Anti-CXCL5 therapy ameliorates IL-17-induced arthritis by decreasing joint vascularization

Angiogenesis

Volumn 14, Issue 4, 2011, Pages 443-455

  Pickens, Sarah R ^a   Chamberlain, Nathan D ^a   Volin, Michael V ^b   Gonzalez, Mark ^a   Pope, Richard M ^c   Mandelin II, Arthur M ^c   Kolls, Jay K ^d   Shahrara, Shiva ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b MIDWESTERN UNIVERSITY   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; CXCL1; CXCL5; IL 17 induced arthritis

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIRHEUMATIC AGENT; CXCL1 ANTIBODY; CXCL1 CHEMOKINE; CXCL5 ANTIBODY; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FIBROBLAST GROWTH FACTOR 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; INTERLEUKIN 17; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE EROSION; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE SEVERITY; DOWN REGULATION; DRUG EFFECT; HUMAN; HUMAN CELL; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCORING SYSTEM; SIGNAL TRANSDUCTION; SYNOVIUM;

ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES, NEUTRALIZING; ARTHRITIS, RHEUMATOID; BLOTTING, WESTERN; CELLS, CULTURED; CHEMOKINE CXCL1; CHEMOKINE CXCL5; CHEMOTAXIS; CYTOKINES; DIMETHYL SULFOXIDE; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-17; MICE; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE;

MUS;

EID: 84855202439     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-011-9227-z     Document Type: Article

References (49)

