Investigation on recombinant hirudin via oral route

Peptides

Volumn 27, Issue 4, 2006, Pages 836-840

  Cen, Xiaodong ^a   Ni, Jianquan ^a   Tan, Taochao ^a   Liu, Xia ^a   Li, Changling ^a   Chen, Jiepeng ^b   Huang, Yixiu ^a   Zhu, Shenggeng ^a   Bi, Qun ^a  

^a PEKING UNIVERSITY   (China)

^b Strand Biotechnology Institute of Research   (China)

Author keywords

Absorption; Anticoagulant; Antithrombin; Bioavailability; Recombinant HV2 K47

Indexed keywords

ANTICOAGULANT AGENT; RECOMBINANT HIRUDIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD CLOTTING TIME; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG STABILITY; DUODENUM; ELECTROPHORESIS; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; STORAGE;

ADMINISTRATION, ORAL; ANIMALS; ANTICOAGULANTS; BLOOD COAGULATION; DRUG STABILITY; DUODENUM; HIRUDINS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MALE; MICE; RATS; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 33645380133     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2005.08.015     Document Type: Article

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