Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts

Free Radical Biology and Medicine

Volumn 76, Issue , 2014, Pages 136-146

  Goto, Masanori ^a,b   Shinmura, Kazuya ^b   Matsushima, Yoshitaka ^b   Ishino, Kousuke ^a,c   Yamada, Hidetaka ^b   Totsuka, Yukari ^a   Matsuda, Tomonari ^d   Nakagama, Hitoshi ^a   Sugimura, Haruhiko ^b  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NIPPON MEDICAL SCHOOL   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

3N4 Ethenocytosine; Base excision repair enzyme; Etheno DNA adducts; Lipid peroxidation; TDG

Indexed keywords

1,N6 ETHENOADENINE; 3,N4 ETHENOCYTOSINE; BUTANONE ETHENOCYTOSINE; BUTANONE ETHENOGUANINE; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; HEPTANONE ETHENOCYTOSINE; HEPTANONE ETHENOGUANINE; OLIGONUCLEOTIDE; PROTEIN MPG; PROTEIN NEIL1; PROTEIN NTH1; PROTEIN OGG1; PROTEIN SMUG1; PROTEIN TDG; PROTEIN UNG2; THYMINE; UNCLASSIFIED DRUG; DNA ADDUCT; ETHYLENE; ETHYLENE DERIVATIVE; THYMINE DNA GLYCOSYLASE;

ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DNA ADDUCT; DNA CLEAVAGE; ENZYME ACTIVITY; EXCISION REPAIR; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPID PEROXIDATION; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; PROTEIN EXPRESSION; REACTION TIME; CELL CULTURE; CHEMISTRY; DNA REPAIR; ENZYME SPECIFICITY; METABOLISM;

CELL SURVIVAL; CELLS, CULTURED; DNA ADDUCTS; DNA REPAIR; ETHYLENES; HUMANS; LIPID PEROXIDATION; SUBSTRATE SPECIFICITY; THYMINE; THYMINE DNA GLYCOSYLASE;

EID: 84907206604     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.07.044     Document Type: Article

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