-
1
-
-
84898057274
-
Altered ceramide acyl chain length and ceramide synthase gene expression in parkinson's disease
-
Abbott SK, Li H, Muñoz SS, Knoch B., Batterham M, Murphy KE, Halliday G.M., Garner B. Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson's disease. Mov Disord 2014; 29: 518-526.
-
(2014)
Mov Disord
, vol.29
, pp. 518-526
-
-
Abbott, S.K.1
Li, H.2
Muñoz, S.S.3
Knoch, B.4
Batterham, M.5
Murphy, K.E.6
Halliday, G.M.7
Garner, B.8
-
2
-
-
38549094208
-
Alpha-synuclein de creases arachidonic acid incorporation into rat striatal sy na-pto neurosomes
-
Adamczyk A, Kacprzak M, Kazmierczak A. Alpha-synuclein de creases arachidonic acid incorporation into rat striatal sy na-pto neurosomes. Folia Neuropathol 2007; 45: 230-235.
-
(2007)
Folia Neuropathol
, vol.45
, pp. 230-235
-
-
Adamczyk, A.1
Kacprzak, M.2
Kazmierczak, A.3
-
3
-
-
12444323123
-
Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: Role of bcl-2 expression
-
Bektas M, Jolly PS, Müller C, Eberle J., Spiegel S, Geilen CC. Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression. Oncogene 2005; 24: 178-187.
-
(2005)
Oncogene
, vol.24
, pp. 178-187
-
-
Bektas, M.1
Jolly, P.S.2
Müller, C.3
Eberle, J.4
Spiegel, S.5
Geilen, C.C.6
-
4
-
-
30544434809
-
Regulation by sphingosine 1-phosphate of bax and bad activities during apoptosis in a MEK-dependent manner
-
Betito S, Cuvillier O. Regulation by sphingosine 1-phosphate of Bax and Bad activities during apoptosis in a MEK-dependent manner. Biochem Biophys Res Commun 2006; 340: 1273-1277.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 1273-1277
-
-
Betito, S.1
Cuvillier, O.2
-
5
-
-
0030066567
-
Ceramide induces apoptosis in cultured mesencephalic neurons
-
Brugg B, Michel PP, Agid Y, Ruberg M. Ceramide induces apoptosis in cultured mesencephalic neurons. Neurochem J 1996; 66: 733-739.
-
(1996)
Neurochem J
, vol.66
, pp. 733-739
-
-
Brugg, B.1
Michel, P.P.2
Agid, Y.3
Ruberg, M.4
-
6
-
-
84902831529
-
Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in alzheimer's disease
-
Ceccom J, Loukh N, Lauwers-Cances V, Touriol C., Nicaise Y, Gentil C, Uro-Coste E, Pitson S., Maurage CA, Duyckaerts C, Cuvillier O, Delisle MB Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease. Acta Neuropathol Commun 2014; 2: 12.
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 12
-
-
Ceccom, J.1
Loukh, N.2
Lauwers-Cances, V.3
Touriol, C.4
Nicaise, Y.5
Gentil, C.6
Uro-Coste, E.7
Pitson, S.8
Maurage, C.A.9
Duyckaerts, C.10
Cuvillier, O.11
Delisle, M.B.12
-
7
-
-
79952237910
-
Lipid pathway alterations in parkinson's disease primary visual cortex
-
Cheng D, Jenner AM, Shui G, Cheong W.F., Mitchell TW, Nealon JR, Kim WS, McCann H, Wenk M.R., Halliday GM, Garner B. Lipid pathway alterations in Parkinson's disease primary visual cortex. PLoS One 2011; 6: e17299.
