Differential regulation of CXCL5 by FGF2 in osteoblastic and endothelial niche cells supports hematopoietic stem cell migration

Stem Cells and Development

Volumn 21, Issue 18, 2012, Pages 3391-3402

  Yoon, Kyung Ae ^a   Cho, Hye Sim ^b   Shin, Hong In ^a   Cho, Je Yoel ^c  

^a Kyungpook National University   (South Korea)

^b ProtAnBio Co   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FIBROBLAST GROWTH FACTOR 2;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIUM CELL; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STEM CELL NICHE;

ANIMALS; BONE MARROW; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINE; CELL MOVEMENT; CHEMOKINE CXCL12; CHEMOKINE CXCL5; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MICE; OSTEOBLASTS; STEM CELL NICHE;

EID: 84870854523     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0128     Document Type: Article

References (62)

1. Zhang J, C Niu, L Ye, H Huang, X He, WG Tong, J Ross, J Haug, T Johnson, et al. (2003). Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425:836-841.
2. Calvi LM, GB Adams, KW Weibrecht, JM Weber, DP Olson, MC Knight, RP Martin, E Schipani, P Divieti, et al. (2003). Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425:841846.
3. Kiel MJ and SJ Morrison. (2006). Maintaining hematopoietic stem cells in the vascular niche. Immunity 25:862-864.
4. Lane SW, DT Scadden and DG Gilliland. (2009). The leukemic stem cell niche: current concepts and therapeutic opportunities. Blood 114:1150-1157.
5. Raaijmakers MH, S Mukherjee, S Guo, S Zhang, T Kobayashi, JA Schoonmaker, BL Ebert, F Al-Shahrour, RP Hasser-jian, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 464:852-857.
6. Bikfalvi A, S Klein, G Pintucci and DB Rifkin. (1997). Biological roles of fibroblast growth factor-2. Endocr Rev 18:26-45.
7. Thisse B and C Thisse. (2005). Functions and regulations of fibroblast growth factor signaling during embryonic development. Dev Biol 287:390-402.
8. Nguyen M, H Watanabe, AE Budson, JP Richie, DF Hayes and J Folkman. (1994). Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers. J Natl Cancer Inst 86:356-361.
9. Aiuti A, IJ Webb, C Bleul, T Springer and JC Gutierrez-Ramos. (1997). The chemokine SDF-1 is a chemoattractant for human CD34 + hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34 + progenitors to peripheral blood. J Exp Med 185: 111-120.
10. Lataillade JJ, D Clay, C Dupuy, S Rigal, C Jasmin, P Bourin and MC Le Bousse-Kerdiles. (2000). Chemokine SDF-1 enhances circulating CD34 (+) cell proliferation in synergy with cytokines: possible role in progenitor survival. Blood 95:756-768.
11. Pelus LM and S Fukuda. (2006). Peripheral blood stem cell mobilization: the CXCR2 ligand GRObeta rapidly mobilizes hematopoietic stem cells with enhanced engraftment properties. Exp Hematol 34:1010-1020.
12. Christopherson KW, 2nd, G Hangoc, CR Mantel and HE Broxmeyer. (2004). Modulation of hematopoietic stem cell homing and engraftment by CD26. Science 305:1000-1003.
13. Kobayashi H, JM Butler, R O'Donnell, M Kobayashi, BS Ding, B Bonner, VK Chiu, DJ Nolan, K Shido, L Benjamin and S Rafii. Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nat Cell Biol 12:1046-1056.
14. Mayack SR and AJ Wagers. (2008). Osteolineage niche cells initiate hematopoietic stem cell mobilization. Blood 112: 519-531.
15. Balduino A, SP Hurtado, P Frazao, CM Takiya, LM Alves, LE Nasciutti, MC El-Cheikh and R Borojevic. (2005). Bone marrow subendosteal microenvironment harbours functionally distinct haemosupportive stromal cell populations. Cell Tissue Res 319:255-266.
16. Chitteti BR, YH Cheng, DA Streicher, S Rodriguez-Rodriguez, N Carlesso, EF Srour and MA Kacena. Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function. J Cell Biochem 111:284-294.
17. Nilsson SK, HM Johnston, GA Whitty, B Williams, RJ Webb, DT Denhardt, I Bertoncello, LJ Bendall, PJ Simmons and DN Haylock. (2005). Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 106:1232-1239.
