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Volumn 61, Issue , 2014, Pages 181-191

Advances in liquid chromatography coupled to mass spectrometry for metabolic phenotyping

Author keywords

Global metabolic profiling; Hydrophilic interaction chromatography; Liquid chromatography; Mass spectrometry; Metabolic phenotyping; Metabolomics; Metabonomics; Reversed phase liquid chromatography; Ultra high performance liquid chromatography; Ultra performance liquid chromatography

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; SEPARATION;

EID: 84907007695     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2014.06.005     Document Type: Review
Times cited : (55)

References (72)
  • 1
    • 0034634448 scopus 로고    scopus 로고
    • Based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL101J and Alpk:ApfCD mouse
    • Gavaghan C.L., Holmes E., Lenz E., Wilson I.D., Nicholson J.K., An N.M.R. Based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL101J and Alpk:ApfCD mouse. FEBS Lett 2000, 484:169-174.
    • (2000) FEBS Lett , vol.484 , pp. 169-174
    • Gavaghan, C.L.1    Holmes, E.2    Lenz, E.3    Wilson, I.D.4    Nicholson, J.K.5    An, N.M.R.6
  • 3
    • 33847358695 scopus 로고    scopus 로고
    • Analytical Strategies for Metabonomics
    • Lenz E.M., Wilson I.D. Analytical Strategies for Metabonomics. J. Proteome Res 2007, 6:443-458.
    • (2007) J. Proteome Res , vol.6 , pp. 443-458
    • Lenz, E.M.1    Wilson, I.D.2
  • 4
    • 67349149061 scopus 로고    scopus 로고
    • The application of chromatography-mass spectrometry: methods to metabonomics
    • Wu Z., Huang Z., Lehmann R., Zhao C., Xu G. The application of chromatography-mass spectrometry: methods to metabonomics. Chromatographia 2009, 69:S23-S32.
    • (2009) Chromatographia , vol.69 , pp. S23-S32
    • Wu, Z.1    Huang, Z.2    Lehmann, R.3    Zhao, C.4    Xu, G.5
  • 5
    • 84936943793 scopus 로고    scopus 로고
    • Cambridge, UK; RSC Chromatography Monographs 18, RSC, T. Hotylainen, S. Weidmer (Eds.)
    • Chromatography Methods in Metabolomics 2013, Cambridge, UK; RSC Chromatography Monographs 18, RSC. T. Hotylainen, S. Weidmer (Eds.).
    • (2013) Chromatography Methods in Metabolomics
  • 6
    • 84900035172 scopus 로고    scopus 로고
    • Recent developments in liquid-phase separation techniques for metabolomics
    • Ramautar R., de Jong G.J. Recent developments in liquid-phase separation techniques for metabolomics. Bioanalysis 2014, 6:1011-1026.
    • (2014) Bioanalysis , vol.6 , pp. 1011-1026
    • Ramautar, R.1    de Jong, G.J.2
  • 7
    • 79953302048 scopus 로고    scopus 로고
    • Metabolite analysis by supercritical fluid chromatography
    • Matsubara A., Fukusaki E., Bamba T. Metabolite analysis by supercritical fluid chromatography. Bioanalysis 2010, 2:27-34.
    • (2010) Bioanalysis , vol.2 , pp. 27-34
    • Matsubara, A.1    Fukusaki, E.2    Bamba, T.3
  • 8
    • 78650301750 scopus 로고    scopus 로고
    • CE-MS for metabolomics: developments and applications in the period 2008-2010
    • Ramautar R., Mayboroda O.A., Somsen G.W., de Jong G.J. CE-MS for metabolomics: developments and applications in the period 2008-2010. Electrophoresis 2011, 32:52-65.
    • (2011) Electrophoresis , vol.32 , pp. 52-65
    • Ramautar, R.1    Mayboroda, O.A.2    Somsen, G.W.3    de Jong, G.J.4
  • 9
    • 84889567618 scopus 로고    scopus 로고
    • Currrent practice of liquid chromatography-mass spectrometry in metabolomics and metabonomics
    • Gika H.G., Theodoridis G.A., Plumb R.S., Wilson I.D. Currrent practice of liquid chromatography-mass spectrometry in metabolomics and metabonomics. J. Pharm. Biomed. Anal 2014, 87:12-25.
