메뉴 건너뛰기




Volumn 9, Issue 9, 2014, Pages

Podocyte injury caused by indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ 4; AROMATIC HYDROCARBON RECEPTOR; BETA3 INTEGRIN; BETA4 INTEGRIN; BETA5 INTEGRIN; BETA6 INTEGRIN; CD18 ANTIGEN; CD2 ASSOCIATED PROTEIN; CYTOCHROME P450 1A1; INDICAN; MESSENGER RNA; NEPHRIN; PODOCIN; PROTEIN CDC42; RAC1 PROTEIN; SYNAPTOPODIN; VIMENTIN; WT1 PROTEIN; LIGAND;

EID: 84907215528     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108448     Document Type: Article
Times cited : (86)

References (62)
  • 2
    • 73349083067 scopus 로고    scopus 로고
    • Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients
    • Barreto FC, Barreto DV, Liabeuf S, Meert N, Glorieux G, et al. (2009) Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients. Clin J Am Soc Nephrol 4: 1551-1558
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 1551-1558
    • Barreto, F.C.1    Barreto, D.V.2    Liabeuf, S.3    Meert, N.4    Glorieux, G.5
  • 3
    • 79251528072 scopus 로고    scopus 로고
    • Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress
    • Yu M, Kim YJ, Kang DH (2011) Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress. Clin J Am Soc Nephrol 6: 30-39
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 30-39
    • Yu, M.1    Kim, Y.J.2    Kang, D.H.3
  • 5
    • 79952098353 scopus 로고    scopus 로고
    • Genomic damage in endstage renal disease-contribution of uremic toxins
    • Schupp N, Heidland A, Stopper H (2010) Genomic damage in endstage renal disease-contribution of uremic toxins. Toxins 2: 2340-2358
    • (2010) Toxins , vol.2 , pp. 2340-2358
    • Schupp, N.1    Heidland, A.2    Stopper, H.3
  • 6
    • 78650684104 scopus 로고    scopus 로고
    • Indoxyl sulfate reduces klotho expression and promotes senescence in the kidneys of hypertensive rats
    • Adijiang A, Shimizu H, Higuchi Y, Nishijima F, Niwa T (2011) Indoxyl sulfate reduces klotho expression and promotes senescence in the kidneys of hypertensive rats. J Ren Nutr 21: 105-109
    • (2011) J Ren Nutr , vol.21 , pp. 105-109
    • Adijiang, A.1    Shimizu, H.2    Higuchi, Y.3    Nishijima, F.4    Niwa, T.5
  • 7
    • 84855179279 scopus 로고    scopus 로고
    • Indoxyl sulfate induces endothelial cell senescence by increasing reactive oxygen species production and p53 activity
    • Adelibieke Y, Shimizu H, Muteliefu G, Bolati D, Niwa T (2012) Indoxyl sulfate induces endothelial cell senescence by increasing reactive oxygen species production and p53 activity. J Ren Nutr 22: 86-89
    • (2012) J Ren Nutr , vol.22 , pp. 86-89
    • Adelibieke, Y.1    Shimizu, H.2    Muteliefu, G.3    Bolati, D.4    Niwa, T.5
  • 8
    • 33744809267 scopus 로고    scopus 로고
    • Indoxyl sulfate induces complex redox alterations in mesangial cells
    • Gelasco AK, Raymond JR, Andrew K (2006) Indoxyl sulfate induces complex redox alterations in mesangial cells. Am J Physiol Renal Physiol 290: 1551-1558
    • (2006) Am J Physiol Renal Physiol , vol.290 , pp. 1551-1558
    • Gelasco, A.K.1    Raymond, J.R.2    Andrew, K.3
  • 9
    • 79953055289 scopus 로고    scopus 로고
    • New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant
    • Miyamoto Y,Watanabe H, Otagiri M, Maruyama T (2011) New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant. Ther Apher Dial 15: 129-131
    • (2011) Ther Apher Dial , vol.15 , pp. 129-131
    • Miyamoto, Y.1    Watanabe, H.2    Otagiri, M.3    Maruyama, T.4
