-
1
-
-
77952810407
-
The signaling interface of the yeast multidrug transporter Pdr5 adopts a cis conformation and there are functional overlap and equivalence of the deviant and canonical Q-loop residues
-
Ananthaswamy, N., Rutledge, R., Sauna, Z.E., Dine, E., Nelson, E., Xia, D., and Golin, J. (2010). The signaling interface of the yeast multidrug transporter Pdr5 adopts a cis conformation and there are functional overlap and equivalence of the deviant and canonical Q-loop residues. Biochemistry. 49, 4440-4449.
-
(2010)
Biochemistry
, vol.49
, pp. 4440-4449
-
-
Ananthaswamy, N.1
Rutledge, R.2
Sauna, Z.E.3
Dine, E.4
Nelson, E.5
Xia, D.6
Golin, J.7
-
2
-
-
0030716391
-
The Candida albicans CDR3 gene codes for an opaque-phase ABC transporter
-
Balan, I., Alarco, A.M., and Raymond, M. (1997). The Candida albicans CDR3 gene codes for an opaque-phase ABC transporter. J. Bacteriol. 179, 7210-18.
-
(1997)
J. Bacteriol.
, vol.179
, pp. 7210-7218
-
-
Balan, I.1
Alarco, A.M.2
Raymond, M.3
-
3
-
-
0028293750
-
Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene
-
Ben-Yaacov, R., Knoller, S., Caldwell, G.A., Becker, J.M., and Koltin, Y. (1994). Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene. Antimicrob. Agents Chemother. 38, 648-652.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 648-652
-
-
Ben-Yaacov, R.1
Knoller, S.2
Caldwell, G.A.3
Becker, J.M.4
Koltin, Y.5
-
4
-
-
77955617560
-
A human-curated annotation of the Candida albicans genome
-
Braun, B.R., Vanhet, H.M., d'Enfert, C., Martchenko, M., Dungan, J., Kuo, A., Inglis, D.O., et al. (2005). A human-curated annotation of the Candida albicans genome. PLoS. Genet. 1, 36-57.
-
(2005)
PLoS. Genet.
, vol.1
, pp. 36-57
-
-
Braun, B.R.1
Vanhet, H.M.2
d'Enfert, C.3
Martchenko, M.4
Dungan, J.5
Kuo, A.6
Inglis, D.O.7
-
5
-
-
66449112829
-
Efflux-mediated antifungal drug resistance
-
Cannon, R.D., Lamping, E., Holmes, A.R., Niimi, K., Baret, P.V., Keniya, M.V., Tanabe, K., Niimi, M., Goffeau, A., and Monk, B.C. (2009) Efflux-mediated antifungal drug resistance. Clin. Microbiol. Rev. 22, 291-321.
-
(2009)
Clin. Microbiol. Rev.
, vol.22
, pp. 291-321
-
-
Cannon, R.D.1
Lamping, E.2
Holmes, A.R.3
Niimi, K.4
Baret, P.V.5
Keniya, M.V.6
Tanabe, K.7
Niimi, M.8
Goffeau, A.9
Monk, B.C.10
-
6
-
-
0021862533
-
Steroid binding protein(s) in yeasts
-
Das, M, and Datta, A. 1985. Steroid binding protein(s) in yeasts. Biochem Int. 11, 17-176.
-
(1985)
Biochem Int
, vol.11
, pp. 17-176
-
-
Das, M.1
Datta, A.2
-
7
-
-
0032524635
-
ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p
-
Decottignies, A., Grant, A.M., Nichols, J.W., De. Wet. H., McIntosh, D.B., and Goffeau, A. (1998). ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p. J. Biol. Chem. 273, 12612-22.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12612-12622
-
-
Decottignies, A.1
Grant, A.M.2
Nichols, J.W.3
De Wet, H.4
McIntosh, D.B.5
Goffeau, A.6
-
8
-
-
84872867465
-
The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance
-
Downes, M.T., Mehla, J., Ananthaswamy, N., Wakschlag, A., Lamonde, M., et al. (2013). The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance. Antimicrob Agents Chemother. 57, 1025-34.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 1025-1034
-
-
Downes, M.T.1
Mehla, J.2
Ananthaswamy, N.3
Wakschlag, A.4
Lamonde, M.5
-
9
-
-
0031905588
-
Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter
-
Egner., R., Rosenthal, F.E., Kralli, A., Sanglard, D., and Kuchler, K. (1998). Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter. Mol. Biol. Cell. 9, 523-543.
-
(1998)
Mol. Biol. Cell.