18. Stier S, Y Ko, R Forkert, C Lutz, T Neuhaus, E Grunewald, T Cheng, D Dombkowski, LM Calvi, SR Rittling and DT Scadden. (2005). Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med 201:1781-1791.
19. Nakayama T, N Mutsuga and G Tosato. (2007). Effect of fibroblast growth factor 2 on stromal cell-derived factor 1 production by bone marrow stromal cells and hematopoiesis. J Natl Cancer Inst 99:223-235.
20. Levesque JP, J Hendy, Y Takamatsu, PJ Simmons and LJ Bendall. (2003). Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J Clin Invest 111:187-196.
21. Pelus LM, D Horowitz, SC Cooper and AG King. (2002). Peripheral blood stem cell mobilization. A role for CXC chemokines. Crit Rev Oncol Hematol 43:257-275.
22. Nakayama T, N Mutsuga and G Tosato. (2007). FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood 109: 1363-1372.
23. Yoon KA, YM Chae and JY Cho. (2009). FGF2 stimulates SDF-1 expression through the Erm transcription factor in Sertoli cells. J Cell Physiol 220:245-256.
24. Murphy PM. (1996). Chemokine receptors: structure, function and role in microbial pathogenesis. Cytokine Growth Factor Rev 7:47-64.
25. Kobayashi Y. (2006). Neutrophil infiltration and chemokines. Crit Rev Immunol 26:307-316.
26. Wright DE, EP Bowman, AJ Wagers, EC Butcher and IL Weissman. (2002). Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med 195:1145-1154.
27. Choong ML, YP Yong, AC Tan, B Luo and HF Lodish. (2004). LIX: a chemokine with a role in hematopoietic stem cells maintenance. Cytokine 25:239-245.
28. Yin T and L Li. (2006). The stem cell niches in bone. J Clin Invest 116:1195-1201.
29. ter Huurne M, CG Figdor and R Torensma. Hematopoietic stem cells are coordinated by the molecular cues of the endosteal niche. Stem Cells Dev 19:1131-1141.
30. Kunisaki Y and PS Frenette. (2012). The secrets of the bone marrow niche: Enigmatic niche brings challenge for HSC expansion. Nat Med 18:864-865.
31. Chitteti BR, YH Cheng, B Poteat, S Rodriguez-Rodriguez, WS Goebel, N Carlesso, MA Kacena and EF Srour. (2010). Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function. Blood 115:3239-3248.
32. Cheng YH, BR Chitteti, DA Streicher, JA Morgan, S Rodriguez-Rodriguez, N Carlesso, EF Srour and MA Kacena. (2011). Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells. J Bone Miner Res 26:1111-1121.
33. Mendez-Ferrer S, TV Michurina, F Ferraro, AR Mazloom, BD Macarthur, SA Lira, DT Scadden, A Ma'ayan, GN Enikolopov and PS Frenette. (2010). Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466:829-834.
34. Nakamura Y, F Arai, H Iwasaki, K Hosokawa, I Kobayashi, Y Gomei, Y Matsumoto, H Yoshihara and T Suda. (2010). Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells. Blood 116: 1422-1432.
35. Ding L, TL Saunders, G Enikolopov and SJ Morrison. (2012). Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 481:457-462.
36. Wang SJ, P Greer and R Auerbach. (1996). Isolation and propagation of yolk-sac-derived endothelial cells from a hypervascular transgenic mouse expressing a gain-offunction fps/fes proto-oncogene. In Vitro Cell Dev Biol Anim 32:292-299.
37. Lu LS, SJ Wang and R Auerbach. (1996). In vitro and in vivo differentiation into B cells, T cells, and myeloid cells of primitive yolk sac hematopoietic precursor cells expanded > 100-fold by coculture with a clonal yolk sac endothelial cell line. Proc Natl Acad Sci U S A 93:14782-14787.
38. O'Connell K, G Landman, E Farmer and M Edidin. (1991). Endothelial cells transformed by SV40 T antigen cause Kaposi's sarcomalike tumors in nude mice. Am J Pathol 139:743-749.
39. O'Connell KA and M Edidin. (1990). A mouse lymphoid endothelial cell line immortalized by simian virus 40 binds lymphocytes and retains functional characteristics of normal endothelial cells. J Immunol 144:521-525.
40. O'Connell KA and AA Rudmann. (1993). Cloned spindle and epithelioid cells from murine Kaposi's sarcoma-like tumors are of endothelial origin. J Invest Dermatol 100:742-745.
