-
1
-
-
0019304713
-
Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion
-
Kanwar, Y. S., Linker, A. & Farquhar, M. G. Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion. J. Cell Biol. 86, 688-693 (1980).
-
(1980)
J. Cell Biol.
, vol.86
, pp. 688-693
-
-
Kanwar, Y.S.1
Linker, A.2
Farquhar, M.G.3
-
2
-
-
0037439268
-
Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney
-
Rossi, M. et al. Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney. EMBO J. 22, 236-245 (2003)
-
(2003)
EMBO J.
, vol.22
, pp. 236-245
-
-
Rossi, M.1
-
3
-
-
34547680445
-
Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity
-
Harvey, S. J. et al. Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity. Am. J. Pathol. 171, 139-152 (2007).
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 139-152
-
-
Harvey, S.J.1
-
4
-
-
67651089928
-
Glomerular filtration is normal in the absence of both agrin and perlecan-heparan sulfate from the glomerular basement membrane
-
doi:10.1093/ndt/gfn758
-
Goldberg, s., Harvey, s. J., Cunningham, J., Tryggvason, K. & Miner, J. H. Glomerular filtration is normal in the absence of both agrin and perlecan-heparan sulfate from the glomerular basement membrane. Nephrol. Dial. Transplant. doi:10.1093/ndt/gfn758.
-
Nephrol. Dial. Transplant
-
-
Goldberg, S.1
Harvey, S.J.2
Cunningham, J.3
Tryggvason, K.4
Miner, J.H.5
-
5
-
-
33645403170
-
Hereditary proteinuria syndromes and mechanisms of proteinuria
-
Tryggvason, K., Patrakka, J. & Wartiovaara, J. Hereditary proteinuria syndromes and mechanisms of proteinuria. N. Engl. J. Med. 354, 1387-1401 (2006).
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1387-1401
-
-
Tryggvason, K.1
Patrakka, J.2
Wartiovaara, J.3
-
6
-
-
42149122041
-
Properties of the glomerular barrier and mechanisms of proteinuria
-
Haraldsson, B., Nystrom, J. & Deen, W. M. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol. Rev. 88, 451-487 (2008).
-
(2008)
Physiol. Rev.
, Issue.88
, pp. 451-487
-
-
Haraldsson, B.1
Nystrom, J.2
Deen, W.M.3
-
7
-
-
58149504280
-
Adriamycin alters glomerular endothelium to induce proteinuria
-
Jeansson, M., Bjorck, K., Tenstad, O. & Haraldsson, B. Adriamycin alters glomerular endothelium to induce proteinuria. J. Am. Soc. Nephrol. 20, 114-122 (2009).
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 114-122
-
-
Jeansson, M.1
Bjorck, K.2
Tenstad, O.3
Haraldsson, B.4
-
8
-
-
33644806727
-
Morphological and functional evidence for an important role of the endothelial cell glycocalyx in the glomerular barrier
-
Jeansson, M. & Haraldsson, B. Morphological and functional evidence for an important role of the endothelial cell glycocalyx in the glomerular barrier. Am. J. Physiol. Renal Physiol. 290, F111-F116 (2006)
-
(2006)
Am. J. Physiol. Renal Physiol.
, vol.290
-
-
Jeansson, M.1
Haraldsson, B.2
-
9
-
-
40849130173
-
VeGF inhibition and renal thrombotic microangiopathy
-
Eremina, V. et al. veGF inhibition and renal thrombotic microangiopathy. N. Engl. J. Med. 358, 1129-1136 (2008)
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1129-1136
-
-
Eremina, V.1
-
10
-
-
0037370325
-
Glomerular-specific alterations of veGF-A expression lead to distinct congenital and acquired renal diseases
-
eremina, v. et al. Glomerular-specific alterations of veGF-A expression lead to distinct congenital and acquired renal diseases. J. Clin. Invest. 111, 707-716 (2003).