-
(2011)
PLoS One
, vol.6
, pp. e17299
-
-
Cheng, D.1
Jenner, A.M.2
Shui, G.3
Cheong, W.F.4
Mitchell, T.W.5
Nealon, J.R.6
Kim, W.S.7
McCann, H.8
Wenk, M.R.9
Halliday, G.M.10
Garner, B.11
-
8
-
-
84875740004
-
Docosahexaenoic acid and tetracyclines as promising neuroprotective compounds with poly(ADP-ribose) polymerase inhibitory activities for oxidative/ genotoxic stress treatment
-
Cieslik M, Pyszko J, Strosznajder JB Docosahexaenoic acid and tetracyclines as promising neuroprotective compounds with poly(ADP-ribose) polymerase inhibitory activities for oxidative/ genotoxic stress treatment. Neurochem Int 2013; 62: 626-636.
-
(2013)
Neurochem Int
, vol.62
, pp. 626-636
-
-
Cieslik, M.1
Pyszko, J.2
Strosznajder, J.B.3
-
9
-
-
73649096618
-
Disruption of sphingosine 1-phosphate lyase confers resistance to chemotherapy and promotes oncogenesis through bcl-2/Bcl-xL up-regulation
-
Colié S, Van Veldhoven PP, Kedjouar B, Bedia C, Albinet V, Sorli SC, Garcia V Djavaheri-Mergny M, Bauvy C, Codogno P, Levade T, Andrieu-Abadie N. Disruption of sphingosine 1-phosphate lyase confers resistance to chemotherapy and promotes oncogenesis through Bcl-2/Bcl-xL up-regulation. Cancer Res 2009; 69: 9346-9353.
-
(2009)
Cancer Res
, vol.69
, pp. 9346-9353
-
-
Colié, S.1
Van Veldhoven, P.P.2
Kedjouar, B.3
Bedia, C.4
Albinet, V.5
Sorli, S.C.6
Garcia, V.7
Djavaheri-Mergny, M.8
Bauvy, C.9
Codogno, P.10
Levade, T.11
Andrieu-Abadie, N.12
-
10
-
-
84902810539
-
Loss of the neuroprotective factor sphingosine 1-phosphate early in alzheimer's disease patho-genesis
-
Couttas TA, Kain N, Daniels B., Lim XY, Shepherd C, Kril J, Pickford R., Li H, Garner B, Don AS Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer's disease patho-genesis. Acta Neuropathol Commun 2014; 2: 9.
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 9
-
-
Couttas, T.A.1
Kain, N.2
Daniels, B.3
Lim, X.Y.4
Shepherd, C.5
Kril, J.6
Pickford, R.7
Li, H.8
Garner, B.9
Don, A.S.10
-
11
-
-
84911006921
-
Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phos-phate
-
Czubowicz K, Strosznajder R. Ceramide in the Molecular Mechanisms of Neuronal Cell Death. The Role of Sphingosine-1-Phos-phate. Mol Neurobiol 2014; doi: 10.1007/s12035-013-8606-4.
-
(2014)
Mol Neurobiol
-
-
Czubowicz, K.1
Strosznajder, R.2
-
12
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta SR, Dudek H, Tao X., Masters S, Fu H, Gotoh Y., Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91: 231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
13
-
-
0030780015
-
Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
-
Edsall LC, Pirianov GG, Spiegel S. Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. J Neurosci 1997; 17: 6952-6960.
-
(1997)
J Neurosci
, vol.17
, pp. 6952-6960
-
-
Edsall, L.C.1
Pirianov, G.G.2
Spiegel, S.3
-
14
-
-
84855973361
-
Severe alterations in lipid composition of frontal cortex lipid rafts from parkinson's disease and incidental parkinson's disease
-
Fabelo N, Martín V, Santpere G., Marín R, Torrent L., Ferrer I, Díaz M. Severe alterations in lipid composition of frontal cortex lipid rafts from Parkinson's disease and incidental Parkinson's disease. Mol Med 2011; 17: 1107-1118.
-
(2011)
Mol Med
, vol.17
, pp. 1107-1118
-
-
Fabelo, N.1
Martín, V.2
Santpere, G.3
Marín, R.4
Torrent, L.5
Ferrer, I.6
Díaz, M.7
-
15
-
-
3342951965
-
Lipid rafts mediate the synaptic localization of alpha-synuclein
-
Fortin DL, Troyer MD, Nakamura K, Kubo S., Anthony MD, Edwards RH. Lipid rafts mediate the synaptic localization of alpha-synuclein. J Neurosci 2004; 24: 6715-6723.
