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Volumn 37, Issue 4, 2014, Pages 269-279

Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway

Author keywords

eIF2 ; HIF 1; Miconazole; mTOR; VEGF

Indexed keywords

ANGIOGENIC FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INITIATION FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; MICONAZOLE; VASCULOTROPIN; INITIATION FACTOR 2; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; VASCULOTROPIN A;

EID: 84906934594     PISSN: 22113428     EISSN: 22113436     Source Type: Journal    
DOI: 10.1007/s13402-014-0182-8     Document Type: Article
Times cited : (16)

References (48)
  • 1
    • 77956294987 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor-1 alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents
    • J.J. Lou, Y.L. Chua, E.H. Chew, J. Gao, M. Bushell, T. Hagen, Inhibition of hypoxia-inducible factor-1 alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents. PLoS One 5, e10522 (2010)
    • (2010) PLoS One , vol.5
    • Lou, J.J.1    Chua, Y.L.2    Chew, E.H.3    Gao, J.4    Bushell, M.5    Hagen, T.6
  • 2
    • 78649364332 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and the response to hypoxic stress
    • A.J. Majmundar, W.J. Wong, M.C. Simon, Hypoxia-inducible factors and the response to hypoxic stress. Mol. Cell 40, 294-309 (2010)
    • (2010) Mol. Cell , vol.40 , pp. 294-309
    • Majmundar, A.J.1    Wong, W.J.2    Simon, M.C.3
  • 3
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • G.L. Semenza, Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3, 721-732 (2003)
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 4
    • 54549113030 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumour suppressor protein: O2sensing and cancer
    • W.G. Kaelin Jr., The von Hippel-Lindau tumour suppressor protein: O2sensing and cancer. Nat. Rev. Cancer 8, 865-873 (2008)
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 865-873
    • Kaelin Jr., W.G.1
  • 5
    • 0035903468 scopus 로고    scopus 로고
    • Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
    • N. Masson, C. Willam, P.H. Maxwell, C.W. Pugh, P.J. Ratcliffe, Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J. 20, 5197-5206 (2001)
    • (2001) EMBO J. , vol.20 , pp. 5197-5206
    • Masson, N.1    Willam, C.2    Maxwell, P.H.3    Pugh, C.W.4    Ratcliffe, P.J.5
  • 8
    • 39449117751 scopus 로고    scopus 로고
    • Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines
    • N. Shaida, R. Launchbury, J.L. Boddy, C. Jones, L. Campo, H. Turley, S. Kanga, A.H. Banham, P.R. Malone, A.L. Harris, S.B. Fox, Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines. Prostate 68, 336-343 (2008)
    • (2008) Prostate , vol.68 , pp. 336-343
    • Shaida, N.1    Launchbury, R.2    Boddy, J.L.3    Jones, C.4    Campo, L.5    Turley, H.6    Kanga, S.7    Banham, A.H.8    Malone, P.R.9    Harris, A.L.10    Fox, S.B.11
  • 9
    • 23844517036 scopus 로고    scopus 로고
    • Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer
    • H. Bando, T. Atsumi, T. Nishio, H. Niwa, S. Mishima, C. Shimizu, N. Yoshioka, R. Bucala, T. Koike, Phosphorylation of the 6-phosphofructo-2-kinase/ fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer. Clin. Cancer Res. 11, 5784-5792 (2005)
    • (2005) Clin. Cancer Res. , vol.11 , pp. 5784-5792
    • Bando, H.1    Atsumi, T.2    Nishio, T.3    Niwa, H.4    Mishima, S.5    Shimizu, C.6    Yoshioka, N.7    Bucala, R.8    Koike, T.9
  • 12
    • 48749116836 scopus 로고    scopus 로고
    • Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme
    • D. Zagorac, D. Jakovcevic, D. Gebremedhin, D.R. Harder, Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme. J. Cereb. Blood Flow Metab. 28, 1431-1439 (2008)
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1431-1439
    • Zagorac, D.1    Jakovcevic, D.2    Gebremedhin, D.3    Harder, D.R.4
  • 15
    • 79951850723 scopus 로고    scopus 로고
    • Pentamidine reduces expression of hypoxia-inducible factor-1α in DU145 and MDA-MB-231 cancer cells
    • H.J. Jung, S.I. Suh, M.H. Suh, W.K. Baek, J.W. Park, Pentamidine reduces expression of hypoxia-inducible factor-1α in DU145 and MDA-MB-231 cancer cells. Cancer Lett. 303, 39-46 (2011)
