Absorption of insulin from Pluronic F-127 gels following subcutaneous administration in rats

International Journal of Pharmaceutics

Volumn 184, Issue 2, 1999, Pages 189-198

  Barichello, Jose Mario ^a   Morishita, Mariko ^a   Takayama, Kozo ^a   Nagai, Tsuneji ^a  

^a Hoshi U   (Japan)

Author keywords

Hypoglycemic effect; Insulin; Pluronic F 127 gels; Polylactic co glycolic acid nanoparticles; Subcutaneous absorption; Sustained release

Indexed keywords

ANTIDIABETIC AGENT; INSULIN ZINC SUSPENSION; POLOXAMER; POLYGLACTIN;

ARTICLE; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; GEL; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; PARTICLE SIZE; PRIORITY JOURNAL;

ANIMALS; BLOOD GLUCOSE; EXCIPIENTS; GELS; HYPOGLYCEMIC AGENTS; INJECTIONS, SUBCUTANEOUS; INSULIN; LACTIC ACID; MALE; MICROSPHERES; POLOXAMER; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, WISTAR; SKIN ABSORPTION; SOLUTIONS;

EID: 0033016761     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00119-2     Document Type: Article

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