-
(2004)
J Neurosci
, vol.24
, pp. 6715-6723
-
-
Fortin, D.L.1
Troyer, M.D.2
Nakamura, K.3
Kubo, S.4
Anthony, M.D.5
Edwards, R.H.6
-
16
-
-
77953790503
-
An update on sphingosine-1-phosphate and other sphingolipid mediators
-
Fyrst H, Saba JD An update on sphingosine-1-phosphate and other sphingolipid mediators. Nat Chem Biol 2010; 6: 489-497.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 489-497
-
-
Fyrst, H.1
Saba, J.D.2
-
17
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
Giasson B, Duda JE, Murray I V, Chen Q, Souza J.M., Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 2000; 290: 985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
18
-
-
0037052633
-
MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells
-
Gómez-Santos C., Ferrer I, Reiriz J., Viñals F, Barrachina M., Ambrosio S. MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells. Brain Res 2002; 935: 32-39.
-
(2002)
Brain Res
, vol.935
, pp. 32-39
-
-
Gómez-Santos, C.1
Ferrer, I.2
Reiriz, J.3
Viñals, F.4
Barrachina, M.5
Ambrosio, S.6
-
19
-
-
69949113620
-
Regulation of histone acetylation in the nucleus by sphin-gosine-1-phosphate
-
Hait NC, Allegood J, Maceyka M., Strub GM, Harikumar KB, Singh SK, Luo C, Marmorstein R., Kordula T, Milstien S, Spiegel S. Regulation of histone acetylation in the nucleus by sphin-gosine-1-phosphate. Science 2009; 325: 1254-1257.
-
(2009)
Science
, vol.325
, pp. 1254-1257
-
-
Hait, N.C.1
Allegood, J.2
Maceyka, M.3
Strub, G.M.4
Harikumar, K.B.5
Singh, S.K.6
Luo, C.7
Marmorstein, R.8
Kordula, T.9
Milstien, S.10
Spiegel, S.11
-
20
-
-
79551519276
-
α-synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
-
Hansen C, Angot E, Bergström AL, Steiner J.A., Pieri L., Paul G, Outeiro T F, Melki R, Kallunki P, Fog K, Li JY, Brundin P. α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J Clin Invest 2011; 121: 715-725.
-
(2011)
J Clin Invest
, vol.121
, pp. 715-725
-
-
Hansen, C.1
Angot, E.2
Bergström, A.L.3
Steiner, J.A.4
Pieri, L.5
Paul, G.6
Outeiro, T.F.7
Melki, R.8
Kallunki, P.9
Fog, K.10
Li, J.Y.11
Brundin, P.12
-
21
-
-
74149083982
-
Deregulation of sphingolipid metabolism in alzheimer's disease
-
He X, Huang Y, Li B., Gong CX, Schuchman EH. Deregulation of sphingolipid metabolism in Alzheimer's disease. Neurobiol Aging 2010; 31: 398-408.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 398-408
-
-
He, X.1
Huang, Y.2
Li, B.3
Gong, C.X.4
Schuchman, E.H.5
-
22
-
-
0142091073
-
Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis
-
Igarashi N, Okada T, Hayashi S., Fujita T, Jahangeer S, Nakamura S. Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis. J Biol Chem 2003; 278: 46832-46839.
-
(2003)
J Biol Chem
, vol.278
, pp. 46832-46839
-
-
Igarashi, N.1
Okada, T.2
Hayashi, S.3
Fujita, T.4
Jahangeer, S.5
Nakamura, S.6
-
23
-
-
33947577504
-
Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and alzheimer's disease: A shift toward ceramide accumulation at the earliest recognizable stages of alzheimer's disease?
