Sustained release of plasmid DNA using lipid microtubules and agarose hydrogel

Journal of Controlled Release

Volumn 88, Issue 2, 2003, Pages 321-331

  Meilander, Nancy J ^a   Pasumarthy, Murali K ^b   Kowalczyk, Tomasz H ^b   Cooper, Mark J ^b   Bellamkonda, Ravi V ^a  

^a Case Western Reserve University   (United States)

^b University West   (United States)

Author keywords

Compacted DNA; Gene therapy; Hydrogel; Lipid microtubule; Sustained delivery

Indexed keywords

AGAROSE; LIPID; MACROGOL; PLASMID DNA; POLYLYSINE;

ARTICLE; DNA TRANSFECTION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; ELECTRON MICROSCOPY; GENE EXPRESSION; GENE THERAPY; HYDROGEL; MICROTUBULE; PRIORITY JOURNAL; SEDIMENTATION; SUSTAINED DRUG RELEASE;

EID: 0037423773     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00007-5     Document Type: Article

References (36)

1. Shea L.D., Smiley E., Bonadio J., Mooney D.J. DNA delivery from polymer matrices for tissue engineering. Nat. Biotechnol. 17:(6):1999;551-554.
2. Chandler L.A., Gu D.L., Ma C., Gonzalez A.M., Doukas J., Nguyen T., Pierce G.F., Phillips M.L. Matrix-enabled gene transfer for cutaneous wound repair. Wound Repair Regen. 8:(6):2000;473-479.
3. Bonadio J., Smiley E., Patil P., Goldstein S. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration. Nat. Med. 5:(7):1999;753-759.
4. Fang J., Zhu Y.Y., Smiley E., Bonadio J., Rouleau J.P., Goldstein S.A., McCauley L.K., Davidson B.L., Roessler B.J. Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. Proc. Natl. Acad. Sci. USA. 93:(12):1996;5753-5758.
5. Wang D., Robinson D.R., Kwon G.S., Samuel J. Encapsulation of plasmid DNA in biodegradable poly(DL-lactic-co-glycolic acid) microspheres as a novel approach for immunogene delivery. J. Control. Release. 57:(1):1999;9-18.
6. Walter E., Moelling K., Pavlovic J., Merkle H.P. Microencapsulation of DNA using poly(DL-lactide-co-glycolide): stability issues and release characteristics. J. Control. Release. 61:(3):1999;361-374.
7. Jones D.H., Clegg J.C., Farrar G.H. Oral delivery of micro-encapsulated DNA vaccines. Dev. Biol. Stand. 92:1998;149-155.
8. Hsu Y.Y., Hao T., Hedley M.L. Comparison of process parameters for microencapsulation of plasmid DNA in poly(DL-lactic-co-glycolic) acid microspheres. J. Drug Target. 7:(4):1999;313-323.
9. Ismail F.A., Napaporn J., Hughes J.A., Brazeau G.A. In situ gel formulations for gene delivery: release and myotoxicity studies. Pharm. Dev. Technol. 5:(3):2000;391-397.
10. Aggarwal N., HogenEsch H., Guo P., North A., Suckow M., Mittal S.K. Biodegradable alginate microspheres as a delivery system for naked DNA. Can. J. Vet. Res. 63:(2):1999;148-152.
11. Luo D., Woodrow-Mumford K., Belcheva N., Saltzman W.M. Controlled DNA delivery systems. Pharm. Res. 16:(8):1999;1300-1308.
12. Jong Y.S., Jacob J.S., Yip K.-P., Gardner G., Seitelman E., Whitney M., Montgomery S., Mathiowitz E. Controlled release of plasmid DNA. J. Control. Release. 47:1997;123-134.
13. Fukunaka Y., Iwanaga K., Morimoto K., Kakemi M., Tabata Y. Controlled release of plasmid DNA from cationized gelatin hydrogels based on hydrogel degradation. J. Control. Release. 80:(1-3):2002;333-343.
14. Capan Y., Woo B.H., Gebrekidan S., Ahmed S., DeLuca P.P. Preparation and characterization of poly (DL-lactide-co-glycolide) microspheres for controlled release of poly(L-lysine) complexed plasmid DNA. Pharm. Res. 16:(4):1999;509-513.
15. Fu K., Pack D.W., Klibanov A.M., Langer R. Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres. Pharm. Res. 17:(1):2000;100-106.
16. Ando S., Putnam D., Pack D.W., Langer R. PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization. J. Pharm. Sci. 88:(1):1999;126-130.
17. Wang N., Wu X.S. Preparation and characterization of agarose hydrogel nanoparticles for protein and peptide drug delivery. Pharm. Dev. Technol. 2:(2):1997;135-142.