  • 10
    • 77950605070 scopus 로고    scopus 로고
    • Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NFkappaB activation
    • Tumur Z, Shimizu H, Enomoto A, Miyazaki H, Niwa T (2010) Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NFkappaB activation. Am J Nephrol 31: 435-441
    • (2010) Am J Nephrol , vol.31 , pp. 435-441
    • Tumur, Z.1    Shimizu, H.2    Enomoto, A.3    Miyazaki, H.4    Niwa, T.5
  • 11
    • 0027935771 scopus 로고
    • Progression of glomerular sclerosis in experimental uremic rats by administration of indole, a precursor of indoxyl sulfate
    • Niwa T, Ise M, Miyazaki T (1994) Progression of glomerular sclerosis in experimental uremic rats by administration of indole, a precursor of indoxyl sulfate. Am J Nephrol 14: 207-212
    • (1994) Am J Nephrol , vol.14 , pp. 207-212
    • Niwa, T.1    Ise, M.2    Miyazaki, T.3
  • 12
    • 0035996187 scopus 로고    scopus 로고
    • Effects of oral adsorbent AST-120 (Kremezin) on renal function and glomerular injury in early-stage renal failure of subtotal nephrectomized rats
    • Kobayashi N, Maeda A, Horikoshi S, Shirato I, Tomino Y, et al. (2002) Effects of oral adsorbent AST-120 (Kremezin) on renal function and glomerular injury in early-stage renal failure of subtotal nephrectomized rats. Nephron 91: 480-485
    • (2002) Nephron , vol.91 , pp. 480-485
    • Kobayashi, N.1    Maeda, A.2    Horikoshi, S.3    Shirato, I.4    Tomino, Y.5
  • 13
    • 0037406406 scopus 로고    scopus 로고
    • Review on uremic toxins: Classification, concentration, and interindividual variability
    • Vanholder R, De Smet R, Glorieux G, Argilés A, Baurmeister U, et al. (2003) Review on uremic toxins: classification, concentration, and interindividual variability. Kidney Int 63: 1934-1943
    • (2003) Kidney Int , vol.63 , pp. 1934-1943
    • Vanholder, R.1    De Smet, R.2    Glorieux, G.3    Argilés, A.4    Baurmeister, U.5
  • 14
    • 0035149859 scopus 로고    scopus 로고
    • An oral adsorbent ameliorates renal overload of indoxyl sulfate and progression of renal failure in diabetic rats
    • Aoyama I, Niwa T (2001) An oral adsorbent ameliorates renal overload of indoxyl sulfate and progression of renal failure in diabetic rats. Am J Kidney Dis 37: S7-S12
    • (2001) Am J Kidney Dis , vol.37 , pp. S7-S12
    • Aoyama, I.1    Niwa, T.2
  • 15
    • 18444385667 scopus 로고    scopus 로고
    • Role of Organic Anion Transporters in the Tubular Transport of Indoxyl Sulfate and the Induction of its Nephrotoxicity
    • Enomoto A, Takeda M, Tojo A, Sekine T, Cha SH (2002) Role of Organic Anion Transporters in the Tubular Transport of Indoxyl Sulfate and the Induction of its Nephrotoxicity. J Am Soc Nephrol 13: 1711-1720
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1711-1720
    • Enomoto, A.1    Takeda, M.2    Tojo, A.3    Sekine, T.4    Cha, S.H.5
  • 16
    • 75349102699 scopus 로고    scopus 로고
    • The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor
    • Schroeder JC, Dinatale BC, Murray IA, Flaveny CA, Liu Q, et al. (2010) The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor. Biochemistry 49: 393-400
    • (2010) Biochemistry , vol.49 , pp. 393-400
    • Schroeder, J.C.1    Dinatale, B.C.2    Murray, I.A.3    Flaveny, C.A.4    Liu, Q.5
  • 18
    • 72949115099 scopus 로고    scopus 로고
    • The mammalian aryl hydrocarbon (Ah) receptor: From mediator of dioxin toxicity toward physiological functions in skin and liver