    • (2011) Cancer Lett. , vol.303 , pp. 39-46
    • Jung, H.J.1    Suh, S.I.2    Suh, M.H.3    Baek, W.K.4    Park, J.W.5
  • 17
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
    • K.L. Talks, H. Turley, K.C. Gatter, P.H. Maxwell, C.W. Pugh, P.J. Ratcliffe, A.L. Harris, The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol. 157, 411-421 (2000)
    • (2000) Am. J. Pathol. , vol.157 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6    Harris, A.L.7
  • 18
    • 80053208251 scopus 로고    scopus 로고
    • PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells
    • J. Du, R. Xu, Z. Hu, Y. Tian, Y. Zhu, L. Gu, L. Zhou, PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells. PLoS One 6, e25213 (2011)
    • (2011) PLoS One , vol.6
    • Du, J.1    Xu, R.2    Hu, Z.3    Tian, Y.4    Zhu, Y.5    Gu, L.6    Zhou, L.7
  • 22
    • 0345732640 scopus 로고    scopus 로고
    • mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
    • D.C. Fingar, C.J. Richardson, A.R. Tee, L. Cheatham, C. Tsou, J. Blenis, mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol. Cell. Biol. 24, 200-216 (2004)
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 200-216
    • Fingar, D.C.1    Richardson, C.J.2    Tee, A.R.3    Cheatham, L.4    Tsou, C.5    Blenis, J.6
  • 23
    • 0034705239 scopus 로고    scopus 로고
    • Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes
    • F.H. Pham, P.H. Sugden, A. Clerk, Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes. Circ. Res. 86, 1252-1258 (2000)
    • (2000) Circ. Res. , vol.86 , pp. 1252-1258
    • Pham, F.H.1    Sugden, P.H.2    Clerk, A.3
  • 24
    • 32544446451 scopus 로고    scopus 로고
    • Coping with stress: EIF2 kinases and translational control
    • R.C. Wek, H.Y. Jiang, T.G. Anthony, Coping with stress: eIF2 kinases and translational control. Biochem. Soc. Trans. 34, 7-11 (2006)
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 7-11
    • Wek, R.C.1    Jiang, H.Y.2    Anthony, T.G.3
  • 25
    • 0023610798 scopus 로고
    • Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cytochromes P-450
    • A.D. Rodrigues, D.F. Lewis, C. Ioannides, D.V. Parke, Spectral and kinetic studies of the interaction of imidazole anti-fungal agents with microsomal cytochromes P-450. Xenobiotica 17, 1315-1327 (1987)
    • (1987) Xenobiotica , vol.17 , pp. 1315-1327
    • Rodrigues, A.D.1    Lewis, D.F.2    Ioannides, C.3    Parke, D.V.4
  • 26
    • 0018852488 scopus 로고
    • In vitro activities of miconazole, miconazole nitrate, and ketoconazole alone and combined with rifampin against Candida spp. And Torulopsis glabrata recovered from cancer patients
    • M.R. Moody, V.M. Young, M.J. Morris, S.C. Schimpff, In vitro activities of miconazole, miconazole nitrate, and ketoconazole alone and combined with rifampin against Candida spp. and Torulopsis glabrata recovered from cancer patients. Antimicrob. Agents Chemother. 17, 871-875 (1980)
    • (1980) Antimicrob. Agents Chemother. , vol.17 , pp. 871-875
    • Moody, M.R.1    Young, V.M.2    Morris, M.J.3    Schimpff, S.C.4
  • 28
    • 0020656680 scopus 로고
    • Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients
    • F. Meunier-Carpentier, M. Cruciani, J. Klastersky, Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. Eur. J. Cancer Clin. Oncol. 19, 43-48 (1983)
    • (1983) Eur. J. Cancer Clin. Oncol. , vol.19 , pp. 43-48
    • Meunier-Carpentier, F.1    Cruciani, M.2    Klastersky, J.3
  • 29
    • 0030745630 scopus 로고    scopus 로고
    • Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancermodel
    • R.A. Lubet, V.E. Steele, I. Eto, M.M. Juliana, G.J. Kelloff, C.J. Grubbs, Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancermodel. Int. J. Cancer 72, 95-101 (1997)
    • (1997) Int. J. Cancer , vol.72 , pp. 95-101
    • Lubet, R.A.1    Steele, V.E.2    Eto, I.3    Juliana, M.M.4    Kelloff, G.J.5    Grubbs, C.J.6
  • 32
    • 0037500967 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer
