Lipopolysaccharide promotes the survival of osteoclasts via toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is different from that of macrophages

Journal of Immunology

Volumn 170, Issue 7, 2003, Pages 3688-3695

  Itoh, Kanami ^a   Udagawa, Nobuyuki ^b   Kobayashi, Kanichiro ^a   Suda, Koji ^a   Li, Xiaotong ^b   Takami, Masamichi ^a   Okahashi, Nobuo ^c   Nishihara, Tatsuji ^d   Takahashi, Naoyuki ^b  

^a SHOWA UNIVERSITY   (Japan)

^b MATSUMOTO DENTAL UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d KYUSHU DENTAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; IN VITRO STUDY; MACROPHAGE; MALE; MISSENSE MUTATION; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; STEM CELL;

EID: 0345772095     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.7.3688     Document Type: Article

References (56)

1. Lynn, W. A., and D. T. Golenbock. 1992. Lipopolysaccharide antagonists. Immunol. Today 13:271.
2. Ulevitch, R. J., and P. S. Tobias. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:437.
3. Lee, M. J., N. Ancellin, J. H. Paik, and M. J. Kluk. 2001. Lysophospholipidsreceptor revelations. Science 294:1875.
4. Wilson, M., K. Reddi, and B. Henderson. 1996. Cytokine-inducing components of periodontopathogenic bacteria. J. Periodontal Res. 31:393.
5. Nair, S. P., S. Meghji, M. Wilson, K. Reddi, P. White, and B. Henderson. 1996. Bacterially induced bone destruction: mechanisms and misconceptions. Infect. Immun. 64:2371.
6. Means, T. K., D. T. Golenbock, and M. J. Fenton. 2000. Structure and function of Toll-like receptor proteins. Life Sci. 68:241.
7. Imler, J. L., and J. A. Hoffmann. 2000. Toll and Toll-like proteins: an ancient family of receptors signaling infection. Rev. Immunogenet. 2:294.
8. Ulevitch, R. J. 2000. Molecular mechanisms of innate immunity. Immunol. Res. 21:49.
9. Takeda, K., and S. Akira. 2001. Roles of Toll-like receptors in innate immune responses. Genes Cells 6:733.
10. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431.
11. Poltorak, A., X. He, I. Smirnova, M. Y. Liu, C. V. Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, et al. 1998. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282:2085.
12. Qureshi, S. T., L. Lariviere, G. Leveque, S. Clermont, K. J. Moore, P. Gros, and D. Malo. 1999. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J. Exp. Med. 189:615.
13. Hoshino, K., H. Tsutsui, T. Kawai, K. Takeda, K. Nakanishi, Y. Takeda, and S. Akira. 1999. Generation of IL-18 receptor-deficient mice: evidence for IL-I receptor-related protein as an essential IL-18 binding receptor. J. Immunol. 162:3749.
14. Naito, A., S. Azuma, S. Tanaka, T. Miyazaki, S. Takaki, K. Takatsu, K. Nakao, K. Nakamura, M. Katsuki, T. Yamamoto, and J. Inoue. 1999. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells 4:353.
15. Romaga, M. A., W. C. Yeh, I. Sarosi, G. S. Duncan, C. Furlonger, A. Ho, S. Morony, C. Capparelli, G. Van, S. Kaufman, et al. 1999. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev. 13:1015.
16. Silverman, N., and T. Maniatis. 2001. NF-κB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15:2321.
17. Roodman, G. D. 1999. Cell biology of the osteoclast. Exp. Hematol. 27:1229.
18. Chambers, T. J. 2000. Regulation of the differentiation and function of osteoclasts. J. Pathol. 192:4.
19. Teitelbaum, S. L. 2000. Bone resorption by osteoclasts. Science 289:1504.
20. Suda, T., N. Takahashi, N. Udagawa, E. Jimi, M. T. Gillespie, and T. J. Martin. 1999. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr. Rev. 20:345.