    • Bock KW, Köhle C (2009) The mammalian aryl hydrocarbon (Ah) receptor: from mediator of dioxin toxicity toward physiological functions in skin and liver. Biol Chem 390: 1225-1235
    • (2009) Biol Chem , vol.390 , pp. 1225-1235
    • Bock, K.W.1    Köhle, C.2
  • 19
    • 50849112720 scopus 로고    scopus 로고
    • Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin
    • Nishimura N, Matsumura F, Vogel CF, Nishimura H, Yonemoto J, et al. (2008) Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin. Toxicol Appl Pharmacol 231: 374-383
    • (2008) Toxicol Appl Pharmacol , vol.231 , pp. 374-383
    • Nishimura, N.1    Matsumura, F.2    Vogel, C.F.3    Nishimura, H.4    Yonemoto, J.5
  • 21
    • 82855172225 scopus 로고    scopus 로고
    • AHR regulates WT1 genetic programming during murine nephrogenesis
    • Falahatpisheh MH, Nanez A, Ramos KS (2011) AHR regulates WT1 genetic programming during murine nephrogenesis. Mol Med 17: 1275-1284
    • (2011) Mol Med , vol.17 , pp. 1275-1284
    • Falahatpisheh, M.H.1    Nanez, A.2    Ramos, K.S.3
  • 22
    • 0033049368 scopus 로고    scopus 로고
    • Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization
    • Dey A, Jones JE, Nebert DW (1999) Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization. Biochem Pharmacol 58: 525-537
    • (1999) Biochem Pharmacol , vol.58 , pp. 525-537
    • Dey, A.1    Jones, J.E.2    Nebert, D.W.3
  • 23
    • 0023608290 scopus 로고
    • Immunohistochemical Determination of Inducibility Phenotype with a Monoclonal Antibody to a Methylcholanthrene-inducible Isozyme of Cytochrome P- 450
    • Anderson LM, Ward JM, Park SS, Jones AB, Junker JL, et al. (1987) Immunohistochemical Determination of Inducibility Phenotype with a Monoclonal Antibody to a Methylcholanthrene-inducible Isozyme of Cytochrome P- 450. Cancer Res 47: 6079-6085
    • (1987) Cancer Res , vol.47 , pp. 6079-6085
    • Anderson, L.M.1    Ward, J.M.2    Park, S.S.3    Jones, A.B.4    Junker, J.L.5
  • 24
    • 84865707513 scopus 로고    scopus 로고
    • Role of the podocyte (and glomerular endothelium) in building the GBM
    • Abrahamson DR (2012) Role of the podocyte (and glomerular endothelium) in building the GBM. Semin Nephrol 32: 342-349
    • (2012) Semin Nephrol , vol.32 , pp. 342-349
    • Abrahamson, D.R.1
  • 25
    • 84857243208 scopus 로고    scopus 로고
    • Cell biology and pathology of podocytes
    • Greka A, Mundel P (2012) Cell biology and pathology of podocytes. Annu Rev Physiol 74: 299-323
    • (2012) Annu Rev Physiol , vol.74 , pp. 299-323
    • Greka, A.1    Mundel, P.2
  • 26
    • 70349330816 scopus 로고    scopus 로고
    • New insights into the role of podocytes in proteinuria
    • Patrakka J, Tryggvason K (2009) New insights into the role of podocytes in proteinuria. Nat Rev Nephrol 5: 463-468
    • (2009) Nat Rev Nephrol , vol.5 , pp. 463-468
    • Patrakka, J.1    Tryggvason, K.2
  • 27
    • 66449090788 scopus 로고    scopus 로고
    • Susceptibility loci for murine HIV-associated nephropathy encode transregulators of podocyte gene expression
    • Papeta N, Chan KT, Prakash S, Martino J, Kiryluk K, et al. (2009) Susceptibility loci for murine HIV-associated nephropathy encode transregulators of podocyte gene expression. J Clin Invest 119: 1178-1188
    • (2009) J Clin Invest , vol.119 , pp. 1178-1188
    • Papeta, N.1    Chan, K.T.2    Prakash, S.3    Martino, J.4    Kiryluk, K.5