    • B. Bachtiary, M. Schindl, R. Potter, B. Dreier, T.H. Knocke, J.A. Hainfellner, R. Horvat, P. Birner, Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer. Clin. Cancer Res. 9, 2234-2240 (2003)
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2234-2240
    • Bachtiary, B.1    Schindl, M.2    Potter, R.3    Dreier, B.4    Knocke, T.H.5    Hainfellner, J.A.6    Horvat, R.7    Birner, P.8
  • 34
    • 4444311880 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha as a cancer drug target
    • G. Powis, L. Kirkpatrick, Hypoxia inducible factor-1alpha as a cancer drug target. Mol. Cancer Ther. 3, 647-654 (2004)
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 647-654
    • Powis, G.1    Kirkpatrick, L.2
  • 35
    • 27544491447 scopus 로고    scopus 로고
    • Angiogenic and antiangiogenic gene therapy
    • M. Malecki, P. Kolsut, R. Proczka, Angiogenic and antiangiogenic gene therapy. Gene Ther. 12(Suppl 1), S159-S169 (2005)
    • (2005) Gene Ther. , vol.12 , Issue.SUPPL. 1
    • Malecki, M.1    Kolsut, P.2    Proczka, R.3
  • 37
    • 0037316605 scopus 로고    scopus 로고
    • Matrix metalloproteinases, angiogenesis, and cancer
    • J.E. Rundhaug, Matrix metalloproteinases, angiogenesis, and cancer. Clin. Cancer Res. 9, 551-554 (2003)
    • (2003) Clin. Cancer Res. , vol.9 , pp. 551-554
    • Rundhaug, J.E.1
  • 39
    • 0036901546 scopus 로고    scopus 로고
    • Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid
    • C. Zhang, D.R. Harder, Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic acid. Stroke 33, 2957-2964 (2002)
    • (2002) Stroke , vol.33 , pp. 2957-2964
    • Zhang, C.1    Harder, D.R.2
  • 40
    • 0034109792 scopus 로고    scopus 로고
    • Cerebral microvascular endothelial cell tube formation: Role of astrocytic epoxyeicosatrienoic acid release
    • D.H.Munzenmaier, D.R. Harder, Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release. Am. J. Physiol.Heart Circ. Physiol. 278, H1163-H1167 (2000)
    • (2000) Am. J. Physiol.Heart Circ. Physiol. , vol.278
    • Munzenmaier, D.H.1    Harder, D.R.2
  • 41
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • R.J. Shaw, L.C. Cantley, Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 441, 424-430 (2006)
    • (2006) Nature , vol.441 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 42
    • 35348954836 scopus 로고    scopus 로고
    • UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway
    • A. Rapisarda, G. Melillo, UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway. Oncogene 26, 6875-6884 (2007)
    • (2007) Oncogene , vol.26 , pp. 6875-6884
    • Rapisarda, A.1    Melillo, G.2
  • 43
    • 33646550165 scopus 로고    scopus 로고
    • Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells
    • E. Connolly, S. Braunstein, S. Formenti, R.J. Schneider, Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. Mol. Cell. Biol. 26, 3955-3965 (2006)
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 3955-3965
    • Connolly, E.1    Braunstein, S.2    Formenti, S.3    Schneider, R.J.4
  • 45
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • D.A. Guertin, D.M. Sabatini, Defining the role of mTOR in cancer. Cancer Cell 12, 9-22 (2007)
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 47
    • 62449203027 scopus 로고    scopus 로고
    • Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression
    • K. Zhu, W. Chan, J. Heymach, M. Wilkinson, D.J. McConkey, Control of HIF-1alpha expression by eIF2 alpha phosphorylation-mediated translational repression. Cancer Res. 69, 1836-1843 (2009)
    • (2009) Cancer Res. , vol.69 , pp. 1836-1843
    • Zhu, K.1    Chan, W.2    Heymach, J.3    Wilkinson, M.4    McConkey, D.J.5
  • 48
    • 0036837864 scopus 로고    scopus 로고
    • Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
    • C. Koumenis, C. Naczki, M. Koritzinsky, S. Rastani, A. Diehl, N. Sonenberg, A. Koromilas, B.G. Wouters, Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol. Cell. Biol. 22, 7405-7416 (2002)
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7405-7416
    • Koumenis, C.1    Naczki, C.2    Koritzinsky, M.3    Rastani, S.4    Diehl, A.5    Sonenberg, N.6    Koromilas, A.7    Wouters, B.G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.