Intragenic suppressing mutations correct the folding and intracellular traffic of misfolded mutants of Yor1p, a eukaryotic drug transporter

Journal of Biological Chemistry

Volumn 285, Issue 47, 2010, Pages 36304-36314

  Pagant, Silvere ^a   Halliday, John J ^a   Kougentakis, Christos ^a   Miller, Elizabeth A ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ATP-BINDING CASSETTE TRANSPORTERS; ENDOPLASMIC RETICULUM; INTER-DOMAIN; INTRACELLULAR LOOP; ION FLUXES; NUCLEOTIDE-BINDING DOMAIN; PHENYLALANINE RESIDUES; STRUCTURAL MODULE; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE HELICES; YEAST PROTEINS;

ACTIVATION ANALYSIS; AMINO ACIDS; PATHOLOGY; PROTEINS; RESTORATION;

ION EXCHANGE;

ABC TRANSPORTER; ARGININE; GLYCINE; ISOLEUCINE; METHIONINE; MUTANT PROTEIN; NUCLEOTIDE BINDING PROTEIN; PHENYLALANINE; PROLINE; PROTEIN YOR1P; SERINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; INTRACELLULAR TRANSPORT; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT;

ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOPLASM; ENDOPLASMIC RETICULUM; HUMANS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUPPRESSION, GENETIC;

EUKARYOTA;

EID: 78449252630     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.142760     Document Type: Article

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