-
1
-
-
77956294987
-
Inhibition of hypoxia-inducible factor-1 alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents
-
J.J. Lou, Y.L. Chua, E.H. Chew, J. Gao, M. Bushell, T. Hagen, Inhibition of hypoxia-inducible factor-1 alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents. PLoS One 5, e10522 (2010)
-
(2010)
PLoS One
, vol.5
-
-
Lou, J.J.1
Chua, Y.L.2
Chew, E.H.3
Gao, J.4
Bushell, M.5
Hagen, T.6
-
2
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
A.J. Majmundar, W.J. Wong, M.C. Simon, Hypoxia-inducible factors and the response to hypoxic stress. Mol. Cell 40, 294-309 (2010)
-
(2010)
Mol. Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
3
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
G.L. Semenza, Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3, 721-732 (2003)
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
4
-
-
54549113030
-
The von Hippel-Lindau tumour suppressor protein: O2sensing and cancer
-
W.G. Kaelin Jr., The von Hippel-Lindau tumour suppressor protein: O2sensing and cancer. Nat. Rev. Cancer 8, 865-873 (2008)
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 865-873
-
-
Kaelin Jr., W.G.1
-
5
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
-
N. Masson, C. Willam, P.H. Maxwell, C.W. Pugh, P.J. Ratcliffe, Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J. 20, 5197-5206 (2001)
-
(2001)
EMBO J.
, vol.20
, pp. 5197-5206
-
-
Masson, N.1
Willam, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
6
-
-
11244315697
-
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
-
D.J. Manalo, A. Rowan, T. Lavoie, L. Natarajan, B.D. Kelly, S.Q. Ye, J.G. Garcia, G.L. Semenza, Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 105, 659-669 (2005)
-
(2005)
Blood
, vol.105
, pp. 659-669
-
-
Manalo, D.J.1
Rowan, A.2
Lavoie, T.3
Natarajan, L.4
Kelly, B.D.5
Ye, S.Q.6
Garcia, J.G.7
Semenza, G.L.8
-
7
-
-
79961069521
-
Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo
-
C.D. Young, A.S. Lewis, M.C. Rudolph, M.D. Ruehle, M.R. Jackman, U.J. Yun, O. Ilkun, R. Pereira, E.D. Abel, S.M. Anderson, Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo. PLoS One 6, e23205 (2011)
-
(2011)
PLoS One
, vol.6
-
-
Young, C.D.1
Lewis, A.S.2
Rudolph, M.C.3
Ruehle, M.D.4
Jackman, M.R.5
Yun, U.J.6
Ilkun, O.7
Pereira, R.8
Abel, E.D.9
Anderson, S.M.10
-
8
-
-
39449117751
-
Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines
-
N. Shaida, R. Launchbury, J.L. Boddy, C. Jones, L. Campo, H. Turley, S. Kanga, A.H. Banham, P.R. Malone, A.L. Harris, S.B. Fox, Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines. Prostate 68, 336-343 (2008)
-
(2008)
Prostate
, vol.68
, pp. 336-343
-
-
Shaida, N.1
Launchbury, R.2
Boddy, J.L.3
Jones, C.4
Campo, L.5
Turley, H.6
Kanga, S.7
Banham, A.H.8
Malone, P.R.9
Harris, A.L.10
Fox, S.B.11
-
9
-
-
23844517036
-
Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer
-
H. Bando, T. Atsumi, T. Nishio, H. Niwa, S. Mishima, C. Shimizu, N. Yoshioka, R. Bucala, T. Koike, Phosphorylation of the 6-phosphofructo-2-kinase/ fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer. Clin. Cancer Res. 11, 5784-5792 (2005)
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 5784-5792
-
-
Bando, H.1
Atsumi, T.2
Nishio, T.3
Niwa, H.4
Mishima, S.5
Shimizu, C.6
Yoshioka, N.7
Bucala, R.8
Koike, T.9
-
10
-
-
84861306930
-
Miconazole, a pharmacological barrier to skin fungal infections
-
G.E. Piérard, T. Hermanns-Lê, P. Delvenne, C. Piérard-Franchimont, Miconazole, a pharmacological barrier to skin fungal infections. Expert. Opin. Pharmacother. 13, 1187-1194 (2012)
-
(2012)
Expert. Opin. Pharmacother.
