-
1
-
-
0346887115
-
Structure and function of efflux pumps that confer resistance to drugs
-
Borges-Walmsey MJ, McKeegan K, Walmsey AR. 2003. Structure and function of efflux pumps that confer resistance to drugs. Biochem. J. 376: 313-338.
-
(2003)
Biochem. J.
, vol.376
, pp. 313-338
-
-
Borges-Walmsey, M.J.1
McKeegan, K.2
Walmsey, A.R.3
-
3
-
-
0022515908
-
Isolation and characterization of DNA sequences amplified in multidrug resistant human cells
-
Gros P, Croop J, Roninson I, Varshavsky A, Housman DE. 1986. Isolation and characterization of DNA sequences amplified in multidrug resistant human cells. Proc. Natl. Acad. Sci. U. S. A. 83:337-341.
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 337-341
-
-
Gros, P.1
Croop, J.2
Roninson, I.3
Varshavsky, A.4
Housman, D.E.5
-
4
-
-
0021288268
-
Amplification of specific DNA sequences correlates with multidrug resistance in Chinese hamster cells
-
Roninson IB, Abelson HT, Housman DE, Howell N, Varshavsky A. 1984. Amplification of specific DNA sequences correlates with multidrug resistance in Chinese hamster cells. Nature 309:626-628.
-
(1984)
Nature
, vol.309
, pp. 626-628
-
-
Roninson, I.B.1
Abelson, H.T.2
Housman, D.E.3
Howell, N.4
Varshavsky, A.5
-
5
-
-
0022610102
-
Overexpression and amplification of five genes in a multidrug resistant Chinese hamster ovary cell line
-
Van der Bliek AM, Van der Velde-Koerts, Ling TV, Borst P. 1986. Overexpression and amplification of five genes in a multidrug resistant Chinese hamster ovary cell line. Mol. Cell. Biol. 6:1671-1678.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 1671-1678
-
-
Van Der Bliek, A.M.1
Van Der Velde-Koerts Ling, T.V.2
Borst, P.3
-
6
-
-
0343903983
-
Single nuclear gene inherited crossresistance and collateral sensitivity to 17 inhibitors of mitochondrial function in Saccharomyces cerevisiae
-
Rank GH, Bech-Hansen NJ. 1973. Single nuclear gene inherited crossresistance and collateral sensitivity to 17 inhibitors of mitochondrial function in Saccharomyces cerevisiae. Mol. Gen. Genet. 126:93-102.
-
(1973)
Mol. Gen. Genet.
, vol.126
, pp. 93-102
-
-
Rank, G.H.1
Bech-Hansen, N.J.2
-
7
-
-
0025237430
-
Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces
-
Leppert G, McDevitt R, Falco SC, Van Dyk T, Ficke MB, Golin J. 1990. Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces. Genetics 125:13-20.
-
(1990)
Genetics
, vol.125
, pp. 13-20
-
-
Leppert, G.1
McDevitt, R.2
Falco, S.C.3
Van Dyk, T.4
Ficke, M.B.5
Golin, J.6
-
8
-
-
0028082188
-
Pdr5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator Pdr1
-
Balzi E, Wang M, Leterme S, Van Dyck L, Goffeau A. 1994. Pdr5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator Pdr1. J. Biol. Chem. 269:2206-2214.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2206-2214
-
-
Balzi, E.1
Wang, M.2
Leterme, S.3
Van Dyck, L.4
Goffeau, A.5
-
9
-
-
0028041072
-
Saccharomyces cerevisiae Ydr1, which encodes a member of the ATP-binding cassette superfamily, is required for multidrug resistance
-
Hirata D, Yano K, Miyahara K, Miyakawa R. 1994. Saccharomyces cerevisiae Ydr1, which encodes a member of the ATP-binding cassette superfamily, is required for multidrug resistance. Curr. Genet. 26:285-294.
-
(1994)
Curr. Genet.
, vol.26
, pp. 285-294
-
-
Hirata, D.1
Yano, K.2
Miyahara, K.3
Miyakawa, R.4
-
10
-
-
0027497594
-
Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitoquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases
-
Servos J, Haase E, Brendel M. 1993. Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitoquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases. Mol. Gen. Genet. 236:214-218.
-
(1993)
Mol. Gen. Genet.