21. Takahashi, N., T. Akatsu, N. Udagawa, T. Sasaki, A. Yamaguchi, J. M. Moseley, T. J. Martin, and T. Suda. 1988. Osteoblastic cells are involved in osteoclast formation. Endocrinology 123:2600.
22. Yoshida, H., S. Hayashi, T. Kunisada, M. Ogawa, S. Nishikawa, H. Okamura, T. Sudo, L. D. Shultz, and S. Nishikawa. 1990. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345:442.
23. Felix, R., M. G. Cecchini, and H. Fleisch. 1990. Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse. Endocrinology 127:2592.
24. Wong, B. R., J. Rho, J. Arron, E. Robinson, J. Orlinick, M. Chao, S. Kalachikov, E. Cayani, F. S. Bartlett III, W. N. Frankel, et al. 1997. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J. Biol. Chem. 272:25190.
25. Anderson, D. M., E. Maraskovsky, W. L. Billingsley, W. C. Dougall, M. E. Tometsko, E. R. Roux, M. C. Teepe, R. F. DuBose, D. Cosman, and L. Galibert. 1997. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390:175.
26. Yasuda, H., N. Shima, N. Nakagawa, K. Yamaguchi, M. Kinosaki, S. Mochizuki, A. Tomoyasu, K. Yano, M. Goto, A. Murakami, et al. 1998. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA 95:3597.
27. Lacey, D. L., E. Timms, H. L. Tan, M. J. Kelley, C. R. Dunstan, T. Burgess, R. Elliott, A. Colombero, G. Elliott, S. Scully, et al. 1998. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93:165.
28. Jimi, E., S. Akiyama, T. Tsurukai, N. Okahashi, K. Kobayashi, N. Udagawa, T. Nishihara, N. Takahashi, and T. Suda. 1999. Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. J. Immunol. 163:434.
29. Li, J., I. Sarosi, X. Q. Yan, S. Morony, C. Capparelli, H. L. Tan, S. McCabe, R. Elliott, S. Scully, G. Van, et al. 2000. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoctastogenesis and regulation of bone mass and calcium metabolism. Proc. Natl. Acad. Sci. USA 97:1566.
30. Shimonet, W. S., D. L. Lacey, C. R. Dunstan, M. Kelley, M. S. Chang, R. Luthy, H. Q. Nguyen, S. Wooden, L. Bennett, T. Boone, et al. 1997. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89:309.
31. Tsuda, E., M. Goto, S. Mochizuki, K. Yano, F. Kobayashi, T. Morinaga, and K. Higashio. 1997. Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. Biochem. Biophys. Res. Commun. 234:137.
32. Darnay, B. G., V. Haridas, J. Ni, P. A. Moore, and B. B. Aggarwal. 1998. Characterization of the intracellular domain of receptor activator of NF-κB (RANK): interaction with tumor necrosis factor receptor-associated factors and activation of NF-κB and c-Jun N-terminal kinase. J. Biol. Chem. 273:20551.
33. Wong, B. R., R. Josien, S. Y. Lee, M. Vologodskaia, R. M. Steinman, and Y. Choi. 1998. The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor. J. Biol. Chem. 273:28355.
34. Galibert, L., M. E. Tometsko, D. M. Anderson, D. Cosman, and W. C. Dougall. 1998. The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-κB, a member of the TNFR superfamily. J. Biol. Chem. 273:34120.
35. Kobayashi, N., Y. Kadono, A. Naito, K. Matsumoto, T. Yamamoto, S. Tanaka, and J. Inoue. 2001. Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO J. 20:1271.
36. Jimi, E., I. Nakamura, T. Ikebe, S. Akiyama, N. Takahashi, and T. Suda. 1998. Activation of NF-κB is involved in the survival of osteoclasts promoted by interleukin-1. J. Biol. Chem. 273:8799.
37. Jimi, E., I. Nakamura, L. T. Duong, T. Ikebe, N. Takahashi, G. A. Rodan, and T. Suda. 1999. Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells. Exp. Cell Res. 247:84.