    • (2014) J. Pharm. Biomed. Anal , vol.87 , pp. 12-25
    • Gika, H.G.1    Theodoridis, G.A.2    Plumb, R.S.3    Wilson, I.D.4
  • 10
    • 0036404889 scopus 로고    scopus 로고
    • Nontargeted metabolome analysis by use of fourier transform ion cyclotron mass spectrometry
    • Aharoni A., de Vos C.H.R., Verhoeven H.A., Maliepaard C.A., Kruppa G., Bino R., et al. Nontargeted metabolome analysis by use of fourier transform ion cyclotron mass spectrometry. OMICS 2002, 6:217-234.
    • (2002) OMICS , vol.6 , pp. 217-234
    • Aharoni, A.1    de Vos, C.H.R.2    Verhoeven, H.A.3    Maliepaard, C.A.4    Kruppa, G.5    Bino, R.6
  • 11
    • 33749535056 scopus 로고    scopus 로고
    • Predicting interpretability of metabolome models based on behavior, putative identity, and biological relevance of explanatory signals
    • Enot D.P., Beckmann M., Overy D., Draper J. Predicting interpretability of metabolome models based on behavior, putative identity, and biological relevance of explanatory signals. PNAS 2006, 103:14865-14870.
    • (2006) PNAS , vol.103 , pp. 14865-14870
    • Enot, D.P.1    Beckmann, M.2    Overy, D.3    Draper, J.4
  • 12
    • 42949111593 scopus 로고    scopus 로고
    • Direct introduction of biological samples into a LTQ-Orbitrap hybrid mass spectrometer as a tool for fast metabolome analysis
    • Madalinski G., Godat E., Alves S., Lesage D., Genin E., Levi P., et al. Direct introduction of biological samples into a LTQ-Orbitrap hybrid mass spectrometer as a tool for fast metabolome analysis. Anal. Chem 2008, 80:3291-3303.
    • (2008) Anal. Chem , vol.80 , pp. 3291-3303
    • Madalinski, G.1    Godat, E.2    Alves, S.3    Lesage, D.4    Genin, E.5    Levi, P.6
  • 13
    • 66749102638 scopus 로고    scopus 로고
    • Application of ultra performance liquid chromatography-mass spectrometry to profiling rat and dog bile
    • Plumb R.S., Rainville P.D., Potts W.B., Johnson K.A., Gika E., Wilson I.D. Application of ultra performance liquid chromatography-mass spectrometry to profiling rat and dog bile. J. Proteome Res 2009, 8:2495-2500.
    • (2009) J. Proteome Res , vol.8 , pp. 2495-2500
    • Plumb, R.S.1    Rainville, P.D.2    Potts, W.B.3    Johnson, K.A.4    Gika, E.5    Wilson, I.D.6
  • 14
    • 77954358805 scopus 로고    scopus 로고
    • Use of an atmospheric solids analysis probe (ASAP) for high throughput screening of biological fluids: preliminary applications on urine and bile
    • Twohig M., Shockcor J.P., Wilson I.D., Nicholson J.K., Plumb R.S. Use of an atmospheric solids analysis probe (ASAP) for high throughput screening of biological fluids: preliminary applications on urine and bile. J. Proteome Res 2010, 9:3590-3597.
    • (2010) J. Proteome Res , vol.9 , pp. 3590-3597
    • Twohig, M.1    Shockcor, J.P.2    Wilson, I.D.3    Nicholson, J.K.4    Plumb, R.S.5
  • 15
    • 28544448597 scopus 로고    scopus 로고
    • Analysis of solids, liquids, and biological tissues using solids probe introduction at atmospheric pressure on commercial LC/MS instruments
    • McEwan C.N., McKay R.G., Larsen B.S. Analysis of solids, liquids, and biological tissues using solids probe introduction at atmospheric pressure on commercial LC/MS instruments. Anal. Chem 2005, 77:7826-7831.
    • (2005) Anal. Chem , vol.77 , pp. 7826-7831
    • McEwan, C.N.1    McKay, R.G.2    Larsen, B.S.3
  • 16
    • 48949106229 scopus 로고    scopus 로고
    • An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry
    • Harry E.M., Weston D.J., Bristow A.W.T., Wilson I.D., Creaser C.S. An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry. J. Chromatogr. B 2008, 871:357-361.
    • (2008) J. Chromatogr. B , vol.871 , pp. 357-361
    • Harry, E.M.1    Weston, D.J.2    Bristow, A.W.T.3    Wilson, I.D.4    Creaser, C.S.5
  • 17
    • 17444404226 scopus 로고    scopus 로고
    • High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass Spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
    • Wilson I.D., Nicholson J.K., Castro-Perez J., Granger J.H., Johnson K., Smith B., et al. High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass Spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. J. Proteome Res 2005, 4:591-598.