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 707-716
-
-
Eremina, V.1
-
11
-
-
0038469583
-
Alport's syndrome, Goodpasture's syndrome, and type iv collagen
-
Hudson, B. G., Tryggvason, K., Sundaramoorthy, M. & Neilson, E. G. Alport's syndrome, Goodpasture's syndrome, and type iv collagen. N. Engl. J. Med. 348, 2543-2556 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 2543-2556
-
-
Hudson, B.G.1
Tryggvason, K.2
Sundaramoorthy, M.3
Neilson, E.G.4
-
12
-
-
5744238949
-
Structurally altered basement membranes and hydrocephalus in a type Xviii collagen deficient mouse line
-
Utriainen, A. et al. structurally altered basement membranes and hydrocephalus in a type Xviii collagen deficient mouse line. Hum. Mol. Genet. 13, 2089-2099 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2089-2099
-
-
Utriainen, A.1
-
13
-
-
24344440893
-
Building the glomerulus: A matricentric view
-
Miner, J. H. Building the glomerulus: a matricentric view. J. Am. Soc. Nephrol. 16, 857-861 (2005).
-
(2005)
J. Am. Soc. Nephrol.
, vol.16
, pp. 857-861
-
-
Miner, J.H.1
-
14
-
-
0029127384
-
The renal glomerulus of mice lacking s-laminin/laminin β2: Nephrosis despite molecular compensation by laminin β1
-
Noakes, P. G. et al. The renal glomerulus of mice lacking s-laminin/laminin β2: nephrosis despite molecular compensation by laminin β1. Nat. Genet. 10, 400-406 (1995).
-
(1995)
Nat. Genet.
, vol.10
, pp. 400-406
-
-
Noakes, P.G.1
-
15
-
-
8444221929
-
Human laminin β2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities
-
DOI 10.1093/hmg/ddh284
-
Zenker, M. et al. Human laminin β2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities. Hum. Mol. Genet. 13, 2625-2632 (2004). (Pubitemid 39485411)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.21
, pp. 2625-2632
-
-
Zenker, M.1
Aigner, T.2
Wendler, O.3
Tralau, T.4
Muntefering, H.5
Fenski, R.6
Pitz, S.7
Schumacher, V.8
Royer-Pokora, B.9
Wuhl, E.10
Cochat, P.11
Bouvier, R.12
Kraus, C.13
Mark, K.14
Madlon, H.15
Dotsch, J.16
Rascher, W.17
Maruniak-Chudek, I.18
Lennert, T.19
Neumann, L.M.20
Reis, A.21
more..
-
16
-
-
33746730496
-
-/- mice, implicating the glomerular basement membrane as an albumin barrier
-
Jarad, G., Cunningham, J., shaw, A. s. & Miner, J. H. Proteinuria precedes podocyte abnormalities inLamb2-/-mice, implicating the glomerular basement membrane as an albumin barrier. J. Clin. Invest. 116, 2272-2279 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2272-2279
-
-
Jarad, G.1
Cunningham, J.2
Shaw, A.S.3
Miner, J.H.4
-
17
-
-
0842280714
-
Dynamic (re) organization of the podocyte actin cytoskeleton in the nephrotic syndrome
-
Oh, J., reiser, J. & Mundel, P Dynamic (re) organization of the podocyte actin cytoskeleton in the nephrotic syndrome. Pediatr. Nephrol. 19, 130-137 (2004).
-
(2004)
Pediatr. Nephrol.
, vol.19
, pp. 130-137
-
-
Oh, J.1
Reiser, J.2
Mundel, P.3
-
18
-
-
0029855437
-
A3(31 integrin has a crucial role in kidney and lung organogenesis
-
Kreidberg, J. A. et al. a3(31 integrin has a crucial role in kidney and lung organogenesis. Development 122, 3537-3547 (1996).
-
(1996)
Development
, vol.122
, pp. 3537-3547
-
-
Kreidberg, J.A.1
-
19
-
-
33749551723
-
Kidney failure in mice lacking the tetraspanin CD151
-
Sachs, N. et al. Kidney failure in mice lacking the tetraspanin CD151. J. Cell Biol. 175, 33-39 (2006).
-
(2006)
J. Cell Biol.
, vol.175
, pp. 33-39
-
-
Sachs, N.1
-
20
-
-
41149083878
-
31 integrin expression by podocytes is required to maintain glomerular structural integrity
-
Pozzi, A. et al. (31 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev. Biol. 316, 288-301 (2008).
-
(2008)
Dev. Biol.
, vol.316
, pp. 288-301
-
-
Pozzi, A.1
-
21
-
-
37849026460
-
Integrin (31-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus
-
Kanasaki, K. et al. Integrin (31-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev. Biol. 313, 584-593 (2008).