, vol.9
, pp. 523-543
-
-
Egner, R.1
Rosenthal, F.E.2
Kralli, A.3
Sanglard, D.4
Kuchler, K.5
-
10
-
-
0032487393
-
A fourth gene from the Candida albicans CDR family of ABC transporters
-
Franz, R., Michel, S., and Morschhauser, J. (1998). A fourth gene from the Candida albicans CDR family of ABC transporters. Gene. 220, 91-98.
-
(1998)
Gene
, vol.220
, pp. 91-98
-
-
Franz, R.1
Michel, S.2
Morschhauser, J.3
-
11
-
-
0031692037
-
Identification of polymorphic mutant alleles of CaMDR1, a major facilitator of Candida albicans which confers multidrug resistance, and its in vitro transcriptional activation
-
Gupta, V., Kohli, A., Krishnamurthy, S., Puri, N., Aalamgeer, S.A., Panwar, S., and Prasad, R. (1998). Identification of polymorphic mutant alleles of CaMDR1, a major facilitator of Candida albicans which confers multidrug resistance, and its in vitro transcriptional activation. Curr. Genet.34, 192-199.
-
(1998)
Curr. Genet
, vol.34
, pp. 192-199
-
-
Gupta, V.1
Kohli, A.2
Krishnamurthy, S.3
Puri, N.4
Aalamgeer, S.A.5
Panwar, S.6
Prasad, R.7
-
12
-
-
27544514993
-
Complete inventory of ABC proteins in human pathogenic yeast Candida albicans
-
Gaur, M., Choudhury, D., and Prasad, R. (2005). Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans. J. Mol. Microbiol. Biotechnol. 9, 3-15.
-
(2005)
J. Mol. Microbiol. Biotechnol.
, vol.9
, pp. 3-15
-
-
Gaur, M.1
Choudhury, D.2
Prasad, R.3
-
13
-
-
63149167412
-
MFS transportome of the human pathogenic yeast Candida albicans
-
Gaur, M., Puri, N., Manoharlal, R., Rai, V., Mukhopadhayay, G., et al. (2008). MFS transportome of the human pathogenic yeast Candida albicans. BMC Genomics. 9, 579.
-
(2008)
BMC Genomics
, vol.9
, pp. 579
-
-
Gaur, M.1
Puri, N.2
Manoharlal, R.3
Rai, V.4
Mukhopadhayay, G.5
-
14
-
-
0034050363
-
The TetA(K) tetracycline/H(+) antiporter from Staphylococcus aureus: mutagenesis and functional analysis of motif C
-
Ginn, S.L., Brown, M.H., and Skurray, R.A., (2000). The TetA(K) tetracycline/H(+) antiporter from Staphylococcus aureus: mutagenesis and functional analysis of motif C. J Bacteriol. 182, 1492-1498.
-
(2000)
J Bacteriol
, vol.182
, pp. 1492-1498
-
-
Ginn, S.L.1
Brown, M.H.2
Skurray, R.A.3
-
15
-
-
0033988629
-
Chemical specificity of the PDR5 multidrug resistance gene product of Saccharomyces cerevisiae based on studies with tri-n-alkyltin chlorides
-
Golin, J., Barkatt, A., Cronin, S., Eng, G., and May, L. (2000). Chemical specificity of the PDR5 multidrug resistance gene product of Saccharomyces cerevisiae based on studies with tri-n-alkyltin chlorides. Antimicrob. Agents. Chemother. 44, 134-138.
-
(2000)
Antimicrob. Agents. Chemother.
, vol.44
, pp. 134-138
-
-
Golin, J.1
Barkatt, A.2
Cronin, S.3
Eng, G.4
May, L.5
-
16
-
-
84855441982
-
A mutation in intracellular loop 4 affects the drug-efflux activity of the yeast multidrug resistance ABC transporter Pdr5p
-
Guo, X., Li, J., Wang, T., Liu, Z., Chen, X., et al. (2012). A mutation in intracellular loop 4 affects the drug-efflux activity of the yeast multidrug resistance ABC transporter Pdr5p. PLoS One.7, e29520.
-
(2012)
PLoS One
, vol.7
-
-
Guo, X.1
Li, J.2
Wang, T.3
Liu, Z.4
Chen, X.5
-
17
-
-
78651353957
-
The multidrug transporter Pdr5: a molecular diode
-
Gupta, R.P., Kueppers, P., Schmitt, L., and Ernst, R. (2011). The multidrug transporter Pdr5: a molecular diode. Biol. Chem. 392, 53-60.
-
(2011)
Biol. Chem.