    • (2005) J. Proteome Res , vol.4 , pp. 591-598
    • Wilson, I.D.1    Nicholson, J.K.2    Castro-Perez, J.3    Granger, J.H.4    Johnson, K.5    Smith, B.6
  • 18
    • 83055186403 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometry based global metabolite profiling: a review
    • Theodoridis G.A., Gika H.G., Want E.J., Wilson I.D. Liquid chromatography-mass spectrometry based global metabolite profiling: a review. Anal. Chim. Acta 2012, 711:7-16.
    • (2012) Anal. Chim. Acta , vol.711 , pp. 7-16
    • Theodoridis, G.A.1    Gika, H.G.2    Want, E.J.3    Wilson, I.D.4
  • 19
    • 34347255385 scopus 로고    scopus 로고
    • High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies
    • Granger J.H., Williams R., Lenz E.M., Plumb R.S., Stumpf C.L., Wilson I.D. High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. Rapid Commun. Mass Spectrom 2007, 21:2039-2045.
    • (2007) Rapid Commun. Mass Spectrom , vol.21 , pp. 2039-2045
    • Granger, J.H.1    Williams, R.2    Lenz, E.M.3    Plumb, R.S.4    Stumpf, C.L.5    Wilson, I.D.6
  • 20
    • 70350028279 scopus 로고    scopus 로고
    • Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS
    • Qiu Y., Cai G., Su M., Chen T., Zheng X., Xu Y., et al. Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS. J. Proteome Res 2009, 8:4844-4850.
    • (2009) J. Proteome Res , vol.8 , pp. 4844-4850
    • Qiu, Y.1    Cai, G.2    Su, M.3    Chen, T.4    Zheng, X.5    Xu, Y.6
  • 21
    • 84863042105 scopus 로고    scopus 로고
    • Metabonomic profiles discriminate hepatocellular carcinoma from liver cirrhosis by ultraperformance liquid chromatography-mass spectrometry
    • Wang B., Chen D., Chen Y., Hu Z., Cao M., Xie Q., et al. Metabonomic profiles discriminate hepatocellular carcinoma from liver cirrhosis by ultraperformance liquid chromatography-mass spectrometry. J. Proteome Res 2012, 11:1217-1227.
    • (2012) J. Proteome Res , vol.11 , pp. 1217-1227
    • Wang, B.1    Chen, D.2    Chen, Y.3    Hu, Z.4    Cao, M.5    Xie, Q.6
  • 22
    • 77956299196 scopus 로고    scopus 로고
    • Metabolic profiling of plasma in overweight/obese and lean men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC-Q-TOF MS)
    • Kim J.Y., Park J.Y., Kim O.Y., Ham B.M., Kim H.-J., Kwon D.Y., et al. Metabolic profiling of plasma in overweight/obese and lean men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC-Q-TOF MS). J. Proteome Res 2010, 9:4368-4375.
    • (2010) J. Proteome Res , vol.9 , pp. 4368-4375
    • Kim, J.Y.1    Park, J.Y.2    Kim, O.Y.3    Ham, B.M.4    Kim, H.-J.5    Kwon, D.Y.6
  • 25
    • 70349321699 scopus 로고    scopus 로고
    • A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry
    • Yin P., Wan D., Zhao C., Chen J., Zhao X., Wang W., et al. A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry. Mol. Biosyst 2009, 5:868-876.
    • (2009) Mol. Biosyst , vol.5 , pp. 868-876
    • Yin, P.1    Wan, D.2    Zhao, C.3    Chen, J.4    Zhao, X.5    Wang, W.6
  • 26
    • 84907016162 scopus 로고    scopus 로고
    • Application of UHPLC-MS to human metabolomic/metabonomic studies
    • RSC Chromatography Monographs 16, D. Guillarme, J.-L. VeutheyWan (Eds.)
    • Gika H.G., Theodoridis G., Wilson I.D. Application of UHPLC-MS to human metabolomic/metabonomic studies. UHPLC in Life Sciences 2012, 391. RSC Chromatography Monographs 16. D. Guillarme, J.-L. VeutheyWan (Eds.).