, vol.236
, pp. 214-218
-
-
Servos, J.1
Haase, E.2
Brendel, M.3
-
11
-
-
0028111508
-
Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance
-
Bissinger PH, Kuchler K. 1994. Molecular cloning and expression of the Saccharomyces cerevisiae STS1 gene product. A yeast ABC transporter conferring mycotoxin resistance. J. Biol. Chem. 269:4180-4186.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4180-4186
-
-
Bissinger, P.H.1
Kuchler, K.2
-
12
-
-
0028807740
-
Expression of an ATP-binding cassette transporter gene YOR1 is required for oligomycin resistance in Saccharomyces cerevisiae
-
Katzmann DJ, Hallstrom TC, Voet M, Wysock W, Golin J, Volckaert G, Moye-Rowley WS. 1995. Expression of an ATP-binding cassette transporter gene YOR1 is required for oligomycin resistance in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:6875-6883.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 6875-6883
-
-
Katzmann, D.J.1
Hallstrom, T.C.2
Voet, M.3
Wysock, W.4
Golin, J.5
Volckaert, G.6
Moye-Rowley, W.S.7
-
13
-
-
0026602838
-
Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5
-
Meyers S, Schauer W, Balzi E, Wagner M, Goffeau A, Golin J. 1992. Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5. Curr. Genet. 21:431-436.
-
(1992)
Curr. Genet.
, vol.21
, pp. 431-436
-
-
Meyers, S.1
Schauer, W.2
Balzi, E.3
Wagner, M.4
Goffeau, A.5
Golin, J.6
-
14
-
-
0037458550
-
Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic efflux
-
Golin J, Ambudkar SV, Gottesman MM, Habib AD, Sczepanski J, Ziccardi W, May L. 2003. Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic efflux. J. Biol. Chem. 278: 5963-5969.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5963-5969
-
-
Golin, J.1
Ambudkar, S.V.2
Gottesman, M.M.3
Habib, A.D.4
Sczepanski, J.5
Ziccardi, W.6
May, L.7
-
15
-
-
0035080844
-
The pleiotropic drug ABC transporters from Saccharomyces cerevisiae
-
Rogers B, Decottignies A, Kolaczkowski M, Caravajal E, Balzi E, Goffeau A. 2001. The pleiotropic drug ABC transporters from Saccharomyces cerevisiae. J. Mol. Microbiol. Biotechnol. 3:207-214.
-
(2001)
J. Mol. Microbiol. Biotechnol.
, vol.3
, pp. 207-214
-
-
Rogers, B.1
Decottignies, A.2
Kolaczkowski, M.3
Caravajal, E.4
Balzi, E.5
Goffeau, A.6
-
16
-
-
78751582384
-
Toward and understanding of the mechanism of action of the yeast multidrug resistance transporter Pdr5p: A molecular modeling study
-
Rutledge R, Esser L, Ma J, Xia D. 2011. Toward and understanding of the mechanism of action of the yeast multidrug resistance transporter Pdr5p: A molecular modeling study. J. Struct. Biol. 173:333-344.
-
(2011)
J. Struct. Biol.
, vol.173
, pp. 333-344
-
-
Rutledge, R.1
Esser, L.2
Ma, J.3
Xia, D.4
-
17
-
-
65249133460
-
Structural arrangement of the transmission interface of the antigen ABC transport complex TAP
-
Oancea G, O'Mara ML, Drew-Bennett W, Tielman P, Abeles R, Tampe R. 2009. Structural arrangement of the transmission interface of the antigen ABC transport complex TAP. Proc. Natl. Acad. Sci. U. S. A. 106:5551-5556.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 5551-5556
-
-
Oancea, G.1
O'Mara, M.L.2
Drew-Bennett, W.3
Tielman, P.4
Abeles, R.5
Tampe, R.6
-
18
-
-
36849079744
-
Evidence for a Sav1866-like architecture for the human multidrug transporter P-glycoprotein
-
Zolnerciks JK, Wooding C, Linton KJ. 2007. Evidence for a Sav1866-like architecture for the human multidrug transporter P-glycoprotein. FASEB J. 21:3937-3948.
-
(2007)
FASEB J.
, vol.21
, pp. 3937-3948
-
-
Zolnerciks, J.K.1
Wooding, C.2
Linton, K.J.3
-
19
-
-
33748644877
-
Structure of a bacterial multidrug ABC transporter
-
Dawson RJ, Locher KP. 2006. Structure of a bacterial multidrug ABC transporter. Nature 443:180-185.
