Why sick cells produce tumors: The protective role of autophagy

Autophagy

Volumn 3, Issue 5, 2007, Pages 502-504

  Mathew, Robin ^a,b   White, Eileen ^a,b,c,d  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

atg5; Autophagy; Beclin1; Cancer; Chromosomal instability; DNA damage; Metabolism

Indexed keywords

ADENOSINE TRIPHOSPHATE; AUTOPHAGY INHIBITOR; CHLOROQUINE; DNA; DOUBLE STRANDED DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ATG5 GENE; AUTOPHAGY; BECLIN 1 GENE; CARCINOGENESIS; CELL DAMAGE; CELL FUNCTION; CELL PROTECTION; CELL SURVIVAL; CHEMOPROPHYLAXIS; CHROMOSOMAL GAIN; CHROMOSOMAL INSTABILITY; CHROMOSOME LOSS; CONTROLLED STUDY; DNA DAMAGE; GENE; GENE DELETION; HOMEOSTASIS; METABOLIC STRESS; MOUSE; MUTATION RATE; NERVE CELL DEGENERATION; NONHUMAN; PROTEIN AGGREGATION; REVIEW; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR SUPPRESSOR GENE; UBIQUITINATION;

EID: 34548096175     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.4605     Document Type: Review

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