Transdermal delivery of insulin from poloxamer gel: Ex vivo and in vivo skin permeation studies in rat using iontophoresis and chemical enhancers

Journal of Controlled Release

Volumn 89, Issue 1, 2003, Pages 127-140

  Pillai, Omathanu ^a   Panchagnula, Ramesh ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Combination strategy; Linoleic acid; Menthone; PK PD relationship; Plasma glucose levels; Plasma insulin concentration; Poloxamer 407 gel

Indexed keywords

INSULIN; MOLECULAR WEIGHT; SKIN;

DELIVERY SYSTEMS;

GELS;

5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; GLUCOSE; INSULIN; LINOLEIC ACID; POLOXAMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG STABILITY; FEMALE; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; IONTOPHORESIS; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN PENETRATION; STREPTOZOCIN DIABETES;

EID: 0037437032     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00094-4     Document Type: Article

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