, vol.13
, pp. 1187-1194
-
-
Piérard, G.E.1
Hermanns-Lê, T.2
Delvenne, P.3
Piérard- Franchimont, C.4
-
11
-
-
13844255564
-
Effect of miconazole on intracellular Ca2+ levels and proliferation in human osteosarcoma cells
-
H.T. Chang, W.C. Chen, J.S. Chen, Y.C. Lu, S.S. Hsu, J.L. Wang, H.H. Cheng, J.S. Cheng, B.P. Jiann, A.J. Chiang, J.K. Huang, C.R. Jan, Effect of miconazole on intracellular Ca2+ levels and proliferation in human osteosarcoma cells. Life Sci. 76, 2091-2101 (2005)
-
(2005)
Life Sci.
, vol.76
, pp. 2091-2101
-
-
Chang, H.T.1
Chen, W.C.2
Chen, J.S.3
Lu, Y.C.4
Hsu, S.S.5
Wang, J.L.6
Cheng, H.H.7
Cheng, J.S.8
Jiann, B.P.9
Chiang, A.J.10
Huang, J.K.11
Jan, C.R.12
-
12
-
-
48749116836
-
Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme
-
D. Zagorac, D. Jakovcevic, D. Gebremedhin, D.R. Harder, Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme. J. Cereb. Blood Flow Metab. 28, 1431-1439 (2008)
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, pp. 1431-1439
-
-
Zagorac, D.1
Jakovcevic, D.2
Gebremedhin, D.3
Harder, D.R.4
-
13
-
-
0036534524
-
Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest
-
C.H. Wu, J.H. Jeng, Y.J. Wang, C.J. Tseng, Y.C. Liang, C.H. Chen, H.M. Lee, J.K. Lin, C.H. Lin, S.Y. Lin, C.P. Li, Y.S. Ho, Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest. Toxicol. Appl. Pharmacol. 180, 22-35 (2002)
-
(2002)
Toxicol. Appl. Pharmacol.
, vol.180
, pp. 22-35
-
-
Wu, C.H.1
Jeng, J.H.2
Wang, Y.J.3
Tseng, C.J.4
Liang, Y.C.5
Chen, C.H.6
Lee, H.M.7
Lin, J.K.8
Lin, C.H.9
Lin, S.Y.10
Li, C.P.11
Ho, Y.S.12
-
14
-
-
27144458505
-
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
-
M. Bi, C. Naczki, M. Koritzinsky, D. Fels, J. Blais, N. Hu, H. Harding, I. Novoa, M. Varia, J. Raleigh, D. Scheuner, R.J. Kaufman, J. Bell, D. Ron, B.G. Wouters, C. Koumenis, ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J. 24, 3470-3481 (2005)
-
(2005)
EMBO J.
, vol.24
, pp. 3470-3481
-
-
Bi, M.1
Naczki, C.2
Koritzinsky, M.3
Fels, D.4
Blais, J.5
Hu, N.6
Harding, H.7
Novoa, I.8
Varia, M.9
Raleigh, J.10
Scheuner, D.11
Kaufman, R.J.12
Bell, J.13
Ron, D.14
Wouters, B.G.15
Koumenis, C.16
-
15
-
-
79951850723
-
Pentamidine reduces expression of hypoxia-inducible factor-1α in DU145 and MDA-MB-231 cancer cells
-
H.J. Jung, S.I. Suh, M.H. Suh, W.K. Baek, J.W. Park, Pentamidine reduces expression of hypoxia-inducible factor-1α in DU145 and MDA-MB-231 cancer cells. Cancer Lett. 303, 39-46 (2011)
-
(2011)
Cancer Lett.
