Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation

Immunology Letters

Volumn 110, Issue 1, 2007, Pages 54-64

  Kim, Kyoung Woon ^a   Cho, Mi La ^a   Lee, Sang Heon ^b   Oh, Hye Joa ^a   Kang, Chang Min ^a   Ju, Ji Hyeon ^a   Min, So Youn ^a   Cho, Young Gyu ^a   Park, Sung Hwan ^a   Kim, Ho Youn ^a  

^a The Catholic University of Korea   (South Korea)

^b Konkuk University Hospital   (South Korea)

Author keywords

Autoimmune arthritis; FLS; Osteoclastogenesis; RANKL; Toll like receptor

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CALCITONIN RECEPTOR; CATHEPSIN K; GELATINASE B; INTERLEUKIN 17; INTERLEUKIN 1BETA; LIGAND; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MONOCYTE; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; STIMULATION; SYNOVIOCYTE; UPREGULATION;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; FEMALE; FIBROBLASTS; HUMANS; IMMUNITY, NATURAL; MALE; MIDDLE AGED; OSTEOARTHRITIS; OSTEOCLASTS; RANK LIGAND; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 34247881945     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2007.03.004     Document Type: Article

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