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Volumn 54, Issue 4, 2014, Pages 573-597

Pluronic F127-based thermosensitive gels for delivery of therapeutic proteins and peptides

Author keywords

Pluronic; proteinous drugs; sustained delivery; therapeutic proteins; thermosensitive gel

Indexed keywords

BIOCHEMISTRY; BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; FUNCTIONAL POLYMERS; GELS;

EID: 84906853381     PISSN: 15583724     EISSN: 15583716     Source Type: Journal    
DOI: 10.1080/15583724.2014.927885     Document Type: Review
Times cited : (71)

References (138)
  • 1
    • 33745190502 scopus 로고    scopus 로고
    • Biodegradable microspheres for parenteral delivery
    • Sinha, V. R.; Trehan, A. "Biodegradable microspheres for parenteral delivery", Crit. Rev. Ther. Drug Carrier Syst. 2005, 22, 535-602.
    • (2005) Crit. Rev. Ther. Drug Carrier Syst. , vol.22 , pp. 535-602
    • Sinha, V.R.1    Trehan, A.2
  • 3
    • 34248577169 scopus 로고    scopus 로고
    • Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs
    • Chiappetta, D. A.; Sosnik, A. "Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability and bioavailability of drugs", Eur. J. Pharm. Biopharm. 2007, 66, 303-317.
    • (2007) Eur. J. Pharm. Biopharm. , vol.66 , pp. 303-317
    • Chiappetta, D.A.1    Sosnik, A.2
  • 4
    • 77953360626 scopus 로고    scopus 로고
    • Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles
    • Agüeros, M.; Zabaleta, V.; Espuelas, S.; Campanero, M. A.; Irache, J. M. "Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles", J. Control. Release 2010, 145, 2-8.
    • (2010) J. Control. Release , vol.145 , pp. 2-8
    • Agüeros, M.1    Zabaleta, V.2    Espuelas, S.3    Campanero, M.A.4    Irache, J.M.5
  • 5
    • 2342424322 scopus 로고    scopus 로고
    • New technologies for drug delivery across the blood brain barrier
    • Kabanov, A. V.; Batrakova, E. V. "New technologies for drug delivery across the blood brain barrier", Curr. Pharm. Des. 2004, 10, 1355-1363.
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 1355-1363
    • Kabanov, A.V.1    Batrakova, E.V.2
  • 6
    • 11844271939 scopus 로고    scopus 로고
    • Non-viral gene delivery for local and controlled DNA release
    • Trentin, D.; Hubbell, J.; Hall, H. "Non-viral gene delivery for local and controlled DNA release", J. Control. Release 2005, 102, 263-275.
    • (2005) J. Control. Release , vol.102 , pp. 263-275
    • Trentin, D.1    Hubbell, J.2    Hall, H.3
  • 7
    • 33751512735 scopus 로고    scopus 로고
    • Polymeric micelles for drug delivery
    • Croy, S. R.; Kwon, G. S. "Polymeric micelles for drug delivery", Curr. Pharm. Des. 2006, 12, 4669-4684.
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 4669-4684
    • Croy, S.R.1    Kwon, G.S.2
  • 8
    • 49749101644 scopus 로고    scopus 로고
    • Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers
    • Batrakova, E. V.; Kabanov, A. V. "Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers", J. Control. Release 2008, 130, 98-106.
    • (2008) J. Control. Release , vol.130 , pp. 98-106
    • Batrakova, E.V.1    Kabanov, A.V.2
  • 9
    • 0142210489 scopus 로고    scopus 로고
    • Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers
    • Jeong, B.; Bae, Y. H.; Kim, S. W. "Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers", J. Control. Release 2000, 63, 155-163.
    • (2000) J. Control. Release , vol.63 , pp. 155-163
    • Jeong, B.1    Bae, Y.H.2    Kim, S.W.3
  • 10
    • 17344370674 scopus 로고    scopus 로고
    • Sloweroding biodegradable multiblock poloxamer
    • Ahn, J. S.; Suh, J. M.; Lee, M.Y.; Jeong, B. "Sloweroding biodegradable multiblock poloxamer", Polym. Int. 2005, 54, 842-847.
    • (2005) Polym. Int. , vol.54 , pp. 842-847
    • Ahn, J.S.1    Suh, J.M.2    Lee, M.Y.3    Jeong, B.4
  • 11
    • 77955571111 scopus 로고    scopus 로고
    • Biodegradability and biocompatibility of thermoreversible hydrogels formed from mixing a sol and a precipitate of block copolymers in water
    • Yu, L.; Zhang, Z.; Zhang, H.; Ding, J. "Biodegradability and biocompatibility of thermoreversible hydrogels formed from mixing a sol and a precipitate of block copolymers in water", Biomacromolecules 2010, 11, 2169-2178.
    • (2010) Biomacromolecules , vol.11 , pp. 2169-2178
    • Yu, L.1    Zhang, Z.2    Zhang, H.3    Ding, J.4
  • 13
    • 1042298979 scopus 로고    scopus 로고
    • Ethoxysilane-capped PEO-PPO-PEO triblocks: A new family of reverse thermo-responsive polymers
    • Sosnik, A.; Cohn, D. "Ethoxysilane-capped PEO-PPO-PEO triblocks: a new family of reverse thermo-responsive polymers", Biomaterials 2004, 25, 2851-2858.
    • (2004) Biomaterials , vol.25 , pp. 2851-2858
    • Sosnik, A.1    Cohn, D.2
  • 14
    • 84870566511 scopus 로고    scopus 로고
    • Thermoresponsive sodium alginate-g-poly(Nisopropylacrylamide) copolymers. III. Solution properties
    • Cheaburu, C.; Ciocoiu, O.; Staikos, G.; Vasile, C. "Thermoresponsive sodium alginate-g-poly(Nisopropylacrylamide) copolymers. III. Solution properties", J. Appl. Polym. Sci. 2013, 127, 3340-3348.
    • (2013) J. Appl. Polym. Sci. , vol.127 , pp. 3340-3348
    • Cheaburu, C.1    Ciocoiu, O.2    Staikos, G.3    Vasile, C.4
  • 15
    • 0031833574 scopus 로고    scopus 로고
    • Comparative study of the use of poly(glycolic acid), calcium alginate and pluronics in the engineering of autologous porcine cartilage
    • Cao, Y.; Rodriguez, A.; Vacanti, M.; Ibarra, C.; Arevalo, C.; Vacanti, C. A. "Comparative study of the use of poly(glycolic acid), calcium alginate and pluronics in the engineering of autologous porcine cartilage", J. Biomater. Sci. Polym. Ed. 1998, 9, 475-487.
    • (1998) J. Biomater. Sci. Polym. Ed. , vol.9 , pp. 475-487
    • Cao, Y.1    Rodriguez, A.2    Vacanti, M.3    Ibarra, C.4    Arevalo, C.5    Vacanti, C.A.6
  • 16
    • 23644440992 scopus 로고    scopus 로고
    • Semi-synthetic collagen/poloxamine matrices for Tissue Engineering applications
    • Sosnik, A.; Sefton, M. V. "Semi-synthetic collagen/poloxamine matrices for Tissue Engineering applications", Biomaterials 2005, 26, 7425-7435.
    • (2005) Biomaterials , vol.26 , pp. 7425-7435
    • Sosnik, A.1    Sefton, M.V.2
  • 17
    • 0001137517 scopus 로고    scopus 로고
    • Properties of aqueous solutions and gels of poly(ethylene oxide)-b poly(propylene oxide)-b-poly(ethylene oxide)-g-poly(acrylic acid)
    • Bromberg, L. "Properties of aqueous solutions and gels of poly(ethylene oxide)-b poly(propylene oxide)-b-poly(ethylene oxide)-g-poly(acrylic acid)", J. Phys. Chem. B 1998, 102, 10736-10744.