-
Katsel P, Li C, Haroutunian V. Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease? Neurochem Res 2007; 32: 845-856.
-
(2007)
Neurochem Res
, vol.32
, pp. 845-856
-
-
Katsel, P.1
Li, C.2
Haroutunian, V.3
-
24
-
-
84878411147
-
Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by tran-scriptional profling
-
Korecka JA, van Kesteren RE, Blaas E, Spitzer SO, Kamstra J.H., Smit AB, Swaab D F, Verhaagen J, Bossers K. Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by tran-scriptional profling. PLoS One 2013; 8: e63862.
-
(2013)
PLoS One
, vol.8
, pp. e63862
-
-
Korecka, J.A.1
Van Kesteren, R.E.2
Blaas, E.3
Spitzer, S.O.4
Kamstra, J.H.5
Smit, A.B.6
Swaab, D.F.7
Verhaagen, J.8
Bossers, K.9
-
25
-
-
84893858665
-
Extracellular α-synuclein - A novel and crucial factor in lewy body diseases
-
Lee HJ, Bae EJ, Lee SJ Extracellular α-synuclein-a novel and crucial factor in Lewy body diseases. Nat Rev Neurol 2014; 10: 92-98.
-
(2014)
Nat Rev Neurol
, vol.10
, pp. 92-98
-
-
Lee, H.J.1
Bae, E.J.2
Lee, S.J.3
-
26
-
-
42749092078
-
Sphingosine 1-phos-phate induces mcl-1 upregulation and protects multiple myeloma cells against apoptosis
-
Li Q.F., Wu CT, Guo Q, Wang H., Wang LS. Sphingosine 1-phos-phate induces Mcl-1 upregulation and protects multiple myeloma cells against apoptosis. Biochem Biophys Res Commun 2008; 371: 159-162.
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 159-162
-
-
Li, Q.F.1
Wu, C.T.2
Guo, Q.3
Wang, H.4
Wang, L.S.5
-
27
-
-
17044371645
-
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of bcl-2 family members
-
Limaye V, Li X, Hahn C., Xia P, Berndt MC, Vadas M.A., Gamble JR. Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. Blood 2005; 105: 3169-3177.
-
(2005)
Blood
, vol.105
, pp. 3169-3177
-
-
Limaye, V.1
Li, X.2
Hahn, C.3
Xia, P.4
Berndt, M.C.5
Vadas, M.A.6
Gamble, J.R.7
-
28
-
-
0346059412
-
Glucocerebrosidase mutations in subjects with parkinsonism
-
Lwin A, Orvisky E, Goker-Alpan O, LaMarca M.E., Sidransky E. Glucocerebrosidase mutations in subjects with parkinsonism. Mol Genet Metab 2004; 81: 70-73.
-
(2004)
Mol Genet Metab
, vol.81
, pp. 70-73
-
-
Lwin, A.1
Orvisky, E.2
Goker-Alpan, O.3
LaMarca, M.E.4
Sidransky, E.5
-
29
-
-
27744547965
-
SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism
-
Maceyka M, Sankala H, Hait N.C., Le Stunf H, Liu H, Toman R., Collier C, Zhang M, Satin L.S., Merrill AH Jr, Milstien S, Spiegel S. SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. J Biol Chem 2005; 280: 37118-37129.
-
(2005)
J Biol Chem
, vol.280
, pp. 37118-37129
-
-
Maceyka, M.1
Sankala, H.2
Hait, N.C.3
Le Stunf, H.4
Liu, H.5
Toman, R.6
Collier, C.7
Zhang, M.8
Satin, L.S.9
Merrill, A.H.10
Milstien, S.11
Spiegel, S.12
-
30
-
-
84866114927
-
Ceramidesphingolipid signaling mediates tumor necrosis factor (TNF)-dependent toxicity via caspase signaling in dopami-nergic neurons
-
Martinez TN, Chen X, Bandyopadhyay S., Merrill AH, Tansey MG. Ceramidesphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopami-nergic neurons. Mol Neurodegener 2012; 7: 45.