18. Soparkar C.N., Wong J.F., Patrinely J.R., Appling D. Growth factors embedded in an agarose matrix enhance the rate of porous polyethylene implant biointegration. Ophthalmic Plast. Reconstr. Surg. 16:(5):2000;341-346.
19. Labrador R.O., Buti M., Navarro X. Peripheral nerve repair: role of agarose matrix density on functional recovery. Neuroreport. 6:(15):1995;2022-2026.
20. Iwata H., Kobayashi K., Takagi T., Oka T., Yang H., Amemiya H., Tsuji T., Ito F. Feasibility of agarose microbeads with xenogeneic islets as a bioartificial pancreas. J. Biomed. Mater. Res. 28:(9):1994;1003-1011.
21. Meilander N.J., Yu X., Ziats N.P., Bellamkonda R.V. Lipid-based microtubular drug delivery vehicles. J. Control. Release. 71:(1):2001;141-152.
22. Spargo B.J., Cliff R.O., Rollwagen F.M., Rudolph A.S. Controlled release of transforming growth factor-beta from lipid-based microcylinders. J. Microencaps. 12:(3):1995;247-254.
23. Yu X., Dillon G.P., Bellamkonda R.B. A laminin and nerve growth factor-laden three-dimensional scaffold for enhanced neurite extension. Tissue Eng. 5:(4):1999;291-304.
24. Gedeon C., Ziady A., Miller T.J., Payne J.M., Kowalczyk T.H., Pasumarthy M.K., Davis P.B., Moen R.C., Cooper M.J. High-level expression of compacted DNA complexes following intratracheal administration. Mol. Ther. 1:(5):2000;S78.
25. Kerschmann R., Ziady A., Gedeon C., Muhammad O., Kowalczyk T., Pasumarthy M., Hyatt S., Moen R., Cooper M. 3-Dimensional imaging of EGFP expression in mouse lung using compacted DNA nanoparticles. Mol. Ther. 3:(5):2001;S404.
26. Schnur J.M. Lipid tubules: a paradigm for molecularly engineered structures. Science. 262:1993;1669-1676.
27. Kowalczyk T.H., Pasumarthy M.K., Gedeon C., Moen R.C., Cooper M.J. Light scattering by compacted DNA predicts its serum stability. Mol. Ther. 1:(5):2000;S120.
28. Goodnough L.T., Kleinhenz M.E., Goldsmith G.H. Jr., Ziats N.P., Robertson A.L. Jr. Bovine aortic endothelial cells elaborate an inhibitor of the generation of lipopolysaccharide-stimulated human blood monocyte procoagulant activity. J. Clin. Invest. 74:(1):1984;75-81.
29. Dillon G.P., Yu X., Sridharan A., Ranieri J.P., Bellamkonda R.V. The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold. J. Biomater. Sci. Polym. Ed. 9:(10):1998;1049-1069.
30. Yager P., Schoen P.E. Formation of tubules by a polymerizable surfactant. Mol. Cryst. Liq. Cryst. 106:1984;371-381.
31. Ziady A.G., Payne J.M., Oette S., Gideon C., Muhammad O., Kowalczyk T.H., Hyatt S.L., Pasumarthy M.K., van Heeckren C., Poleman J., Seng J.E., Cooper M.J., Moen R.C., Davis P.B. Lack of typical inflammatory responses to CpG sequences following intrapulmonary administration of plasmid DNA compacted with PEG-substituted polylysine. Mol. Ther. 5:(5):2002;S436.
32. Liu G., Li D., Pasumarthy M., Kowalczyk T., Gedeon C., Hyatt S., Payne J., Miller T., Brunovskis P., Moen R., Hanson R., Cooper M. Nanoparticles of compacted DNA transfect post-mitotic cells. Mol. Ther. 3:(5):2001;S14.
33. Cohen H., Levy R.J., Gao J., Fishbein I., Kousaev V., Sosnowski S., Slomkowski S., Golomb G. Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles. Gene Ther. 7:(22):2000;1896-1905.
34. Tinsley-Bown A.M., Fretwell R., Dowsett A.B., Davis S.L., Farrar G.H. Formulation of poly(D,L-lactic-co-glycolic acid) microparticles for rapid plasmid DNA delivery. J. Control. Release. 66:(2-3):2000;229-241.
35. Singh M., Briones M., Ott G., O'Hagan D. Cationic microparticles: a potent delivery system for DNA vaccines. Proc. Natl. Acad. Sci. USA. 97:(2):2000;811-816.
36. Cooper M.J. Noninfectious gene transfer and expression systems for cancer gene therapy. Lattime E.C., Gerson S.L. 2nd Edition Gene Therapy of Cancer. 2002;31-52 Academic Press, New York.