    • (1998) J. Phys. Chem. B , vol.102 , pp. 10736-10744
    • Bromberg, L.1
  • 18
    • 0036000109 scopus 로고    scopus 로고
    • Pluronic block copolymers in drug delivery: From micellar nanocontainers to biological response modifiers
    • Kabanov, A.; Alakhov, V. "Pluronic block copolymers in drug delivery: from micellar nanocontainers to biological response modifiers", Crit. Rev. Ther. Drug. Carr. Syst. 2002, 19, 1-72.
    • (2002) Crit. Rev. Ther. Drug. Carr. Syst. , vol.19 , pp. 1-72
    • Kabanov, A.1    Alakhov, V.2
  • 19
    • 0030824333 scopus 로고    scopus 로고
    • Drug delivery matrix containing native protein precipitates suspended in a polo-maxamer gel
    • Stratton, L. P.; Dong, A.; Manning, M. C.; Carpenter, J. F. "Drug delivery matrix containing native protein precipitates suspended in a polo-maxamer gel", J. Pharm. Sci. 1997, 86, 1006-1010.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 1006-1010
    • Stratton, L.P.1    Dong, A.2    Manning, M.C.3    Carpenter, J.F.4
  • 20
    • 84897979761 scopus 로고    scopus 로고
    • Assessment of release kinetics, stability and polymer interaction of PF127-based thermosensitive gel of interleutkin-1 receptor antagonist
    • Akash, M. S. H.; Rehman, K.; Sun, H.; Chen, S. "Assessment of release kinetics, stability and polymer interaction of PF127-based thermosensitive gel of interleutkin-1 receptor antagonist", Pharm. Dev. Technol. 2014, 19, 278-284.
    • (2014) Pharm. Dev. Technol. , vol.19 , pp. 278-284
    • Akash, M.S.H.1    Rehman, K.2    Sun, H.3    Chen, S.4
  • 21
    • 84872915463 scopus 로고    scopus 로고
    • Thermosensitive polymeric hydrogels as drug delivery systems
    • Gong, C.; Qi, T.; Wei, X.; Qu, Y.; Wu, Q.; Luo, F.; Qian, Z. "Thermosensitive polymeric hydrogels as drug delivery systems", Curr. Med. Chem. 2013, 20, 79-94.
    • (2013) Curr. Med. Chem. , vol.20 , pp. 79-94
    • Gong, C.1    Qi, T.2    Wei, X.3    Qu, Y.4    Wu, Q.5    Luo, F.6    Qian, Z.7
  • 22
    • 75149178099 scopus 로고    scopus 로고
    • The biocompatibility of PluronicF127 fibrinogen-based hydrogels
    • Shachaf, Y.; Gonen-Wadmany, M.; Seliktar, D. "The biocompatibility of PluronicF127 fibrinogen-based hydrogels", Biomaterials 2010, 31, 2836-2847.
    • (2010) Biomaterials , vol.31 , pp. 2836-2847
    • Shachaf, Y.1    Gonen-Wadmany, M.2    Seliktar, D.3
  • 23
    • 84879718965 scopus 로고    scopus 로고
    • Study in vivo intraocular biocompatibility of in situ gelation hydrogels: Poly(2-ethyl oxazoline)-block-poly(∈-caprolactone)-block-poly(2-ethyl oxazoline) copolymer, matrigel and pluronic F127
    • Hwang, Y.S.; Chiang, P. R.; Hong, W. H.; Chiao, C. C.; Chu, I. M.; Hsiue, G. H.; Shen, C. R. "Study in vivo intraocular biocompatibility of in situ gelation hydrogels: poly(2-ethyl oxazoline)-block-poly(∈-caprolactone)- block-poly(2-ethyl oxazoline) copolymer, matrigel and pluronic F127", PLoS One 2013, 8, e67495.
    • (2013) PLoS One , vol.8
    • Hwang, Y.S.1    Chiang, P.R.2    Hong, W.H.3    Chiao, C.C.4    Chu, I.M.5    Hsiue, G.H.6    Shen, C.R.7
  • 24
    • 84870238521 scopus 로고    scopus 로고
    • Thermosensitive sol-gel reversible hydrogels
    • Jeong, B.; Kim, S. W.; Bae, Y. H. "Thermosensitive sol-gel reversible hydrogels", Adv Drug Deliv. Rev. 2012, 64, 154-162.
    • (2012) Adv Drug Deliv. Rev. , vol.64 , pp. 154-162
    • Jeong, B.1    Kim, S.W.2    Bae, Y.H.3
  • 26
    • 84873668406 scopus 로고    scopus 로고
    • Sustained delivery of IL-1Ra from PF127 gel reduces hyperglycemia in diabetic GK rats
    • Akash, M. S. H.; Rehman, K.; Sun, H.; Chen, S. "Sustained delivery of IL-1Ra from PF127 gel reduces hyperglycemia in diabetic GK rats", PLoS One 2013, 8, e55925.
    • (2013) PLoS One , vol.8
    • Akash, M.S.H.1    Rehman, K.2    Sun, H.3    Chen, S.4
  • 27
    • 84882770398 scopus 로고    scopus 로고
    • Goto-kakizaki rats: Its suitability as non-obese diabetic animal model for spontaneous type 2 diabetes mellitus
    • Akash, M. S. H.; Rehman, K.; Chen, S. "Goto-kakizaki rats: Its suitability as non-obese diabetic animal model for spontaneous type 2 diabetes mellitus", Curr Diabetes Rev. 2013, 9, 387-396.
    • (2013) Curr Diabetes Rev. , vol.9 , pp. 387-396
    • Akash, M.S.H.1    Rehman, K.2    Chen, S.3
  • 28
    • 27744593478 scopus 로고    scopus 로고
    • Concentration, temperature, and salt-induced micellization of a triblock copolymer Pluronic L64 in aqueous media
    • Mata, J. P.; Majhi, P. R.; Guo, C.; Liu, H. Z.; Bahadur, P. "Concentration, temperature, and salt-induced micellization of a triblock copolymer Pluronic L64 in aqueous media", J. Colloid Interf. Sci. 2005, 292, 548-556.
    • (2005) J. Colloid Interf. Sci. , vol.292 , pp. 548-556
    • Mata, J.P.1    Majhi, P.R.2    Guo, C.3    Liu, H.Z.4    Bahadur, P.5
  • 29
    • 0037122783 scopus 로고    scopus 로고
    • ABA-triblock copolymers from biodegradable polyester A-blocks and hydrophilic poly(ethylene oxide)B-blocks as a candidate for in situ forming hydrogel delivery systems for proteins
    • Kissel, T.; Li, Y.; Unger, F. "ABA-triblock copolymers from biodegradable polyester A-blocks and hydrophilic poly(ethylene oxide)B-blocks as a candidate for in situ forming hydrogel delivery systems for proteins", Adv. Drug Deliver. Rev. 2002, 54, 99-134.
    • (2002) Adv. Drug Deliver. Rev. , vol.54 , pp. 99-134
    • Kissel, T.1    Li, Y.2    Unger, F.3
  • 30
    • 3843071010 scopus 로고    scopus 로고
    • In situ-forming hydrogels: Review of temperature-sensitive systems
    • Gariépy, E. R.; Leroux, J. C. "In situ-forming hydrogels: Review of temperature-sensitive systems", Eur. J. Pharm. Biopharm. 2004, 58, 409-426.