-
(2012)
Mol Neurodegener
, vol.7
, pp. 45
-
-
Martinez, T.N.1
Chen, X.2
Bandyopadhyay, S.3
Merrill, A.H.4
Tansey, M.G.5
-
31
-
-
34250809874
-
Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated akt activation protects against in vivo myocardial ischemia-reperfu-sion injury
-
Means CK, Xiao C Y, Li Z, Zhang T., Omens JH, Ishii I, Chun J, Brown JH Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfu-sion injury. Am J Physiol Heart Circ Physiol 2007; 292: H2944-2951.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
, pp. H2944-2951
-
-
Means, C.K.1
Xiao, C.Y.2
Li, Z.3
Zhang, T.4
Omens, J.H.5
Ishii, I.6
Chun, J.7
Brown, J.H.8
-
32
-
-
0035793978
-
Stimulation of intracellular sphingo-sine-1-phosphate production by G-protein-coupled sphingo sine-1-phosphate receptors
-
Meyerzu Heringdorf D, Lass H, Kuchar I, Lipinski M, Alemany R, Rumenapp U, Jakobs KH. Stimulation of intracellular sphingo-sine-1-phosphate production by G-protein-coupled sphingo sine-1-phosphate receptors. Eur J Pharmacol 2001; 414: 145-154.
-
(2001)
Eur J Pharmacol
, vol.414
, pp. 145-154
-
-
Meyerzu Heringdorf, D.1
Lass, H.2
Kuchar, I.3
Lipinski, M.4
Alemany, R.5
Rumenapp, U.6
Jakobs, K.H.7
-
33
-
-
28544437478
-
Essential role for sphingosine kinases in neural and vascular development
-
Mizugishi K, Yamashita T, Olivera A., Miller G F, Spiegel S, Proia RL Essential role for sphingosine kinases in neural and vascular development. Mol Cell Biol 2005; 25: 11113-11121.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 11113-11121
-
-
Mizugishi, K.1
Yamashita, T.2
Olivera, A.3
Miller, G.F.4
Spiegel, S.5
Proia, R.L.6
-
34
-
-
84894528843
-
Reduced glucocerebro-sidase is associated with increased α-synuclein in sporadic parkinson's disease
-
Murphy KE, Gysbers AM, Abbott S.K., Tayebi N., Kim WS, Sidransky E, Cooper A, Garner B., Halliday GM. Reduced glucocerebro-sidase is associated with increased α-synuclein in sporadic Parkinson's disease. Brain 2014; 137: 834-848.
-
(2014)
Brain
, vol.137
, pp. 834-848
-
-
Murphy, K.E.1
Gysbers, A.M.2
Abbott, S.K.3
Tayebi, N.4
Kim, W.S.5
Sidransky, E.6
Cooper, A.7
Garner, B.8
Halliday, G.M.9
-
35
-
-
84867013405
-
Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway
-
Nakahara T, Iwase A, Nakamura T., Kondo M, Bayasula, Kobayashi H, Takikawa S, Manabe S, Goto M, Kotani T, Kikkawa F. Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway. Fertil Steril 2012; 98: 1001-1008.
-
(2012)
Fertil Steril
, vol.98
, pp. 1001-1008
-
-
Nakahara, T.1
Iwase, A.2
Nakamura, T.3
Kondo, M.4
Bayasula5
Kobayashi, H.6
Takikawa, S.7
Manabe, S.8
Goto, M.9
Kotani, T.10
Kikkawa, F.11
-
36
-
-
84886101285
-
Roles, regulation and inhibitors of sphingosine kinase 2
-
Neubauer HA, Pitson SM Roles, regulation and inhibitors of sphingosine kinase 2. FEBS J 2013; 280: 5317-5336.
