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Volumn 367, Issue 2, 2002, Pages 525-532

Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways

Author keywords

Elongation; mRNA translation; p38; SB 203580

Indexed keywords

ENZYME INHIBITION; ENZYMES; PROTEINS; STRESSES; SUBSTRATES; TUMORS;

EID: 0037109036     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020916     Document Type: Article
Times cited : (77)

References (25)
  • 1
    • 0022369404 scopus 로고
    • Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues
    • Nairn, A. C., Bhagat, B and Palfrey, H. C. (1985) Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues. Proc. Natl. Acad. Sci. U.S.A. 82, 7939-7943
    • (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 7939-7943
    • Nairn, A.C.1    Bhagat, B.2    Palfrey, H.C.3
  • 2
    • 0024513394 scopus 로고
    • 2+/calmodulin·dependent protein kinase in rat adrenal glomerulosa cells
    • 2+/calmodulin.dependent protein kinase in rat adrenal glomerulosa cells. J. Steroid. Biochem. 32, 381-385
    • (1989) J. Steroid. Biochem. , vol.32 , pp. 381-385
    • Kigoshi, T.1    Uchida, K.2    Morimoto, S.3
  • 3
    • 0025003542 scopus 로고
    • Functional properties of phosphorylated elongation factor 2
    • Carlberg, U., Nilsson, A. and Nygard, C. (1990) Functional properties of phosphorylated elongation factor 2. Eur. J. Biochem. 191, 639-645
    • (1990) Eur. J. Biochem. , vol.191 , pp. 639-645
    • Carlberg, U.1    Nilsson, A.2    Nygard, C.3
  • 4
    • 0025868969 scopus 로고
    • Identification of the phosphorylation sites in elongation factor-2 from rabbit reticulocytes
    • Price, N. T., Redpath, N. T., Severinov, K. V., Campbell, D. G., Russell, J. M. and Proud, C. G. (1991) Identification of the phosphorylation sites in elongation factor-2 from rabbit reticulocytes. FEBS Lett. 282, 253-258
    • (1991) FEBS Lett. , vol.282 , pp. 253-258
    • Price, N.T.1    Redpath, N.T.2    Severinov, K.V.3    Campbell, D.G.4    Russell, J.M.5    Proud, C.G.6
  • 5
    • 0020567791 scopus 로고
    • Presence in many mammalian tissues of an identical major cytosolic substrate (Mr 100000) for calmodulin-dependent protein kinase
    • Palfrey, H. C. (1983) Presence in many mammalian tissues of an identical major cytosolic substrate (Mr 100000) for calmodulin-dependent protein kinase. FEBS Lett. 157, 183-190
    • (1983) FEBS Lett. , vol.157 , pp. 183-190
    • Palfrey, H.C.1
  • 6
    • 0023522187 scopus 로고
    • Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2
    • Nairn, A. C. and Palfrey, H. C. (1987) Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2. J. Biol. Chem. 262, 17299-17303
    • (1987) J. Biol. Chem. , vol.262 , pp. 17299-17303
    • Nairn, A.C.1    Palfrey, H.C.2
  • 8
    • 0023884601 scopus 로고
    • Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation
    • Ryazanov, A. G., Shestakova, E. A. and Natapov, P. G. (1988) Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation. Nature (London) 334, 170-173
    • (1988) Nature (London) , vol.334 , pp. 170-173
    • Ryazanov, A.G.1    Shestakova, E.A.2    Natapov, P.G.3
  • 9
    • 0035881737 scopus 로고    scopus 로고
    • A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta
    • Knebel, A., Morrice, N. and Cohen, P. (2001) A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta. EMBO J. 20, 4360-4369
    • (2001) EMBO J. , vol.20 , pp. 4360-4369
    • Knebel, A.1    Morrice, N.2    Cohen, P.3
  • 10
    • 10744227768 scopus 로고    scopus 로고
    • Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket
    • Gum, R. J., McLaughlin, M. M., Kumar, S., Wang, Z., Bower, M. J., Lee, J. C., Adams, J. L., Livi, G. P., Goldsmith, E. J. and Young, P. R. (1998) Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. J. Biol. Chem. 273, 15605-15610
    • (1998) J. Biol. Chem. , vol.273 , pp. 15605-15610
    • Gum, R.J.1    McLaughlin, M.M.2    Kumar, S.3    Wang, Z.4    Bower, M.J.5    Lee, J.C.6    Adams, J.L.7    Livi, G.P.8    Goldsmith, E.J.9    Young, P.R.10
  • 11
    • 0032102902 scopus 로고    scopus 로고
    • Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution
    • Eyers, P. A., Craxton, M., Morrice, N., Cohen, P. and Goedert, M. (1998) Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. Chem. Biol. 5, 321-328
    • (1998) Chem. Biol. , vol.5 , pp. 321-328
    • Eyers, P.A.1    Craxton, M.2    Morrice, N.3    Cohen, P.4    Goedert, M.5
  • 12
    • 0035881470 scopus 로고    scopus 로고
    • Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase
    • Wang, X., Li, W., Williams, M., Terada, N., Alessi, D. R. and Proud, C. G. (2001) Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J. 20, 4370-4379
    • (2001) EMBO J. , vol.20 , pp. 4370-4379
