Stimulation of osteoclast formation by inflammatory synovial fluid

Virchows Archiv

Volumn 449, Issue 1, 2006, Pages 69-77

  Adamopoulos, Iannis E ^a,d   Danks, Lynett ^a   Itonaga, Ichiro ^b   Locklin, Rachel M ^a   Sabokbar, Afsie ^a   Ferguson, David J P ^c   Athanasou, Nicholas A ^d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b OITA UNIVERSITY   (Japan)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d NUFFIELD ORTHOPAEDIC CENTRE   (United Kingdom)

Author keywords

Crystal; Osteoclast; Pyrophosphate; Rheumatoid arthritis; Synovial fluid

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; COLONY STIMULATING FACTOR 1; CYTOKINE; GROWTH FACTOR; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; TUMOR NECROSIS FACTOR ALPHA; VITRONECTIN RECEPTOR;

ADULT; ARTHRITIS; ARTHROPATHY; ARTICLE; CELL DIFFERENTIATION; CLINICAL ARTICLE; FEMALE; HEMATOPOIESIS; HUMAN; HUMAN TISSUE; INFLAMMATION; INFLAMMATORY CELL; MALE; MONOCYTE; OSTEOARTHRITIS; OSTEOCLAST; OSTEOCLAST FORMATION; OSTEOCLASTOGENESIS; OSTEOLYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PYROPHOSPHATE ARTHROPATHY; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

ACID PHOSPHATASE; AGED; ARTHRITIS; BONE RESORPTION; CELL DIFFERENTIATION; CELLS, CULTURED; FEMALE; HUMANS; INTEGRIN ALPHAVBETA3; ISOENZYMES; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; OSTEOCLASTS; SYNOVIAL FLUID;

EID: 33745605755     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-006-0200-y     Document Type: Article

References (42)