1. GS Firestein 2003 Evolving concepts of rheumatoid arthritis Nature 423 356 361 12748655 1:CAS:528:DC%2BD3sXjs1ynu7c%3D 10.1038/nature01661 (Pubitemid 40852711)
2. E Lubberts MI Koenders B Oppers-Walgreen, et al. 2004 Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion Arthritis Rheum 50 650 659 14872510 1:CAS:528: DC%2BD2cXhvFeiu70%3D 10.1002/art.20001 (Pubitemid 38198849)
3. MI Koenders E Lubberts FA van de Loo, et al. 2006 Interleukin-17 acts independently of TNF-alpha under arthritic conditions J Immunol 176 6262 6269 16670337 1:CAS:528:DC%2BD28XktVWnsrs%3D
4. E Lubberts LA Joosten B Oppers, et al. 2001 IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis J Immunol 167 1004 1013 11441109 1:CAS:528:DC%2BD3MXotFWktLk%3D (Pubitemid 32660858)
5. MI Koenders E Lubberts B Oppers-Walgreen, et al. 2005 Induction of cartilage damage by overexpression of T cell interleukin-17A in experimental arthritis in mice deficient in interleukin-1 Arthritis Rheum 52 975 983 15751058 1:CAS:528:DC%2BD2MXjtVGjur8%3D 10.1002/art.20885 (Pubitemid 40365122)
6. S Nakae A Nambu K Sudo, et al. 2003 Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice J Immunol 171 6173 6177 14634133 1:CAS:528:DC%2BD3sXptFOktrg%3D (Pubitemid 37467240)
7. P Ye FH Rodriguez S Kanaly, et al. 2001 Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense J Exp Med 194 519 527 11514607 1:CAS:528:DC%2BD3MXmt1egu7o%3D 10.1084/jem.194.4.519 (Pubitemid 32835046)
8. P Schwarzenberger V La Russa A Miller, et al. 1998 IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines J Immunol 161 6383 6389 9834129 1:CAS:528:DyaK1cXnslGjsrc%3D (Pubitemid 28536015)
9. SB Forlow JR Schurr JK Kolls, et al. 2001 Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice Blood 98 3309 3314 11719368 1:CAS:528:DC%2BD3MXovVSgsL8%3D 10.1182/blood.V98.12.3309
10. F Luzza T Parrello G Monteleone, et al. 2000 Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa J Immunol 165 5332 5337 11046068 1:CAS:528:DC%2BD3cXnvVOntLo%3D
11. S Zrioual ML Toh A Tournadre, et al. 2008 IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR + CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood J Immunol 180 655 663 18097068 1:CAS:528:DC%2BD2sXhsVGjurbL
12. F Shen SL Gaffen 2008 Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy Cytokine 41 92 104 18178098 1:CAS:528:DC%2BD1cXhsl2gtL4%3D 10.1016/j.cyto.2007.11.013
13. MJ Ruddy F Shen JB Smith, et al. 2004 Interleukin-17 regulates expression of the CXC chemokine LIX/CXCL5 in osteoblasts: implications for inflammation and neutrophil recruitment J Leukoc Biol 76 135 144 15107456 1:CAS:528:DC%2BD2cXlsVOis7c%3D 10.1189/jlb.0204065 (Pubitemid 38857180)
14. J Witowski K Pawlaczyk A Breborowicz, et al. 2000 IL-17 stimulates intraperitoneal neutrophil infiltration through the release of GRO alpha chemokine from mesothelial cells J Immunol 165 5814 5821 11067941 1:CAS:528:DC%2BD3cXot1Grtro%3D
15. Z Szekanecz A Pakozdi A Szentpetery, et al. 2009 Chemokines and angiogenesis in rheumatoid arthritis Front Biosci (Elite Ed) 1 44 51
16. Z Szekanecz T Besenyei G Paragh, et al. 2009 New insights in synovial angiogenesis Joint Bone Spine 77 13 19 20022538 10.1016/j.jbspin.2009.05.011
17. AE Koch SL Kunkel LA Harlow, et al. 1994 Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis J Clin Invest 94 1012 1018 8083342 1:CAS:528:DyaK2cXlslOmtrY%3D 10.1172/JCI117414 (Pubitemid 24286441)
18. N Reich C Beyer K Gelse, et al. 2011 Microparticles stimulate angiogenesis by inducing ELR(+) CXC-chemokines in synovial fibroblasts J Cell Mol Med 15 756 762 20219013 1:CAS:528:DC%2BC3MXmslWlsrk%3D 10.1111/j.1582-4934. 2010.01051.x
19. AE Koch MV Volin JM Woods, et al. 2001 Regulation of angiogenesis by the C-X-C chemokines interleukin-8 and Epithelial Neutrophil Activating Peptide 78 in the rheumatoid joint Arthritis Rheum 44 31 40 11212173 1:CAS:528: DC%2BD3MXht1yitrk%3D 10.1002/1529-0131(200101)44:1<31::AID-ANR5>3.0.CO;2-4 (Pubitemid 32113115)
20. PL Podolin BJ Bolognese JJ Foley, et al. 2002 A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit J Immunol 169 6435 6444 12444152 1:CAS:528:DC%2BD38Xpt1Kls7s%3D (Pubitemid 36903493)
21. T Kagari D Tanaka H Doi, et al. 2007 Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice Eur J Immunol 37 2753 2763 17823985 1:CAS:528:DC%2BD2sXht1ersrrN 10.1002/eji.200737313 (Pubitemid 47578294)
22. FM Coelho V Pinho FA Amaral, et al. 2008 The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature Arthritis Rheum 58 2329 2337 18668539 10.1002/art.23622
23. SR Pickens MV Volin AM Mandelin II, et al. 2010 IL-17 contributes to angiogenesis in rheumatoid arthritis J Immunol 184 3233 3241 20173024 1:CAS:528:DC%2BC3cXis1yit7Y%3D 10.4049/jimmunol.0903271
24. FC Arnett SM Edworthy DA Bloch, et al. 1988 The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 315 324 3358796 1:STN:280:DyaL1c7pt1Ohsg%3D%3D 10.1002/art.1780310302 (Pubitemid 18091653)
25. S Shahrara HP Castro-Rueda GK Haines, et al. 2007 Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues Arthritis Res Ther 9 R112 17963503 10.1186/ar2318 (Pubitemid 350286462)
