Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin

Toxicology and Applied Pharmacology

Volumn 231, Issue 3, 2008, Pages 374-383

  Nishimura, Noriko ^a   Matsumura, Fumio ^b   Vogel, Christopher F A ^b   Nishimura, Hisao ^c   Yonemoto, Junzo ^a   Yoshioka, Wataru ^d   Tohyama, Chiharu ^a,d  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Aichi Mizuho College   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

2,3,7,8 tetrachlorodibenzo p dioxin; Cyclooxygenase 2; Hydronephrosis; Inflammation; Lactational exposure

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; COTRANSPORTER; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYTOKINE; DIOXIN; ELECTROLYTE; INTERLEUKIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; POTASSIUM ION; PROSTAGLANDIN E2; RENAL OUTER MEDULLARY POTASSIUM CHANNEL; SODIUM ION; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONGENITAL HYDRONEPHROSIS; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; HEREDITY; HYDRONEPHROSIS; LACTATION; MALE; MESENCHYME; MOUSE; NONHUMAN; PATHOGENESIS; PATHOLOGICAL ANATOMY; PERINATAL PERIOD; PRENATAL EXPOSURE; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; UPREGULATION; URETER OBSTRUCTION;

ANIMALS; ANIMALS, SUCKLING; CYCLOOXYGENASE 2; DIOXINS; ENZYME ACTIVATION; FEMALE; HYDRONEPHROSIS; LACTATION; MALE; MATERNAL EXPOSURE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PREGNANCY; TETRACHLORODIBENZODIOXIN;

MUS; RODENTIA;

EID: 50849112720     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.05.012     Document Type: Article

References (48)