    • (2012) UHPLC in Life Sciences , pp. 391
    • Gika, H.G.1    Theodoridis, G.2    Wilson, I.D.3
  • 30
    • 28544450370 scopus 로고    scopus 로고
    • A new separation techniquetakes advantage of sub-2-μm porous particles
    • Mazzeo J.R., Neue U.D., Kele M., Plumb R.S. A new separation techniquetakes advantage of sub-2-μm porous particles. Anal. Chem 2005, 77:460-467A.
    • (2005) Anal. Chem , vol.77 , pp. 460-467A
    • Mazzeo, J.R.1    Neue, U.D.2    Kele, M.3    Plumb, R.S.4
  • 31
    • 21144435518 scopus 로고    scopus 로고
    • A rapid screening approach to metabonomics using UPLC and oa-TOFmass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice
    • Plumb R.S., Granger J.H., Stump C.L., Johnson K., Smith B.W., Gaulitz S., et al. A rapid screening approach to metabonomics using UPLC and oa-TOFmass spectrometry: application to age, gender and diurnal variation in normal/Zucker obese rats and black, white and nude mice. Analyst 2005, 130:844-849.
    • (2005) Analyst , vol.130 , pp. 844-849
    • Plumb, R.S.1    Granger, J.H.2    Stump, C.L.3    Johnson, K.4    Smith, B.W.5    Gaulitz, S.6
  • 32
    • 84862899475 scopus 로고    scopus 로고
    • Investigation of microbore UPLC and nontraditional mobile phase compositions for bioanalytical LC-MS/MS
    • Rainville P.D., Simeone J.L., McCarthy S.M., Smith N.W., Cowan D., Plumb R.S. Investigation of microbore UPLC and nontraditional mobile phase compositions for bioanalytical LC-MS/MS. Bioanalysis 2012, 4:1287-1297.
    • (2012) Bioanalysis , vol.4 , pp. 1287-1297
    • Rainville, P.D.1    Simeone, J.L.2    McCarthy, S.M.3    Smith, N.W.4    Cowan, D.5    Plumb, R.S.6
  • 34
    • 25144468977 scopus 로고    scopus 로고
    • All-in-one' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching
    • Wrona M., Mauriala T., Bateman K.P., Mortishire-Smith R.J., O'Connor D. All-in-one' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching. Rapid Commun. Mass Spectrom 2005, 19:2597-2602.
    • (2005) Rapid Commun. Mass Spectrom , vol.19 , pp. 2597-2602
    • Wrona, M.1    Mauriala, T.2    Bateman, K.P.3    Mortishire-Smith, R.J.4    O'Connor, D.5
  • 35
    • 33749512402 scopus 로고    scopus 로고
    • The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry
    • Plumb R.S., Johnson K.A., Rainville P., Shockcor J.P., Williams R., Granger J.H., et al. The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom 2006, 20:2800-2806.
    • (2006) Rapid Commun. Mass Spectrom , vol.20 , pp. 2800-2806
    • Plumb, R.S.1    Johnson, K.A.2    Rainville, P.3    Shockcor, J.P.4    Williams, R.5    Granger, J.H.6
  • 38
    • 33750259677 scopus 로고    scopus 로고
    • Generation of ultrahigh peak capacity LC separations via elevated temperatures and high linear mobile-phase velocities
    • Plumb R.S., Rainville P., Smith B.W., Johnson K.A., Castro-Perez J., Wilson I.D., et al. Generation of ultrahigh peak capacity LC separations via elevated temperatures and high linear mobile-phase velocities. Anal. Chem 2006, 78:7278-7283.
    • (2006) Anal. Chem , vol.78 , pp. 7278-7283
    • Plumb, R.S.1    Rainville, P.2    Smith, B.W.3    Johnson, K.A.4    Castro-Perez, J.5    Wilson, I.D.6
  • 39
    • 48749104900 scopus 로고    scopus 로고
    • High temperature-ultra performance liquid chromatography for biomarker structure elucidation
    • Gika H.G., Theodoridis G., Extance J., Edge A.M., Wilson I.D. High temperature-ultra performance liquid chromatography for biomarker structure elucidation. J. Chromatogr. B 2008, 871:279-287.
    • (2008) J. Chromatogr. B , vol.871 , pp. 279-287
    • Gika, H.G.1    Theodoridis, G.2    Extance, J.3    Edge, A.M.4    Wilson, I.D.5
  • 40
    • 36748999504 scopus 로고    scopus 로고
    • Thermal gradients for the control of elution in RP-LC: application to the separation of model drugs
    • Edge A.M., Wilson I.D., Shillingford S. Thermal gradients for the control of elution in RP-LC: application to the separation of model drugs. Chromatographia 2007, 66:831-836.
