Insights into the regulation of eukaryotic elongation factor 2 kinase and the interplay between its domains

Biochemical Journal

Volumn 442, Issue 1, 2012, Pages 105-118

  Pigott, Craig R ^a,d   Mikolajek, Halina ^b   Moore, Claire E ^b   Finn, Stephen J ^c   Phippen, Curtis W ^b   Werner, Jörn M ^b   Proud, Christopher G ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d Innovative Targeting Solutions   (Canada)

Author keywords

kinase; Calmodulin (CaM); Eukaryotic elongation factor 2 (eEF2); SEL1 domain

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CALMODULIN; ELONGATION FACTOR 2 KINASE; EUKARYOTIC ELONGATION FACTOR 2 KINASE; METAL ION; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; AUTOPHOSPHORYLATION; CALCIUM BINDING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; ELONGATION FACTOR 2 KINASE; HEK293 CELLS; HUMANS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; ZINC;

EUKARYOTA;

EID: 84856263494     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111536     Document Type: Article

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