-
(2006)
Nature
, vol.443
, pp. 180-185
-
-
Dawson, R.J.1
Locher, K.P.2
-
20
-
-
58049197842
-
Mutations define cross talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: Possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport
-
Sauna ZE, Bohn SS, Rutledge R, Dougherty MP, Cronin S, May L, Xia D, Ambudkar SV, Golin J. 2008. Mutations define cross talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: Possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport. J. Biol. Chem. 283:35010-35022.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 35010-35022
-
-
Sauna, Z.E.1
Bohn, S.S.2
Rutledge, R.3
Dougherty, M.P.4
Cronin, S.5
May, L.6
Xia, D.7
Ambudkar, S.V.8
Golin, J.9
-
21
-
-
77952810407
-
The signaling interface of the yeast multidrug transporter Pdr5 adopts a cis conformation and there are functional overlap and equivalence of the deviant and canonical Q-loop residues
-
Ananthaswamy N, Rutledge R, Sauna ZE, Dine E, Nelson E, Xia D, Golin J. 2010. The signaling interface of the yeast multidrug transporter Pdr5 adopts a cis conformation and there are functional overlap and equivalence of the deviant and canonical Q-loop residues. Biochemistry 49:4440-4449.
-
(2010)
Biochemistry
, vol.49
, pp. 4440-4449
-
-
Ananthaswamy, N.1
Rutledge, R.2
Sauna, Z.E.3
Dine, E.4
Nelson, E.5
Xia, D.6
Golin, J.7
-
22
-
-
36048941421
-
Complete inhibition of the Pdr5p multidrug efflux pump ATPase activity by its transport substrate clotrimazole suggests GTP as well as ATP may be used as an energy source
-
Golin J, Kon ZN, Wu CP, Martello J, Hanson L, Supernavage S, Ambudkar SV, Sauna Z. 2007. Complete inhibition of the Pdr5p multidrug efflux pump ATPase activity by its transport substrate clotrimazole suggests GTP as well as ATP may be used as an energy source. Biochemistry 46:18109-18119.
-
(2007)
Biochemistry
, vol.46
, pp. 18109-18119
-
-
Golin, J.1
Kon, Z.N.2
Wu, C.P.3
Martello, J.4
Hanson, L.5
Supernavage, S.6
Ambudkar, S.V.7
Sauna, Z.8
-
23
-
-
84855441982
-
A mutation in intracellular loop 4 affects the drug efflux activity of the yeast multidrug transporter Pdr5p
-
doi:10.1371/journal.pone.0029520
-
Guo X, Li J, Wang T, Liu Z, Chen X, Li Y, Gu Z, Mao X, Guan W, Li Y. 2012. A mutation in intracellular loop 4 affects the drug efflux activity of the yeast multidrug transporter Pdr5p. PLoS One 7:e29520. doi:10.1371 /journal.pone.0029520.
-
(2012)
PLoS One
, vol.7
-
-
Guo, X.1
Li, J.2
Wang, T.3
Liu, Z.4
Chen, X.5
Li, Y.6
Gu, Z.7
Mao, X.8
Guan, W.9
Li, Y.10
-
24
-
-
42449109037
-
A mutation of the H-loop selectively affects rhodamine transport by the yeast ABC transporter Pdr5
-
Ernst R, Kueppers P, Klein CM, Schwarzmueller T, Kuchler K, Schmitt L. 2008. A mutation of the H-loop selectively affects rhodamine transport by the yeast ABC transporter Pdr5. Proc. Natl. Acad. Sci. U. S. A. 105: 5069-5074.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 5069-5074
-
-
Ernst, R.1
Kueppers, P.2
Klein, C.M.3
Schwarzmueller, T.4
Kuchler, K.5
Schmitt, L.6
-
25
-
-
63449139456
-
Structure of P-glycoprotein reveals a molecular basis for polyspecific drug binding
-
Aller S, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Urbatsch IL, Chang G. 2009. Structure of P-glycoprotein reveals a molecular basis for polyspecific drug binding. Science 323:1718-1722.
-
(2009)
Science
, vol.323
, pp. 1718-1722
-
-
Aller, S.1
Yu, J.2
Ward, A.3
Weng, Y.4
Chittaboina, S.5
Zhuo, R.6
Harrell, P.M.7
Trinh, Y.T.8
Urbatsch, I.L.9
Chang, G.10
-
26
-
-
22244472651
-
The role of hydrogen bond acceptor groups in the interaction of substrates with Pdr5, a major yeast drug transporter
-
Hanson L, May L, Tuma P, Keeven J, Mehl P, Ferenz M, Ambudkar SV, Golin J. 2005. The role of hydrogen bond acceptor groups in the interaction of substrates with Pdr5, a major yeast drug transporter. Biochemistry 44:9703-9713.
-
(2005)
Biochemistry
, vol.44
, pp. 9703-9713
-
-
Hanson, L.1
May, L.2
Tuma, P.3
Keeven, J.4
Mehl, P.5
Ferenz, M.6
Ambudkar, S.V.7
Golin, J.8
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