Endotoxin-induced migration of monocytes and PECAM-1 phosphorylation are abrogated by PAF receptor antagonists

American Journal of Physiology - Endocrinology and Metabolism

Volumn 275, Issue 3 38-3, 1998, Pages

  Shen, Yamin ^a   Sultana, Chand ^a   Arditi, Moshe ^a   Kim, Kwang Sik ^a   Kalra, Vijay K ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Diapedesis; Endothelial cells; Lipopolysaccharide; Platelet endothelial cell adhesion molecule 1; Platelet activating factor; Transendothelial migration

Indexed keywords

ANTIBODY; CD31 ANTIGEN; ENDOTOXIN; MESSENGER RNA; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

ARTICLE; BACTERIAL INFECTION; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MONOCYTE; NORTHERN BLOTTING; PHOSPHORYLATION; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

EID: 0031720606     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1998.275.3.e479     Document Type: Article

References (30)

1. Albelda, S. M., W. A. Muller, C. A. Buck, and P. J. Newman. Molecular and cellular properties of PECAM-1 (endoCAM/ CD31): a novel vascular cell-cell adhesion molecule. J. Cell Biol. 114: 1059-1068, 1991.
2. Anderson, B. O., D. D. Bensard, and A. H. Harken. The role of platelet activating factor and its antagonists in shock, sepsis and multiple organ failure. Surg. Gynecol. Obstet. 172: 415-424, 1991.
3. Arditi, M., K. R. Manogue, M. Caplan, and R. Yogev. Cerebrospinal fluid cachectin/tumor necrosis factor-α and platelet-activating factor concentrations and severity of bacterial meningitis in children. J. Infect. Dis. 162: 139-147, 1990.
4. Arditi, M., J. Zhou, R. Dorio, G. W. Rong, S. M. Goyert, and K. S. Kim. Endotoxin-mediated endothelial cell injury and activation: role of soluble CD14. Infect. Immunol. 61: 3149-3156, 1993.
5. Ayalon, O., H. Sabanai, M. G. Lampugnani, E. Dejana, and B. Geiger. Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells. J. Cell Biol. 126: 247-258, 1994.
6. Bevilacqua, M. P. Endothelial-leukocyte adhesion molecules. Annu. Rev. Immunol. 11: 767-804, 1993.
7. Butcher, E. C. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67: 1033-1036, 1991.
8. Camussi, G., F. Mariano, L. Biancone, A. de Martino, B. Bussolati, G. Montrucchio, and P. S. Tobias. Lipopolysaccharide binding protein and CD14 modulate the synthesis of platelet-activating factor by human monocytes and mesangial and endothelial cells stimulated with lipopolysaccharide. J. Immunol. 155: 316-324, 1995.
9. Doebber, T. W., M. S. Wu, J. C. Robbing, B. M. Choy, M. N. Chang, and T. Y. Shen. Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. Studies with PAF-receptor antagonist kadsurenone. Biochem. Biophys. Res. Commun. 127: 799-808, 1985.
10. Frey, E. A., D. S. Miller, T. G. Jahr, A. Sundan, V. Bazil, T. Espevik, B. B. Finlay, and S. D. Wright. Soluble CD14 participates in the response of cells to lipopolysaccharide. J. Exp. Med. 176: 1665-1671, 1992.
11. Hill, M. E., I. N. Bird, R. H. Daniels, M. A. Elmore, and M. J. Finnen. Endothelial cell-associated platelet-activating factor primes neutrophils for enhanced superoxide production and arachidonic acid release during adhesion to but not transmigration across IL-1 β-treated endothelial monolayers. J. Immunol. 153: 3673-3683, 1994.
12. Issekutz, A. C., and N. Lopes. Endotoxin activation of endothelium for polymorphonuclear leucocyte transendothelial migration and modulation by interferon-gamma. Immunology 79: 600-607, 1993.