  • 28
    • 33749240181 scopus 로고    scopus 로고
    • HIV-1 genes vpr and nef synergistically damage podocytes, leading to glomerulosclerosis
    • Zuo Y, Matsusaka T, Zhong J, Ma J, Ma LJ, et al. (2006) HIV-1 genes vpr and nef synergistically damage podocytes, leading to glomerulosclerosis. J Am Soc Nephrol 17: 2832-2843
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2832-2843
    • Zuo, Y.1    Matsusaka, T.2    Zhong, J.3    Ma, J.4    Ma, L.J.5
  • 30
    • 65449147992 scopus 로고    scopus 로고
    • Sodium octanoate to reverse indoxyl sulfate and p-cresyl sulfate albumin binding in uremic and normal serum during sample preparation followed by fluorescence liquid chromatography
    • de Loor H, Meijers BK, Meyer TW, Bammens B, Verbeke K, et al. (2009) Sodium octanoate to reverse indoxyl sulfate and p-cresyl sulfate albumin binding in uremic and normal serum during sample preparation followed by fluorescence liquid chromatography. J Chromatogr A 1216: 4684-4688
    • (2009) J Chromatogr A , vol.1216 , pp. 4684-4688
    • De Loor, H.1    Meijers, B.K.2    Meyer, T.W.3    Bammens, B.4    Verbeke, K.5
  • 31
    • 50049083279 scopus 로고    scopus 로고
    • Tetracycline-inducible gene expression in conditionally immortalized mouse podocytes
    • Kajiyama H, Titus S, Austin CP, Chiotos K, Matsumoto T, et al. (2009) Tetracycline-inducible gene expression in conditionally immortalized mouse podocytes. Am J Nephrol 29: 153-163
    • (2009) Am J Nephrol , vol.29 , pp. 153-163
    • Kajiyama, H.1    Titus, S.2    Austin, C.P.3    Chiotos, K.4    Matsumoto, T.5
  • 32
    • 0036189998 scopus 로고    scopus 로고
    • A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression
    • Saleem M, O'Hare MJ, Reiser J, Coward RJ, Inward CD, et al. (2002) A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol 13: 630-638
    • (2002) J Am Soc Nephrol , vol.13 , pp. 630-638
    • Saleem, M.1    O'hare, M.J.2    Reiser, J.3    Coward, R.J.4    Inward, C.D.5
  • 33
    • 67650357563 scopus 로고    scopus 로고
    • Development of a biomarker assay for 3- indoxyl sulfate in mouse plasma and brain by liquid chromatography/tandem mass spectrometry
    • Wang G, Korfmacher WA (2009) Development of a biomarker assay for 3- indoxyl sulfate in mouse plasma and brain by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 23: 2061-2069
    • (2009) Rapid Commun Mass Spectrom , vol.23 , pp. 2061-2069
    • Wang, G.1    Korfmacher, W.A.2
  • 34
    • 72749094547 scopus 로고    scopus 로고
    • Serine-71 phosphorylation of Rac1/Cdc42 diminishes the pathogenic effect of Clostridium difficile toxin A
    • Schoentaube J, Olling A, Tatge H, Just I, Gerhard R (2009) Serine-71 phosphorylation of Rac1/Cdc42 diminishes the pathogenic effect of Clostridium difficile toxin A. Cell Microbiol 11: 1816-1826
    • (2009) Cell Microbiol , vol.11 , pp. 1816-1826
    • Schoentaube, J.1    Olling, A.2    Tatge, H.3    Just, I.4    Gerhard, R.5
  • 35
    • 84874934810 scopus 로고    scopus 로고
    • LPS and PAN-induced podocyte injury in an in vitro model of minimal change disease: Changes in TLR profile
    • Srivastava T, Sharma M, Yew K-H, Sharma R, Duncan RS, et al. (2013) LPS and PAN-induced podocyte injury in an in vitro model of minimal change disease: changes in TLR profile. J Cell Commun Signal 7: 49-60
    • (2013) J Cell Commun Signal , vol.7 , pp. 49-60
    • Srivastava, T.1    Sharma, M.2    Yew, K.-H.3    Sharma, R.4    Duncan, R.S.5