    • (2004) Eur. J. Pharm. Biopharm. , vol.58 , pp. 409-426
    • Gariépy, E.R.1    Leroux, J.C.2
  • 31
    • 32944455473 scopus 로고    scopus 로고
    • Perspectives on: PEO-PPO-PEO triblock copolymers and their biomedical applications
    • Fusco, S.; Borzacchiello, A.; Netti, P. "Perspectives on: PEO-PPO-PEO triblock copolymers and their biomedical applications", J. Bioact. Compat. Polym. 2006, 21, 149-164.
    • (2006) J. Bioact. Compat. Polym. , vol.21 , pp. 149-164
    • Fusco, S.1    Borzacchiello, A.2    Netti, P.3
  • 32
    • 42049097246 scopus 로고    scopus 로고
    • In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery
    • He, C.; Kim, S. W.; Lee, D. S. "In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery", J. Control. Release 2008, 127, 189-207.
    • (2008) J. Control. Release , vol.127 , pp. 189-207
    • He, C.1    Kim, S.W.2    Lee, D.S.3
  • 35
    • 35448933201 scopus 로고    scopus 로고
    • Photo-cross-linkable and thermo-responsive hydrogels containing chitosan and Pluronic for sustained release of human growth hormone (hGH)
    • Yoo, H. S. "Photo-cross-linkable and thermo-responsive hydrogels containing chitosan and Pluronic for sustained release of human growth hormone (hGH)", J. Biomater. Sci. Polymer. Ed. 2007, 18, 1429-1441.
    • (2007) J. Biomater. Sci. Polymer. Ed. , vol.18 , pp. 1429-1441
    • Yoo, H.S.1
  • 36
    • 67651180535 scopus 로고    scopus 로고
    • Synergistic anti-tumor activity of paclitaxel-incorporated conjugated linoleic acid-coupled poloxamer thermosensitive hydrogel in vitro and in vivo
    • Guo, D. D.; Xu, C. X.; Quan, J. S.; Song, C. K.; Jin, H.; Kim, D. D.; Choi, Y. J.; Cho, M. H.; Cho, C. S. "Synergistic anti-tumor activity of paclitaxel-incorporated conjugated linoleic acid-coupled poloxamer thermosensitive hydrogel in vitro and in vivo", Biomaterials 2009, 30, 4777-4785.
    • (2009) Biomaterials , vol.30 , pp. 4777-4785
    • Guo, D.D.1    Xu, C.X.2    Quan, J.S.3    Song, C.K.4    Jin, H.5    Kim, D.D.6    Choi, Y.J.7    Cho, M.H.8    Cho, C.S.9
  • 37
    • 65949099703 scopus 로고    scopus 로고
    • Physicochemical characterization and drug release of thermosensitive hydrogels composed of a hyaluronic acid/Pluronic F127 graft
    • Hsu, S.; Leu, Y.; Hu, J.; Fang, J. "Physicochemical characterization and drug release of thermosensitive hydrogels composed of a hyaluronic acid/Pluronic F127 graft", Chem. Pharm. Bull. 2009, 57, 453-458.
    • (2009) Chem. Pharm. Bull. , vol.57 , pp. 453-458
    • Hsu, S.1    Leu, Y.2    Hu, J.3    Fang, J.4
  • 38
    • 67649122351 scopus 로고    scopus 로고
    • Delivery of cisplatin from Pluronic co-polymer systems: Liposome inclusion and alginate coupling
    • Fang, J.; Hsu, S.; Leu, Y.; Hu, J. "Delivery of cisplatin from Pluronic co-polymer systems: liposome inclusion and alginate coupling", J. Biomat. Sci. Polym. E 2009, 20, 1031-1047.
    • (2009) J. Biomat. Sci. Polym. E , vol.20 , pp. 1031-1047
    • Fang, J.1    Hsu, S.2    Leu, Y.3    Hu, J.4
  • 39
    • 1642541103 scopus 로고    scopus 로고
    • Polymeric micelles for delivery of poorly water-soluble compounds
    • Kwon, G. S. "Polymeric micelles for delivery of poorly water-soluble compounds", Crit. Rev. Ther. Drug Carr. Syst. 2003, 20, 357-403.
    • (2003) Crit. Rev. Ther. Drug Carr. Syst. , vol.20 , pp. 357-403
    • Kwon, G.S.1
  • 41
    • 84872064405 scopus 로고    scopus 로고
    • Sustained delivery of IL-1Ra from Pluronic F127-based thermosensitive gel prolongs its therapeutic potentials
    • Akash, M. S. H.; Rehman, K.; Li, N.; Gao, J. Q.; Sun, H.; Chen, S. "Sustained delivery of IL-1Ra from Pluronic F127-based thermosensitive gel prolongs its therapeutic potentials", Pharm. Res. 2012, 29, 3475-3485.
    • (2012) Pharm. Res. , vol.29 , pp. 3475-3485
    • Akash, M.S.H.1    Rehman, K.2    Li, N.3    Gao, J.Q.4    Sun, H.5    Chen, S.6
  • 42
    • 0031800878 scopus 로고    scopus 로고
    • Effects of pluronic block copolymers on drug absorption in Caco-2 cell monolayers
    • Batrakova, E.; Han, H.; Alakhov, V.; Miller, D.; Kabanov, A. "Effects of pluronic block copolymers on drug absorption in Caco-2 cell monolayers", Pharm. Res. 1998, 15, 850-855.
    • (1998) Pharm. Res. , vol.15 , pp. 850-855
    • Batrakova, E.1    Han, H.2    Alakhov, V.3    Miller, D.4    Kabanov, A.5
  • 44
    • 0037457792 scopus 로고    scopus 로고
    • Pluronic block copolymers as modulators of drug efflux transporter activity in the blood-brain barrier
    • Kabanov, A. V.; Batrakova, E. V.; Miller, D. W. "Pluronic block copolymers as modulators of drug efflux transporter activity in the blood-brain barrier", Adv. Drug Deliv. Rev. 2003, 55, 151-164.
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 151-164
    • Kabanov, A.V.1    Batrakova, E.V.2    Miller, D.W.3
  • 46
    • 34347374069 scopus 로고    scopus 로고
    • Effect of intratumoral injection of carboplatin combined with pluronic P85 or L61 on experimental colorectal carcinoma in rats
    • Krupka, T.M.; Weinberg, B.D.; Wu, H.; Ziats, N. P.; Exner, A. A. "Effect of intratumoral injection of carboplatin combined with pluronic P85 or L61 on experimental colorectal carcinoma in rats", Exp. Biol. Med. 2007, 232, 950-957.
    • (2007) Exp. Biol. Med. , vol.232 , pp. 950-957
    • Krupka, T.M.1    Weinberg, B.D.2    Wu, H.3    Ziats, N.P.4    Exner, A.A.5
  • 47
    • 1242271298 scopus 로고    scopus 로고
    • The effects of Pluronic block copolymers on the aggregation state of nystatin
    • Croy, S. R.; Kwon, G. S. "The effects of Pluronic block copolymers on the aggregation state of nystatin", J. Control. Release 2004, 95, 161-171.
    • (2004) J. Control. Release , vol.95 , pp. 161-171
    • Croy, S.R.1    Kwon, G.S.2
  • 48
    • 30544441982 scopus 로고    scopus 로고
    • Polysorbate 80 and Cremophor EL micelles deaggregate and solubilize nystatin at the core-corona interface
    • Croy, S. R.; Kwon, G. S. "Polysorbate 80 and Cremophor EL micelles deaggregate and solubilize nystatin at the core-corona interface", J. Pharm. Sci. 2005, 94, 2345-2354.