1. Abbott B.D., and Birnbaum L.S. Effects of TCDD on embryonic ureteric epithelial EGF receptor expression and cell proliferation. Teratology 41 (1990) 71-84
2. Abbott B.D., Birnbaum L.S., and Pratt R.M. TCDD-induced hyperplasia of the ureteral epithelium produces hydronephrosis in murine fetuses. Teratology 35 (1987) 329-334
3. Airik R., Bussen M., Singh M.K., Petry M., and Kispert A. Tbx18 regulates the development of the ureteral mesenchyme. J. Clin. Invest. 116 (2006) 663-674
4. Belarmino J.M., and Kogan B.A. Management of neonatal hydronephrosis. Early Hum. Dev. 82 (2006) 9-14
5. Birnbaum L.S., Weber H., Harris M.W., Lamb J.C.T., and McKinney J.D. Toxic interaction of specific polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin: increased incidence of cleft palate in mice. Toxicol. Appl. Pharmacol. 77 (1985) 292-302
6. Bonnardeaux A., and Bichet D.G. Inherited disorders of the renal tubule. In: Brenner B.M. (Ed). Brenner and Rector's The Kidney (2004), Saunders, Philadelphia 1697-1741
7. Bryant P.L., Schmid J.E., Fenton S.E., Buckalew A.R., and Abbott B.D. Teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the expression of EGF and/or TGF-alpha. Toxicol. Sci. 62 (2001) 103-114
8. Chevalier R.L. Biomarkers of congenital obstructive nephropathy: past, present and future. J. Urol. 172 (2004) 852-857
9. Couture-Haws L., Harris M.W., McDonald M.M., Lockhart A.C., and Birnbaum L.S. Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery. Toxicol. Appl. Pharmacol. 107 (1991) 413-428
10. Degner S.C., Kemp M.Q., Hockings J.K., and Romagnolo D.F. Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer mcf-7 cells: repressive effects of conjugated linoleic acid. Nutr. Cancer 59 (2007) 248-257
11. Diaz A., Chepenik K.P., Korn J.H., Reginato A.M., and Jimenez S.A. Differential regulation of cyclooxygenases 1 and 2 by interleukin-1 beta, tumor necrosis factor-alpha, and transforming growth factor-beta 1 in human lung fibroblasts. Exp. Cell Res. 241 (1998) 222-229
12. Fernandez-Llama P., Ecelbarger C.A., Ware J.A., Andrews P., Lee A.J., Turner R., Nielsen S., and Knepper M.A. Cyclooxygenase inhibitors increase Na-K-2Cl cotransporter abundance in thick ascending limb of Henle's loop. Am. J. Physiol. 277 (1999) F219-226
13. Gasiewicz T.A., and Park S. Ah receptor: involvement in toxic responses. In: Schecter A., and Gasiewicz T.A. (Eds). Dioxins and Health (2003), John Wiley & Sons, Hoboken, N.J. USA 491-532
14. Grasso M., and Gitlin J.S. Ureteropelvic junction obstruction. eMedicine (2006). http://www.emedicine.com/med/topic3074.htm
15. Herschman H.R. Prostaglandin synthase 2. Biochim. Biophys. Acta 1299 (1996) 125-140
16. Jin Y., Wang Z., Zhang Y., Yang B., and Wang W.H. PGE2 inhibits apical K channels in the CCD through activation of the MAPK pathway. Am. J. Physiol., Renal Physiol. 293 (2007) F1299-1307
17. Kaji D.M., Chase Jr. H.S., Eng J.P., and Diaz J. Prostaglandin E2 inhibits Na-K-2Cl cotransport in medullary thick ascending limb cells. Am. J. Physiol. 271 (1996) C354-361
18. Kang Y.J., Wingerd B.A., Arakawa T., and Smith W.L. Cyclooxygenase-2 gene transcription in a macrophage model of inflammation. J. Immunol. 177 (2006) 8111-8122
19. Lang R.J., Davidson M.E., and Exintaris B. Pyeloureteral motility and ureteral peristalsis: essential role of sensory nerves and endogenous prostaglandins. Exp. Physiol. 87 (2002) 129-146
20. Lorenz J.N., Baird N.R., Judd L.M., Noonan W.T., Andringa A., Doetschman T., Manning P.A., Liu L.H., Miller M.L., and Shull G.E. Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome. J. Biol. Chem. 277 (2002) 37871-37880
21. Lu M., Wang T., Yan Q., Yang X., Dong K., Knepper M.A., Wang W., Giebisch G., Shull G.E., and Hebert S.C. Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J. Biol. Chem. 277 (2002) 37881-37887
22. Madsen K.M., and Tisher C.C. Anatomy of the kidney. In: Brenner B.M. (Ed). Brenner and Rector's The Kidney (2004), Saunders, Philadelphia 17-19
23. Mahoney Z.X., Sammut B., Xavier R.J., Cunningham J., Go G., Brim K.L., Stappenbeck T.S., Miner J.H., and Swat W. Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 19872-19877
24. Matsumura F. On the significance of the role of cellular stress response reactions in the toxic actions of dioxin. Biochem. Pharmacol. 66 (2003) 527-540
25. McDill B.W., Li S.Z., Kovach P.A., Ding L., and Chen F. Congenital progressive hydronephrosis (cph) is caused by an S256L mutation in aquaporin-2 that affects its phosphorylation and apical membrane accumulation. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 6952-6957
26. Mimura J., Yamashita K., Nakamura K., Morita M., Takagi T.N., Nakao K., Ema M., Sogawa K., Yasuda M., Katsuki M., and Fujii-Kuriyama Y. Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Genes Cells 2 (1997) 645-654