  • 36
    • 0025730125 scopus 로고
    • Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells
    • Zoja C, Wang JM, Bettoni S, Sironi M, Renzi D, et al. (1991) Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells. Am J Pathol 138: 991-1003
    • (1991) Am J Pathol , vol.138 , pp. 991-1003
    • Zoja, C.1    Wang, J.M.2    Bettoni, S.3    Sironi, M.4    Renzi, D.5
  • 37
    • 0034094660 scopus 로고    scopus 로고
    • Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1b, IL-6, IL-8, IL-10 and TNF-A from normal human mononuclear cells involving in the lupus pathogenesis
    • Sun KH, Yu CL, Tang SJ, Sun GH (2000) Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1b, IL-6, IL-8, IL-10 and TNF-a from normal human mononuclear cells involving in the lupus pathogenesis. Immunology 2000; 99: 352-360
    • (2000) Immunology , vol.2000 , Issue.99 , pp. 352-360
    • Sun, K.H.1    Yu, C.L.2    Tang, S.J.3    Sun, G.H.4
  • 38
    • 23944525929 scopus 로고    scopus 로고
    • Molecular pathomechanisms of membranous nephropathy: From Heymann nephritis to alloimmunization
    • Ronco P, Debiec H (2005) Molecular pathomechanisms of membranous nephropathy: from Heymann nephritis to alloimmunization. J Am Soc Nephrol 16: 1205-1213
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1205-1213
    • Ronco, P.1    Debiec, H.2
  • 39
    • 0028982596 scopus 로고
    • Beta 1 and beta 3 integrin upregulation in rapidly progressive glomerulonephritis
    • Baraldi A, Zambruno G, Furci L, Ballestri M, Tombesi A, et al. (1995) Beta 1 and beta 3 integrin upregulation in rapidly progressive glomerulonephritis. Nephrol Dial Transplant 10: 1155-1161
    • (1995) Nephrol Dial Transplant , vol.10 , pp. 1155-1161
    • Baraldi, A.1    Zambruno, G.2    Furci, L.3    Ballestri, M.4    Tombesi, A.5
  • 40
    • 37849026460 scopus 로고    scopus 로고
    • Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus
    • Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, et al. (2008) Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev Biol 313: 584-593
    • (2008) Dev Biol , vol.313 , pp. 584-593
    • Kanasaki, K.1    Kanda, Y.2    Palmsten, K.3    Tanjore, H.4    Lee, S.B.5
  • 42
    • 77955878413 scopus 로고    scopus 로고
    • Expression of aryl hydrocarbon receptor in human placentas and fetal tissues
    • Jiang Y, Wang K, Fang R, Zheng J (2010) Expression of aryl hydrocarbon receptor in human placentas and fetal tissues. J Histochem Cytochem 58: 679-685
    • (2010) J Histochem Cytochem , vol.58 , pp. 679-685
    • Jiang, Y.1    Wang, K.2    Fang, R.3    Zheng, J.4
  • 43
    • 0033762864 scopus 로고    scopus 로고
    • An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-b1 in uraemic rat kidneys
    • Miyazaki T, Aoyama I, Ise M, Seo H, Niwa T (2000) An oral sorbent reduces overload of indoxyl sulphate and gene expression of TGF-b1 in uraemic rat kidneys. Nephrol Dial Transplant 2000; 15: 1773-1781
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 1773-1781
    • Miyazaki, T.1    Aoyama, I.2    Ise, M.3    Seo, H.4    Niwa, T.5
  • 44
    • 84859144273 scopus 로고    scopus 로고
    • Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelialto- mesenchymal transition
    • Sun CY, Chang SC, Wu MS (2012) Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelialto- mesenchymal transition. PLoS One 7: e34026
    • (2012) PLoS One , vol.7 , pp. e34026