    • (2005) J. Pharm. Sci. , vol.94 , pp. 2345-2354
    • Croy, S.R.1    Kwon, G.S.2
  • 49
    • 0026542159 scopus 로고
    • Sustained delivery of interleukin-2 from a poloxamer 407 gel matrix following intraperitoneal injection in mice
    • Johnston, T. P.; Punjabi, M. A.; Froelich, C. J. "Sustained delivery of interleukin-2 from a poloxamer 407 gel matrix following intraperitoneal injection in mice", Pharm. Res. 1992, 9, 425-434.
    • (1992) Pharm. Res. , vol.9 , pp. 425-434
    • Johnston, T.P.1    Punjabi, M.A.2    Froelich, C.J.3
  • 50
    • 0028949713 scopus 로고
    • Sustained-release interleukin-2 following intramuscular injection in rats
    • Wang, P. L.; Johnston, T. P. "Sustained-release interleukin-2 following intramuscular injection in rats", Int. J. Pharm. 1995, 113, 73-81.
    • (1995) Int. J. Pharm. , vol.113 , pp. 73-81
    • Wang, P.L.1    Johnston, T.P.2
  • 51
    • 33645380133 scopus 로고    scopus 로고
    • Investigation on recombinant hirudin via oral route
    • Cen, X.; Ni, J.; Tan, T. "Investigation on recombinant hirudin via oral route", Peptides 2006, 27, 836-840.
    • (2006) Peptides , vol.27 , pp. 836-840
    • Cen, X.1    Ni, J.2    Tan, T.3
  • 53
    • 84863712145 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist: A new therapy for type 2 diabetes mellitus
    • Akash, M. S. H.; Shen, Q.; Rehman, K.; Chen, S. "Interleukin-1 receptor antagonist: A new therapy for type 2 diabetes mellitus", J. Pharm. Sci. 2012, 101, 1647-1658.
    • (2012) J. Pharm. Sci. , vol.101 , pp. 1647-1658
    • Akash, M.S.H.1    Shen, Q.2    Rehman, K.3    Chen, S.4
  • 54
    • 84872772714 scopus 로고    scopus 로고
    • Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus
    • Akash, M. S. H.; Rehman, K.; Chen, S. "Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus", J. Cell. Biochem. 2013, 114, 525-531.
    • (2013) J. Cell. Biochem. , vol.114 , pp. 525-531
    • Akash, M.S.H.1    Rehman, K.2    Chen, S.3
  • 55
    • 84882805182 scopus 로고    scopus 로고
    • An overview of valuable scientific models for diabetes mellitus
    • Akash, M. S. H.; Rehman, K.; Chen, S. "An overview of valuable scientific models for diabetes mellitus", Curr. Diabetes Rev. 2013, 9(4), 286-293.
    • (2013) Curr. Diabetes Rev. , vol.9 , Issue.4 , pp. 286-293
    • Akash, M.S.H.1    Rehman, K.2    Chen, S.3
  • 57
    • 84898412790 scopus 로고    scopus 로고
    • Effects of coffee on type 2 diabetes mellitus
    • Akash, M. S. H.; Rehman, K.; Chen, S. "Effects of coffee on type 2 diabetes mellitus", Nutrition 2014, 30, 755-763.
    • (2014) Nutrition , vol.30 , pp. 755-763
    • Akash, M.S.H.1    Rehman, K.2    Chen, S.3
  • 58
    • 84900474865 scopus 로고    scopus 로고
    • Spice plant Allium cepa: Dietary supplement for treatment of type 2 diabetes mellitus
    • DOI: 10.1016/j.nut.2014.02.011
    • Akash, M. S. H.; Rehman, K.; Chen, S. "Spice plant Allium cepa: Dietary supplement for treatment of type 2 diabetes mellitus", Nutrition 2014, DOI: 10.1016/j.nut.2014.02.011.
    • (2014) Nutrition
    • Akash, M.S.H.1    Rehman, K.2    Chen, S.3
  • 60
    • 84873693337 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist improves normoglycemia and insulin sensitivity in diabetic Goto-Kakizaki-rats
    • Akash, M. S. H.; Rehman, K.; Chen, S. "Interleukin-1 receptor antagonist improves normoglycemia and insulin sensitivity in diabetic Goto-Kakizaki-rats", Eur. J. Pharmacol. 2013, 701, 87-95.
    • (2013) Eur. J. Pharmacol. , vol.701 , pp. 87-95
    • Akash, M.S.H.1    Rehman, K.2    Chen, S.3
  • 61
    • 84886098158 scopus 로고    scopus 로고
    • IL-1Ra and its delivery strategies: Inserting the association in perspective
    • Akash, M. S. H.; Rehman, K.; Chen, S. "IL-1Ra and its delivery strategies: Inserting the association in perspective", Pharm Res. 2013, 30, 2951-2966.
    • (2013) Pharm Res. , vol.30 , pp. 2951-2966
    • Akash, M.S.H.1    Rehman, K.2    Chen, S.3
  • 62
    • 33745654791 scopus 로고    scopus 로고
    • The role of basal insulin therapy in patients with type 2 diabetes mellitus
    • Fonseca, V. "The role of basal insulin therapy in patients with type 2 diabetes mellitus", Insulin 2006, 1, 51-60.
    • (2006) Insulin , vol.1 , pp. 51-60
    • Fonseca, V.1
  • 63
    • 0038641805 scopus 로고    scopus 로고
    • New developments in insulin delivery
    • Ghilzai, N. M. K. "New developments in insulin delivery", Drug Dev. Ind. Pharm. 2003, 29, 253-265.
    • (2003) Drug Dev. Ind. Pharm. , vol.29 , pp. 253-265
    • Ghilzai, N.M.K.1
  • 64
    • 0033016761 scopus 로고    scopus 로고
    • Absorption of insulin from Pluronic F-127 gels following subcutaneous administration in rats
    • Barichello, J. M.; Morishita, M.; Takayama, K.; Nagai, T. "Absorption of insulin from Pluronic F-127 gels following subcutaneous administration in rats", Int. J. Pharm. 1999, 184, 189-198.
    • (1999) Int. J. Pharm. , vol.184 , pp. 189-198
    • Barichello, J.M.1    Morishita, M.2    Takayama, K.3    Nagai, T.4
  • 65
    • 33750181786 scopus 로고    scopus 로고
    • Triblock copolymer Pluronic F127 sustains insulin release and reduces initial burst of microspheres-in vitro and in vivo study
    • Wang, Y.; Gao, J.; Li, F.; Ri, S.; Liang, W. "Triblock copolymer Pluronic F127 sustains insulin release and reduces initial burst of microspheres-in vitro and in vivo study", Colloid. Polym. Sci. 2006, 285, 233-238.
    • (2006) Colloid. Polym. Sci. , vol.285 , pp. 233-238
    • Wang, Y.1    Gao, J.2    Li, F.3    Ri, S.4    Liang, W.5
  • 67
    • 0032996796 scopus 로고    scopus 로고
    • Enhanced rectal absorption of insulin-loaded Pluronic F-127gels containing unsaturated fatty acids
    • Barichello, J. M.; Morishita, M.; Takayama, K.; Chiba, Y.; Tokiwa, S.; Nagai, T. "Enhanced rectal absorption of insulin-loaded Pluronic F-127gels containing unsaturated fatty acids", Int. J. Pharm. 1999, 183, 125-132.
    • (1999) Int. J. Pharm. , vol.183 , pp. 125-132
    • Barichello, J.M.1    Morishita, M.2    Takayama, K.3    Chiba, Y.4    Tokiwa, S.5    Nagai, T.6
  • 68
    • 0035895143 scopus 로고    scopus 로고
    • Pluronic F-127 gels incorporating highly purified unsaturated fatty acids for buccal delivery of insulin
    • Morishita, M.; Barichello, J.M.; Takayama, K.; Chiba, Y.; Tokiwa, S.; Nagai, T. "Pluronic F-127 gels incorporating highly purified unsaturated fatty acids for buccal delivery of insulin", Int. J. Pharm. 2001, 212, 289-293.