27. Nie M., Pang L., Inoue H., and Knox A.J. Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation. Mol. Cell. Biol. 23 (2003) 9233-9244
28. Nishimura N., Miyabara Y., Sato M., Yonemoto J., and Tohyama C. Immunohistochemical localization of thyroid stimulating hormone induced by a low oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats. Toxicology 171 (2002) 73-82
29. Nishimura N., Yonemoto J., Miyabara Y., Sato M., and Tohyama C. Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Endocrinology 144 (2003) 2075-2083
30. Nishimura N., Yonemoto J., Nishimura H., Ikushiro S., and Tohyama C. Disruption of thyroid hormone homeostasis at weaning of Holtzman rats by lactational but not in utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 85 (2005) 607-614
31. Nishimura N., Yonemoto J., Nishimura H., and Tohyama C. Localization of cytochrome P450 1A1 in a specific region of hydronephrotic kidney of rat neonates lactationally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology 227 (2006) 117-126
32. Nusing R.M., Treude A., Weissenberger C., Jensen B., Bek M., Wagner C., Narumiya S., and Seyberth H.W. Dominant role of prostaglandin E2 EP4 receptor in furosemide-induced salt-losing tubulopathy: a model for hyperprostaglandin E syndrome/antenatal Bartter syndrome. J. Am. Soc. Nephrol. 16 (2005) 2354-2362
33. Ohama T., Hori M., Momotani E., Elorza M., Gerthoffer W.T., and Ozaki H. IL-1beta inhibits intestinal smooth muscle proliferation in an organ culture system: involvement of COX-2 and iNOS induction in muscularis resident macrophages. Am. J. Physiol.: Gasterointest. Liver Physiol. 292 (2007) G1315-1322
34. Pang L., Holland E., and Knox A.J. Role of cyclo-oxygenase-2 induction in interleukin-1beta induced attenuation of cultured human airway smooth muscle cell cyclic AMP generation in response to isoprenaline. Br. J. Pharmacol. 125 (1998) 1320-1328
35. Peters J.M., Narotsky M.G., Elizondo G., Fernandez-Salguero P.M., Gonzalez F.J., and Abbott B.D. Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice. Toxicol. Sci. 47 (1999) 86-92
36. Puga A., Hoffer A., Zhou S., Bohm J.M., Leikauf G.D., and Shertzer H.G. Sustained increase in intracellular free calcium and activation of cyclooxygenase-2 expression in mouse hepatoma cells treated with dioxin. Biochem. Pharmacol. 54 (1997) 1287-1296
37. Takahashi N., Chernavvsky D.R., Gomez R.A., Igarashi P., Gitelman H.J., and Smithies O. Uncompensated polyuria in a mouse model of Bartter's syndrome. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 5434-5439
38. Theobald H.M., Kimmel G.L., and Peterson R.E. Developmental and reproductive toxicity of dioxins and related chemicals. In: Schecter A., and Gasiewicz T.A. (Eds). Dioxins and Health (2003), Wily-Interscience, Hoboken, N.J., USA 329-432
39. Thomae T.L., Stevens E.A., Liss A.L., Drinkwater N.R., and Bradfield C.A. The teratogenic sensitivity to 2,3,7,8-tetrachlorodibenzo-p-dioxin is modified by a locus on mouse chromosome 3. Mol. Pharmacol. 69 (2006) 770-775
40. Uribarri J., and Kaskas M. Hereditary nephrogenic diabetes insipidus and bilateral nonobstructive hydronephrosis. Nephron 65 (1993) 346-349
41. Vogel C., Boerboom A.M., Baechle C., El-Bahay C., Kahl R., Degen G.H., and Abel J. Regulation of prostaglandin endoperoxide H synthase-2 induction by dioxin in rat hepatocytes: possible c-Src-mediated pathway. Carcinogenesis 21 (2000) 2267-2274
42. Vogel C., Schuhmacher U.S., Degen G.H., Bolt H.M., Pineau T., and Abel J. Modulation of prostaglandin H synthase-2 mRNA expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice. Arch. Biochem. Biophys. 351 (1998) 265-271
43. Vogel C.F., Nishimura N., Sciullo E., Wong P., Li W., and Matsumura F. Modulation of the chemokines KC and MCP-1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice. Arch. Biochem. Biophys. 461 (2007) 169-175
44. Walch L., and Morris P.L. Cyclooxygenase 2 pathway mediates IL-1beta regulation of IL-1alpha, -1beta, and IL-6 mRNA levels in Leydig cell progenitors. Endocrinology 143 (2002) 3276-3283
45. Yang T. Regulation of cyclooxygenase-2 in renal medulla. Acta Physiol. Scand. 177 (2003) 417-421
46. Yun J., Schoneberg T., Liu J., Schulz A., Ecelbarger C.A., Promeneur D., Nielsen S., Sheng H., Grinberg A., Deng C., and Wess J. Generation and phenotype of mice harboring a nonsense mutation in the V2 vasopressin receptor gene. J. Clin. Invest. 106 (2000) 1361-1371
47. Zeidel M.L., and Pirtskhalaishvili G. Urinary tract obstruction. In: Brenner B.M. (Ed). Brenner and Rector's The Kidney (2004), Saunders, Philadelphia 1867-1894
48. Zender H.O., Ruedin P., Moser F., Bolle J.F., and Leski M. Traumatic rupture of the urinary tract in a patient presenting nephrogenic diabetes insipidus associated with hydronephrosis and chronic renal failure: case report and review of the literature. Clin. Nephrol. 38 (1992) 196-202