SHIP1 regulates MSC numbers and their osteolineage commitment by limiting induction of the PI3K/Akt/β-catenin/Id2 axis

Stem Cells and Development

Volumn 23, Issue 19, 2014, Pages 2336-2351

  Iyer, Sonia ^a   Viernes, Dennis R ^b   Chisholm, John D ^b   Margulies, Bryan S ^a   Kerr, William G ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b SYRACUSE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; INHIBITOR OF DIFFERENTIATION 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE B; SRC HOMOLOGY 2 DOMAIN CONTAINING INOSITOL 5' PHOSPHATASE 1 PROTEIN; UNCLASSIFIED DRUG; CTNNB1 PROTEIN, MOUSE; INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE; PHOSPHATASE;

ADHERENT CELL; ADULT; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE GROWTH; BONE MASS; BONE MINERAL; CELL DIFFERENTIATION; COLONY FORMING UNIT F; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; IN VIVO STUDY; MALE; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOCLAST; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; C57BL MOUSE; CELL LINEAGE; CYTOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; BETA CATENIN; CELL LINEAGE; MESENCHYMAL STROMAL CELLS; MICE, INBRED C57BL; MICE, TRANSGENIC; OSTEOCLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84907429697     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2014.0122     Document Type: Article

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