1. Adamopoulos IE, Sabokbar A, Wordsworth BP, Carr A, Ferguson DJ, Athanasou NA (2006) Synovial fluid macrophages are capable of osteoclast formation and resorption. J Pathol 208:35-43
2. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS et al (1998) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-24
3. Aruffo A, Stamenkovic I, Melnick M, Underhill CB, Seed B (1990) CD44 is the principal cell surface receptor for hyaluronate. Cell 61:1303-13
4. Athanasou NA (1996) Cellular biology of bone-resorbing cells. J Bone Joint Surg Am 78:1096-112
5. Athanasou NA, Quinn J (1990) Immunophenotypic differences between osteoclasts and macrophage polykaryons: immunohistological distinction and implications for osteoclast ontogeny and function. J Clin Pathol 43:997-1003
6. Athanasou NA, Quinn J, Ferguson DJ, McGee JO (1991) Bone resorption by macrophage polykaryons of giant cell tumour of tendon sheath. Br J Cancer 63:527-533
7. Athanasou NA, Quinn J, Bulstrode CJ (1992) Resorption of bone by inflammatory cells derived from the joint capsule of hip arthroplasties. J Bone Joint Surg Br 74:57-62
8. Azuma Y, Kaji K, Katogi R, Takeshita S, Kudo A (2000) Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts. J Biol Chem 275:4858-4864
9. Darling JM, Goldring SR, Harada Y, Handel ML, Glowacki J, Gravallese EM (1997) Multinucleated cells in pigmented villonodular synovitis and giant cell tumor of tendon sheath express features of osteoclasts. Am J Pathol 150:1383-1393
10. Davies J, Warwick J, Totty N, Philp R, Helfrich M, Horton M (1989) The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor. J Cell Biol 109:1817-1826
11. Feldmann M, Brennan FM, Maini RN (1996) Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 14:397-440
12. Freemont A, Denton J (1991) Atlas of synovial fluid cytopathology. Kluwer Academic Publishers, Boston
13. Fujikawa Y, Quinn JM, Sabokbar A, McGee JO, Athanasou NA (1996) The human osteoclast precursor circulates in the monocyte fraction. Endocrinology 137:4058-4060
14. Fujikawa Y, Sabokbar A, Neale S, Athanasou NA (1996) Human osteoclast formation and bone resorption by monocytes and synovial macrophages in rheumatoid arthritis. Ann Rheum Dis 55:816-822
15. Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S (1999) Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone 25:255-259
16. Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Boyle WJ, Riggs BL (2000) The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 15:2-12
17. Itonaga I, Fujikawa Y, Sabokbar A, Murray DW, Athanasou NA (2000) Rheumatoid arthritis synovial macrophage-osteoclast differentiation is osteoprotegerin ligand-dependent. J Pathol 192:97-104
18. Itonaga I, Schulze E, Burge PD, Gibbons CL, Ferguson D, Athanasou NA (2002) Phenotypic characterization of mononuclear and multinucleated cells of giant cell reparative granuloma of small bones. J Pathol 198:30-36
19. Kania JR, Kehat-Stadler T, Kupfer SR (1997) CD44 antibodies inhibit osteoclast formation. J Bone Miner Res 12:1155-1164
20. Knapp W, Dorken B, Gilks WR, Rieber EP, Schmidt RE, Stein H, von dem Borne AEGK (1989) Leukocyte typing IV: white cell differentiation antigen. Oxford University Press, New York
21. Kobayashi K, Takahashi N, Jimi E, Udagawa N, Takami M, Kotake S, Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Morinaga T, Higashio K, Martin TJ, Suda T (2000) Tumor necrosis factor {alpha} stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med 191:275-286
22. Kotake S, Udagawa N, Hakoda M, Mogi M, Yano K, Tsuda E, Takahashi K, Furuya T, Ishiyama S, Kim KJ, Saito S, Nishikawa T, Takahashi N, Togari A, Tomatsu T, Suda T, Kamatani N (2001) Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum 44:1003-1012
23. Krenn V, Morawietz L, Haupl T, Neidel J, Petersen I, Konig A (2002) Grading of chronic synovitis - a histopathological grading system for molecular and diagnostic pathology. Pathol Res Pract 198(5):317-325
24. Kudo O, Fujikawa Y, Itonaga I, Sabokbar A, Torisu T, Athanasou NA (2002) Proinflammatory cytokine (TNFalpha/IL-1alpha) induction of human osteoclast formation. J Pathol 198:220-227
25. Kudo O, Sabokbar A, Pocock A, Itonaga I, Fujikawa Y, Athanasou NA (2003) Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism. Bone 32:1-7
26. Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, Elliott R, Colombero A, Elliott G, Scully S, Hsu H, Sullivan J, Hawkins N, Davy E, Capparelli C, Eli A, Qian YX, Kaufman S, Sarosi I, Shalhoub V, Senaldi G, Guo J, Delaney J, Boyle WJ (1998) Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93:165-176
27. Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL (2000) TNF-[alpha] induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 106:1481-1488
28. Lettesjo H, Nordstrom E, Strom H, Nilsson B, Glinghammar B, Dahlstedt L, Moller E (1998) Synovial fluid cytokines in patients with rheumatoid arthritis or other arthritic lesions. Scand J Immunol 48:286-292
29. McCarty D (1993) Synovial fluid. In: McCarty D, Koopman WJ (eds) Arthritis and allied conditions. Lea & Febiger, Philadelphia
30. Minkin C (1982) Bone acid phosphatase: tartrate-resistant acid phosphatase as a marker of osteoclast function. Calcif Tissue Int 34:285-290
31. Neale SD, Kristelly R, Gundle R, Quinn JM, Athanasou NA (1997) Giant cells in pigmented villo nodular synovitis express an osteoclast phenotype. J Clin Pathol 50:605-608
32. Partsch G, Steiner G, Leeb BF, Dunky A, Broll H, Smolen JS (1997) Highly increased levels of tumor necrosis factor-alpha and other proinflammatory cytokines in psoriatic arthritis synovial fluid. J Rheumatol 24:518-523
33. Quinn JM, Elliott J, Gillespie MT, Martin TJ (1998) A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology 139:4424-4427
34. Quinn JM, Whitty GA, Byrne RJ, Gillespie MT, Hamilton JA (2002) The generation of highly enriched osteoclast-lineage cell populations. Bone 30:164-170
35. Sabokbar A, Fujikawa Y, Neale S, Murray DW, Athanasou NA (1997) Human arthroplasty derived macrophages differentiate into osteoclastic bone resorbing cells. Ann Rheum Dis 56:414-420
36. Shigeyama Y, Pap T, Kunzler P, Simmen BR, Gay RE, Gay S (2000) Expression of osteoclast differentiation factor in rheumatoid arthritis. Arthritis Rheum 43:2523-2530
37. Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Luthy R, Nguyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliott R, Colombero A, Tan HL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L, Hughes TM, Hill D, Pattison W, Campbell P, Boyle WJ et al (1997) Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89:309-319
38. Smith JB, Bocchieri MH, Smith JB Jr, Sherbin-Allen L, Abruzzo JL (1990) Colony stimulating factor occurs in both inflammatory and noninflammatory synovial fluids. Rheumatol Int 10:131-134
39. Sterling H, Saginario C, Vignery A (1998) CD44 occupancy prevents macrophage multinucleation. J Cell Biol 143:837-847
40. Takayanagi H, Iizuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, Koshihara Y, Oda H, Nakamura K, Tanaka S (2000) Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 43:259-269
41. Vignery A (2000) Osteoclasts and giant cells: macrophage-macrophage fusion mechanism. Int J Exp Pathol 81:291-304
42. Yanni G, Whelan A, Feighery C, Bresnihan B (1994) Synovial tissue macrophages and joint erosion in rheumatoid arthritis. Ann Rheum Dis 53:39-44