    • (2001) Int. J. Pharm. , vol.212 , pp. 289-293
    • Morishita, M.1    Barichello, J.M.2    Takayama, K.3    Chiba, Y.4    Tokiwa, S.5    Nagai, T.6
  • 69
    • 77949367331 scopus 로고    scopus 로고
    • Development and in vitro evaluation of insulin-loaded buccal Pluronic F-127 gels
    • Das, N.; Madan, P.; Lin, S. "Development and in vitro evaluation of insulin-loaded buccal Pluronic F-127 gels", Pharm. Dev. Technol. 2010, 15, 192-208.
    • (2010) Pharm. Dev. Technol. , vol.15 , pp. 192-208
    • Das, N.1    Madan, P.2    Lin, S.3
  • 70
    • 84859977179 scopus 로고    scopus 로고
    • Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin
    • Das, N.; Madan, P.; Lin, S. "Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin", Pharm. Dev. Technol. 2012, 17, 363-374.
    • (2012) Pharm. Dev. Technol. , vol.17 , pp. 363-374
    • Das, N.1    Madan, P.2    Lin, S.3
  • 71
    • 0037437032 scopus 로고    scopus 로고
    • Transdermal delivery of insulin from poloxamer gel: Ex vivo and in vivo skin permeation studies in rat using iontophoresis and chemical enhancers
    • Pillai, O.; Panchagnula, R. "Transdermal delivery of insulin from poloxamer gel: Ex vivo and in vivo skin permeation studies in rat using iontophoresis and chemical enhancers", J. Control. Release 2003, 89, 127-140.
    • (2003) J. Control. Release , vol.89 , pp. 127-140
    • Pillai, O.1    Panchagnula, R.2
  • 72
    • 0031132437 scopus 로고    scopus 로고
    • Ovarian follicular cysts in dairy cows
    • Garverick, H. A. "Ovarian follicular cysts in dairy cows", J. Dairy Sci. 1997, 80, 995-1004.
    • (1997) J. Dairy Sci. , vol.80 , pp. 995-1004
    • Garverick, H.A.1
  • 74
    • 0037073641 scopus 로고    scopus 로고
    • Pluronic F127 gel formulations of Deslorelin and GnRH reduce drug degradation and sustain drug release and effect in cattle
    • Wenzel, J. G.; Balaji, K. S.; Koushik, K.; Navarre, C.; Duran, S. H.; Rahe, C. H.; Kompella, U.B. "Pluronic F127 gel formulations of Deslorelin and GnRH reduce drug degradation and sustain drug release and effect in cattle", J. Control. Release 2002, 85, 51-59.
    • (2002) J. Control. Release , vol.85 , pp. 51-59
    • Wenzel, J.G.1    Balaji, K.S.2    Koushik, K.3    Navarre, C.4    Duran, S.H.5    Rahe, C.H.6    Kompella, U.B.7
  • 75
    • 33845201165 scopus 로고    scopus 로고
    • Effect of molecular size of PEGylated recombinant human epidermal growth factor on the biological activity and stability in rat wound tissue
    • Na, D. H.; Youn, Y. S.; Lee, I. B.; Park, E. J.; Park, C. J.; Choon, K. L. "Effect of molecular size of PEGylated recombinant human epidermal growth factor on the biological activity and stability in rat wound tissue", Pharm. Dev. Technol. 2006, 11, 513-519.
    • (2006) Pharm. Dev. Technol. , vol.11 , pp. 513-519
    • Na, D.H.1    Youn, Y.S.2    Lee, I.B.3    Park, E.J.4    Park, C.J.5    Choon, K.L.6
  • 76
    • 80054761015 scopus 로고    scopus 로고
    • Protein stabilization by cyclodextrins in the liquid and dried state
    • Serno, T.; Geidobler, R.; Winter, G. "Protein stabilization by cyclodextrins in the liquid and dried state", Adv. Drug Deliv. Rev. 2011, 63, 1086-1106.
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 1086-1106
    • Serno, T.1    Geidobler, R.2    Winter, G.3
  • 77
    • 80054887741 scopus 로고    scopus 로고
    • Modification of proteins with cyclodextrins prevents aggregation and surface adsorption and increases thermal stability
    • Prashar, D.; Cui, D.; Bandyopadhyay, D.; Luk, Y. Y. "Modification of proteins with cyclodextrins prevents aggregation and surface adsorption and increases thermal stability", Langmuir 2011, 27, 13091-13096.
    • (2011) Langmuir , vol.27 , pp. 13091-13096
    • Prashar, D.1    Cui, D.2    Bandyopadhyay, D.3    Luk, Y.Y.4
  • 78
    • 0037148668 scopus 로고    scopus 로고
    • RhEGF/HP-β-CD complex in poloxamer gel for ophthalmic delivery
    • Kim, E. Y.; Gao, Z. G.; Park, J. S.; Li, H.; Han, K. "rhEGF/HP- β-CD complex in poloxamer gel for ophthalmic delivery", Int. J. Pharm. 2002, 233, 159-167.
    • (2002) Int. J. Pharm. , vol.233 , pp. 159-167
    • Kim, E.Y.1    Gao, Z.G.2    Park, J.S.3    Li, H.4    Han, K.5
  • 79
    • 78649286686 scopus 로고    scopus 로고
    • Pluronic/chitosan hydrogels containing epidermal growth factor with wound-adhesive and photo-crosslinkable properties
    • Choi, J. S.; Yoo, H. S. "Pluronic/chitosan hydrogels containing epidermal growth factor with wound-adhesive and photo-crosslinkable properties", J. Biomed. Mater. Res. A. 2010, 95, 564-573.
    • (2010) J. Biomed. Mater. Res. A. , vol.95 , pp. 564-573
    • Choi, J.S.1    Yoo, H.S.2
  • 80
    • 0030826964 scopus 로고    scopus 로고
    • Controlled release of human growth hormone in rats following parenteral administration of poloxamer gels
    • Katakam, M.; Ravis, W. R.; Banga, A. K. "Controlled release of human growth hormone in rats following parenteral administration of poloxamer gels", J. Control. Release 1997, 49, 21-26.
    • (1997) J. Control. Release , vol.49 , pp. 21-26
    • Katakam, M.1    Ravis, W.R.2    Banga, A.K.3
  • 81
    • 0030918082 scopus 로고    scopus 로고
    • Controlled release of human growth hormone following subcutaneous administration in dogs
    • Katakam, M.; Ravis, W. R.; Golden, D. L.; Banga, A. K. "Controlled release of human growth hormone following subcutaneous administration in dogs", Int. J. Pharm. 1997, 152, 53-58.
    • (1997) Int. J. Pharm. , vol.152 , pp. 53-58
    • Katakam, M.1    Ravis, W.R.2    Golden, D.L.3    Banga, A.K.4
  • 82
    • 8744282349 scopus 로고    scopus 로고
    • Controlling degradation of acid-hydrolyzable Pluronic hydrogels by physical entrapment of poly(lactic acid-co-glycolic acid) microspheres
    • Lee, J. B.; Chun, K. W.; Yoon, J. J.; Park, T. G. "Controlling degradation of acid-hydrolyzable Pluronic hydrogels by physical entrapment of poly(lactic acid-co-glycolic acid) microspheres", Macromol. Biosci. 2004, 4, 957-962.
