Ligation of TLR7 by rheumatoid arthritis synovial fluid single strand RNA induces transcription of TNFα in monocytes

Annals of the Rheumatic Diseases

Volumn 72, Issue 3, 2013, Pages 418-426

  Chamberlain, Nathan D ^a   Kim, Seung Jae ^a   Vila, Olga M ^a   Volin, Michael V ^b   Volkov, Suncica ^a   Pope, Richard M ^c   Arami, Shiva ^a   Mandelin II, Arthur M ^c   Shahrara, Shiva ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; DISEASE MODIFYING ANTIRHEUMATIC DRUG; HYDROXYCHLOROQUINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEFLUNOMIDE; METHOTREXATE; MINOCYCLINE; PHOSPHATIDYLINOSITOL 3 KINASE; PREDNISONE; RITUXIMAB; SALAZOSULFAPYRIDINE; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ADULT; ARTICLE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY SCORE; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; LIGAND BINDING; MACROPHAGE; MALE; MONOCYTE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; RHEUMATOID ARTHRITIS; RNA DEGRADATION; RNA TRANSCRIPTION; SYNOVIAL FLUID; SYNOVIUM; WESTERN BLOTTING;

ARTHRITIS, RHEUMATOID; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MONOCYTES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SYNOVIAL FLUID; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84873739004     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2011-201203     Document Type: Article

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