, vol.303
, pp. 39-46
-
-
Jung, H.J.1
Suh, S.I.2
Suh, M.H.3
Baek, W.K.4
Park, J.W.5
-
16
-
-
0036682284
-
Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway
-
A. Rapisarda, B. Uranchimeg, D.A. Scudiero, M. Selby, E.A. Sausville, R.H. Shoemaker, G. Melillo, Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res. 62, 4316-4324 (2002)
-
(2002)
Cancer Res.
, vol.62
, pp. 4316-4324
-
-
Rapisarda, A.1
Uranchimeg, B.2
Scudiero, D.A.3
Selby, M.4
Sausville, E.A.5
Shoemaker, R.H.6
Melillo, G.7
-
17
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
-
K.L. Talks, H. Turley, K.C. Gatter, P.H. Maxwell, C.W. Pugh, P.J. Ratcliffe, A.L. Harris, The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol. 157, 411-421 (2000)
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliffe, P.J.6
Harris, A.L.7
-
18
-
-
80053208251
-
PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells
-
J. Du, R. Xu, Z. Hu, Y. Tian, Y. Zhu, L. Gu, L. Zhou, PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells. PLoS One 6, e25213 (2011)
-
(2011)
PLoS One
, vol.6
-
-
Du, J.1
Xu, R.2
Hu, Z.3
Tian, Y.4
Zhu, Y.5
Gu, L.6
Zhou, L.7
-
19
-
-
84879237688
-
HIF-1α and NOTCH signaling in ductal and lobular carcinomas of the breast
-
C. Ercan, J.F. Vermeulen, L. Hoefnagel, P. Bult, P. van der Groep, E. van der Wall, P.J. van Diest, HIF-1α and NOTCH signaling in ductal and lobular carcinomas of the breast. Cell. Oncol. 35, 435-442 (2012)
-
(2012)
Cell. Oncol.
, vol.35
, pp. 435-442
-
-
Ercan, C.1
Vermeulen, J.F.2
Hoefnagel, L.3
Bult, P.4
Van Der Groep, P.5
Van Der Wall, E.6
Van Diest, P.J.7
-
20
-
-
54249164450
-
HIF-1 regulation: Not so easy come, easy go
-
M. Yee Koh, T.R. Spivak-Kroizman, G. Powis, HIF-1 regulation: not so easy come, easy go. Trends Biochem. Sci. 33, 526-534 (2008)
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 526-534
-
-
Yee Koh, M.1
Spivak-Kroizman, T.R.2
Powis, G.3
-
21
-
-
67650480092
-
mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome
-
D.B. Shackelford, D.S. Vasquez, J. Corbeil, S. Wu, M. Leblanc, C.L. Wu, D.R. Vera, R.J. Shaw, mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome. Proc. Natl. Acad. Sci. U. S. A. 106, 11137-11142 (2009)
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 11137-11142
-
-
Shackelford, D.B.1
Vasquez, D.S.2
Corbeil, J.3
Wu, S.4
Leblanc, M.5
Wu, C.L.6
Vera, D.R.7
Shaw, R.J.8
-
22
-
-
0345732640
-
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
-
D.C. Fingar, C.J. Richardson, A.R. Tee, L. Cheatham, C. Tsou, J. Blenis, mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol. Cell. Biol. 24, 200-216 (2004)
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 200-216
-
-
Fingar, D.C.1
Richardson, C.J.2
Tee, A.R.3
Cheatham, L.4
Tsou, C.5
Blenis, J.6
-
23
-
-
0034705239
-
Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes
-
F.H. Pham, P.H. Sugden, A. Clerk, Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes. Circ. Res. 86, 1252-1258 (2000)
-
(2000)
Circ. Res.