-
(2013)
FEBS J
, vol.280
, pp. 5317-5336
-
-
Neubauer, H.A.1
Pitson, S.M.2
-
37
-
-
84868517918
-
Targeting the sphingosine kinase/sphin-gosine 1-phosphate pathway in disease: Review of sphingosine kinase inhibitors
-
Orr Gandy K.A., Obeid LM Targeting the sphingosine kinase/sphin-gosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors. Biochim Biophys Acta 2013; 1831: 157-166.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 157-166
-
-
Orr Gandy, K.A.1
Obeid, L.M.2
-
38
-
-
0026040772
-
Multiple forms of human dopamine beta-hydroxylase in SH-SY5Y neuroblastoma cells
-
Oyarce AM, Fleming PJ Multiple forms of human dopamine beta-hydroxylase in SH-SY5Y neuroblastoma cells. Arch Biochem Biophys 1991; 290: 503-510.
-
(1991)
Arch Biochem Biophys
, vol.290
, pp. 503-510
-
-
Oyarce, A.M.1
Fleming, P.J.2
-
39
-
-
0142105397
-
Activation of sphingosine kinase 1 by ERK1/2-me-diated phosphorylation
-
Pitson SM, Moretti PA, Zebol J.R., Lynn HE, Xia P, Vadas MA, Wattenberg BW Activation of sphingosine kinase 1 by ERK1/2-me-diated phosphorylation. EMBO J 2003; 22: 5491-5500.
-
(2003)
EMBO J
, vol.22
, pp. 5491-5500
-
-
Pitson, S.M.1
Moretti, P.A.2
Zebol, J.R.3
Lynn, H.E.4
Xia, P.5
Vadas, M.A.6
Wattenberg, B.W.7
-
40
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E., Ide SE, Dehejia A, Dutra A, Pike B, Root H., Rubenstein J, Boyer R, Stenroos E.S., Chandrasekharappa S, Athanassiadou A, Papapetropoulos T., Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997; 276: 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
41
-
-
84911007634
-
Sphingosine kinase 1 and sphingo sine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenyl-pyridinium (MPP+) in human dopaminergic neuronal cells
-
[Epub ahead of print]
-
Pyszko J, Strosznajder JB Sphingosine Kinase 1 and Sphingo sine-1-Phosphate in Oxidative Stress Evoked by 1-Methyl-4-Phenyl-pyridinium (MPP+) in Human Dopaminergic Neuronal Cells. Mol Neurobiol 2014; doi: 10.1007/s12035-013-8622-4 [Epub ahead of print].
-
(2014)
Mol Neurobiol
-
-
Pyszko, J.1
Strosznajder, J.B.2
-
42
-
-
0038734432
-
14-3-3 proteins in apoptosis
-
Rosenquist M. 14-3-3 proteins in apoptosis. Braz J Med Biol Res 2003; 36: 403-408.
-
(2003)
Braz J Med Biol Res
, vol.36
, pp. 403-408
-
-
Rosenquist, M.1
-
43
-
-
17644404054
-
Sphingosine 1-phosphate is involved in cyto-protective actions of calcitriol in human fibroblasts and enhances the intracellular bcl-2/Bax rheostat
-
Sauer B, Gonska H, Manggau M., Kim DS, Schraut C, Schäfer-Korting M, Kleuser B. Sphingosine 1-phosphate is involved in cyto-protective actions of calcitriol in human fibroblasts and enhances the intracellular Bcl-2/Bax rheostat. Pharmazie 2005; 60: 298-304.
-
(2005)
Pharmazie
, vol.60
, pp. 298-304
-
-
Sauer, B.1
Gonska, H.2
Manggau, M.3
Kim, D.S.4
Schraut, C.5
Schäfer-Korting, M.6
Kleuser, B.7
-
44
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
Spiegel S, Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 2003; 4: 397-407.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
45
-
-
30044452349
-
The mechanism of membrane targeting of human sphingosine kinase 1
-
Stahelin RV, Hwang JH, Kim J.H., Park ZY, Johnson KR, Obeid LM, Cho W. The mechanism of membrane targeting of human sphingosine kinase 1. J Biol Chem 2005; 280: 43030-43038.