38. Kobayashi, K., N. Takahashi, E. Jimi, N. Udagawa, M. Takami, S. Kotake, N. Nakagawa, M. Kinosaki, K. Yamaguchi, N. Shima, et al. 2000. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J. Exp. Med. 191:275.
39. Bradley, J. R., and J. S. Pober. 2001. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 20:6482.
40. Rothe, M., M. G. Pan, W. J. Henzel, T. M. Ayres, and D. V. Goeddel. 1995. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 87:1243.
41. Abu-Amer, Y., F. P. Ross, J. Edwards, and S. L. Teitelbaum. 1997. Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor. J. Clin. Invest. 100:1557.
42. Koga, T., T. Nishihara, T. Fujiwara, T. Nisizawa, N. Okahashi, T. Noguchi, and S. Hamada. 1985. Biochemical and immunobiological properties of lipopolysaccharide (LPS) from Bacteroides gingivalis and comparison with LPS from Escherichia coli. Infect. Immun. 47:638.
43. 3 in osteoclast differentiation and function. Methods Emzymol. 282:223.
44. Takahashi, N., N. Udagawa, S. Tanaka, H. Murakami, I. Owan, T. Tamura, and T. Suda. 1994. Postmitotic osteoclast precursors are mononuclear cells which express macrophage-associated phenotypes. Dev. Biol. 163:212.
45. 3 in osteoclast-like multinucleated cells formed from mouse bone marrow cells. Endocrinology 123:1504.
46. Athanasou, N. A., and J. Quinn. 1990. Immunophenotypic differences between osteoclasts and macrophage polykaryons: immunohistological distinction and implications for osteoclast ontogeny and function. J. Clin. Pathol. 43:997.
47. Purton, L. E., M. Y. Lee, and B. Torok-Storb. 1996. Normal human peripheral blood mononuclear cells mobilized with granulocyte colony- stimulating factor have increased osteoclastogenic potential compared to nonmobilized blood. Blood 87:1802.
48. Fuller, K., J. M. Owens, C. J. Jagger, A. Wilson, R. Moss, and T. J. Chambers. 1993. Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts. J. Exp. Med. 178:1733.
49. Suda, K., J. T. Woo, M. Takami, P. M. Sexton, and K. Nagai. 2000. Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-α, IL-1, and RANKL. J. Cell. Physiol. 190:101.
50. Miyazaki, T., H. Katagiri, Y. Kanegae, H. Takayanagi, Y. Sawada, A. Yamamoto, M. P. Pando, T. Asano, I. M. Verma, H. Oda, et al. 2000. Reciprocal role of ERK and NF-κB pathways in survival and activation of osteoclasts. J. Cell Biol. 148:333.
51. Li, X., N. Udagawa, K. Itoh, K. Suda, Y. Murase, T. Nishihara, T. Suda, and N. Takahashi. 2002. p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function. Endocrinology 143:3105.
52. Wang, X. M., S. F. Yu, and Z. P. Yang. 2000. Apoptosis of osteoclast-like cells induced by alendronate is related to Fas gene expression. Chin. J. Dent. Res. 3:26.
53. Antonsson, B. 2001. Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion. Cell Tissue Res. 306:347.
54. Jimi, E., S. Akiyama, T. Tsurukai, K. Okahashi, K. Kobayashi, N. Udagawa, T. Nishihara, N. Takahashi, and T. Suda. 1999. Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. J. Immunol. 163:434.
55. Kikkawa, I., S. Saito, K. Tominaga, Y. Hoshino, Y. Ooi, and M. Nakano. 1998. Lipopolysaccharide stimulates the production of tumor necrosis factor-a and expression of inducible nitric oxide synthase by osteoclasts in murine bone marrow cell culture. Microbiol. Immunol. 42:591.
56. Roodman, G. D., N. Kurihara, Y. Ohsaki, A. Kukita, D. Hosking, A. Demulder, J. F. Smith, and F. R. Singer. 1992. Interleukin 6: a potential autocrine/paracrine factor in Paget's disease of bone. J. Clin. Invest. 89:46.