
Maeda, S.; Sahara, N.; Saito, Y.; Murayama, M.; Yoshiike, Y.; Kim, H.; Miyasaka, T.; Murayama, S.; Ikai, A.; Takashima, A. Granular Tau Oligomers as Intermediates of Tau Filaments Biochemistry 2007, 46, 3856-3861
-
(2007)
Biochemistry
, vol.46
, pp. 3856-3861
-
-
Maeda, S.1
Sahara, N.2
Saito, Y.3
Murayama, M.4
Yoshiike, Y.5
Kim, H.6
Miyasaka, T.7
Murayama, S.8
Ikai, A.9
Takashima, A.10
|