-
(2008)
Dev. Biol.
, vol.313
, pp. 584-593
-
-
Kanasaki, K.1
-
22
-
-
17144464384
-
Recombinant human laminin-10 (a5(51-y1). Production, purification, and migration-promoting activity on vascular endothelial cells
-
Doi, M. et al. recombinant human laminin-10 (a5(51-y1). Production, purification, and migration-promoting activity on vascular endothelial cells. J. Biol. Chem. 277, 12741-12748 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12741-12748
-
-
Doi, M.1
-
23
-
-
33746491157
-
Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling
-
Dai, C. et al. essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling. J. Am. Soc. Nephrol. 17, 2164-2175 (2006)
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 2164-2175
-
-
Dai, C.1
-
24
-
-
33646356720
-
Podocyte-specific deletion of ntegrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis
-
el-Aouni, C. et al. Podocyte-specific deletion of ntegrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis. J. Am. Soc. Nephrol. 17, 1334-1344 (2006).
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 1334-1344
-
-
El-Aouni, C.1
-
25
-
-
33645807621
-
Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins
-
Cohen, C. D. et al. Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins. Proc. Natl Acad. Sci. USA 103, 5682-5687 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 5682-5687
-
-
Cohen, C.D.1
-
26
-
-
0030669469
-
Precocious mammary gland development in P-cadherin-deficient mice
-
radice, G. L. et al. Precocious mammary gland development in P-cadherin-deficient mice. J. Cell Biol. 139, 1025-1032 (1997).
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1025-1032
-
-
Radice, G.L.1
-
27
-
-
33646406847
-
Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise nteraction of CD2AP Fyn, and synaptopodin
-
Huber, T. B. et al. Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise nteraction of CD2AP Fyn, and synaptopodin. J. Clin. Invest. 116, 1337-1345 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1337-1345
-
-
Huber, T.B.1
-
28
-
-
33645746950
-
Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes
-
Jones, N. et al. Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature 440, 818-823 (2006)
-
(2006)
Nature
, vol.440
, pp. 818-823
-
-
Jones, N.1
-
29
-
-
33646401549
-
Nephrin ectodomain engagement results in src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
-
Verma, R. et al. Nephrin ectodomain engagement results in src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J. Clin. Invest. 116, 1346-1359 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1346-1359
-
-
Verma, R.1
-
30
-
-
58149105312
-
Association of genetic variants at 3q22 with nephropathy in patients with type 1 diabetes mellitus
-
He, B. et al. Association of genetic variants at 3q22 with nephropathy in patients with type 1 diabetes mellitus. Am. J. Hum. Genet. 84, 5-13 (2009).
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 5-13
-
-
He, B.1
-
31
-
-
37549036286
-
Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization
-
Garg, P, verma, r., Nihalani, D., Johnstone, D. B. & Holzman, L. B. Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization. Mol. Cell. Biol. 27, 8698-8712 (2007).
-
(2007)
Mol. Cell. Biol.
, Issue.27
, pp. 8698-8712
-
-
Garg, P.1
Verma, R.2
Nihalani, D.3
Johnstone, D.B.4
Holzman, L.B.5
-
32
-
-
22844436647
-
TrPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
-
Reiser, J. et al. TrPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat. Genet. 37, 739-744 (2005)
-
(2005)
Nat. Genet.
, vol.37
, pp. 739-744
-
-
Reiser, J.1
-
33
-
-
20844461826
-
A mutation in the TrPC6 cation channel causes familial focal segmental glomerulosclerosis
-
Winn, M. P et al. A mutation in the TrPC6 cation channel causes familial focal segmental glomerulosclerosis. Science 308, 1801-1804 (2005).
-
(2005)
Science
, vol.308
, pp. 1801-1804
-
-
Winn, M.P.1
-
34
-
-
23344454472
-
-/- mice
-
Dietrich, A. et al. increased vascular smooth muscle contractility in TrPC6-/-mice. Mol. Cell. Biol. 25, 6980-6989 (2005).
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6980-6989
-
-
Dietrich, A.1
-
35
-
-
33846028228
-
Induction of TrPC6 channel in acquired forms of proteinuric kidney disease
-
Moller, C. C. et al. induction of TrPC6 channel in acquired forms of proteinuric kidney disease. J. Am. Soc. Nephrol. 18, 29-36 (2007).
