BH3-only molecule bim mediates ß-cell death in IRS2 deficiency

Diabetes

Volumn 63, Issue 10, 2014, Pages 3378-3387

  Ren, Decheng ^a   Sun, Juan ^a   Mao, Liqun ^a   Ye, Honggang ^a   Polonsky, Kenneth S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; CASPASE 3; GLUCOSE; INSULIN RECEPTOR SUBSTRATE 2; MESSENGER RNA; PROTEIN BCL XL; TRANSCRIPTION FACTOR FKHR; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; INSULIN RECEPTOR SUBSTRATE; IRS2 PROTEIN, MOUSE; MEMBRANE PROTEIN; ONCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GENE EXPRESSION; GENE REPRESSION; GLUCOSE TOLERANCE; INSULINOMA; MALE; MOLECULAR MECHANICS; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANIMAL; CELL COUNT; GENETICS; INSULIN RESISTANCE; KNOCKOUT MOUSE; METABOLISM; PANCREAS ISLET; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL COUNT; CELL DEATH; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84907495078     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1814     Document Type: Article

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