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Volumn 47, Issue 2, 2010, Pages 127-142

Fungal PDR transporters: Phylogeny, topology, motifs and function

Author keywords

Antifungal; ATP binding cassette (ABC); Azoles; Multidrug resistance (MDR); PDR motif A; PDR motif B; Pleiotropic drug resistance (PDR)

Indexed keywords

ABC TRANSPORTER; AMPHOTERICIN B; CARRIER PROTEIN; FLUCONAZOLE; FLUCYTOSINE; FUNGAL PROTEIN; ITRACONAZOLE; MAJOR FACILITATOR SUPERFAMILY PROTEIN; PLEIOTROPIC DRUG RESISTANCE PROTEIN; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG; VORICONAZOLE;

EID: 73749088513     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2009.10.007     Document Type: Article
Times cited : (129)

References (125)
  • 1
    • 22744455661 scopus 로고    scopus 로고
    • An update on antifungal targets and mechanisms of resistance in Candida albicans
    • Akins R.A. An update on antifungal targets and mechanisms of resistance in Candida albicans. Med. Mycol. 43 4 (2005) 285-318
    • (2005) Med. Mycol. , vol.43 , Issue.4 , pp. 285-318
    • Akins, R.A.1
  • 2
    • 63449139456 scopus 로고    scopus 로고
    • Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
    • Aller S.G., Yu J., Ward A., Weng Y., Chittaboina S., et al. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 323 5922 (2009) 1718-1722
    • (2009) Science , vol.323 , Issue.5922 , pp. 1718-1722
    • Aller, S.G.1    Yu, J.2    Ward, A.3    Weng, Y.4    Chittaboina, S.5
  • 3
    • 0028082188 scopus 로고
    • PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1
    • Balzi E., Wang M., Leterme S., Van Dyck L., and Goffeau A. PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J. Biol. Chem. 269 3 (1994) 2206-2214
    • (1994) J. Biol. Chem. , vol.269 , Issue.3 , pp. 2206-2214
    • Balzi, E.1    Wang, M.2    Leterme, S.3    Van Dyck, L.4    Goffeau, A.5
  • 4
    • 0032720231 scopus 로고    scopus 로고
    • Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance
    • Bauer B.E., Wolfger H., and Kuchler K. Inventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance. Biochim. Biophys. Acta 1461 2 (1999) 217-236
    • (1999) Biochim. Biophys. Acta , vol.1461 , Issue.2 , pp. 217-236
    • Bauer, B.E.1    Wolfger, H.2    Kuchler, K.3
  • 5
    • 2142810157 scopus 로고    scopus 로고
    • Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis
    • Bennett J.E., Izumikawa K., and Marr K.A. Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis. Antimicrob. Agents Chemother. 48 5 (2004) 1773-1777
    • (2004) Antimicrob. Agents Chemother. , vol.48 , Issue.5 , pp. 1773-1777
    • Bennett, J.E.1    Izumikawa, K.2    Marr, K.A.3
  • 6
    • 0036795485 scopus 로고    scopus 로고
    • Phylogenetic and functional classification of ATP-binding cassette (ABC) systems
    • Bouige P., Laurent D., Piloyan L., and Dassa E. Phylogenetic and functional classification of ATP-binding cassette (ABC) systems. Curr. Protein Pept. Sci. 3 5 (2002) 541-559
    • (2002) Curr. Protein Pept. Sci. , vol.3 , Issue.5 , pp. 541-559
    • Bouige, P.1    Laurent, D.2    Piloyan, L.3    Dassa, E.4
  • 7
    • 0029300284 scopus 로고
    • Oral Candida: clearance, colonization, or candidiasis?
    • Cannon R.D., Holmes A.R., Mason A.B., and Monk B.C. Oral Candida: clearance, colonization, or candidiasis?. J. Dent. Res. 74 5 (1995) 1152-1161
    • (1995) J. Dent. Res. , vol.74 , Issue.5 , pp. 1152-1161
    • Cannon, R.D.1    Holmes, A.R.2    Mason, A.B.3    Monk, B.C.4
  • 9
    • 0038799725 scopus 로고    scopus 로고
    • Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation
    • Chang G. Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation. J. Mol. Biol. 330 2 (2003) 419-430
    • (2003) J. Mol. Biol. , vol.330 , Issue.2 , pp. 419-430
    • Chang, G.1
  • 10
    • 13244298189 scopus 로고    scopus 로고
    • Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma
    • Chen J., Li H., Li R., Bu D., and Wan Z. Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma. J. Antimicrob. Chemother. 55 1 (2005) 31-37
    • (2005) J. Antimicrob. Chemother. , vol.55 , Issue.1 , pp. 31-37
