Pluronic gels for nasal delivery of Vitamin B12. Part I: Preformulation study

International Journal of Pharmaceutics

Volumn 270, Issue 1-2, 2004, Pages 37-45

  Pisal, Sambhaji S ^a   Paradkar, Anant R ^a   Mahadik, Kakasaheb R ^a   Kadam, Shivajirao S ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

Additives; Gelation and gel melting; Nasal; Poloxamer gel; Vitamin B12

Indexed keywords

BENZALKONIUM CHLORIDE; CYANOCOBALAMIN; DRUG ADDITIVE; MACROGOL; POLOXAMER; SORBITOL;

ALGORITHM; AQUEOUS SOLUTION; ARTICLE; COLD TREATMENT; DRUG DELIVERY SYSTEM; ENTHALPY; GELATION; MELTING POINT; OSMOLALITY; PHASE TRANSITION; PREFORMULATION; PRIORITY JOURNAL; THERMODYNAMICS;

EID: 0346392123     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2003.10.005     Document Type: Article

References (36)

1. BASF Wyandotte, 1997. Pluronic Surfactants, Product Brochure. BASF Corporation, Mount Olive, New Jersey.
2. Bjork E., Edman P. Degradable starch microspheres as a nasal delivery systems for insulin. Int. J. Pharm. 47:1988;233-238.
3. Brown W., Schillen K. Micelle and gel formation in a Pluronic triblock co-polymer in water: dynamic and static light scattering and oscillatory shear measurements. J. Phys. Chem. 95:1991;1850-1858.
4. Chien, Y.W., 1985. Nasal drug delivery. In: Chein, W. (Ed.), Novel Drug Delivery Systems, 2nd ed. Marcel Dekker, pp. 189-195.
5. Collectt J.H., Davies M.C. Effect of batch variability on molecular properties and in-vivo release characteristics of pluronic PF 127 gels. J. Pharm. Pharmacol. 36:1984;52.
6. 12. J. Lab. Clin. Med. 38:1951;84-87.
7. Desai S.D., Blanchard J. In vitro evaluation of Pluroinc F127-based controlled release ocular delivery systems for pilocarpine. J. Pharm. Sci. 87:1998;226-230.
8. Eldridge J.E., Ferry J.D. Studies of cross-linking process in gelatin gels. III. Dependence of melting point on concentration and molecular weight. J. Phys. Chem. 58:1954;975-992.
9. Gilbert J.C., Richardson J.L., Martyn C.D., Palin K.J. The effect of solutes and polymers on the gelation properties of pluronic -F127 solutions for controlled drug delivery. J. Control. Release. 5:1987;113-118.
10. Hussain A., Kimura R., Huang C.H., Mustafa R. Nasal absorption of ergotamine tartrate in rats. Int. J. Pharm. 21:1984;289-293.
11. Illum L., Critchley H., Davis S.S. Nasal administration of gentamicin using novel microsphere delivery system. Int. J. Pharm. 46:1988;261-265.
12. Iwanaga K., Kakemi M., Kimura T. Usefulness of liposomes as an intranasal dosage formulation for topical drug application. Biol. Pharm. Bull. 23:2000;323-326.
13. Katakam M., Ravis W.R., Banga A.K. Controlled release of human growth hormone in rats following parenteral administration of poloxamer gels. J. Control. Release. 49:1997a;21-26.
14. Kibbe, A.H., 2000. Polyethylene glycol. In: Handbook of Pharmaceutical Excipients, 3rd ed. American Pharmaceutical Association and Pharmaceutical Press, Washington, pp. 33-35.
15. Lien E.J., Perrin J.H. Effect of chain length on critical micelle formation and protein binding of quaternary ammonium compounds. J. Med. Chem. 19:1976;849-850.
16. Miller S.C., Donavan M.D. Effect of poloxamer 407 gels on the miotic activity of pilocarpine nitrate in rabbits. Int. J. Pharm. 12:1982;147-152.
