F-box proteins elongate translation during stress recovery

Science Signaling

Volumn 5, Issue 227, 2012, Pages

  Meloche, Sylvain ^a,b   Roux, Philippe P ^a,b  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; CULLIN; ELONGATION FACTOR 2 KINASE; F BOX PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 4E BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN P53; S PHASE KINASE ASSOCIATED PROTEIN; UBIQUITIN PROTEIN LIGASE E3;

ATAXIA TELANGIECTASIA; AUTOPHOSPHORYLATION; CANCER CELL; CELL STRESS; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GENOTOXICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REVIEW; RNA TRANSLATION; SIGNAL TRANSDUCTION; STRESS; ARTICLE; GENETICS; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

DNA DAMAGE; F-BOX PROTEINS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; STRESS, PHYSIOLOGICAL;

EID: 84862117689     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2003163     Document Type: Review

References (20)

1. F. Buttgereit, M. D. Brand, A hierarchy of ATP-consuming processes in mammalian cells. Biochem. J. 312, 163-167 (1995).
2. N. Sonenberg, A. G. Hinnebusch, Regulation of translation initiation in eukaryotes: Mechanisms and biological targets. Cell 136, 731-745 (2009).
3. F. Kruiswijk, L. Yuniati, R. Magliozzi, T. Y. Low, R. Lim, R. Bolder, S. Mohammed, C. G. Proud, A. J. R. Heck, M. Pagano, D. Guardavaccaro, Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress. Sci. Signal. 5, ra40 (2012).
4. X. M. Ma, J. Blenis, Molecular mechanisms of mTOR-mediated translational control. Nat. Rev. Mol. Cell Biol. 10, 307-318 (2009).
5. E. Caron, S. Ghosh, Y. Matsuoka, D. Ashton- Beaucage, M. Therrien, S. Lemieux, C. Perreault, P. P. Roux, H. Kitano, A comprehensive map of the mTOR signaling network. Mol. Syst. Biol. 6, 453 (2010).
6. G. Kaul, G. Pattan, T. Rafeequi, Eukaryotic elongation factor-2 (eEF2): Its regulation and peptide chain elongation. Cell Biochem. Funct. 29, 227-234 (2011).
7. M. M. Mihaylova, R. J. Shaw, The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat. Cell Biol. 13, 1016-1023 (2011).
8. S. Braunstein, M. L. Badura, Q. Xi, S. C. Formenti, R. J. Schneider, Regulation of protein synthesis by ionizing radiation. Mol. Cell. Biol. 29, 5645-5656 (2009).
9. L. W. Ellisen, K. D. Ramsayer, C. M. Johannessen, A. Yang, H. Beppu, K. Minda, J. D. Oliner, F. McKeon, D. A. Haber, REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. Mol. Cell 10, 995-1005 (2002).
10. Z. Feng, H. Zhang, A. J. Levine, S. Jin, The coordinate regulation of the p53 and mTOR pathways in cells. Proc. Natl. Acad. Sci. U.S.A. 102, 8204-8209 (2005).
11. V. Stambolic, D. MacPherson, D. Sas, Y. Lin, B. Snow, Y. Jang, S. Benchimol, T. W. Mak, Regulation of PTEN transcription by p53. Mol. Cell 8, 317-325 (2001).
12. A. V. Budanov, M. Karin, p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell 134, 451-460 (2008).
13. H. Cam, J. B. Easton, A. High, P. J. Houghton, mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α. Mol. Cell 40, 509-520 (2010).
14. A. Alexander, S. L. Cai, J. Kim, A. Nanez, M. Sahin, K. H. MacLean, K. Inoki, K. L. Guan, J. Shen, M. D. Person, D. Kusewitt, G. B. Mills, M. B. Kastan, C. L. Walker, ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc. Natl. Acad. Sci. U.S.A. 107, 4153-4158 (2010).
15. N. V. Dorrello, A. Peschiaroli, D. Guardavaccaro, N. H. Colburn, N. E. Sherman, M. Pagano, S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 314, 467-471 (2006).
16. J. Lagirand-Cantaloube, N. Offner, A. Csibi, M. P. Leibovitch, S. Batonnet-Pichon, L. A. Tintignac, C. T. Segura, S. A. Leibovitch, The initiation factor eIF3-f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy. EMBO J. 27, 1266-1276 (2008).
17. M. Yoshida, K. Yoshida, G. Kozlov, N. S. Lim, G. De Crescenzo, Z. Pang, J. J. Berlanga, A. Kahvejian, K. Gehring, S. S. Wing, N. Sonenberg, Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2. EMBO J. 25, 1934-1944 (2006).
18. S. Pyr Dit Ruys, X. Wang, E. M. Smith, G. Herinckx, N. Hussain, M. H. Rider, D. Vertommen, C. G. Proud, Identifi cation of autophosphorylation sites in eukaryotic elongation factor-2 kinase. Biochem. J. 442, 681-692 (2012).
19. R. J. Kaufman, D. Scheuner, M. Schröder, X. Shen, K. Lee, C. Y. Liu, S. M. Arnold, The unfolded protein response in nutrient sensing and differentiation. Nat. Rev. Mol. Cell Biol. 3, 411-421 (2002).
20. I. R. Powley, A. Kondrashov, L. A. Young, H. C. Dobbyn, K. Hill, I. G. Cannell, M. Stoneley, Y. W. Kong, J. A. Cotes, G. C. Smith, R. Wek, C. Hayes, T. W. Gant, K. A. Spriggs, M. Bushell, A. E. Willis, Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes. Genes Dev. 23, 1207-1220 (2009).