, vol.392
, pp. 53-60
-
-
Gupta, R.P.1
Kueppers, P.2
Schmitt, L.3
Ernst, R.4
-
18
-
-
4744358624
-
The ATP switch model for ABC transporters
-
Higgins, C.F., and Linton, K.J., (2004). The ATP switch model for ABC transporters. Nat. Struct. Mol. Biol. 11, 918-926.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 918-926
-
-
Higgins, C.F.1
Linton, K.J.2
-
19
-
-
0042318833
-
Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis
-
Jha, S., Karnani, N., Dhar, S. K., Mukhopadhayay, K., Shukla, S., Saini, P., Mukhopadhayay, G., and Prasad, R. (2003). Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis Biochemistry 42, 10822-10832.
-
(2003)
Biochemistry
, vol.42
, pp. 10822-10832
-
-
Jha, S.1
Karnani, N.2
Dhar, S.K.3
Mukhopadhayay, K.4
Shukla, S.5
Saini, P.6
Mukhopadhayay, G.7
Prasad, R.8
-
20
-
-
4744371579
-
ABC multidrug transporter Cdr1p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry
-
Jha, S., Dabas, N., Karnani, N., Saini, P., and Prasad, R. (2004). ABC multidrug transporter Cdr1p of Candida albicans has divergent nucleotide-binding domains which display functional asymmetry. FEMS Yeast Research. 5, 63-72.
-
(2004)
FEMS Yeast Research
, vol.5
, pp. 63-72
-
-
Jha, S.1
Dabas, N.2
Karnani, N.3
Saini, P.4
Prasad, R.5
-
21
-
-
0033870569
-
Efflux-mediated resistance to fluconazole could be modulated by sterol homeostasis in Saccharomyces cerevisiae
-
Kontoyiannis, D.P. (2000). Efflux-mediated resistance to fluconazole could be modulated by sterol homeostasis in Saccharomyces cerevisiae. J. Antimicrob. Chemother. 46, 199-203.
-
(2000)
J. Antimicrob. Chemother.
, vol.46
, pp. 199-203
-
-
Kontoyiannis, D.P.1
-
22
-
-
77956223495
-
Employing information theoretic measures and mutagenesis to identify residues critical for drug-proton antiport function in Mdr1p of Candida albicans
-
Kapoor, K., Rehan, M., Lynn, A.M., and Prasad, R. (2010). Employing information theoretic measures and mutagenesis to identify residues critical for drug-proton antiport function in Mdr1p of Candida albicans. PLoS ONE5, e11041
-
(2010)
PLoS ONE5
-
-
Kapoor, K.1
Rehan, M.2
Lynn, A.M.3
Prasad, R.4
-
23
-
-
0034842947
-
Specificity of drug transport mediated by CaMDR1: a major facilitator of Candida albicans
-
Kohli, A., Gupta, V., Krishnamurthy, S., Hasnain, S.E., and Prasad, R. (2001). Specificity of drug transport mediated by CaMDR1: a major facilitator of Candida albicans. J. Biosci. 26, 333-339.
-
(2001)
J. Biosci.
, vol.26
, pp. 333-339
-
-
Kohli, A.1
Gupta, V.2
Krishnamurthy, S.3
Hasnain, S.E.4
Prasad, R.5
-
24
-
-
0031909801
-
Characterisation of human steroid hormone transport mediated by Cdr1p, multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family
-
Krishnamurthy, S., Gupta, V., Snehlata, P, and Prasad, R. (1998a). Characterisation of human steroid hormone transport mediated by Cdr1p, multidrug transporter of Candida albicans, belonging to the ATP binding cassette super family. FEMS Microbiol. Lett. 158:69-74
-
(1998)
FEMS Microbiol. Lett.
, vol.158
, pp. 69-74
-
-
Krishnamurthy, S.1
Gupta, V.2
Snehlata, P.3
Prasad, R.4
-
25
-
-
0032521514
-
Expression of CDR1, a multidrug resistance gene of Candida albicans: In vitro transcriptional activation by heat shock, drugs and human steroid hormones
-
Krishnamurthy S, Gupta V, Prasad R, Panwar SL, and Prasad R. (1998b). Expression of CDR1, a multidrug resistance gene of Candida albicans: In vitro transcriptional activation by heat shock, drugs and human steroid hormones. FEMS Microbiol. Lett. 160, 191-197.
-
(1998)
FEMS Microbiol. Lett.
, vol.160
, pp. 191-197
-
-
Krishnamurthy, S.1
Gupta, V.2
Prasad, R.3
Panwar, S.L.4
Prasad, R.5
-
26
-
-
77954659343
-
Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and non inte rchangeable
-
Kumar A., Shukla, S., Mandal, A., Shukla, S., Ambudkar, S.V., and Prasad, R. (2010). Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and non inte rchangeable. Biochimica et Biophysica Acta, 1798, 1757-1766.
