An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 871, Issue 2, 2008, Pages 357-361

  Harry, Emma L ^a   Weston, Daniel J ^b   Bristow, Anthony W T ^b   Wilson, Ian D ^b   Creaser, Colin S ^a  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Ion mobility mass spectrometry; Metabonomics; Reversed phase HPLC; Urinary metabolome

Indexed keywords

BODY FLUIDS; CHLORINE COMPOUNDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DATA ACQUISITION; DECISION SUPPORT SYSTEMS; ELECTRON BEAM LITHOGRAPHY; ELECTROSPRAY IONIZATION; INFORMATION MANAGEMENT; INJECTION (OIL WELLS); INSULATING MATERIALS; INTEGRATED CONTROL; ION CHROMATOGRAPHY; ION SOURCES; IONIZATION OF LIQUIDS; IONS; ISOMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; PHASE SEPARATION; SEARCH ENGINES; SEPARATION; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; THROUGHPUT; TUBES (COMPONENTS);

ANALYSIS TIME; ANALYTE; ANALYTES; CHARACTERISATION; DATA SETS; DIRECT INJECTION; DRIFT TIME; DRIFT TUBES; ELECTRO SPRAYING; GAS-PHASE; GRADIENT ELUTION; HIGH-THROUGHPUT ANALYSIS; ION MOBILITIES; ION MOBILITY-MASS SPECTROMETRY; ION SUPPRESSIONS; MASS SPECTRUM; METABONOMIC ANALYSIS; METABONOMICS; MS APPROACH; NESTED DATA; QUADRUPOLE/TIME-OF-FLIGHT; RAT URINE; REVERSED-PHASE; REVERSED-PHASE HPLC; SAMPLE PREPARATIONS; SPECTRAL QUALITY; URINARY METABOLOME;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ARTICLE; ELECTROSPRAY; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; ION MOBILITY SPECTROMETRY; MALE; METABOLOMICS; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSED PHASE LIQUID CHROMATOGRAPHY; STATISTICAL SIGNIFICANCE; URINALYSIS;

ANIMALS; CHROMATOGRAPHY, LIQUID; COMPUTATIONAL BIOLOGY; MALE; MASS SPECTROMETRY; METABOLISM; RATS; RATS, WISTAR; URINE;

CHLORINE COMPOUNDS; CHROMATOGRAPHY; DATA PROCESSING; ELECTRON BEAMS; INSULATION; IONS; LIQUID CHROMATOGRAPHY; LITHOGRAPHY; MASS SPECTROMETERS; SEPARATION;

RATTUS;

EID: 48949106229     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.04.043     Document Type: Article

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