    • (2004) Macromol. Biosci. , vol.4 , pp. 957-962
    • Lee, J.B.1    Chun, K.W.2    Yoon, J.J.3    Park, T.G.4
  • 83
    • 10644250026 scopus 로고    scopus 로고
    • Controlled release of plasmid DNA from photo-cross-linked pluronic hydrogels
    • Chun, K. W.; Lee, J. B.; Kim, S. H.; Park, T. G. "Controlled release of plasmid DNA from photo-cross-linked pluronic hydrogels", Biomaterials 2005, 26, 3319-3326.
    • (2005) Biomaterials , vol.26 , pp. 3319-3326
    • Chun, K.W.1    Lee, J.B.2    Kim, S.H.3    Park, T.G.4
  • 84
    • 0037122788 scopus 로고    scopus 로고
    • Novel crosslinking methods to design hydrogels
    • Hennink, W. E.; van Nostrum, C. F. "Novel crosslinking methods to design hydrogels", Adv. Drug Deliv. Rev. 2002, 54, 13-36.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 13-36
    • Hennink, W.E.1    Van Nostrum, C.F.2
  • 85
    • 0037466417 scopus 로고    scopus 로고
    • Biopolymer stereocomplexes
    • Slager, J.; Domb, A. J. "Biopolymer stereocomplexes", Adv. Drug Del. Rev. 2003, 55, 549-583.
    • (2003) Adv. Drug Del. Rev. , vol.55 , pp. 549-583
    • Slager, J.1    Domb, A.J.2
  • 86
    • 0033744331 scopus 로고    scopus 로고
    • Novel self-assembled hydrogels by stereocomplex formation in aqueous solution of enantiomeric lactic acid oligomers grafted to dextran
    • de Jong, S. J.; De Smedt, S. C.; Wahls, M. W. C.; Demeester, J.; Kettenes-van den Bosch, J. J.; Hennink, W. E. "Novel self-assembled hydrogels by stereocomplex formation in aqueous solution of enantiomeric lactic acid oligomers grafted to dextran", Macromolecules 2000, 33, 3680-3686.
    • (2000) Macromolecules , vol.33 , pp. 3680-3686
    • De Jong, S.J.1    De Smedt, S.C.2    Wahls, M.W.C.3    Demeester, J.4    Kettenes-Van Den-Bosch, J.J.5    Hennink, W.E.6
  • 87
    • 23044517808 scopus 로고    scopus 로고
    • A new class of biodegradable hydrogels stereocomplexed between enantiomeric oligo-lactide side chains of poly (HEMA-g-OLA)s
    • Lim, D. W.; Choi, S. H.; Park, T. G. "A new class of biodegradable hydrogels stereocomplexed between enantiomeric oligo-lactide side chains of poly (HEMA-g-OLA)s", Macromol. Rap. Comm. 2000, 21, 464-471.
    • (2000) Macromol. Rap. Comm. , vol.21 , pp. 464-471
    • Lim, D.W.1    Choi, S.H.2    Park, T.G.3
  • 88
    • 2442694993 scopus 로고    scopus 로고
    • Biodegradable dextran hydrogels crosslinked by stereocomplex formation for the controlled release of pharmaceutical proteins
    • Hennink, W. E.; de Jong, S. J.; Bos, G. W.; Veldhuis, T. F. J.; van Nostrum, C. F. "Biodegradable dextran hydrogels crosslinked by stereocomplex formation for the controlled release of pharmaceutical proteins", Int. J. Pharm. 2004, 277, 99-104.
    • (2004) Int. J. Pharm. , vol.277 , pp. 99-104
    • Hennink, W.E.1    De Jong, S.J.2    Bos, G.W.3    Veldhuis, T.F.J.4    Van Nostrum, C.F.5
  • 89
    • 34548047242 scopus 로고    scopus 로고
    • Release of model proteins and basic fibroblast growth factor from in situ forming degradable dextran hydrogels
    • Hiemstra, C.; Zhong, Z.; van Steenbergen, M. J.; Hennink, W. E.; Feijen, J. "Release of model proteins and basic fibroblast growth factor from in situ forming degradable dextran hydrogels", J. Control. Release 2007, 122, 71-78.
    • (2007) J. Control. Release , vol.122 , pp. 71-78
    • Hiemstra, C.1    Zhong, Z.2    Van Steenbergen, M.J.3    Hennink, W.E.4    Feijen, J.5
  • 90
    • 40649101153 scopus 로고    scopus 로고
    • Thermo-sensitive and biodegradable hydrogels based on stereocomplexed Pluronic multi-block copolymers for controlled protein delivery
    • Chung, H. J.; Lee, Y.; Park, T. G. "Thermo-sensitive and biodegradable hydrogels based on stereocomplexed Pluronic multi-block copolymers for controlled protein delivery", J. Control. Release 2008, 127, 22-30.
    • (2008) J. Control. Release , vol.127 , pp. 22-30
    • Chung, H.J.1    Lee, Y.2    Park, T.G.3
  • 91
    • 0037161330 scopus 로고    scopus 로고
    • Temperature-responsive and degradable hyaluronic acid/Pluronic composite hydrogels for controlled release of human growth hormone
    • Kim, M. R.; Park, T. G. "Temperature-responsive and degradable hyaluronic acid/Pluronic composite hydrogels for controlled release of human growth hormone", J. Control. Release 2002, 80, 69-77.
    • (2002) J. Control. Release , vol.80 , pp. 69-77
    • Kim, M.R.1    Park, T.G.2
  • 93
    • 13844265668 scopus 로고    scopus 로고
    • Self-assembled nanoparticles containing hydrophobically modified glycol chitosan for gene delivery
    • Yoo, H. S.; Lee, J. E.; Chung, H.; Kwon, I. C.; Jeong, S. Y. "Self-assembled nanoparticles containing hydrophobically modified glycol chitosan for gene delivery", J. Control. Release 2005, 103, 235-243.
    • (2005) J. Control. Release , vol.103 , pp. 235-243
    • Yoo, H.S.1    Lee, J.E.2    Chung, H.3    Kwon, I.C.4    Jeong, S.Y.5
  • 94
    • 16344387352 scopus 로고    scopus 로고
    • PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release
    • Bhattarai, N.; Ramay, H. R.; Gunn, J.; Matsen, F. A.; Zhang, M. "PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release", J. Control. Release 2005, 103, 609-624.
    • (2005) J. Control. Release , vol.103 , pp. 609-624
    • Bhattarai, N.1    Ramay, H.R.2    Gunn, J.3    Matsen, F.A.4    Zhang, M.5
  • 95
    • 0037072576 scopus 로고    scopus 로고
    • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
    • Merdan, T.; Kopecek, J.; Kissel, T. "Prospects for cationic polymers in gene and oligonucleotide therapy against cancer", Adv. Drug Deliv. Rev. 2002, 54, 715-758.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 715-758
    • Merdan, T.1    Kopecek, J.2    Kissel, T.3
  • 96
    • 27844495150 scopus 로고    scopus 로고
    • Current developments in gene transfection agents
    • Azzam, T.; Domb, A. J. "Current developments in gene transfection agents", Curr. Drug Deliv. 2004, 1, 165-193.
    • (2004) Curr. Drug Deliv. , vol.1 , pp. 165-193
    • Azzam, T.1    Domb, A.J.2
  • 97
    • 21244441929 scopus 로고    scopus 로고
    • Immune responses to adeno-associated virus vectors
    • Zaiss, A. K.; Muruve, D. A. "Immune responses to adeno-associated virus vectors", Curr. Gene. Ther. 2005, 5, 323-331.
    • (2005) Curr. Gene. Ther. , vol.5 , pp. 323-331
    • Zaiss, A.K.1    Muruve, D.A.2
  • 98
    • 33645451483 scopus 로고    scopus 로고
    • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors
    • Baum, C.; Kustikova, O.; Modlich, U.; Li, Z.; Fehse, B. "Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors", Hum. Gene. Ther. 2006, 17, 253-263.
