Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway

Journal of Cellular Biochemistry

Volumn 115, Issue 6, 2014, Pages 1166-1175

  Shao, Shiying ^a   Nie, Mingbo ^a   Chen, Cai ^a   Chen, Xi ^a   Zhang, Muxun ^a   Yuan, Gang ^a   Yu, Xuefeng ^a   Yang, Yan ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

BETA CELL FUNCTION; FORKHEAD TRANSCRIPTION FACTOR CLASS O; GLUCAGON LIKE PEPTIDE 1; LIPOTOXICITY; TYPE 2 DIABETES MELLITUS

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYTOPLASM PROTEIN; FATTY ACID; INSULIN; LIRAGLUTIDE; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN KINASE B; PROTEIN P27; TRANSCRIPTION FACTOR FKHR; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; APOPTOSIS REGULATORY PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CHROMONE DERIVATIVE; CIDEA PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; GLUCAGON LIKE PEPTIDE 1; HOMEODOMAIN PROTEIN; MAFA PROTEIN, MOUSE; MORPHOLINE DERIVATIVE; NERVE PROTEIN; NEUROGENIC DIFFERENTIATION FACTOR; PANCREATIC AND DUODENAL HOMEOBOX 1 PROTEIN; PROTECTIVE AGENT; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR MAF;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL FUNCTION; CELL PROLIFERATION; CELL PROTECTION; CELL STRESS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; INSULIN RELEASE; INSULINOMA; LIPOTOXICITY; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION (PROCESS); TOXICITY; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMONES; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FATTY ACIDS, NONESTERIFIED; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; GLUCAGON-LIKE PEPTIDE 1; HOMEODOMAIN PROTEINS; INSULIN; INSULIN-SECRETING CELLS; MAF TRANSCRIPTION FACTORS, LARGE; MICE, INBRED C57BL; MORPHOLINES; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 84907422947     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24763     Document Type: Article

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