    • (2007) Chromatographia , vol.66 , pp. 831-836
    • Edge, A.M.1    Wilson, I.D.2    Shillingford, S.3
  • 41
    • 0037083636 scopus 로고    scopus 로고
    • Analysis of highly polar compounds of plant origin: combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry
    • Tolstikov V.V., Feihn O. Analysis of highly polar compounds of plant origin: combination of hydrophilic interaction chromatography and electrospray ion trap mass spectrometry. Anal. Biochem 2002, 301:298-307.
    • (2002) Anal. Biochem , vol.301 , pp. 298-307
    • Tolstikov, V.V.1    Feihn, O.2
  • 42
    • 28444461025 scopus 로고    scopus 로고
    • Metabolic fingerprinting of rat urine by LC/MS: Part 1. Analysis by hydrophilic interaction liquid chromatography hydrophilic Interaction Chromatography-mass spectrometry
    • Idborg H., Zamani L., Shuppe-Koistinen I., Jacobsson S.J. Metabolic fingerprinting of rat urine by LC/MS: Part 1. Analysis by hydrophilic interaction liquid chromatography hydrophilic Interaction Chromatography-mass spectrometry. J. Chromatogr. B 2005, 828:9-13.
    • (2005) J. Chromatogr. B , vol.828 , pp. 9-13
    • Idborg, H.1    Zamani, L.2    Shuppe-Koistinen, I.3    Jacobsson, S.J.4
  • 43
    • 77950811675 scopus 로고    scopus 로고
    • Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies
    • Spagou K., Tsoukali K., Nikolaos R., Gika H., Wilson I.D., Theodoridis G. Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies. J. Sep. Sci 2010, 33:716-727.
    • (2010) J. Sep. Sci , vol.33 , pp. 716-727
    • Spagou, K.1    Tsoukali, K.2    Nikolaos, R.3    Gika, H.4    Wilson, I.D.5    Theodoridis, G.6
  • 45
    • 84866338622 scopus 로고    scopus 로고
    • Quantitative profiling of polar primary metabolites using hydrophilic interaction ultrahigh performance liquid chromatographyn Trap Mass Spectrometry
    • Gika H.G., Theodoridis G., Vrhovsek U., Mattivi F. Quantitative profiling of polar primary metabolites using hydrophilic interaction ultrahigh performance liquid chromatographyn Trap Mass Spectrometry. J. Chromatogr. A 2012, 1259:121-127.
    • (2012) J. Chromatogr. A , vol.1259 , pp. 121-127
    • Gika, H.G.1    Theodoridis, G.2    Vrhovsek, U.3    Mattivi, F.4
  • 46
    • 45949087351 scopus 로고    scopus 로고
    • Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine
    • Gika H.G., Theodoridis G.A., Wilson I.D. Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine. J. Sep. Sci 2008, 31:1598-1608.
    • (2008) J. Sep. Sci , vol.31 , pp. 1598-1608
    • Gika, H.G.1    Theodoridis, G.A.2    Wilson, I.D.3
  • 47
    • 84863422028 scopus 로고    scopus 로고
    • Evaluation of coupling reversed phase, aqueous normal phase, and hydrophilic interaction liquid chromatography with Orbitrap mass spectrometry for metabolomic studies of human urine
    • Zhang T., Creek D.J., Barrett M.P., Blackburn G., Watson D.G. Evaluation of coupling reversed phase, aqueous normal phase, and hydrophilic interaction liquid chromatography with Orbitrap mass spectrometry for metabolomic studies of human urine. Anal. Chem 2012, 84:1994-2001.
    • (2012) Anal. Chem , vol.84 , pp. 1994-2001
    • Zhang, T.1    Creek, D.J.2    Barrett, M.P.3    Blackburn, G.4    Watson, D.G.5
  • 48
    • 84880531636 scopus 로고    scopus 로고
    • Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism
    • Ivanisevic J., Zhu Z.-J., Plate L., Tautenhahn R., Chen S., O'Brien P.J., et al. Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism. Anal. Chem 2013, 85:6876-6884.
    • (2013) Anal. Chem , vol.85 , pp. 6876-6884
    • Ivanisevic, J.1    Zhu, Z.-J.2    Plate, L.3    Tautenhahn, R.4    Chen, S.5    O'Brien, P.J.6
  • 49
    • 45949109943 scopus 로고    scopus 로고
    • Evaluation of hydrophilic interaction chromatography versus reversed-phase chromatography in a plant metabolomics perspective
    • T'kindt R., Storme M., Deforce D., Van Bocxlaer J. Evaluation of hydrophilic interaction chromatography versus reversed-phase chromatography in a plant metabolomics perspective. J. Sep. Sci 2008, 31:1609-1614.