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 29-36
-
-
Moller, C.C.1
-
36
-
-
33751531864
-
Positional cloning uncovers mutations in PLCe1 responsible for a nephrotic syndrome variant that may be reversible
-
Hinkes, B. et al. Positional cloning uncovers mutations in PLCe1 responsible for a nephrotic syndrome variant that may be reversible. Nat. Genet. 38, 1397-1405 (2006).
-
(2006)
Nat. Genet.
, vol.38
, pp. 1397-1405
-
-
Hinkes, B.1
-
37
-
-
33644696693
-
Phospholipase C epsilon modulates β-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy
-
Wang, H. et al. Phospholipase C epsilon modulates β-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy. Circ. Res. 97, 1305-1313 (2005).
-
(2005)
Circ. Res.
, vol.97
, pp. 1305-1313
-
-
Wang, H.1
-
38
-
-
52949092735
-
MYH9 is associated with nondiabetic end-stage renal disease in African Americans
-
Kao, w. H. et al. MYH9 is associated with nondiabetic end-stage renal disease in African Americans. Nat. Genet. 40, 1185-1192 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1185-1192
-
-
Kao, W.H.1
-
39
-
-
52949110955
-
MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis
-
Kopp, J. B. et al. MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis. Nat. Genet. 40, 1175-1184 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1175-1184
-
-
Kopp, J.B.1
-
40
-
-
4744364577
-
Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain ii-A in mice
-
Conti, M. A., even-ram, s., Liu, C., Yamada, K. M. & Adelstein, r. s. Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain ii-A in mice. J. Biol. Chem. 279, 41263-41266 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41263-41266
-
-
Conti, M.A.1
Even-Ram, S.2
Liu, C.3
Yamada, K.M.4
Adelstein, R.S.5
-
41
-
-
0036138503
-
Expression of the nonmuscle myosin heavy chain iiA in the human kidney and screening for MYH9 mutations in epstein and Fechtner syndromes
-
Arrondel, C. et al. expression of the nonmuscle myosin heavy chain iiA in the human kidney and screening for MYH9 mutations in epstein and Fechtner syndromes. J. Am. Soc. Nephrol. 13, 65-74 (2002)
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 65-74
-
-
Arrondel, C.1
-
42
-
-
38049032013
-
Modification of kidney barrier function by the urokinase receptor
-
wei, C. et al. Modification of kidney barrier function by the urokinase receptor. Nat. Med. 14, 55-63 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 55-63
-
-
Wei, C.1
-
43
-
-
40449112321
-
The Notch pathway in podocytes plays a role in the development of glomerular disease
-
Niranjan, T. et al. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat. Med. 14, 290-298 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 290-298
-
-
Niranjan, T.1
-
44
-
-
34247535480
-
Glomerulus-specific mrNA transcripts and proteins identified through kidney expressed sequence tag database analysis
-
He, L. et al. Glomerulus-specific mrNA transcripts and proteins identified through kidney expressed sequence tag database analysis. Kidney Int. 71, 889-900 (2007).
-
(2007)
Kidney Int.
, vol.71
, pp. 889-900
-
-
He, L.1
-
45
-
-
33947232065
-
Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066e14rik
-
Patrakka, J. et al. expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066e14rik. J. Am. Soc. Nephrol. 18, 689-697 (2007).
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 689-697
-
-
Patrakka, J.1
-
46
-
-
33644863418
-
Large-scale identification of genes implicated in kidney glomerulus development and function
-
Takemoto, M. et al. Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J. 25, 1160-1174 (2006).
-
(2006)
EMBO J.
, vol.25
, pp. 1160-1174
-
-
Takemoto, M.1
-
47
-
-
63249092534
-
Enhanced expression of Janus kinase-signal tranducer and activator of transcription pathway members in human diabetic nephropathy
-
Berthier, C. C. et al. enhanced expression of Janus kinase-signal tranducer and activator of transcription pathway members in human diabetic nephropathy. Diabetes 58, 469-477 (2009).
-
(2009)
Diabetes
, vol.58
, pp. 469-477
-
-
Berthier, C.C.1
-
48
-
-
51349162919
-
The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.
-
Faul, C. et al. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat. Med. 14, 931-938 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 931-938
-
-
Faul, C.1
|