13. Jaffe, S., P. D. Oliver, S. M. Farooqui, P. L. Novak, N. Sorgente, and V. K. Kalra. Separation of luminal and abluminal membrane enriched domains from cultured bovine aortic endothelial cells: monoclonal antibodies specific for endothelial cell plasma membranes. Biochim. Biophys. Acta 898: 37-52, 1987.
14. Kalra, V. K., R. Banerjee, and N. Sorgente. Heterotypic and homotypic cell-cell adhesion molecules in endothelial cells. Biotechnol. Appl. Biochem. 12: 579-585, 1990.
15. Kalra, V. K., Y. Shen, C. Sultana, and V. Rattan. Hypoxia induces PECAM-1 phosphorylation and transendothelial migration of monocytes. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H2025-H2034, 1996.
16. Kalra, V. K., Y. Ying, K. Deemer, R. Natarajan, J. L. Nadler, and T. D. Coates. Mechanism of cigarette smoke condensate induced adhesion of human monocytes to cultured endothelial cells. J. Cell. Physiol. 160: 154-162, 1994.
17. Kazakoff, P. W., T. R. McGuire, E. B. Hoie, M. Cano, and P. L. Iversen. An in vitro model for endothelial permeability: assessment of monolayer integrity. In Vitro Cell Dev. Biol. Anim. 31: 846-852, 1995.
18. Languino, L. R., A. Duperray, K. J. Joganic, M. Fornaro, G. B. Thornton, and D. C. Altieri. Regulation of leukocyte-endothelium interaction and leukocyte transendothelial migration by intercellular adhesion molecule 1-fibrinogen recognition. Proc. Natl. Acad. Sci. USA 92: 1505-1509, 1995.
19. Meerschaert, J., and M. B. Furie. The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium. J. Immunol. 154: 4099-4112, 1995.
20. Morrison, D. C., and J. L. Ryan. Endotoxins and disease mechanisms. Annu. Rev. Med. 38: 417-432, 1987.
21. Muller, W. A., S. A. Weigl, X. Deng, and D. M. Phillips. PECAM-1 is required for transendothelial migration of leukocytes. J. Exp. Med. 178: 449-460, 1993.
22. Murohara, T., J. A. Delyani, S. M. Albelda, and A. M. Lefer. Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury in cats. J. Immunol. 156: 3550-3557, 1996.
23. Newman, P. J., C. A. Hillery, R. Albrecht, L. V. Parise, M. C. Berndt, A. V. Mazurov, L. C. Dunlop, J. Zhang, and S. E. Rittenhouse. Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution. J. Cell Biol. 119: 239-246, 1992.
24. Parrillo, J. E. Pathogenetic mechanisms of septic shock. N. Engl. J. Med. 328: 1471-1477, 1993.
25. Shen, Y., V. Rattan, C. Sultana, and V. K. Kalra. Cigarette smoke condensate-induced adhesion molecule expression and transendothelial migration of monocytes. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H1624-H1633, 1996.
26. Singer, K. L., B. R. Stevenson, P. L. Woo, and G. L. Firestone. Relationship of serine/threonine phosphorylation/dephosphorylation signaling to glucocorticoid regulation of tight junction permeability and ZO-1 distribution in nontransformed mammary epithelial cells. J. Biol. Chem. 269: 16108-16115, 1994.
27. Springer, T. A. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301-314, 1994.
28. Vaporciyan, A. A., H. M. DeLisser, H. C. Yan, I. I. Mendiguren, S. R. Thom, M. L. Jones, P.A. Ward, and S. M. Albelda. Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science 262: 1580-1582, 1993.
29. Wang, H., X. Tan, H. Chang, F. Gonzalez-Crussi, D. G. Remick, and W. Hsueh. Regulation of platelet-activating factor receptor gene expression in vivo by endotoxin, platelet-activating factor and endogenous tumour necrosis factor. Biochem. J. 322: 603-608, 1997.
30. Ye, R. D., E. R. Prossnitz, A. H. Zou, and C. G. Cochrane. Characterization of a human cDNA that encodes a functional receptor for platelet activating factor. Biochem. Biophys. Res. Commun. 180: 105-111, 1991.