    • Sun, C.Y.1    Chang, S.C.2    Wu, M.S.3
  • 45
    • 84859111301 scopus 로고    scopus 로고
    • Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-kB, p53, ERK, and JNK in proximal tubular cells
    • Shimizu H, Bolati D, Higashiyama Y, Nishijima F, Shimizu K, et al. (2012) Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-kB, p53, ERK, and JNK in proximal tubular cells. Life Sci 90: 525-530
    • (2012) Life Sci , vol.90 , pp. 525-530
    • Shimizu, H.1    Bolati, D.2    Higashiyama, Y.3    Nishijima, F.4    Shimizu, K.5
  • 46
    • 79952346794 scopus 로고    scopus 로고
    • Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-kB
    • Shimizu H, Bolati D, Adijiang A, Adelibieke Y, Muteliefu G, et al. (2011) Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-kB. Am J Nephrol 33: 319-324
    • (2011) Am J Nephrol , vol.33 , pp. 319-324
    • Shimizu, H.1    Bolati, D.2    Adijiang, A.3    Adelibieke, Y.4    Muteliefu, G.5
  • 47
    • 33748905886 scopus 로고    scopus 로고
    • Intrarenal oxygenation in chronic renal failure
    • Norman JT, Fine LG (2006) Intrarenal oxygenation in chronic renal failure. Clin Exp Pharmacol Physiol 33: 989-996
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 989-996
    • Norman, J.T.1    Fine, L.G.2
  • 48
    • 84855173798 scopus 로고    scopus 로고
    • Indoxyl sulfate induces nephrovascular senescence
    • Niwa T, Shimizu H (2012) Indoxyl sulfate induces nephrovascular senescence. J Ren Nutr 22: 102-106
    • (2012) J Ren Nutr , vol.22 , pp. 102-106
    • Niwa, T.1    Shimizu, H.2
  • 49
    • 84859321859 scopus 로고    scopus 로고
    • Indoxyl sulfate-induced epithelial-to-mesenchymal transition and apoptosis of renal tubular cells as novel mechanisms of progression of renal disease
    • Kim SH, Yu MA, Ryu ES, Jang YH, Kang DH (2012) Indoxyl sulfate-induced epithelial-to-mesenchymal transition and apoptosis of renal tubular cells as novel mechanisms of progression of renal disease. Lab Invest 92: 488-498
    • (2012) Lab Invest , vol.92 , pp. 488-498
    • Kim, S.H.1    Yu, M.A.2    Ryu, E.S.3    Jang, Y.H.4    Kang, D.H.5
  • 50
    • 84863288392 scopus 로고    scopus 로고
    • Effects of indoxyl sulfate on adherens junctions of endothelial cells and the underlying signaling mechanism
    • Peng YS, Lin YT, Chen Y, Hung KY, Wang SM (2012) Effects of indoxyl sulfate on adherens junctions of endothelial cells and the underlying signaling mechanism. J Cell Biochem 113: 1034-1043
    • (2012) J Cell Biochem , vol.113 , pp. 1034-1043
    • Peng, Y.S.1    Lin, Y.T.2    Chen, Y.3    Hung, K.Y.4    Wang, S.M.5
  • 51
    • 0028831889 scopus 로고
    • Podocytes loose their adhesive phenotype in focal segmental glomerulosclerosis
    • Kemeny E, Mihatsch MJ, Dürmüller U, Gudat F (1995) Podocytes loose their adhesive phenotype in focal segmental glomerulosclerosis. Clin Nephrol 43: 71-83
    • (1995) Clin Nephrol , vol.43 , pp. 71-83
    • Kemeny, E.1    Mihatsch, M.J.2    Dürmüller, U.3    Gudat, F.4
  • 52
    • 33645577952 scopus 로고    scopus 로고
    • Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury
    • Zou J, Yaoita E, Watanabe Y, Yoshida Y, Nameta M, et al. (2006) Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Virchows Arch 448: 485-492
    • (2006) Virchows Arch , vol.448 , pp. 485-492
    • Zou, J.1    Yaoita, E.2    Watanabe, Y.3    Yoshida, Y.4    Nameta, M.5
  • 53
    • 79551651126 scopus 로고    scopus 로고