-
(2010)
Biochimica et Biophysica Acta
, vol.1798
, pp. 1757-1766
-
-
Kumar, A.1
Shukla, S.2
Mandal, A.3
Shukla, S.4
Ambudkar, S.V.5
Prasad, R.6
-
27
-
-
73749088513
-
Fungal PDR transporters: Phylogeny, topology, motifs and function
-
Lamping, E., Baret, P.V., Holmes, A.R., Monk, B.C., Goffeau, A., and Cannon, R.D., (2010). Fungal PDR transporters: Phylogeny, topology, motifs and function. Fungal Genet. Biol. 47, 117-142.
-
(2010)
Fungal Genet. Biol.
, vol.47
, pp. 117-142
-
-
Lamping, E.1
Baret, P.V.2
Holmes, A.R.3
Monk, B.C.4
Goffeau, A.5
Cannon, R.D.6
-
28
-
-
0029815138
-
The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroidsin vivo
-
Mahe, Y., Lemoine, Y., and Kuchler, K. (1996). The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroidsin vivo. J. Biol. Chem. 271, 26167-26172.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26167-26172
-
-
Mahe, Y.1
Lemoine, Y.2
Kuchler, K.3
-
29
-
-
84864373260
-
A key structural domain of the Candida albicans Mdr1 protein
-
Mandal, A., Kumar, A., Singh, A., Lynn, A.M., Kapoor, K., and Prasad, R., (2012). A key structural domain of the Candida albicans Mdr1 protein. Biochem. J. 445, 313-322.
-
(2012)
Biochem. J.
, vol.445
, pp. 313-322
-
-
Mandal, A.1
Kumar, A.2
Singh, A.3
Lynn, A.M.4
Kapoor, K.5
Prasad, R.6
-
30
-
-
0027507306
-
A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport
-
Marger, M.D., and Saier, M.H. Jr. (1993). A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Trends Biochem. Sci. 18, 13-20.
-
(1993)
Trends Biochem. Sci.
, vol.18
, pp. 13-20
-
-
Marger, M.D.1
Saier Jr, M.H.2
-
31
-
-
0035197420
-
The large cytoplasmic loop of the glucose transporter GLUT1 is an essential structural element for function
-
Monden, I., Olsowski, A., Krause, G, and Keller, K. (2001). The large cytoplasmic loop of the glucose transporter GLUT1 is an essential structural element for function. Biol. Chem. 382, 1551-1558.
-
(2001)
Biol. Chem.
, vol.382
, pp. 1551-1558
-
-
Monden, I.1
Olsowski, A.2
Krause, G.3
Keller, K.4
-
32
-
-
54249119722
-
Sorting signals within the Saccharomyces cerevisiae sporulation-specific dityrosine transporter, Dtr1p C terminus promote Golgi-to-prospore membrane transport
-
Morishita, M., and Engebrecht, J. (2008). Sorting signals within the Saccharomyces cerevisiae sporulation-specific dityrosine transporter, Dtr1p, C terminus promote Golgi-to-prospore membrane transport. Eukaryotic Cell. 7, 1674-1684.
-
(2008)
Eukaryotic Cell
, vol.7
, pp. 1674-1684
-
-
Morishita, M.1
Engebrecht, J.2
-
33
-
-
0026535292
-
Isolation and sequence analysis of the gene for translation elongation factor 3 from Candida albicans
-
Myers, K.K., Fonzi, W.A., and Sypherd P.S. (1992). Isolation and sequence analysis of the gene for translation elongation factor 3 from Candida albicans. Nucleic Acids Res. 20, 1705-1710.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 1705-1710
-
-
Myers, K.K.1
Fonzi, W.A.2
Sypherd, P.S.3
-
34
-
-
84864809458
-
Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a D-octapeptide derivative inhibitor
-
Niimi, K., Harding, D.R., Holmes, A.R., Lamping, E., Niimi, M., Tyndall, J.D., Cannon, R.D., and Monk, B.C. (2012). Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a D-octapeptide derivative inhibitor. Mol. Microbiol. 85, 747-767.
-
(2012)
Mol. Microbiol.