    • (2008) J. Sep. Sci , vol.31 , pp. 1609-1614
    • T'kindt, R.1    Storme, M.2    Deforce, D.3    Van Bocxlaer, J.4
  • 50
    • 78650769334 scopus 로고    scopus 로고
    • HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies
    • Spagou K., Wilson I.D., Masson P., Theodoridis G., Raikos N., Coen M., et al. HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies. Anal. Chem 2011, 83:382-390.
    • (2011) Anal. Chem , vol.83 , pp. 382-390
    • Spagou, K.1    Wilson, I.D.2    Masson, P.3    Theodoridis, G.4    Raikos, N.5    Coen, M.6
  • 51
    • 35648970604 scopus 로고    scopus 로고
    • Quantification of sugars and sugar phosphates in Arabidopsis thaliana tissues using porous graphitic carbon liquid chromatography-electrospray ionization mass spectrometry
    • Antonio C., Larson T., Gilday A., Graham I., Bergstro¨m E., Thomas-Oates J. Quantification of sugars and sugar phosphates in Arabidopsis thaliana tissues using porous graphitic carbon liquid chromatography-electrospray ionization mass spectrometry. J. Chromatogr. A 2007, 1172:170-178.
    • (2007) J. Chromatogr. A , vol.1172 , pp. 170-178
    • Antonio, C.1    Larson, T.2    Gilday, A.3    Graham, I.4    Bergstro¨m, E.5    Thomas-Oates, J.6
  • 52
    • 78649708170 scopus 로고    scopus 로고
    • Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon
    • Pabst M., Grass J., Fischl R., Le´onard R., Jin C., Hinterko¨rner G., et al. Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon. Anal. Chem 2010, 82:9782-9788.
    • (2010) Anal. Chem , vol.82 , pp. 9782-9788
    • Pabst, M.1    Grass, J.2    Fischl, R.3    Le´onard, R.4    Jin, C.5    Hinterko¨rner, G.6
  • 53
    • 84901606587 scopus 로고    scopus 로고
    • Targeted profiling of polar intracellular metabolites using ion-pair-high performance liquid chromatography and -ultra high performance liquid chromatography coupled to tandem mass spectrometry: applications to serum, urine and tissue extracts
    • Michopoulos F., Whalley N., Theodoridis G., Wilson I.D., Dunkley T.P.J., Critchlow S.E. Targeted profiling of polar intracellular metabolites using ion-pair-high performance liquid chromatography and -ultra high performance liquid chromatography coupled to tandem mass spectrometry: applications to serum, urine and tissue extracts. J. Chromatogr. A 2014, 1349:60-68.
    • (2014) J. Chromatogr. A , vol.1349 , pp. 60-68
    • Michopoulos, F.1    Whalley, N.2    Theodoridis, G.3    Wilson, I.D.4    Dunkley, T.P.J.5    Critchlow, S.E.6
  • 54
    • 70149124386 scopus 로고    scopus 로고
    • Profiling of polar metabolites in biological extracts using diamond hydride-based aqueous normal phase chromatography
    • Callahan D.L., De Souza D., Bacic A., Roessner U. Profiling of polar metabolites in biological extracts using diamond hydride-based aqueous normal phase chromatography. J. Sep. Sci 2009, 32:2273-2280.
    • (2009) J. Sep. Sci , vol.32 , pp. 2273-2280
    • Callahan, D.L.1    De Souza, D.2    Bacic, A.3    Roessner, U.4
  • 55
    • 33748784390 scopus 로고    scopus 로고
    • Simultaneous quantitative analysis of metabolites using ion-pair liquid chromatography-electrospray ionization mass spectrometry
    • Coulier L., Bas R., Jespersen S., Verheij E., van der Werf M.J., Hankemeier T. Simultaneous quantitative analysis of metabolites using ion-pair liquid chromatography-electrospray ionization mass spectrometry. Anal. Chem 2006, 78:6573-6582.