    • Wang, X.1    Li, W.2    Williams, M.3    Terada, N.4    Alessi, D.R.5    Proud, C.G.6
  • 13
    • 0027273725 scopus 로고
    • Regulation of elongation factor-2 by multisite phosphorylation
    • Redpath, N. T., Price, N. T., Severinov, K. V. and Proud, C. G. (1993) Regulation of elongation factor-2 by multisite phosphorylation. Eur. J. Biochem 213, 689-699
    • (1993) Eur. J. Biochem. , vol.213 , pp. 689-699
    • Redpath, N.T.1    Price, N.T.2    Severinov, K.V.3    Proud, C.G.4
  • 16
    • 0033565832 scopus 로고    scopus 로고
    • Role of accurate mass measurement (± 10 ppm) in protein identification strategies employing MS or MS/MS and database searching
    • Clauser, K. R., Baker, P. R. and Burlingame, A. L. (1999) Role of accurate mass measurement (± 10 ppm) in protein identification strategies employing MS or MS/MS and database searching. Anal. Chem. 71, 2871-2882
    • (1999) Anal. Chem. , vol.71 , pp. 2871-2882
    • Clauser, K.R.1    Baker, P.R.2    Burlingame, A.L.3
  • 17
    • 0026733636 scopus 로고
    • MAPKAP kinase-2: A novel protein kinase activated by mitogen-activated protein kinase
    • Stokoe, D., Campbell, D. G., Nakielny, S., Hidaka, H., Leevers, S. J., Marshall, C. and Cohen, P (1992) MAPKAP kinase-2: A novel protein kinase activated by mitogen-activated protein kinase. EMBO J. 11, 3985-3994
    • (1992) EMBO J. , vol.11 , pp. 3985-3994
    • Stokoe, D.1    Campbell, D.G.2    Nakielny, S.3    Hidaka, H.4    Leevers, S.J.5    Marshall, C.6    Cohen, P.7
  • 18
    • 0026457201 scopus 로고
    • Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins
    • Stokoe, D., Engel, K., Campbell, D. G., Cohen, P. and Gaestel, M. (1992) Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. FEBS Lett. 313, 307-313
    • (1992) FEBS Lett. , vol.313 , pp. 307-313
    • Stokoe, D.1    Engel, K.2    Campbell, D.G.3    Cohen, P.4    Gaestel, M.5
  • 19
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and hear shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
    • Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T. and Nebreda, A. R. (1994) A novel kinase cascade triggered by stress and hear shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78, 1027-1037
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3    Morange, M.4    Alonso-Llamazares, A.5    Zamanillo, D.6    Hunt, T.7    Nebreda, A.R.8
  • 20
    • 0032901378 scopus 로고    scopus 로고
    • Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the In vivo specificity of SB 203580
    • Eyers, P. A., van den Ijssel, P., Quinlan, R. A., Goedert, M. and Cohen, P. (1999) Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the In vivo specificity of SB 203580. FEBS Lett. 451, 191-196
    • (1999) FEBS Lett. , vol.451 , pp. 191-196
    • Eyers, P.A.1    Van den Ijssel, P.2    Quinlan, R.A.3    Goedert, M.4    Cohen, P.5
  • 21
    • 0029923193 scopus 로고    scopus 로고
    • Identification of mitogen-activated protein (MAP) kinase·activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase
    • McLaughlin, M. M., Kumar, S., McDonnell, P. C., Van Horn, S., Lee, J. C., Livi, G. P. and Young, P. R. (1996) Identification of mitogen-activated protein (MAP) kinase. activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase. J. Biol. Chem. 271, 8488-8492
    • (1996) J. Biol. Chem. , vol.271 , pp. 8488-8492
    • McLaughlin, M.M.1    Kumar, S.2    McDonnell, P.C.3    Van Horn, S.4    Lee, J.C.5    Livi, G.P.6    Young, P.R.7
  • 22
    • 0030565457 scopus 로고    scopus 로고
    • A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress
    • Clifton, A. D., Young, P. R. and Cohen, P. (1996) A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress. FEBS Lett. 392, 209-214
    • (1996) FEBS Lett. , vol.392 , pp. 209-214
    • Clifton, A.D.1    Young, P.R.2    Cohen, P.3
  • 24
    • 0032512546 scopus 로고    scopus 로고
    • MAPKAPK5, a novel mitogen-activated protein kinase (MAPK)-activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase
    • Ni, H., Wang, X. S., Diener, K. and Yao, Z. (1998) MAPKAPK5, a novel mitogen-activated protein kinase (MAPK)-activated protein kinase, is a substrate of the extracellular-regulated kinase (ERK) and p38 kinase. Biochem. Biophys. Res. Commun. 243, 492-496
    • (1998) Biochem. Biophys. Res. Commun. , vol.243 , pp. 492-496
    • Ni, H.1    Wang, X.S.2    Diener, K.3    Yao, Z.4
  • 25
    • 0027739284 scopus 로고
    • The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2
    • Stokoe, D., Caudwell, B., Cohen, P. T. and Cohen, P. (1993) The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2. Biochem. J. 296, 843-849
    • (1993) Biochem. J. , vol.296 , pp. 843-849
    • Stokoe, D.1    Caudwell, B.2    Cohen, P.T.3    Cohen, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.