, vol.85
, pp. 747-767
-
-
Niimi, K.1
Harding, D.R.2
Holmes, A.R.3
Lamping, E.4
Niimi, M.5
Tyndall, J.D.6
Cannon, R.D.7
Monk, B.C.8
-
35
-
-
55549140533
-
Mapping of interdomain interfaces required for the functional architecture of Yor1p, a eukaryotic ATP-binding cassette (ABC) transporter
-
Pagant, S., Brovman, E.Y., Halliday, J.J., and Miller, E.A., (2008). Mapping of interdomain interfaces required for the functional architecture of Yor1p, a eukaryotic ATP-binding cassette (ABC) transporter. J. Biol. Chem. 283, 26444-51.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26444-26451
-
-
Pagant, S.1
Brovman, E.Y.2
Halliday, J.J.3
Miller, E.A.4
-
36
-
-
78449252630
-
Intragenic suppressing mutations correct the folding and intracellular traffic of misfolded mutants of Yor1p, a eukaryotic drug transporter
-
Pagant, S., Halliday, J.J., Kougentakis, C., and Miller, EA. (2010). Intragenic suppressing mutations correct the folding and intracellular traffic of misfolded mutants of Yor1p, a eukaryotic drug transporter. J. Biol. Chem. 285, 36304-14.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 36304-36314
-
-
Pagant, S.1
Halliday, J.J.2
Kougentakis, C.3
Miller, E.A.4
-
37
-
-
33947672774
-
Structure and function analysis of CaMdr1p, a MFS antifungal efflux transporter protein of Candida albicans: identification of amino acid residues critical for drug/H+ transport
-
Pasrija, R., Banerjee, D., and Prasad, R. (2007). Structure and function analysis of CaMdr1p, a MFS antifungal efflux transporter protein of Candida albicans: identification of amino acid residues critical for drug/H+ transport. Eukaryot. Cell. 6, 443-453.
-
(2007)
Eukaryot. Cell.
, vol.6
, pp. 443-453
-
-
Pasrija, R.1
Banerjee, D.2
Prasad, R.3
-
38
-
-
0027408932
-
Topology, structure and evolution of two families of proteins involved in antibiotic and antiseptic resistance in eukaryotes and prokaryotes- an analysis
-
Paulsen, I.T., and Skurray, R.A. (1993). Topology, structure and evolution of two families of proteins involved in antibiotic and antiseptic resistance in eukaryotes and prokaryotes- an analysis. Gene. 124, 1-11.
-
(1993)
Gene
, vol.124
, pp. 1-11
-
-
Paulsen, I.T.1
Skurray, R.A.2
-
39
-
-
0029845047
-
Proton-dependent multidrug efflux systems
-
Paulsen, I.T., Brown, M.H. and Skurray, R.A. (1996). Proton-dependent multidrug efflux systems. Microbiol. Rev. 60, 575-608.
-
(1996)
Microbiol. Rev.
, vol.60
, pp. 575-608
-
-
Paulsen, I.T.1
Brown, M.H.2
Skurray, R.A.3
-
40
-
-
79955625171
-
Current perspectives on echinocandin class drugs
-
Perlin, D.S. (2011). Current perspectives on echinocandin class drugs. Future Microbiol. 6, 41-57.
-
(2011)
Future Microbiol
, vol.6
, pp. 41-57
-
-
Perlin, D.S.1
-
41
-
-
33846466508
-
Epidemiology of invasive candidiasis: a persistent public health problem
-
Pfaller, M.A., and Diekema, D.J. (2007). Epidemiology of invasive candidiasis: a persistent public health problem. Clin. Microbiol. Rev. 20, 133-163.
-
(2007)
Clin. Microbiol. Rev.
, vol.20
, pp. 133-163
-
-
Pfaller, M.A.1
Diekema, D.J.2
-
42
-
-
0028928549
-
Molecular cloning and characterisation of a novel gene of C. albicans, CDR1, conferring multiple resistance to drugs and antifungals
-
Prasad, R., Worgifosse, P.D., Goffeau, A., and Balzi, E. (1995). Molecular cloning and characterisation of a novel gene of C. albicans, CDR1, conferring multiple resistance to drugs and antifungals. Curr. Genet. 27, 320-329.
-
(1995)
Curr. Genet.
, vol.27
, pp. 320-329
-
-
Prasad, R.1
Worgifosse, P.D.2
Goffeau, A.3
Balzi, E.4
-
43
-
-
0035985631
-
Drug resistance in yeasts as an emerging scenario
-
Prasad, R., Panwar, S.L., and Smriti. (2002). Drug resistance in yeasts as an emerging scenario. Adv. Microb. Physiol. 46, 155-201.
-
(2002)
Adv. Microb. Physiol.
