Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo

Carcinogenesis

Volumn 24, Issue 6, 2003, Pages 1031-1037

  Yamane, Arito ^a   Shinmura, Kazuya ^a   Sunaga, Noriaki ^a   Saitoh, Takayuki ^a,b   Yamaguchi, Satoru ^a   Shinmura, Yumi ^a   Yoshimura, Kimio ^a   Murakami, Hirokazu ^b   Nojima, Yoshihisa ^b   Kohno, Takashi ^a   Yokota, Jun ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; ADENINE; BENZO[A]PYRENE; CIGARETTE SMOKE; DIHYDROXYBENZO[A]PYRENE OXIDE; DNA; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE; GUANINE; LYASE; PROTEIN MYH; PROTEIN OGG1; THYMINE; TRANSFER RNA; UNCLASSIFIED DRUG;

CANCER CELL CULTURE; CONTROLLED STUDY; EXCISION REPAIR; GENE MUTATION; GENE OVEREXPRESSION; GENE REPLICATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG CANCER; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; PLASMID; PRIORITY JOURNAL; REVIEW;

EID: 0038011261     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg056     Document Type: Review

References (41)

1. Bennett,W.P., Hussain,S.P., Vahakangas,K.H., Khan,M.A., Shields,P.G. and Harris,C.C. (1999) Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer. J. Pathol., 187, 8-18.
2. Hainaut,P. and Pfeifer,G.P. (2001) Patterns of p53 G → T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. Carcinogenesis, 22, 367-374.
3. Kasai,H. (1997) Analysis of a form of oxidative DNA damage, 8-dydroxy-2′-deoxyguanosine, as a marker of oxidative stress during carcinogenesis. Mutat. Res., 387, 147-163.
4. Rubin,H. (2001) Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates. Carcinogenesis, 22, 1903-1930.
5. Shibutani,S., Takeshita,M. and Grollman,A.P. (1991) Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature, 349, 431-434.
6. Lindahl,T. and Wood,R.D. (1999) Quality control by DNA repair. Science, 286, 1897-1905.
7. Hoeijmakers,J.H. (2001) Genome maintenance mechanisms for preventing cancer. Nature, 411, 366-374.
8. Boiteux,S. and Radicella,J.P. (2000) The human OGG1 gene: structure functions, and its implication in the process of carcinogenesis. Arch. Biochem. Biophys., 377, 1-8.
9. Page,F.L., Kwoh,E.E., Avrutskaya,A., Gentil,A., Leadon,S.A., Sarasin,A. and Cooper,P.K. (2000) Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome. Cell, 101, 159-171.
10. Shinmura,K. and Yokota,J. (2001) The OGG1 gene encodes a repair enzyme for oxidatively damaged DNA and is involved in human carcinogenesis. Antiox. Redox Signal., 3, 597-609.
11. Slupska,M.M., Luther,W.M., Chiang,J.H., Yang,H. and Miller,J.H. (1999) Functional expression of hMYH, a human homolog of the Escherichia coli MutY protein. J. Bacteriol., 181, 6210-6213.
12. Shinmura,K., Yamaguchi,S., Saitoh,T., Takeuchi-Sasaki,M., Kim,S.-R., Nohmi,T. and Yokota,J. (2000) Adenine excisional repair function of MYH protein on the adenine: 8-hydroxyguanine base pair in double-stranded DNA. Nucleic Acids Res., 28, 4912-4918.
13. Evans,A.R., Limp-Foster,M. and Kelley,M.R. (2000) Going APE over ref-1. Mutat. Res., 461, 83-108.
14. Wilson,D.M. 3rd and Barsky,D. (2001) The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. Mutat. Res., 485, 283-307.
15. Hill,J.W., Hazra,T.K., Izumi,T. and Mitra,S. (2001) Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair. Nucleic Acids Res., 29, 430-438.
16. Saitoh,T., Shinmura,K., Yamaguchi,S., Tani,M., Seki,S., Murakami,H., Nojima,Y. and Yokota,J. (2001) Enhancement of OGG1 protein AP lyase activity by increase of APEX protein. Mutat. Res., 486, 31-40.
17. Vidal,A.E., Hickson,I.D., Boiteux,S. and RadicellaJ.P. (2001) Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step. Nucleic Acids Res., 29, 1285-1292.
18. Sunaga,N., Kohno,T., Shinmura,K., Saitoh,T., Matsuda,T., Saito,R. and Yokota,J. (2001) OGG1 protein suppresses G:C to T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells. Carcinogenesis, 22, 1355-1362.
19. Yang,J.-L., Maher,V.M. and McCormick,J.J. (1987) Kinds of mutations formed when a shuttle vector containing adducts of (±)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetra- hydrobenzo[a]pyrene replicates in human cells. Proc. Natl Acad. Sci. USA, 84, 3787-3791.
20. Roilides,E., Gielen,J.E., Tuteja,N., Levine,A.S. and Dixon,K. (1988) Mutational specificity of benzo[a]pyrene diolepoxide in monkey cells. Mutat. Res., 198, 199-206.