    • (2006) Hum. Gene. Ther. , vol.17 , pp. 253-263
    • Baum, C.1    Kustikova, O.2    Modlich, U.3    Li, Z.4    Fehse, B.5
  • 99
    • 33645242923 scopus 로고    scopus 로고
    • Pluronic block copolymers for gene delivery
    • Kabanov, A. V.; Zhu, J.; Alakhov, V. "Pluronic block copolymers for gene delivery", Adv. Genet. 2005, 53, 231-261.
    • (2005) Adv. Genet. , vol.53 , pp. 231-261
    • Kabanov, A.V.1    Zhu, J.2    Alakhov, V.3
  • 101
    • 2942632966 scopus 로고    scopus 로고
    • PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles
    • Mishra, S.; Webster, P.; Davis, M. E. "PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles", Eur. J. Cell Biol. 2004, 83, 97-111.
    • (2004) Eur. J. Cell Biol. , vol.83 , pp. 97-111
    • Mishra, S.1    Webster, P.2    Davis, M.E.3
  • 102
    • 0033852766 scopus 로고    scopus 로고
    • Improvement of receptor-mediated gene delivery to HepG2 cells using an amphiphilic gelling agent
    • Cho, C. W.; Cho, Y. S.; Lee, H. K.; Yeom, Y. I.; Park, S. N.; Yoon, D. Y. "Improvement of receptor-mediated gene delivery to HepG2 cells using an amphiphilic gelling agent", Biotechnol. Appl. Biochem. 2000, 32, 21-26.
    • (2000) Biotechnol. Appl. Biochem. , vol.32 , pp. 21-26
    • Cho, C.W.1    Cho, Y.S.2    Lee, H.K.3    Yeom, Y.I.4    Park, S.N.5    Yoon, D.Y.6
  • 103
    • 0037148596 scopus 로고    scopus 로고
    • Pluronic block copolymers: Novel functional molecules for gene therapy
    • Kabanov, A. V.; Lemieux, P.; Vinogradov, S.; Alakhov, V. "Pluronic block copolymers: novel functional molecules for gene therapy", Adv. Drug Deliv. Rev. 2002, 54, 223-233.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 223-233
    • Kabanov, A.V.1    Lemieux, P.2    Vinogradov, S.3    Alakhov, V.4
  • 105
    • 0036736888 scopus 로고    scopus 로고
    • Design and formulation of polyplexes based on Pluronic-polyethyleneimine conjugates for gene transfer
    • Gebhart, C. L.; Sriadibhatla, S.; Vinogradov, S.; Lemieux, P.; Alkahov, V.; Kabanov, V. A. "Design and formulation of polyplexes based on Pluronic-polyethyleneimine conjugates for gene transfer", Bioconjug. Chem. 2002, 13, 937-944.
    • (2002) Bioconjug. Chem. , vol.13 , pp. 937-944
    • Gebhart, C.L.1    Sriadibhatla, S.2    Vinogradov, S.3    Lemieux, P.4    Alkahov, V.5    Kabanov, V.A.6
  • 106
    • 0028989346 scopus 로고
    • Pharmacokinetics of Adenoviral vector-mediated gene delivery to vascular smooth muscle cells: Modulation by poloxamer 407 and implications for cardiovascular gene therapy
    • March, K. L.; Madison, J.; Trapnell, B. C. "Pharmacokinetics of Adenoviral vector-mediated gene delivery to vascular smooth muscle cells: modulation by poloxamer 407 and implications for cardiovascular gene therapy", Hum. Gene Ther. 1995, 6, 45-53.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 45-53
    • March, K.L.1    Madison, J.2    Trapnell, B.C.3
  • 109
    • 0032473414 scopus 로고    scopus 로고
    • Plasmid delivery to muscle: Recent advances in polymer delivery system
    • Mumper, J.; Rolland, A. P. "Plasmid delivery to muscle: recent advances in polymer delivery system", Adv. Drug Deliver. Rev. 1998, 30, 151-172.
    • (1998) Adv. Drug Deliver. Rev. , vol.30 , pp. 151-172
    • Mumper, J.1    Rolland, A.P.2
  • 110
  • 111
    • 18244366662 scopus 로고    scopus 로고
    • Tissue engineering-current challenges and expanding opportunities
    • Griffith, L. G.; Naughton, G. "Tissue engineering-current challenges and expanding opportunities", Science 2002, 295, 1009-1014.
    • (2002) Science , vol.295 , pp. 1009-1014
    • Griffith, L.G.1    Naughton, G.2
  • 112
    • 0036132692 scopus 로고    scopus 로고
    • In situ gelling and mucoadhesive polymer vehicles for controlled intranasal delivery of plasmid DNA
    • Park, J. S.; Oh, Y. K.; Yoon, H.; Kim, J. M.; Kim, C. K. "In situ gelling and mucoadhesive polymer vehicles for controlled intranasal delivery of plasmid DNA", J. Biomed. Mater. Res. 2003, 59, 144-151.
    • (2003) J. Biomed. Mater. Res. , vol.59 , pp. 144-151
    • Park, J.S.1    Oh, Y.K.2    Yoon, H.3    Kim, J.M.4    Kim, C.K.5
  • 114
    • 0032855232 scopus 로고    scopus 로고
    • Microencapsulation of DNA using poly(D, L-lactide-co-glycolide): Stability issues and release characteristics
    • Walter, E.; Moelling, K.; Pavolvich, J.; Merkle, H. P. "Microencapsulation of DNA using poly(D, L-lactide-co-glycolide): stability issues and release characteristics", J. Control. Release 1999, 61, 361-374.
    • (1999) J. Control. Release , vol.61 , pp. 361-374
    • Walter, E.1    Moelling, K.2    Pavolvich, J.3    Merkle, H.P.4
  • 115
    • 0003008343 scopus 로고    scopus 로고
    • Synthetic DNA delivery system
    • Luo, D.; Saltzman, W. M. "Synthetic DNA delivery system", Nat. Biotechnol. 2000, 18, 33-37.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 33-37
    • Luo, D.1    Saltzman, W.M.2
  • 116
    • 0036132863 scopus 로고    scopus 로고
    • Drug-releasing scaffolds fabricated from drug loaded microspheres
    • Nof, M.; Shea, L. D. "Drug-releasing scaffolds fabricated from drug loaded microspheres", J. Biomed. Mater. Res. 2002, 59, 349-356.
    • (2002) J. Biomed. Mater. Res. , vol.59 , pp. 349-356
    • Nof, M.1    Shea, L.D.2
  • 117
    • 0344515281 scopus 로고    scopus 로고
    • Gene delivery in tissue engineering: A photopolymer platform to coencapsulate cells and plasmid DNA
    • Quick, D. J.; Anseth, K. S. "Gene delivery in tissue engineering: a photopolymer platform to coencapsulate cells and plasmid DNA", Pharm. Res. 2003, 20, 1730-1737.
    • (2003) Pharm. Res. , vol.20 , pp. 1730-1737
    • Quick, D.J.1    Anseth, K.S.2
  • 118
    • 1842789875 scopus 로고    scopus 로고
    • DNA delivery from photocrosslinked PEG hydrogels: Encapsulation efficiency, release profiles, and DNA quality
    • Quick, D. J.; Anseth, K. S. "DNA delivery from photocrosslinked PEG hydrogels: encapsulation efficiency, release profiles, and DNA quality", J. Control. Release 2004, 96, 341-351.