41. Bastaki M, EE Nelli, P Dell'Era, M Rusnati, MP Molinari-Tosatti, S Parolini, R Auerbach, LP Ruco, L Possati and M Presta. (1997). Basic fibroblast growth factor-induced angiogenic phenotype in mouse endothelium. A study of aortic and microvascular endothelial cell lines. Arterioscler Thromb Vasc Biol 17:454-464.
42. Salvucci O, L Yao, S Villalba, A Sajewicz, S Pittaluga and G Tosato. (2002). Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1. Blood 99:2703-2711.
43. Ponomaryov T, A Peled, I Petit, RS Taichman, L Habler, J Sandbank, F Arenzana-Seisdedos, A Magerus, A Caruz, et al. (2000). Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function. J Clin Invest 106:1331-1339.
44. Peled A, V Grabovsky, L Habler, J Sandbank, F Arenzana-Seisdedos, I Petit, H Ben-Hur, T Lapidot and R Alon. (1999). The chemokine SDF-1 stimulates integrin-mediated arrest of CD34(+) cells on vascular endothelium under shear flow. J Clin Invest 104:1199-1211.
45. Levesque JP and IG Winkler. (2008). Mobilization of hematopoietic stem cells: state of the art. Curr Opin Organ Transplant 13:53-58.
46. Kortesidis A, A Zannettino, S Isenmann, S Shi, T Lapidot and S Gronthos. (2005). Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood 105:3793-3801.
47. Itkin T, A Ludin, B Gradus, S Gur-Cohen, A Kalinkovich, A Schajnovitz, Y Ovadya, O Kollet, J Canaani, et al. (2012). FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation and CXCL12 downregulation. Blood. [Epub ahead of print]; DOI: 10.1182/blood-2011-11-394692.
48. Tzeng YS, H Li, YL Kang, WC Chen, WC Cheng and DM Lai. Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression. Blood 117:429-439.
49. Kim KA, M Wagle, K Tran, X Zhan, MA Dixon, S Liu, D Gros,WKorver, S Yonkovich, et al. (2008). R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol Biol Cell 19:2588-2596.
50. Yamada W, K Nagao, K Horikoshi, A Fujikura, E Ikeda, Y Inagaki, M Kakitani, K Tomizuka, H Miyazaki, T Suda and K Takubo. (2009). Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun 381: 453-458.
51. Kazanskaya O, B Ohkawara, M Heroult, W Wu, N Maltry, HG Augustin and C Niehrs. (2008). The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development 135:3655-3664.
52. Mei J, Y Liu, N Dai, M Favara, T Greene, S Jeyaseelan, M Poncz, JS Lee and GS Worthen. CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection. Immunity 33:106-117.
53. Eash KJ, AM Greenbaum, PK Gopalan and DC Link. (2010). CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. J Clin Invest 120: 2423-2431.
54. Tefferi A. (2000). Myelofibrosis with myeloid metaplasia. N Engl J Med 342:1255-1265.
55. Thiele J, C Braeckel, S Wagner, B Falini, D Dienemann, H Stein and R Fischer. (1992). Macrophages in normal human bone marrow and in chronic myeloproliferative disorders: an immunohistochemical and morphometric study by a new monoclonal antibody (PG-M1) on trephine biopsies. Virchows Arch A Pathol Anat Histopathol 421:33-39.
56. Mesa RA, CA Hanson, SV Rajkumar, G Schroeder and A Tefferi. (2000). Evaluation and clinical correlations of bone marrow angiogenesis in myelofibrosis with myeloid metaplasia. Blood 96:3374-3380.
57. Gupta RR, DJ Yoo, C Hebert, C Niger and JP Stains. (2010). Induction of an osteocyte-like phenotype by fibroblast growth factor-2. Biochem Biophys Res Commun 402: 258-264.
58. Xiao L, P Liu, X Li, T Doetschman, JD Coffin, H Drissi and MM Hurley. (2009). Exported 18-kDa isoform of fibroblast growth factor-2 is a critical determinant of bone mass in mice. J Biol Chem 284:3170-3182.
59. Montero A, Y Okada, M Tomita, M Ito, H Tsurukami, T Nakamura, T Doetschman, JD Coffin and MM Hurley. (2000). Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation. J Clin Invest 105:1085-1093.
60. Eswarakumar VP, I Lax and J Schlessinger. (2005). Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev 16:139-149.
61. Zhang X, OA Ibrahimi, SK Olsen, H Umemori, M Mohammadi and DM Ornitz. (2006). Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 281:15694-15700.
62. Ornitz DM, J Xu, JS Colvin, DG McEwen, CA MacArthur, F Coulier, G Gao and M Goldfarb. (1996). Receptor specificity of the fibroblast growth factor family. J Biol Chem 271: 15292-15297.