17. Miller S.C., Drabik B.R. Rheological properties of poloxamer vehicles. Int. J. Pharm. 18:1984;269-276.
18. 12 in pernicious anemia. Arch. Intern. Med. 93:1954;219-221.
19. Morikawa K., Okada F., Hosokawa M., Kobayashi H. Enhancement of therapeutic effects of recombinant interleukin-2 on a transplantable rat fibrosarcoma by the use of a sustained release vehicle. Pluronic Gel. Cancer Res. 47:1987;37-41.
20. Mortensen K., Talman Y. The micelle formation and gelation of P85 using small angle neutron scattering. Macromolecules. 28:1995;8829-8832.
21. Pandit N.K., Kisaka J. Loss of gelation ability of Pluronic F127 in the presence of some salts. Int. J. Pharm. 145:1996;129-136.
22. Pec E.A., Wout Z.G., Johnston T.P. Biological activity of urease formulated in poloxamer 407 after intraperitonieal injection in the rat. J. Pharm. Sci. 81:1992;626-630.
23. Prasad K.N., Luong T.T., Florence A.T. Surface activity and association of ABA polyoxyethylene-polyoxypropylene block copolymers in aqueous solution. J. Colloid Interface Sci. 69:1979;225-233.
24. Prudhomme R.K., Guangwei Wu., Schneidev D.K. Structure and rheology studies of poly (oxyethylene-oxypropylene-oxyethylene) aqueous solution. Langmuir. 12:1996;4651-4659.
25. Rassing J., Attwood D. Ultrasonic velocity and light-scattering studies on the polyoxyethylene-polyoxypropylene copolymer Pluronic F127 in aqueous solution. Int. J. Pharm. 13:1983;47-55.
26. Rassing J., Mckanna W.P., Bandopadhyay S. Ultrasonic and 13-C NMR studies on gel formation in aqueous solution of the ABA block polymer Pluronic F127m. J. Mol. Liquids. 27:1984;165-178.
27. Rubinstein A. Intranasal administration of gentamicin in human subjects. Antimicrob. Agents Chemother. 23:1983;778-781.
28. Schmolka I.R. Artificial skin I. Preparation and properties and properties of pluronic F-127 gels for the treatment of burns. J. Biomed. Mater. Res. 6:1972;571-582.
29. Schmolka, I.R., 1991. Poloxamers in the pharmaceutical industry. In: Tarcha, P.J. (Eds.), Polymers for Controlled Drug Delivery. CRC Press, Boca Raton, pp. 189-214.
30. Stratton L.P., Dong A., Manning M.C., Carpenter J.F. Drug delivery matrix containing native protein precipitate suspended in a poloxamer gel. J. Pharm. Sci. 86:1997;1006-1010.
31. Suh H., Jun H.W., Dzimianski M.T. Pharmacokinetic and local tissue deposition studies of naproxen following topical and systemic administration in dogs and rats. Biopharm. Drug Dispos. 18:1997;623-633.
32. Tung I.C. Rheological behavior of poloxamer 407 aqueous solutions during sol-gel and dehydration process. Int. J. Pharm. 107:1994;85-90.
33. Vadnere M., Amidon G., Haslam J.L. Thermodynamic studies on the gel-sol transition of some pluronic polyols. Int. J. Pharm. 22:1984;207-218.
34. Vyas S.P., Talwar N., Jain N.K. An erythrocyte based bioadhesive system for nasal delivery of propranolol. J. Control. Release. 23:1993;231-237.
35. Wang P.L., Johnston T.P. Sustain release interleukin-2 following intramuscular injection in rats. Int. J. Pharm. 113:1995;73-81.
36. Youg C.S., Choi Q.-Z., Quan J.-D., Choi H.-G. Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive force of poloxamer gels containing diclofenac sodium. Int. J. Pharm. 226:2001;195-207.