    • (2004) J. Control. Release , vol.96 , pp. 341-351
    • Quick, D.J.1    Anseth, K.S.2
  • 119
    • 34247205938 scopus 로고    scopus 로고
    • Pulmonary vaccine delivery
    • Lu, D.; Hickey, A. J. "Pulmonary vaccine delivery", Expert Rev. Vaccines 2007, 6, 213-226.
    • (2007) Expert Rev. Vaccines , vol.6 , pp. 213-226
    • Lu, D.1    Hickey, A.J.2
  • 121
    • 84876941000 scopus 로고    scopus 로고
    • Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery
    • Todoroff, J.; Ucakar, B.; Inglese, M.; Vandermarliere, S.; Fillee, C.; Renauld, J. C.; Huygen, K.; Vanbever, R. "Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery", Eur. J. Pharm. Biopharm. 2013, 84, 40-48.
    • (2013) Eur. J. Pharm. Biopharm. , vol.84 , pp. 40-48
    • Todoroff, J.1    Ucakar, B.2    Inglese, M.3    Vandermarliere, S.4    Fillee, C.5    Renauld, J.C.6    Huygen, K.7    Vanbever, R.8
  • 123
    • 0035940089 scopus 로고    scopus 로고
    • Exploiting M cells for drug and vaccine delivery
    • Clark, M. A.; Jepson, M. A.; Hirst, B. H. "Exploiting M cells for drug and vaccine delivery", Adv. Drug Del. Rev. 2001, 50, 81-106.
    • (2001) Adv. Drug Del. Rev. , vol.50 , pp. 81-106
    • Clark, M.A.1    Jepson, M.A.2    Hirst, B.H.3
  • 124
    • 0036119653 scopus 로고    scopus 로고
    • Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers
    • Perez, C.; Castellanos, I. J.; Costantino, H. R.; Al-Azzam, W.; Griebenow, K. "Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers", J. Pharm. Pharmacol. 2002, 54, 301-313.
    • (2002) J. Pharm. Pharmacol. , vol.54 , pp. 301-313
    • Perez, C.1    Castellanos, I.J.2    Costantino, H.R.3    Al-Azzam, W.4    Griebenow, K.5
  • 125
    • 33845914772 scopus 로고    scopus 로고
    • The performance of nanocarriers for transmucosal drug delivery
    • Csaba, N.; Garcia-Fuentes, M.; Alonso, M. J. "The performance of nanocarriers for transmucosal drug delivery", Expert Opin. Drug Deliv. 2006, 3, 463-478.
    • (2006) Expert Opin. Drug Deliv. , vol.3 , pp. 463-478
    • Csaba, N.1    Garcia-Fuentes, M.2    Alonso, M.J.3
  • 127
    • 0036156113 scopus 로고    scopus 로고
    • Role of the dermonecrotic toxin of Bordetella bronchiseptica in the pathogenesis of respiratory disease in swine
    • Brockmeier, S. L.; Register, K. B.; Magyar, T.; Lax, A. J.; Pullinger, G. D.; Kunkle, R. A. "Role of the dermonecrotic toxin of Bordetella bronchiseptica in the pathogenesis of respiratory disease in swine", Infect. Immun. 2002, 70, 481-490.
    • (2002) Infect. Immun. , vol.70 , pp. 481-490
    • Brockmeier, S.L.1    Register, K.B.2    Magyar, T.3    Lax, A.J.4    Pullinger, G.D.5    Kunkle, R.A.6
  • 128
    • 34248324878 scopus 로고    scopus 로고
    • Pluronic R® F127 enhances the effect as an adjuvant of chitosan microspheres in the intranasal delivery of Bordetella bronchiseptica antigens containing dermonecrotoxin
    • Kang, M. L.; Jiang, H. L.; Kang, S. G.; Guo, D. D.; Lee, D. Y.; Cho, C. S.; Yoo, H. S. "Pluronic R® F127 enhances the effect as an adjuvant of chitosan microspheres in the intranasal delivery of Bordetella bronchiseptica antigens containing dermonecrotoxin", Vaccine 2007, 25, 4602-4610.
    • (2007) Vaccine , vol.25 , pp. 4602-4610
    • Kang, M.L.1    Jiang, H.L.2    Kang, S.G.3    Guo, D.D.4    Lee, D.Y.5    Cho, C.S.6    Yoo, H.S.7
  • 131
    • 0346392123 scopus 로고    scopus 로고
    • Pluronic gels for nasal delivery of Vitamin B12. Part I: Preformulation study
    • Pisal, S. S.; Paradkar, A. R.; Mahadik, K. R.; Kadam, S. S. "Pluronic gels for nasal delivery of Vitamin B12. Part I: Preformulation study", Int. J. Pharm. 2004, 270, 37-45.
    • (2004) Int. J. Pharm. , vol.270 , pp. 37-45
    • Pisal, S.S.1    Paradkar, A.R.2    Mahadik, K.R.3    Kadam, S.S.4
  • 132
    • 0034602597 scopus 로고    scopus 로고
    • Carbopol/pluronic phase change solutions for ophthalmic drug delivery
    • Lin, H. R.; Sung, K. C. "Carbopol/pluronic phase change solutions for ophthalmic drug delivery", J. Control. Release 2000, 69, 379-388.
    • (2000) J. Control. Release , vol.69 , pp. 379-388
    • Lin, H.R.1    Sung, K.C.2
  • 133
    • 34248632529 scopus 로고    scopus 로고
    • Formulation and in vitro characterization of an in situ gelable, photopolymerizable Pluronic hydrogel suitable for injection
    • Lee, S. Y.; Tae, G. "Formulation and in vitro characterization of an in situ gelable, photopolymerizable Pluronic hydrogel suitable for injection", J. Control. Release 2007, 119, 313-319.
    • (2007) J. Control. Release , vol.119 , pp. 313-319
    • Lee, S.Y.1    Tae, G.2
  • 134
    • 35048853961 scopus 로고    scopus 로고
    • Thermal gellation and photo-polymerization of di-acrylated Pluronic F 127
    • Lee, S. Y.; Tae, G.; Kim, Y. H. "Thermal gellation and photo-polymerization of di-acrylated Pluronic F 127", J. Biomater. Sci. Polym. Ed. 2007, 18, 1335-1353.
    • (2007) J. Biomater. Sci. Polym. Ed. , vol.18 , pp. 1335-1353
    • Lee, S.Y.1    Tae, G.2    Kim, Y.H.3
  • 137
    • 28744454127 scopus 로고    scopus 로고
    • PEO-PPO-PEO-based poly(ether ester urethane)s as degradable reverse thermo-responsive multiblock copolymers
    • Cohn, D.; Lando, G.; Sosnik, A.; Garty, S.; Levi, A. "PEO-PPO-PEO- based poly(ether ester urethane)s as degradable reverse thermo-responsive multiblock copolymers", Biomaterials 2006, 27, 1718-1727.
    • (2006) Biomaterials , vol.27 , pp. 1718-1727
    • Cohn, D.1    Lando, G.2    Sosnik, A.3    Garty, S.4    Levi, A.5
  • 138
    • 67349219709 scopus 로고    scopus 로고
    • Effect of carrageenan on poloxamer based in situ gel for vaginal use: Improved in vitro and in vivo sustained release properties
    • Liu, Y.; Zhu, Y. Y.; Wei, G.; Lu, W. Y. "Effect of carrageenan on poloxamer based in situ gel for vaginal use: Improved in vitro and in vivo sustained release properties", Eur. J. Pharm. Sci. 2009, 37, 306-312.
    • (2009) Eur. J. Pharm. Sci. , vol.37 , pp. 306-312
    • Liu, Y.1    Zhu, Y.Y.2    Wei, G.3    Lu, W.Y.4


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