    • Quantitative and qualitative urinary cellular patterns correlate with progression of murine glomerulonephritis
    • Kimura J, Ichii O, Otsuka S, Kanazawa T, Namiki Y, et al. (2011) Quantitative and qualitative urinary cellular patterns correlate with progression of murine glomerulonephritis. PLoS One 6: e16472
    • (2011) PLoS One , vol.6 , pp. e16472
    • Kimura, J.1    Ichii, O.2    Otsuka, S.3    Kanazawa, T.4    Namiki, Y.5
  • 54
    • 70349308229 scopus 로고    scopus 로고
    • Aryl-hydrocarbon receptor-dependent alteration of FAK/RhoA in the inhibition of HUVEC motility by 3-methylcholanthrene
    • Chang CC, Tsai SY, Lin H, Li HF, Lee YH, et al. (2009) Aryl-hydrocarbon receptor-dependent alteration of FAK/RhoA in the inhibition of HUVEC motility by 3-methylcholanthrene. Cell Mol Life Sci 66: 3193-3205
    • (2009) Cell Mol Life Sci , vol.66 , pp. 3193-3205
    • Chang, C.C.1    Tsai, S.Y.2    Lin, H.3    Li, H.F.4    Lee, Y.H.5
  • 57
    • 33947393625 scopus 로고    scopus 로고
    • Rhofamily small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro
    • Gao SY, Li CY, Shimokawa T, Terashita T, Matsuda S, et al. (2007). Rhofamily small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro. Cell Tissue Res 328: 391-400
    • (2007) Cell Tissue Res , vol.328 , pp. 391-400
    • Gao, S.Y.1    Li, C.Y.2    Shimokawa, T.3    Terashita, T.4    Matsuda, S.5
  • 58
    • 84865788310 scopus 로고    scopus 로고
    • Signaling from the podocyte intercellular junction to the actin cytoskeleton
    • George B, Holzman LB (2012) Signaling from the podocyte intercellular junction to the actin cytoskeleton. Semin Nephrol 32: 307-318
    • (2012) Semin Nephrol , vol.32 , pp. 307-318
    • George, B.1    Holzman, L.B.2
  • 59
    • 84897493761 scopus 로고    scopus 로고
    • Indoxyl sulfate downregulates expression of mas receptor via OAT3/AhR/Stat3 pathway in proximal tubular cells
    • Ng HY, Yisireyili M, Saito S, Lee CT, Adelibieke Y, et al. (2014) Indoxyl Sulfate Downregulates Expression of Mas Receptor via OAT3/AhR/Stat3 Pathway in Proximal Tubular Cells. PLoS One 9: e91517
    • (2014) PLoS One , vol.9 , pp. e91517
    • Ng, H.Y.1    Yisireyili, M.2    Saito, S.3    Lee, C.T.4    Adelibieke, Y.5
  • 60
    • 84868552956 scopus 로고    scopus 로고
    • Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration
    • Mutsaers HA, Wilmer MJ, Reijnders D, Jansen J, van den Broek PH, et al. (2013) Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration. Biochim Biophys Acta 1832: 142-150
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 142-150
    • Mutsaers, H.A.1    Wilmer, M.J.2    Reijnders, D.3    Jansen, J.4    Van Den Broek, P.H.5
  • 61
    • 59149104324 scopus 로고    scopus 로고
    • A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family
    • Vogel CF, Matsumura F (2009) A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kappaB family. Biochem Pharmacol 77: 734-745
    • (2009) Biochem Pharmacol , vol.77 , pp. 734-745
    • Vogel, C.F.1    Matsumura, F.2
  • 62
    • 42649095378 scopus 로고    scopus 로고
    • Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
    • Quintana FJ, Basso AS, Iglesias AH, Korn T, Farez MF, et al. (2008) Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature 453: 65-71.
    • (2008) Nature , vol.453 , pp. 65-71
    • Quintana, F.J.1    Basso, A.S.2    Iglesias, A.H.3    Korn, T.4    Farez, M.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.