, vol.86
, pp. 1252-1258
-
-
Pham, F.H.1
Sugden, P.H.2
Clerk, A.3
-
24
-
-
32544446451
-
Coping with stress: EIF2 kinases and translational control
-
R.C. Wek, H.Y. Jiang, T.G. Anthony, Coping with stress: eIF2 kinases and translational control. Biochem. Soc. Trans. 34, 7-11 (2006)
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 7-11
-
-
Wek, R.C.1
Jiang, H.Y.2
Anthony, T.G.3
-
25
-
-
0023610798
-
Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cytochromes P-450
-
A.D. Rodrigues, D.F. Lewis, C. Ioannides, D.V. Parke, Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cytochromes P-450. Xenobiotica 17, 1315-1327 (1987)
-
(1987)
Xenobiotica
, vol.17
, pp. 1315-1327
-
-
Rodrigues, A.D.1
Lewis, D.F.2
Ioannides, C.3
Parke, D.V.4
-
26
-
-
0018852488
-
In vitro activities of miconazole, miconazole nitrate, and ketoconazole alone and combined with rifampin against Candida spp. And Torulopsis glabrata recovered from cancer patients
-
M.R. Moody, V.M. Young, M.J. Morris, S.C. Schimpff, In vitro activities of miconazole, miconazole nitrate, and ketoconazole alone and combined with rifampin against Candida spp. and Torulopsis glabrata recovered from cancer patients. Antimicrob. Agents Chemother. 17, 871-875 (1980)
-
(1980)
Antimicrob. Agents Chemother.
, vol.17
, pp. 871-875
-
-
Moody, M.R.1
Young, V.M.2
Morris, M.J.3
Schimpff, S.C.4
-
27
-
-
0018591091
-
Miconazole therapy for treatment of fungal infections in cancer patients
-
W.M. Jordan, G.P. Bodey, V. Rodriguez, S.J. Ketchel, J. Henney, Miconazole therapy for treatment of fungal infections in cancer patients. Antimicrob. Agents Chemother. 16, 792-797 (1979)
-
(1979)
Antimicrob. Agents Chemother.
, vol.16
, pp. 792-797
-
-
Jordan, W.M.1
Bodey, G.P.2
Rodriguez, V.3
Ketchel, S.J.4
Henney, J.5
-
28
-
-
0020656680
-
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients
-
F. Meunier-Carpentier, M. Cruciani, J. Klastersky, Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. Eur. J. Cancer Clin. Oncol. 19, 43-48 (1983)
-
(1983)
Eur. J. Cancer Clin. Oncol.
, vol.19
, pp. 43-48
-
-
Meunier-Carpentier, F.1
Cruciani, M.2
Klastersky, J.3
-
29
-
-
0030745630
-
Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancermodel
-
R.A. Lubet, V.E. Steele, I. Eto, M.M. Juliana, G.J. Kelloff, C.J. Grubbs, Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancermodel. Int. J. Cancer 72, 95-101 (1997)
-
(1997)
Int. J. Cancer
, vol.72
, pp. 95-101
-
-
Lubet, R.A.1
Steele, V.E.2
Eto, I.3
Juliana, M.M.4
Kelloff, G.J.5
Grubbs, C.J.6
-
30
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and theirmetastases
-
H. Zhong, A.M. De Marzo, E. Laughner, M. Lim, D.A. Hilton, D. Zagzag, P. Buechler, W.B. Isaacs, G.L. Semenza, J.W. Simons, Overexpression of hypoxia-inducible factor 1alpha in common human cancers and theirmetastases. Cancer Res. 59, 5830-5835 (1999)
-
(1999)
Cancer Res.