-
(2005)
J Biol Chem
, vol.280
, pp. 43030-43038
-
-
Stahelin, R.V.1
Hwang, J.H.2
Kim, J.H.3
Park, Z.Y.4
Johnson, K.R.5
Obeid, L.M.6
Cho, W.7
-
46
-
-
33646117016
-
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor edg-3: The role of sphingosine kinase-1
-
Sukocheva OA, Wadham C, Holmes A., Albanese N, Verrier E, Feng F., Bernal A, Derian CK, Ullrich A, Vadas M.A., Xia P. Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1. J Cell Biol 2006; 173: 301-310.
-
(2006)
J Cell Biol
, vol.173
, pp. 301-310
-
-
Sukocheva, O.A.1
Wadham, C.2
Holmes, A.3
Albanese, N.4
Verrier, E.5
Feng, F.6
Bernal, A.7
Derian, C.K.8
Ullrich, A.9
Vadas, M.A.10
Xia, P.11
-
47
-
-
33744951972
-
The calmodulin binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane
-
Sutherland CM, Moretti PA, Hewitt N.M., Bagley CJ, Vadas MA, Pitson SM. The calmodulin binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane. J Biol Chem 2006; 281: 11693-11701.
-
(2006)
J Biol Chem
, vol.281
, pp. 11693-11701
-
-
Sutherland, C.M.1
Moretti, P.A.2
Hewitt, N.M.3
Bagley, C.J.4
Vadas, M.A.5
Pitson, S.M.6
-
48
-
-
61449258534
-
Critical role of bad phosphorylation by akt in cytostatic resistance of human bladder cancer cells
-
Szanto A, Bognar Z, Szigeti A., Szabo A, Farkas L, Gallyas F Jr. Critical role of bad phosphorylation by Akt in cytostatic resistance of human bladder cancer cells. Anticancer Res 2009; 29: 159-164.
-
(2009)
Anticancer Res
, vol.29
, pp. 159-164
-
-
Szanto, A.1
Bognar, Z.2
Szigeti, A.3
Szabo, A.4
Farkas, L.5
Gallyas, F.6
-
49
-
-
2442699980
-
Sphingosine-1-phosphate receptors: Receptor specificity versus functional redundancy
-
Taha TA, Argraves KM, Obeid LM Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy. Biochim Biophys Acta 2004; 1682: 48-55.
-
(2004)
Biochim Biophys Acta
, vol.1682
, pp. 48-55
-
-
Taha, T.A.1
Argraves, K.M.2
Obeid, L.M.3
-
50
-
-
46949104885
-
"Inside-out" signaling of sphingosine-1-phosphate: Therapeutic targets
-
Takabe K, Paugh SW, Milstien S, Spiegel S. "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol Rev 2008; 60: 181-195.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 181-195
-
-
Takabe, K.1
Paugh, S.W.2
Milstien, S.3
Spiegel, S.4
-
51
-
-
0028576861
-
Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihy-droxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system
-
Takahashi T, Deng Y, Maruyama W., Dostert P, Kawai M, Naoi M. Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihy-droxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system. J Neural Transm Gen Sect 1994; 98: 107-118.
-
(1994)
J Neural Transm Gen Sect
, vol.98
, pp. 107-118
-
-
Takahashi, T.1
Deng, Y.2
Maruyama, W.3
Dostert, P.4
Kawai, M.5
Naoi, M.6
-
52
-
-
79955770841
-
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate
-
Takasugi N, Sasaki T, Suzuki K., Osawa S, Isshiki H, Hori Y., Shimada N, Higo T, Yokoshima S., Fukuyama T, Lee VM, Trojanowski J.Q., Tomita T., Iwatsubo T. BACE1 activity is modulated by cell-associated sphingosine-1-phosphate. J Neurosci 2011; 31: 6850-6857.
