Acute regulation of PDK1 by a complex interplay of molecular switches

Biochemical Society Transactions

Volumn 42, Issue 5, 2014, Pages 1435-1440

  Calleja, Veronique ^a   Laguerre, Michel ^b   De Las Heras Martinez, Gloria ^c   Parker, Peter J ^a,d   Requejo Isidro, Jose ^c   Larijani, Banafshé ^a,e,f  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e BASQUE FOUNDATION FOR SCIENCE   (Spain)

^f CSIC UPV Unidad de Biofisica UBF   (Spain)

Author keywords

Activation dynamics; Homodimerization; Phosphoinositide dependent kinase 1 (pdk1); Phosphorylation; Subcellular localization

Indexed keywords

HOMODIMER; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; 3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE; LIGAND; PDPK1 PROTEIN, HUMAN; SERINE; THREONINE; TUMOR PROTEIN; TYROSINE;

CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; DIMERIZATION; ENZYME ACTIVATION; ENZYME BINDING; ENZYME PHOSPHORYLATION; HUMAN; NONHUMAN; PROTEIN PHOSPHORYLATION; REVIEW; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES; ANIMALS; DIMERIZATION; ENZYME ACTIVATION; HUMANS; LIGANDS; MODELS, MOLECULAR; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; SERINE; SIGNAL TRANSDUCTION; THREONINE; TYROSINE;

EID: 84907195505     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20140222     Document Type: Review

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