    • (2006) Anal. Chem , vol.78 , pp. 6573-6582
    • Coulier, L.1    Bas, R.2    Jespersen, S.3    Verheij, E.4    van der Werf, M.J.5    Hankemeier, T.6
  • 57
    • 79955960918 scopus 로고    scopus 로고
    • Linking energy metabolism to dysfunctions in mitochondrial respiration - linking energy an in vitro approach
    • Balcke G.U., Kolle S.N., Kamp H., Bethan B., Looser R., Wagner S., et al. Linking energy metabolism to dysfunctions in mitochondrial respiration - linking energy an in vitro approach. Toxicol. Lett 2011, 203:200-209.
    • (2011) Toxicol. Lett , vol.203 , pp. 200-209
    • Balcke, G.U.1    Kolle, S.N.2    Kamp, H.3    Bethan, B.4    Looser, R.5    Wagner, S.6
  • 58
    • 77951072181 scopus 로고    scopus 로고
    • Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone Orbitrap mass spectrometer
    • Lu W., Clasquin M.F., Melamud E., Amador-Noguez D., Caudy A.A., Rabinowitz J.D. Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone Orbitrap mass spectrometer. Anal. Chem 2010, 82:3212-3221.
    • (2010) Anal. Chem , vol.82 , pp. 3212-3221
    • Lu, W.1    Clasquin, M.F.2    Melamud, E.3    Amador-Noguez, D.4    Caudy, A.A.5    Rabinowitz, J.D.6
  • 59
    • 77952985821 scopus 로고    scopus 로고
    • Ultrahigh performance liquid chromatography-tandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites
    • Buescher J.M., Moco S., Sauerand U., Zamboni N. Ultrahigh performance liquid chromatography-tandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites. Anal. Chem 2010, 82:4403-4412.
    • (2010) Anal. Chem , vol.82 , pp. 4403-4412
    • Buescher, J.M.1    Moco, S.2    Sauerand, U.3    Zamboni, N.4
  • 60
    • 78349300605 scopus 로고    scopus 로고
    • Selectivity issues in targeted metabolomics: separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography
    • Hinterwirth H., La¨mmerhofer M., Preinerstorfer B., Gargano A., Reischl R., Bicker W., et al. Selectivity issues in targeted metabolomics: separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography. J. Sep. Sci 2010, 33:3273-3282.
    • (2010) J. Sep. Sci , vol.33 , pp. 3273-3282
    • Hinterwirth, H.1    La¨mmerhofer, M.2    Preinerstorfer, B.3    Gargano, A.4    Reischl, R.5    Bicker, W.6
  • 61
    • 80054756992 scopus 로고    scopus 로고
    • Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry
    • Burgess K., Creek D., Dewsbury P., Cook K., Barrett M.P. Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry. Rapid Commun. Mass Spectrom 2011, 25:3447-3452.
    • (2011) Rapid Commun. Mass Spectrom , vol.25 , pp. 3447-3452
    • Burgess, K.1    Creek, D.2    Dewsbury, P.3    Cook, K.4    Barrett, M.P.5
  • 62
    • 1242270533 scopus 로고    scopus 로고
    • Differences in preparative loadability between the charged and uncharged forms of ionizable compounds
    • Neue U.D., Wheat T.E., Mazzeo J.R., Mazza C.B., Cavanaugh J.Y., Xia F., et al. Differences in preparative loadability between the charged and uncharged forms of ionizable compounds. J. Chromatogr. A 2004, 1030:123-134.
    • (2004) J. Chromatogr. A , vol.1030 , pp. 123-134
    • Neue, U.D.1    Wheat, T.E.2    Mazzeo, J.R.3    Mazza, C.B.4    Cavanaugh, J.Y.5    Xia, F.6
  • 64
    • 77954596543 scopus 로고    scopus 로고
    • Metabolite profiles from dried biofluid spots for metabonomic studies using UPLC combined with oaToF-MS
    • Michopoulos F., Theodoridis G., Smith C.J., Wilson I.D. Metabolite profiles from dried biofluid spots for metabonomic studies using UPLC combined with oaToF-MS. J. Proteome Res 2010, 9:3328-3334.
    • (2010) J. Proteome Res , vol.9 , pp. 3328-3334
    • Michopoulos, F.1    Theodoridis, G.2    Smith, C.J.3    Wilson, I.D.4
  • 65
    • 79955433057 scopus 로고    scopus 로고
    • Addressing the challenge of limited sample volumes in in vitro studies with capillary-scale microfluidic LC-MS/MS
    • Rainville P.D., Smith N.W., Wilson I.D., Nicholson J.K., Plumb R.S. Addressing the challenge of limited sample volumes in in vitro studies with capillary-scale microfluidic LC-MS/MS. Bioanalysis 2011, 3:873-882.