    • Chen, J.1    Li, H.2    Li, R.3    Bu, D.4    Wan, Z.5
  • 11
    • 0036569763 scopus 로고    scopus 로고
    • Morbidity and mortality in South African gold miners: impact of untreated disease due to human immunodeficiency virus
    • Corbett E.L., Churchyard G.J., Charalambos S., Samb B., Moloi V., et al. Morbidity and mortality in South African gold miners: impact of untreated disease due to human immunodeficiency virus. Clin. Infect. Dis. 34 9 (2002) 1251-1258
    • (2002) Clin. Infect. Dis. , vol.34 , Issue.9 , pp. 1251-1258
    • Corbett, E.L.1    Churchyard, G.J.2    Charalambos, S.3    Samb, B.4    Moloi, V.5
  • 12
    • 31844452561 scopus 로고    scopus 로고
    • Organization and function of the plant pleiotropic drug resistance ABC transporter family
    • Crouzet J., Trombik T., Fraysse A.S., and Boutry M. Organization and function of the plant pleiotropic drug resistance ABC transporter family. FEBS Lett. 580 4 (2006) 1123-1130
    • (2006) FEBS Lett. , vol.580 , Issue.4 , pp. 1123-1130
    • Crouzet, J.1    Trombik, T.2    Fraysse, A.S.3    Boutry, M.4
  • 14
    • 0035014565 scopus 로고    scopus 로고
    • The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms
    • Dassa E., and Bouige P. The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms. Res. Microbiol. 152 3-4 (2001) 211-229
    • (2001) Res. Microbiol. , vol.152 , Issue.3-4 , pp. 211-229
    • Dassa, E.1    Bouige, P.2
  • 15
    • 33746260403 scopus 로고    scopus 로고
    • Oral candidosis in patients with advanced cancer
    • Davies A.N., Brailsford S.R., and Beighton D. Oral candidosis in patients with advanced cancer. Oral Oncol. 42 7 (2006) 698-702
    • (2006) Oral Oncol. , vol.42 , Issue.7 , pp. 698-702
    • Davies, A.N.1    Brailsford, S.R.2    Beighton, D.3
  • 16
    • 33748644877 scopus 로고    scopus 로고
    • Structure of a bacterial multidrug ABC transporter
    • Dawson R.J., and Locher K.P. Structure of a bacterial multidrug ABC transporter. Nature 443 7108 (2006) 180-185
    • (2006) Nature , vol.443 , Issue.7108 , pp. 180-185
    • Dawson, R.J.1    Locher, K.P.2
  • 17
    • 5644233700 scopus 로고    scopus 로고
    • Immunopathogenesis of oropharyngeal candidiasis in human immunodeficiency virus infection
    • (table of contents)
    • de Repentigny L., Lewandowski D., and Jolicoeur P. Immunopathogenesis of oropharyngeal candidiasis in human immunodeficiency virus infection. Clin. Microbiol. Rev. 17 4 (2004) 729-759 (table of contents)
    • (2004) Clin. Microbiol. Rev. , vol.17 , Issue.4 , pp. 729-759
    • de Repentigny, L.1    Lewandowski, D.2    Jolicoeur, P.3
  • 19
    • 0031056684 scopus 로고    scopus 로고
    • Complete inventory of the yeast ABC proteins
    • Decottignies A., and Goffeau A. Complete inventory of the yeast ABC proteins. Nat. Genet. 15 2 (1997) 137-145
    • (1997) Nat. Genet. , vol.15 , Issue.2 , pp. 137-145
    • Decottignies, A.1    Goffeau, A.2
  • 21
    • 0033558105 scopus 로고    scopus 로고
    • A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA
    • Edgar R., and Bibi E. A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA. Embo. J. 18 4 (1999) 822-832
    • (1999) Embo. J. , vol.18 , Issue.4 , pp. 822-832
    • Edgar, R.1    Bibi, E.2
  • 22
    • 0034063860 scopus 로고    scopus 로고
    • The transmembrane domain 10 of the yeast Pdr5p ABC antifungal efflux pump determines both substrate specificity and inhibitor susceptibility
    • Egner R., Bauer B.E., and Kuchler K. The transmembrane domain 10 of the yeast Pdr5p ABC antifungal efflux pump determines both substrate specificity and inhibitor susceptibility. Mol. Microbiol. 35 5 (2000) 1255-1263
    • (2000) Mol. Microbiol. , vol.35 , Issue.5 , pp. 1255-1263
    • Egner, R.1    Bauer, B.E.2    Kuchler, K.3
  • 23
    • 42449109037 scopus 로고    scopus 로고
    • A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5
    • Ernst R., Kueppers P., Klein C.M., Schwarzmueller T., Kuchler K., et al. A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5. Proc. Natl. Acad. Sci. USA 105 13 (2008) 5069-5074
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , Issue.13 , pp. 5069-5074