, vol.46
, pp. 155-201
-
-
Prasad, R.1
Panwar, S.L.2
Smriti3
-
45
-
-
84869109254
-
Functionally relevant residues of Cdr1p: a multidrug ABC transporter of human pathogenic Candida albicans
-
Prasad, R., Sharma, M., and Rawal, M.K. (2011). Functionally relevant residues of Cdr1p: a multidrug ABC transporter of human pathogenic Candida albicans. Amino Acids 2011, 531411
-
(2011)
Amino Acids
, vol.2011
, pp. 531411
-
-
Prasad, R.1
Sharma, M.2
Rawal, M.K.3
-
46
-
-
84855800113
-
Alanine scanning of all cysteines and construction of a functional cysteine-less Cdr1p, a multidrug ABC transporter of Candida albicans
-
Prasad, R., Shah, A.H., Sanwal, H., and Kapoor, K. (2012a) Alanine scanning of all cysteines and construction of a functional cysteine-less Cdr1p, a multidrug ABC transporter of Candida albicans. Biochem. Biophy. Res. Commun. 417, 508-513.
-
(2012)
Biochem. Biophy. Res. Commun.
, vol.417
, pp. 508-513
-
-
Prasad, R.1
Shah, A.H.2
Sanwal, H.3
Kapoor, K.4
-
47
-
-
84858704434
-
Yeast ATP binding cassette transporters conferring multidrug resistance
-
Prasad, R., and Goffeau, A. (2012b). Yeast ATP binding cassette transporters conferring multidrug resistance. Annu. Rev. Microbiol. 66:39-63.
-
(2012)
Annu. Rev. Microbiol.
, vol.66
, pp. 39-63
-
-
Prasad, R.1
Goffeau, A.2
-
48
-
-
68749120814
-
The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport
-
Puri, N., Gaur, M., Sharma, M., Shukla, S., Ambudkar, S.V., and Prasad, R. (2009). The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport. Biochim. Biophys. Acta. 1788, 1752-1761.
-
(2009)
Biochim. Biophys. Acta.
, vol.1788
, pp. 1752-1761
-
-
Puri, N.1
Gaur, M.2
Sharma, M.3
Shukla, S.4
Ambudkar, S.V.5
Prasad, R.6
-
49
-
-
77957827706
-
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans
-
Puri, N., Prakash, O., Manoharlal, R., Sharma, M., Ghosh, I., and Prasad, R. (2010). Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. Eur. J. Med. Chem. 45, 4813-26.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 4813-4826
-
-
Puri, N.1
Prakash, O.2
Manoharlal, R.3
Sharma, M.4
Ghosh, I.5
Prasad, R.6
-
50
-
-
17844379452
-
Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: Uncommon but conserved Trp326 of Walker B is important for ATP binding
-
Rai, V., Shukla, S., Jha, S., Komath, S.S., and Prasad, R. (2005). Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: Uncommon but conserved Trp326 of Walker B is important for ATP binding. Biochemistry. 44, 6650-6661.
-
(2005)
Biochemistry
, vol.44
, pp. 6650-6661
-
-
Rai, V.1
Shukla, S.2
Jha, S.3
Komath, S.S.4
Prasad, R.5
-
51
-
-
33845422375
-
Conserved Asp327 of walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis
-
Rai, V., Gaur, M., Shukla, S., Shukla, S., Ambudkar, S.V., Komath, S.S., and Prasad, R. (2006). Conserved Asp327 of walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis. Biochemistry. 45, 14726-14739.
-
(2006)
Biochemistry
, vol.45
, pp. 14726-14739
-
-
Rai, V.1
Gaur, M.2
Shukla, S.3
Shukla, S.4
Ambudkar, S.V.5
Komath, S.S.6
Prasad, R.7
-
52
-
-
52049084793
-
A novel catalytic mechanism for ATP hydrolysis employed by the N-terminal nucleotide-binding domain of Cdr1p, a multidrug ABC transporter of Candida albicans
-
Rai, V., Gaur, M., Kumar, A., Shukla, S., Komath, S.S., and Prasad, R. (2008). A novel catalytic mechanism for ATP hydrolysis employed by the N-terminal nucleotide-binding domain of Cdr1p, a multidrug ABC transporter of Candida albicans. Biochim. Biophys. Acta. 1778, 2143- 53.
-
(2008)
Biochim. Biophys. Acta.