26. S Shahrara CC Park V Temkin, et al. 2006 RANTES modulates TLR4-induced cytokine secretion in human peripheral blood monocytes J Immunol 177 5077 5087 17015691 1:CAS:528:DC%2BD28XhtVansrrE (Pubitemid 44527578)
27. S Shahrara SR Pickens AM Mandelin II, et al. 2010 IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction J Immunol 184 4479 4487 20228199 1:CAS:528:DC%2BC3cXkt1Wqtb0%3D 10.4049/jimmunol.0901942
28. S Shahrara SR Pickens A Dorfleutner, et al. 2009 IL-17 induces monocyte migration in rheumatoid arthritis J Immunol 182 3884 3891 19265168 1:CAS:528:DC%2BD1MXis12ht78%3D 10.4049/jimmunol.0802246
29. S Shahrara Q Huang AM Mandelin II, et al. 2008 TH-17 cells in rheumatoid arthritis Arthritis Res Ther 10 R93 18710567 10.1186/ar2477
30. S Shahrara MV Volin MA Connors, et al. 2002 Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue Arthritis Res 4 201 208 12010571 1:CAS:528:DC%2BD38XjsVKjtL4%3D 10.1186/ar407 (Pubitemid 34460760)
31. S Shahrara AE Proudfoot JM Woods, et al. 2005 Amelioration of rat adjuvant-induced arthritis by Met-RANTES Arthritis Rheum 52 1907 1919 15934086 1:CAS:528:DC%2BD2MXlvFChu7g%3D 10.1002/art.21033 (Pubitemid 40852900)
32. S Shahrara AE Proudfoot CC Park, et al. 2008 Inhibition of monocyte chemoattractant protein-1 ameliorates rat adjuvant-induced arthritis J Immunol 180 3447 3456 18292571 1:CAS:528:DC%2BD1cXit1Okt78%3D
33. JC Scatizzi E Bickel J Hutcheson, et al. 2006 Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis Arthritis Rheum 54 3182 3193 17009248 1:CAS:528:DC%2BD28XhtFyqs7rK 10.1002/art.22133 (Pubitemid 44622089)
34. JH Ruth MV Volin GK Haines III, et al. 2001 Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis Arthritis Rheum 44 1568 1581 11465708 1:CAS:528:DC%2BD38Xkt1ar 10.1002/1529-0131(200107)44:7<1568::AID-ART280>3.0.CO;2-1 (Pubitemid 32642219)
35. AE Koch BJ Nickoloff J Holgersson, et al. 1994 4A11, a monoclonal antibody recognizing a novel antigen expressed on aberrant vascular endothelium. Upregulation in an in vivo model of contact dermatitis Am J Pathol 144 244 259 8311112 1:CAS:528:DyaK2cXjt1Wjs7g%3D (Pubitemid 24165946)
36. CC Park JC Morel MA Amin, et al. 2001 Evidence of IL-18 as a novel angiogenic mediator J Immunol 167 1644 1653 11466388 1:CAS:528: DC%2BD3MXls1WrsLg%3D (Pubitemid 32703167)
37. F Huang CY Kao S Wachi, et al. 2007 Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells J Immunol 179 6504 6513 17982039 1:CAS:528:DC%2BD2sXht1CrsrzE
38. A Kehlen K Thiele D Riemann, et al. 2002 Expression, modulation and signalling of IL-17 receptor in fibroblast-like synoviocytes of patients with rheumatoid arthritis Clin Exp Immunol 127 539 546 11966773 1:CAS:528: DC%2BD38XjvFCisrc%3D 10.1046/j.1365-2249.2002.01782.x (Pubitemid 34437828)
39. M Chabaud G Page P Miossec 2001 Enhancing Effect of IL-1, IL-17, and TNF-alpha on Macrophage Inflammatory Protein-3alpha Production in Rheumatoid Arthritis: regulation by Soluble Receptors and Th2 Cytokines J Immunol 167 6015 6020 11698482 1:CAS:528:DC%2BD3MXotlalsrg%3D (Pubitemid 33062800)
40. S Datta M Novotny PG Pavicic Jr, et al. 2010 IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence J Immunol 184 1484 1491 20042592 1:CAS:528:DC%2BC3cXhtVGit78%3D 10.4049/jimmunol.0902423
41. J Hartupee C Liu M Novotny, et al. 2007 IL-17 enhances chemokine gene expression through mRNA stabilization J Immunol 179 4135 4141 17785852 1:CAS:528:DC%2BD2sXpvFKltb4%3D
42. D Wang J Sai A Richmond 2003 Cell surface heparan sulfate participates in CXCL1-induced signaling Biochemistry 42 1071 1077 12549928 1:CAS:528: DC%2BD3sXitVGjsA%3D%3D 10.1021/bi026425a (Pubitemid 36159541)
43. G Yang DG Rosen Z Zhang, et al. 2006 The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis Proc Natl Acad Sci USA 103 16472 16477 17060621 1:CAS:528:DC%2BD28Xht1WmsLnN 10.1073/pnas.0605752103 (Pubitemid 44715220)
44. R Filipovic N Zecevic 2008 The effect of CXCL1 on human fetal oligodendrocyte progenitor cells Glia 56 1 15 17910053 10.1002/glia.20582 (Pubitemid 350172726)
45. B Chandrasekar PC Melby HM Sarau, et al. 2003 Chemokine-cytokine cross-talk. The ELR + CXC chemokine LIX (CXCL5) amplifies a proinflammatory cytokine response via a phosphatidylinositol 3-kinase-NF-kappa B pathway J Biol Chem 278 4675 4686 12468547 1:CAS:528:DC%2BD3sXhtVKlsr0%3D 10.1074/jbc. M207006200 (Pubitemid 36800967)
46. DF Smith E Galkina K Ley, et al. 2005 GRO family chemokines are specialized for monocyte arrest from flow Am J Physiol Heart Circ Physiol 289 H1976 H1984 15937099 1:CAS:528:DC%2BD2MXht1Cnt7bP 10.1152/ajpheart.00153.2005 (Pubitemid 41507347)
47. DV Jovanovic JA Di Battista J Martel-Pelletier, et al. 1998 IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages J Immunol 160 3513 3521 9531313 1:CAS:528:DyaK1cXitFWqsLs%3D (Pubitemid 28164746)
48. P Rathanaswami M Hachicha M Sadick, et al. 1993 Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts J Biol Chem 268 5834 5839 7680648 1:CAS:528:DyaK3sXhvV2rtrs%3D
49. T Nanki K Nagasaka K Hayashida, et al. 2001 Chemokines regulate IL-6 and IL-8 production by fibroblast-like synoviocytes from patients with rheumatoid arthritis J Immunol 167 5381 5385 11673556 1:CAS:528:DC%2BD3MXotVWjtrc%3D (Pubitemid 33009778)