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
31
-
-
0842333201
-
Prognostic significance of HIF-1 alpha overexpression in human pancreatic cancer
-
T. Shibaji, M. Nagao, N. Ikeda, H. Kanehiro, M. Hisanaga, S. Ko, A. Fukumoto, Y. Nakajima, Prognostic significance of HIF-1 alpha overexpression in human pancreatic cancer. Anticancer Res. 23, 4721-4727 (2003)
-
(2003)
Anticancer Res.
, vol.23
, pp. 4721-4727
-
-
Shibaji, T.1
Nagao, M.2
Ikeda, N.3
Kanehiro, H.4
Hisanaga, M.5
Ko, S.6
Fukumoto, A.7
Nakajima, Y.8
-
32
-
-
0037500967
-
Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer
-
B. Bachtiary, M. Schindl, R. Potter, B. Dreier, T.H. Knocke, J.A. Hainfellner, R. Horvat, P. Birner, Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer. Clin. Cancer Res. 9, 2234-2240 (2003)
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2234-2240
-
-
Bachtiary, B.1
Schindl, M.2
Potter, R.3
Dreier, B.4
Knocke, T.H.5
Hainfellner, J.A.6
Horvat, R.7
Birner, P.8
-
33
-
-
0037443587
-
Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma
-
R. Bos, P. van der Groep, A.E. Greijer, A. Shvarts, S.Meijer, H.M. Pinedo, G.L. Semenza, P.J. van Diest, E. van der Wall, Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma. Cancer 97, 1573-1581 (2003)
-
(2003)
Cancer
, vol.97
, pp. 1573-1581
-
-
Bos, R.1
Van Der Groep, P.2
Greijer, A.E.3
Shvarts, A.4
Meijer, S.5
Pinedo, H.M.6
Semenza, G.L.7
Van Diest, P.J.8
Van Der Wall, E.9
-
34
-
-
4444311880
-
Hypoxia inducible factor-1alpha as a cancer drug target
-
G. Powis, L. Kirkpatrick, Hypoxia inducible factor-1alpha as a cancer drug target. Mol. Cancer Ther. 3, 647-654 (2004)
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 647-654
-
-
Powis, G.1
Kirkpatrick, L.2
-
35
-
-
27544491447
-
Angiogenic and antiangiogenic gene therapy
-
M. Malecki, P. Kolsut, R. Proczka, Angiogenic and antiangiogenic gene therapy. Gene Ther. 12(Suppl 1), S159-S169 (2005)
-
(2005)
Gene Ther.
, vol.12
, Issue.SUPPL. 1
-
-
Malecki, M.1
Kolsut, P.2
Proczka, R.3
-
36
-
-
33747810445
-
Angiogenesis in cancer
-
N. Nishida, H. Yano, T. Nishida, T. Kamura, M. Kojiro, Angiogenesis in cancer. Vasc. Health Risk Manag. 2, 213-219 (2006)
-
(2006)
Vasc. Health Risk Manag.
, vol.2
, pp. 213-219
-
-
Nishida, N.1
Yano, H.2
Nishida, T.3
Kamura, T.4
Kojiro, M.5
-
37
-
-
0037316605
-
Matrix metalloproteinases, angiogenesis, and cancer
-
J.E. Rundhaug, Matrix metalloproteinases, angiogenesis, and cancer. Clin. Cancer Res. 9, 551-554 (2003)
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 551-554
-
-
Rundhaug, J.E.1
-
38
-
-
0037230201
-
Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells
-
M. Medhora, J. Daniels, K. Mundey, B. Fisslthaler, R. Busse, E.R. Jacobs, D.R. Harder, Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 284, H215-H224 (2003)
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.284
-
-
Medhora, M.1
Daniels, J.2
Mundey, K.3
Fisslthaler, B.4
Busse, R.5
Jacobs, E.R.6
Harder, D.R.7
-
39
-
-
0036901546
-
Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid
-
C. Zhang, D.R. Harder, Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid. Stroke 33, 2957-2964 (2002)
-
(2002)
Stroke
, vol.33
, pp. 2957-2964
-
-
Zhang, C.1
Harder, D.R.2
-
40
-
-
0034109792
-
Cerebral microvascular endothelial cell tube formation: Role of astrocytic epoxyeicosatrienoic acid release
-
D.H.Munzenmaier, D.R. Harder, Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release. Am. J. Physiol.Heart Circ. Physiol. 278, H1163-H1167 (2000)
-
(2000)
Am. J. Physiol.Heart Circ. Physiol.