, vol.1778
, pp. 2143-2153
-
-
Rai, V.1
Gaur, M.2
Kumar, A.3
Shukla, S.4
Komath, S.S.5
Prasad, R.6
-
53
-
-
84883203473
-
Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains
-
Rawal, M.K., Khan, M.F., Kapoor, K., Goyal, N., Sen, S., Saxena, A.K., Lynn, A.M., Tyndal, J. D.A., Monk, B.C., Cannon, R.D., Komath, S.S., and Prasad, R. (2013). Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains. J. Biol. Chem. 288, 24480-24493.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 24480-24493
-
-
Rawal, M.K.1
Khan, M.F.2
Kapoor, K.3
Goyal, N.4
Sen, S.5
Saxena, A.K.6
Lynn, A.M.7
Tyndal, J.D.A.8
Monk, B.C.9
Cannon, R.D.10
Komath, S.S.11
Prasad, R.12
-
54
-
-
0031974651
-
A Ste6p/P-glycoprotein homologue from the asexual yeast Candida albicans transports the a-factor mating pheromone in Saccharomyces cerevisiae
-
Raymond, M.D., Dignard, A.M., Alarco, N., Mainville, B.B., Magee, and Thomas, D.Y. (1998). A Ste6p/P-glycoprotein homologue from the asexual yeast Candida albicans transports the a-factor mating pheromone in Saccharomyces cerevisiae. Mol. Microbiol. 27, 587-598.
-
(1998)
Mol. Microbiol.
, vol.27
, pp. 587-598
-
-
Raymond, M.D.1
Dignard, A.M.2
Alarco, N.3
Mainville, B.B.4
Magee, T.D.Y.5
-
55
-
-
24144451315
-
Changing patterns and trends in systemic function infections
-
Richardson, D. M. (2005) Changing patterns and trends in systemic function infections. J. Antimicrob. Chemother. 56, 5-112.
-
(2005)
J. Antimicrob. Chemother.
, vol.56
, pp. 5-112
-
-
Richardson, D.M.1
-
56
-
-
0037097024
-
Cytoplasmic domains of the reduced folate carrier are essential for trafficking, but not function
-
Sadlish, H., Williams, F.M., and Flintoff, W.F. (2002). Cytoplasmic domains of the reduced folate carrier are essential for trafficking, but not function. J. Biochem. 364, 777-786.
-
(2002)
J. Biochem.
, vol.364
, pp. 777-786
-
-
Sadlish, H.1
Williams, F.M.2
Flintoff, W.F.3
-
57
-
-
0000983053
-
Families and super families of transport proteins common to prokaryotes and eukaryotes
-
Saier, M.H. Jr., and Reizer, J. (1991). Families and super families of transport proteins common to prokaryotes and eukaryotes. Curr. Opinion Struct. Biol. 1, 362-368.
-
(1991)
Curr. Opinion Struct. Biol.
, vol.1
, pp. 362-368
-
-
Saier Jr, M.H.1
Reizer, J.2
-
58
-
-
33644873454
-
TCDB: the transporter classification database for membrane transport protein analyses and information
-
Saier, M.H. Jr, Tran, C.V., and Barabote, R.D. (2006). TCDB: the transporter classification database for membrane transport protein analyses and information. Nucleic Acids Res. 34, D181-D186.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Saier Jr, M.H.1
Tran, C.V.2
Barabote, R.D.3
-
59
-
-
24044514014
-
Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux
-
Saini, P., Prasad, T., Gaur, N.A., Shukla, S., Jha, S., Komath, S.S., Khan, L.A., Haq, Q.M. R., and Prasad, R. (2005). Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux. J. Antimicrob. Chemother. 56, 77-86.
-
(2005)
J. Antimicrob. Chemother.
, vol.56
, pp. 77-86
-
-
Saini, P.1
Prasad, T.2
Gaur, N.A.3
Shukla, S.4
Jha, S.5
Komath, S.S.6
Khan, L.A.7
Haq, Q.M.R.8
Prasad, R.9
-
60
-
-
33646813997
-
Chimeras of the ABC drug transporter Cdr1p reveal functional indispensability of transmembrane domains and nucleotide-binding domains, but transmembrane segment 12 is replaceable with the corresponding homologous region of the non-drug transporter Cdr3p
-
Saini, P., Gaur, N.A., and Prasad, R. (2006). Chimeras of the ABC drug transporter Cdr1p reveal functional indispensability of transmembrane domains and nucleotide-binding domains, but transmembrane segment 12 is replaceable with the corresponding homologous region of the non-drug transporter Cdr3p. Microbiology. 152, 1559-1573.
-
(2006)
Microbiology
, vol.152
, pp. 1559-1573
-
-
Saini, P.1
Gaur, N.A.2
Prasad, R.3
-
61
-
-
0031047670
-
Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterisation of CDR2, a new multidrug ABC transporter gene
-
Sanglard, D., Ischer, F., Monod, M., and Bille, J. (1997). Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterisation of CDR2, a new multidrug ABC transporter gene. Microbiology. 143, 405-416.
