The chemotherapeutic potential of PEG-b-PLGA copolymer micelles that combine chloroquine as autophagy inhibitor and docetaxel as an anti-cancer drug

Biomaterials

Volumn 35, Issue 33, 2014, Pages 9144-9154

  Zhang, Xudong ^a   Zeng, Xiaowei ^a   Liang, Xin ^b   Yang, Ying ^a   Li, Xiaoming ^a   Chen, Hongbo ^a   Huang, Laiqiang ^a   Mei, Lin ^a   Feng, Si Shen ^a,c,d  

^a TSINGHUA UNIVERSITY   (China)

^b GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Biodegradable polymers; Cancer nanotechnology; Chemotherapeutic engineering; Intracellular autophagy; Nanomedicine; Pharmaceutical nanotechnology

Indexed keywords

BIODEGRADABLE POLYMERS; CELLS; COPOLYMERS; DIALYSIS MEMBRANES; DRUG DELIVERY; DRUG PRODUCTS; LOADING; MEDICAL NANOTECHNOLOGY; NANOTECHNOLOGY; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

AUTOPHAGY; CANCER NANOTECHNOLOGY; CHEMOTHERAPEUTIC ENGINEERING; CLINICAL APPLICATION; CONFOCAL LASER SCANNING MICROSCOPY; DRUG ENCAPSULATION EFFICIENCY; EFFICIENT DRUG DELIVERY; NARROW SIZE DISTRIBUTIONS;

MICELLES;

ANTINEOPLASTIC AGENT; CHLOROQUINE; COPOLYMER; DOCETAXEL; MACROGOL; POLYGLACTIN; MACROGOL DERIVATIVE; MICELLE; NANOPARTICLE; POLY(LACTIC-GLYCOLIC ACID)-POLY(ETHYLENEGLYCOL) COPOLYMER; TAXOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG FORMULATION; ENCAPSULATION; HUMAN; HUMAN CELL; MCF 7 CELL LINE; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ZETA POTENTIAL; ANIMAL; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; FEMALE; NANOMEDICINE; PARTICLE SIZE; PROCEDURES; SCID MOUSE; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CELL LINE, TUMOR; CHLOROQUINE; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MCF-7 CELLS; MICE; MICE, SCID; MICELLES; NANOMEDICINE; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; TAXOIDS;

EID: 84906789123     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.07.028     Document Type: Article

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