, vol.278
-
-
Munzenmaier, D.H.1
Harder, D.R.2
-
41
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
R.J. Shaw, L.C. Cantley, Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441, 424-430 (2006)
-
(2006)
Nature
, vol.441
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
42
-
-
35348954836
-
UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway
-
A. Rapisarda, G. Melillo, UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway. Oncogene 26, 6875-6884 (2007)
-
(2007)
Oncogene
, vol.26
, pp. 6875-6884
-
-
Rapisarda, A.1
Melillo, G.2
-
43
-
-
33646550165
-
Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells
-
E. Connolly, S. Braunstein, S. Formenti, R.J. Schneider, Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. Mol. Cell. Biol. 26, 3955-3965 (2006)
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3955-3965
-
-
Connolly, E.1
Braunstein, S.2
Formenti, S.3
Schneider, R.J.4
-
44
-
-
77955272978
-
P70S6K 1 regulation of angiogenesis through VEGF and HIF-1alpha expression
-
C.X. Bian, Z. Shi, Q. Meng, Y. Jiang, L.Z. Liu, B.H. Jiang, P70S6K 1 regulation of angiogenesis through VEGF and HIF-1alpha expression. Biochem. Biophys. Res. Commun. 398, 395-399 (2010)
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.398
, pp. 395-399
-
-
Bian, C.X.1
Shi, Z.2
Meng, Q.3
Jiang, Y.4
Liu, L.Z.5
Jiang, B.H.6
-
45
-
-
34347220473
-
Defining the role of mTOR in cancer
-
D.A. Guertin, D.M. Sabatini, Defining the role of mTOR in cancer. Cancer Cell 12, 9-22 (2007)
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
46
-
-
58649097037
-
Mutual regulation of hypoxia-inducible factor and mammalian target of rapamycin as a function of oxygen availability
-
K.X. Knaup, K. Jozefowski, R. Schmidt, W.M. Bernhardt, A. Weidemann, J.S. Juergensen, C. Warnecke, K.U. Eckardt, M.S. Wiesener, Mutual regulation of hypoxia-inducible factor and mammalian target of rapamycin as a function of oxygen availability.Mol. Cancer Res. 7, 88-98 (2009)
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 88-98
-
-
Knaup, K.X.1
Jozefowski, K.2
Schmidt, R.3
Bernhardt, W.M.4
Weidemann, A.5
Juergensen, J.S.6
Warnecke, C.7
Eckardt, K.U.8
Wiesener, M.S.9
-
47
-
-
62449203027
-
Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression
-
K. Zhu, W. Chan, J. Heymach, M. Wilkinson, D.J. McConkey, Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression. Cancer Res. 69, 1836-1843 (2009)
-
(2009)
Cancer Res.
, vol.69
, pp. 1836-1843
-
-
Zhu, K.1
Chan, W.2
Heymach, J.3
Wilkinson, M.4
McConkey, D.J.5
-
48
-
-
0036837864
-
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
-
C. Koumenis, C. Naczki, M. Koritzinsky, S. Rastani, A. Diehl, N. Sonenberg, A. Koromilas, B.G. Wouters, Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol. Cell. Biol. 22, 7405-7416 (2002)
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7405-7416
-
-
Koumenis, C.1
Naczki, C.2
Koritzinsky, M.3
Rastani, S.4
Diehl, A.5
Sonenberg, N.6
Koromilas, A.7
Wouters, B.G.8
|