Ligation of TLR5 promotes myeloid cell infiltration and differentiation into mature osteoclasts in rheumatoid arthritis and experimental arthritis

Journal of Immunology

Volumn 193, Issue 8, 2014, Pages 3902-3913

  Kim, Seung Jae ^a   Chen, Zhenlong ^a   Chamberlain, Nathan D ^a   Essani, Abdul B ^a   Volin, Michael V ^b   Amin, M Asif ^c   Volkov, Suncica ^a   Gravallese, Ellen M ^d   Arami, Shiva ^a   Swedler, William ^a   Lane, Nancy E ^e   Mehta, Anjali ^a   Sweiss, Nadera ^a   Shahrara, Shiva ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UMASS MEMORIAL MEDICAL CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; FLAGELLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 5 ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AKT1 PROTEIN, MOUSE; COLLAGEN; OSTEOCLAST DIFFERENTIATION FACTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TNFRSF11A PROTEIN, MOUSE; TNFSF11 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE EROSION; BONE MARROW CELL; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MATURATION; CELL MIGRATION; CHEMOTAXIS; COLLAGEN-INDUCED ARTHRITIS; CONTROLLED STUDY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MONOCYTE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PATHOGENESIS; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CELL MOTION; CYTOLOGY; DBA MOUSE; DRUG EFFECTS; EXPERIMENTAL ARTHRITIS; IMMUNOLOGY; INFLAMMATION; MIDDLE AGED; MYELOID PROGENITOR CELL; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; ANTIBODIES; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; COLLAGEN; FEMALE; FLAGELLIN; HUMANS; INFLAMMATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MIDDLE AGED; MONOCYTES; MYELOID PROGENITOR CELLS; NF-KAPPA B; OSTEOCLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; SYNOVIAL FLUID; TOLL-LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907494136     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302998     Document Type: Article

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