-
(1997)
Microbiology
, vol.143
, pp. 405-416
-
-
Sanglard, D.1
Ischer, F.2
Monod, M.3
Bille, J.4
-
62
-
-
58049197842
-
Mutations define cross-talk between the N-terminal nucleotide binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport
-
Sauna, Z.E., Bohn, S.S., Rutledge, R., Dougherty, M.P., Cronin, S., May, L., Xia, D., Ambudkar, S.V., and Golin, J. (2008). Mutations define cross-talk between the N-terminal nucleotide binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport. J. Biol. Chem. 283, 35010-35022.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 35010-35022
-
-
Sauna, Z.E.1
Bohn, S.S.2
Rutledge, R.3
Dougherty, M.P.4
Cronin, S.5
May, L.6
Xia, D.7
Ambudkar, S.V.8
Golin, J.9
-
63
-
-
0347694571
-
Functional characterization of Candida albicans ABC transporter Cdr1p
-
Shukla, S., Saini, P., Smriti, Jha, S., Ambudkar, S.V., and Prasad, R. (2003). Functional characterization of Candida albicans ABC transporter Cdr1p. Eukaryot Cell. 2, 1361-1375.
-
(2003)
Eukaryot Cell
, vol.2
, pp. 1361-1375
-
-
Shukla, S.1
Saini, P.2
Smriti, J.S.3
Ambudkar, S.V.4
Prasad, R.5
-
64
-
-
33144465390
-
Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: purified protein is amenable to intrinsic fluorescence analysis
-
Shukla, S., Rai, V., Banerjee, D., and Prasad, R. (2006). Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: purified protein is amenable to intrinsic fluorescence analysis. Biochemistry. 45, 2425-2435.
-
(2006)
Biochemistry
, vol.45
, pp. 2425-2435
-
-
Shukla, S.1
Rai, V.2
Banerjee, D.3
Prasad, R.4
-
65
-
-
0037085683
-
ABC transporters Cdr1p Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators
-
Smriti, Krishnamurthy, S., Dixit, B.L., Gupta, C.M., Milewski, S., and Prasad, R. (2002). ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators. Yeast. 19, 303-318.
-
(2002)
Yeast
, vol.19
, pp. 303-318
-
-
Smriti1
Krishnamurthy, S.2
Dixit, B.L.3
Gupta, C.M.4
Milewski, S.5
Prasad, R.6
-
66
-
-
0021043960
-
Ketoconazole binds to the intracellular corticosteroid-binding protein in Candida albicans
-
Stover, E.P., Loose, D.S., Stevens, D.A., and Feldman, D. (1983). Ketoconazole binds to the intracellular corticosteroid-binding protein in Candida albicans. Biochem Biophys Res Commun. 117, 43-50.
-
(1983)
Biochem Biophys Res Commun
, vol.117
, pp. 43-50
-
-
Stover, E.P.1
Loose, D.S.2
Stevens, D.A.3
Feldman, D.4
-
67
-
-
0031716416
-
Disruption studies of a Candida albicans gene ELF1: a member of the ATP-binding cassette family
-
Sturtevant, J., Cihlar, R., and Calderone, R. (1998). Disruption studies of a Candida albicans gene, ELF1: a member of the ATP-binding cassette family. Microbiology. 144, 2311-2321.
-
(1998)
Microbiology
, vol.144
, pp. 2311-2321
-
-
Sturtevant, J.1
Cihlar, R.2
Calderone, R.3
-
68
-
-
0034255257
-
The central cytoplasmic loop of the major facilitator superfamily of transport proteins governs efficient membrane insertion
-
Weinglass, A.B. and Kaback, H.R. (2000). The central cytoplasmic loop of the major facilitator superfamily of transport proteins governs efficient membrane insertion. Proc. Natl. Acad. Sci. U.S.A. 97, 8938-8943.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 8938-8943
-
-
Weinglass, A.B.1
Kaback, H.R.2
-
69
-
-
78649969385
-
Functional role of the intracellular loop linking transmembrane domains 6 and 7 of the human dipeptide transporter hPEPT1
-
Xu, L., Li, Y., Haworth, I.S. and Davies, D.L. (2010). Functional role of the intracellular loop linking transmembrane domains 6 and 7 of the human dipeptide transporter hPEPT1. J. Membr. Biol. 238, 43-49.
-
(2010)
J. Membr. Biol
, vol.238
, pp. 43-49
-
-
Xu, L.1
Li, Y.2
Haworth, I.S.3
Davies, D.L.4
|