-
(2011)
J Neurosci
, vol.31
, pp. 6850-6857
-
-
Takasugi, N.1
Sasaki, T.2
Suzuki, K.3
Osawa, S.4
Isshiki, H.5
Hori, Y.6
Shimada, N.7
Higo, T.8
Yokoshima, S.9
Fukuyama, T.10
Lee, V.M.11
Trojanowski, J.Q.12
Tomita, T.13
Iwatsubo, T.14
-
53
-
-
84867713914
-
Sphingosine-1-phosphate signaling in physiology and diseases
-
Takuwa Y, Okamoto Y, Yoshioka K., Takuwa N. Sphingosine-1-phosphate signaling in physiology and diseases. Biofactors 2012; 38: 329-337.
-
(2012)
Biofactors
, vol.38
, pp. 329-337
-
-
Takuwa, Y.1
Okamoto, Y.2
Yoshioka, K.3
Takuwa, N.4
-
54
-
-
70349503591
-
Biophysics of parkinson's disease: Structure and aggregation of alpha-synuclein
-
Uversky VN, Eliezer D. Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein. Curr Protein Pept Sci 2009; 10: 483-499.
-
(2009)
Curr Protein Pept Sci
, vol.10
, pp. 483-499
-
-
Uversky, V.N.1
Eliezer, D.2
-
55
-
-
84863009089
-
The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: Oxidative stress and the seesaw of cell survival and death
-
Van Brocklyn J.R., Williams JB The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death. Comp Biochem Physiol B Biochem Mol Biol 2012; 163: 26-36.
-
(2012)
Comp Biochem Physiol B Biochem Mol Biol
, vol.163
, pp. 26-36
-
-
Van Brocklyn, J.R.1
Williams, J.B.2
-
56
-
-
84875699450
-
Toxicity of extracellular secreted alpha-synuclein: Its role in nitrosative stress and neurodegeneration
-
Wilkaniec A, Strosznajder JB, Adamczyk A. Toxicity of extracellular secreted alpha-synuclein: Its role in nitrosative stress and neurodegeneration. Neurochem Int 2013; 62: 776-783.
-
(2013)
Neurochem Int
, vol.62
, pp. 776-783
-
-
Wilkaniec, A.1
Strosznajder, J.B.2
Adamczyk, A.3
-
57
-
-
69449100026
-
Alpha-synuclein knockdown attenuates MPP+ induced mito-chondrial dysfunction of SH-SY5Y cells
-
Wu F, Poon WS, Lu G, Wang A., Meng H, Feng L, Li Z., Liu S. Alpha-synuclein knockdown attenuates MPP+ induced mito-chondrial dysfunction of SH-SY5Y cells. Brain Res 2009; 1292: 173-179.
-
(2009)
Brain Res
, vol.1292
, pp. 173-179
-
-
Wu, F.1
Poon, W.S.2
Lu, G.3
Wang, A.4
Meng, H.5
Feng, L.6
Li, Z.7
Liu, S.8
-
58
-
-
0037040908
-
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling
-
Xia P, Wang L, Moretti P.A., Albanese N., Chai F, Pitson SM, D'Andrea RJ, Gamble JR, Vadas MA Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling. J Biol Chem 2002; 277: 7996-8003.
-
(2002)
J Biol Chem
, vol.277
, pp. 7996-8003
-
-
Xia, P.1
Wang, L.2
Moretti, P.A.3
Albanese, N.4
Chai, F.5
Pitson, S.M.6
D'Andrea, R.J.7
Gamble, J.R.8
Vadas, M.A.9
-
59
-
-
77951240010
-
SH-SY5Y human neuroblastoma cell line: In vitro cell model of dopaminergic neurons in parkinson's disease
-
Xie HR, Hu LS, Li GY SH-SY5Y human neuroblastoma cell line: in vitro cell model of dopaminergic neurons in Parkinson's disease. Chin Med J (Engl) 2010; 123: 1086-1092.
-
(2010)
Chin Med J (Engl)
, vol.123
, pp. 1086-1092
-
-
Xie, H.R.1
Hu, L.S.2
Li, G.Y.3
|