    • (2011) Bioanalysis , vol.3 , pp. 873-882
    • Rainville, P.D.1    Smith, N.W.2    Wilson, I.D.3    Nicholson, J.K.4    Plumb, R.S.5
  • 66
    • 61449243723 scopus 로고    scopus 로고
    • Quantitative profiling of polar cationic metabolites in human cerebrospinal fluid by reversed-phase nanoliquid chromatography-mass spectrometry
    • Myint K.T., Aoshima K., Tanaka S., Nakamura T., Oda Y. Quantitative profiling of polar cationic metabolites in human cerebrospinal fluid by reversed-phase nanoliquid chromatography-mass spectrometry. Anal. Chem 2009, 81:1121-1129.
    • (2009) Anal. Chem , vol.81 , pp. 1121-1129
    • Myint, K.T.1    Aoshima, K.2    Tanaka, S.3    Nakamura, T.4    Oda, Y.5
  • 67
    • 70349106852 scopus 로고    scopus 로고
    • Polar anionic metabolome analysis by nano-LC-MS with a metal chelating agent
    • Myint K.T., Uehara T., Aoshima K., Oda Y. Polar anionic metabolome analysis by nano-LC-MS with a metal chelating agent. Anal. Chem 2009, 81:7766-7772.
    • (2009) Anal. Chem , vol.81 , pp. 7766-7772
    • Myint, K.T.1    Uehara, T.2    Aoshima, K.3    Oda, Y.4
  • 68
    • 79952125407 scopus 로고    scopus 로고
    • Nanoscale ion-pair reversed-phase HPLC-MS for sensitive metabolome analysis
    • Kiefer P., Delmotte N., Vorholt J.A. Nanoscale ion-pair reversed-phase HPLC-MS for sensitive metabolome analysis. Anal. Chem 2011, 83:850-855.
    • (2011) Anal. Chem , vol.83 , pp. 850-855
    • Kiefer, P.1    Delmotte, N.2    Vorholt, J.A.3
  • 69
    • 84856771205 scopus 로고    scopus 로고
    • Application of supercritical fluid chromatography/mass spectrometry to lipid profiling of soybean
    • Lee W., Uchikata T., Matsubara A., Fukusaki E., Bamba T. Application of supercritical fluid chromatography/mass spectrometry to lipid profiling of soybean. J. Biosci. Bioeng 2012, 113:262-268.
    • (2012) J. Biosci. Bioeng , vol.113 , pp. 262-268
    • Lee, W.1    Uchikata, T.2    Matsubara, A.3    Fukusaki, E.4    Bamba, T.5
  • 70
    • 84863862470 scopus 로고    scopus 로고
    • Metabolic profiling of lipids by supercritical fluid chromatography/mass spectrometry
    • Bamba T., Lee J.W., Matsubara A., Fukusaki E. Metabolic profiling of lipids by supercritical fluid chromatography/mass spectrometry. J. Chromatogr. A 2012, 1250:212-219.
    • (2012) J. Chromatogr. A , vol.1250 , pp. 212-219
    • Bamba, T.1    Lee, J.W.2    Matsubara, A.3    Fukusaki, E.4
  • 71
    • 84904665455 scopus 로고    scopus 로고
    • Ultra high resolution SFC-MS as a high throughput platform for metabolic phenotyping: application to metabolic profiling of rat and dog bile
    • Jones M.D., Rainville P.D., Isaac G., Wilson I.D., Smith N.W., Plumb R.S. Ultra high resolution SFC-MS as a high throughput platform for metabolic phenotyping: application to metabolic profiling of rat and dog bile. J. Chromatogr. B 2014, 10.1016/j.jchromb.2014.04.017.
    • (2014) J. Chromatogr. B
    • Jones, M.D.1    Rainville, P.D.2    Isaac, G.3    Wilson, I.D.4    Smith, N.W.5    Plumb, R.S.6
  • 72
    • 84879459890 scopus 로고    scopus 로고
    • Simultaneous and rapid analysis of bile acids including conjugates by supercritical fluid chromatography coupled to tandem mass spectrometry
    • Taguchi K., Fukusaki E., Bamba T. Simultaneous and rapid analysis of bile acids including conjugates by supercritical fluid chromatography coupled to tandem mass spectrometry. J. Chromatogr. A 2013, 1299:103-109.
    • (2013) J. Chromatogr. A , vol.1299 , pp. 103-109
    • Taguchi, K.1    Fukusaki, E.2    Bamba, T.3


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