21. Hussain,S.P., Amstad,P., Raja,K., Sawyer,M., Hofseth,L., Shields,P.G., Hewer,A., Phillips,D.H., Ryberg,D., Haugen,A. and Harris,C.C. (2001) Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung. Cancer Res., 61, 6350-6355.
22. Blakey,D.H. and Douglas,G.R. (1990) The role of excision repair in the removal of transient benzo[a]pyrene-induced DNA lesions in Chinese hamster ovary cells. Mutat. Res., 236, 35-41.
23. Gunz,D., Hess,M.T. and Naegeli,H. (1996) Recognition of DNA adducts by human nucleotide excision repair. Evidence for a thermodynamic probing mechanism. J. Biol. Chem., 271, 25089-25098.
24. Braithwaite,E., Wu,X. and Wang,Z. (1998) Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: involvement of two excision repair mechanisms in vitro. Carcinogenesis, 19, 1239-1246.
25. Matsuda,T., Kawanishi,M., Yagi,T., Matsui,S. and Takebe,H. (1998) Specific tandem GG to TT base substitutions induced by acetaldehyde are due to intra-strand crosslinks between adjacent guanine bases. Nucleic Acids Res., 26, 1769-1774.
26. Yamaguchi,S., Shimnura,K., Saitoh,T., Takenoshita,S., Kuwano,H. and Yokota,J. (2002) A single nucleotide polymorphism at the splice donor site of the human MYH base excision repair genes results in reduced translation efficiency of its transcripts. Genes Cells, 7, 461-474.
27. Seki,S., Hatsushika,M., Watanabe,S., Akiyama,K., Nagao,K. and Tsutsui,K. (1992) cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III. Biochim. Biophys. Acta, 1131, 287-299.
28. Shinmura,K., Kohno,T., Takeuchi-Sasaki,M., Maeda,M., Segawa,T., Kamo,T., Sugimura,H. and Yokota,J. (2000) Expression of the OGG1-type 1a (nuclear form) protein in cancerous and non-cancerous human cells. Int. J. Oncol., 16, 701-707.
29. Klein,J.C., Bleeker,M.J., Saris,C.P. et al. (1992) Repair and replication of plasmids with site-specific 8-oxodG and 8-AAFdG residues in normal and repair-deficient human cells. Nucleic Acids Res., 20, 4437-4443.
30. Kamiya,H., Murata-Kamiya,N., Koizume,S., Inoue,H., Nishimura,S. and Ohtsuka,E. (1995) 8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene. Carcinogenesis, 16, 883-889.
31. Courtemanche,C. and Anderson,A. (1999) The p53 tumor suppressor protein reduces point mutation frequency of a shuttle vector modified by the chemical mutagens (+/-)7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, aflatoxin B1 and meta-chloroperoxybenzoic acid. Oncogene, 18, 4672-4680.
32. Routledge,M.N., McLuckie,K.I., Jones,G.D., Farmer,P.B. and Martin,E.A. (2001) Presence of benzo[a]pyrene diol epoxide adducts in target DNA leads to an increase in UV-induced DNA single strand breaks and supF gene mutations. Carcinogenesis, 22, 1231-1238.
33. Kohno,T., Shinmura,K., Tosaka,M., Tani,M., Kim,S.R., Sugimura,H., Nohmi,T., Kasai,H. and Yokota,J. (1998) Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA. Oncogene, 16, 3219-3225.
34. Shinmura,K., Yamaguchi,S., Saitoh,T., Kohno,T. and Yokota,J. (2001) Somatic mutations and single nucleotide polymorphisms of base excision repair genes involved in the repair of 8-hydroxyguanine in damaged DNA. Cancer Lett., 166, 65-69.
35. Sugimura,H., Kohno,T., Wakai,K. et al. (1999) hOGG1 Ser326Cys polymorphism and lung cancer susceptibility. Cancer Epidemiol. Biomarkers Prev., 8, 669-674.
36. Wikman,H., Risch,A., Klimek,F., Schmezer,P., Spiegelhalder,B., Dienemann,H., Kayser,K., Schulz,V., Drings,P. and Bartsch,H. (2000) hOGG1 polymorphism and loss of heterozygosity (LOH): significance for lung cancer susceptibility in a Caucasian population. Int. J. Cancer, 88, 932-937.
37. Xing,D.Y., Tan,W., Song,N. and Lin,D.X. (2001) Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population. Int. J. Cancer, 95, 140-143.
38. Elahi,A., Zheng,Z., Park,J., Eyring,K., McCaffrey,T. and Lazarus,P. (2002) The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis, 23, 1229-1234.
39. Le Marchand,L., Donlon,T., Lum-Jones,A., Seifried,A. and Wilkens,L.R. (2002) Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk. Cancer Epidemiol. Biomarkers Prev., 11, 409-412.
40. Xu,J., Zheng,S.L., Turner,A. et al. (2002) Associations between hOGG1 sequence variants and prostate cancer susceptibility. Cancer Res., 62, 2253-2257.
41. Al-Tassan,N., Chmiel,N.H., Maynard,J. et al. (2002) Inherited variants of MYH associated with somatic G:C → T:A mutations in colorectal tumors. Nature-Genet., 30, 227-232.