The molecular mechanism of eukaryotic elongation factor 2 kinase activation

Journal of Biological Chemistry

Volumn 289, Issue 34, 2014, Pages 23901-23916

  Tavares, Clint D J ^a   Ferguson, Scarlett B ^a   Giles, David H ^a   Wang, Qiantao ^a,b   Wellmann, Rebecca M ^a   O'Brien, John P ^c   Warthaka, Mangalika ^a   Brodbelt, Jennifer S ^c   Ren, Pengyu ^b   Dalby, Kevin N ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b The University of Texas at Austin   (United States)

^c University of Texas at Austin   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CAMS; CHEMICAL ACTIVATION; CONFORMATIONS; ELONGATION; ENZYMES; MOLECULAR INTERACTIONS; PHOSPHORYLATION;

ALLOSTERIC MECHANISMS; AUTOPHOSPHORYLATION; COMPLEX REGULATION; CONFORMATIONAL TRANSITIONS; MOLECULAR MECHANISM; PEPTIDE SUBSTRATES; PRECISE INTEGRATION; PROTEIN TRANSLATION;

CALMODULIN;

CALMODULIN; ELONGATION FACTOR; EUKARYOTIC ELONGATION FACTOR 2 KINASE; THREONINE; UNCLASSIFIED DRUG; CALCIUM; EEF2K PROTEIN, HUMAN; ELONGATION FACTOR 2 KINASE;

ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME SUBSTRATE; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN SYNTHESIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; TUMOR CELL LINE;

AMINO ACID SEQUENCE; CALCIUM; CALMODULIN; CELL LINE, TUMOR; ELONGATION FACTOR 2 KINASE; ENZYME ACTIVATION; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; THREONINE;

EID: 84906536736     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.577148     Document Type: Article

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