    • Ernst, R.1    Kueppers, P.2    Klein, C.M.3    Schwarzmueller, T.4    Kuchler, K.5
  • 24
    • 22844435164 scopus 로고    scopus 로고
    • The ergosterol biosynthesis pathway, transporter genes, and azole resistance in Aspergillus fumigatus
    • Ferreira M.E., Colombo A.L., Paulsen I., Ren Q., Wortman J., et al. The ergosterol biosynthesis pathway, transporter genes, and azole resistance in Aspergillus fumigatus. Med. Mycol. 43 Suppl. 1 (2005) S313-319
    • (2005) Med. Mycol. , vol.43 , Issue.SUPPL. 1
    • Ferreira, M.E.1    Colombo, A.L.2    Paulsen, I.3    Ren, Q.4    Wortman, J.5
  • 25
    • 0038485609 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of the Saccharomyces cerevisiae multidrug resistance protein Pdr5p
    • Ferreira-Pereira A., Marco S., Decottignies A., Nader J., Goffeau A., et al. Three-dimensional reconstruction of the Saccharomyces cerevisiae multidrug resistance protein Pdr5p. J. Biol. Chem. 278 14 (2003) 11995-11999
    • (2003) J. Biol. Chem. , vol.278 , Issue.14 , pp. 11995-11999
    • Ferreira-Pereira, A.1    Marco, S.2    Decottignies, A.3    Nader, J.4    Goffeau, A.5
  • 27
    • 0030937576 scopus 로고    scopus 로고
    • Topological rules for membrane protein assembly in eukaryotic cells
    • Gafvelin G., Sakaguchi M., Andersson H., and von Heijne G. Topological rules for membrane protein assembly in eukaryotic cells. J. Biol. Chem. 272 10 (1997) 6119-6127
    • (1997) J. Biol. Chem. , vol.272 , Issue.10 , pp. 6119-6127
    • Gafvelin, G.1    Sakaguchi, M.2    Andersson, H.3    von Heijne, G.4
  • 28
    • 0034724680 scopus 로고    scopus 로고
    • Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1
    • Gao M., Cui H.R., Loe D.W., Grant C.E., Almquist K.C., et al. Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1. J. Biol. Chem. 275 17 (2000) 13098-13108
    • (2000) J. Biol. Chem. , vol.275 , Issue.17 , pp. 13098-13108
    • Gao, M.1    Cui, H.R.2    Loe, D.W.3    Grant, C.E.4    Almquist, K.C.5
  • 29
    • 27544514993 scopus 로고    scopus 로고
    • Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans
    • Gaur M., Choudhury D., and Prasad R. Complete inventory of ABC proteins in human pathogenic yeast, Candida albicans. J. Mol. Microbiol. Biotechnol. 9 1 (2005) 3-15
    • (2005) J. Mol. Microbiol. Biotechnol. , vol.9 , Issue.1 , pp. 3-15
    • Gaur, M.1    Choudhury, D.2    Prasad, R.3
  • 30
    • 0038335066 scopus 로고    scopus 로고
    • Functional similarities and differences between Candida albicans Cdr1p and Cdr2p transporters
    • Gauthier C., Weber S., Alarco A.M., Alqawi O., Daoud R., et al. Functional similarities and differences between Candida albicans Cdr1p and Cdr2p transporters. Antimicrob. Agents Chemother. 47 5 (2003) 1543-1554
    • (2003) Antimicrob. Agents Chemother. , vol.47 , Issue.5 , pp. 1543-1554
    • Gauthier, C.1    Weber, S.2    Alarco, A.M.3    Alqawi, O.4    Daoud, R.5
  • 31
    • 33645980973 scopus 로고    scopus 로고
    • Evolution of gene families: the multidrug resistance transporter genes in five related yeast species
    • Gbelska Y., Krijger J.J., and Breunig K.D. Evolution of gene families: the multidrug resistance transporter genes in five related yeast species. FEMS Yeast Res. 6 3 (2006) 345-355
    • (2006) FEMS Yeast Res. , vol.6 , Issue.3 , pp. 345-355
    • Gbelska, Y.1    Krijger, J.J.2    Breunig, K.D.3
  • 33
    • 0342351613 scopus 로고
    • Predicting the orientation of eukaryotic membrane-spanning proteins
    • Hartmann E., Rapoport T.A., and Lodish H.F. Predicting the orientation of eukaryotic membrane-spanning proteins. Proc. Natl. Acad. Sci. USA 86 15 (1989) 5786-5790
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , Issue.15 , pp. 5786-5790
    • Hartmann, E.1    Rapoport, T.A.2    Lodish, H.F.3
  • 34
    • 27744459366 scopus 로고    scopus 로고
    • Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2
    • Henriksen U., Fog J.U., Litman T., and Gether U. Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2. J. Biol. Chem. 280 44 (2005) 36926-36934
    • (2005) J. Biol. Chem. , vol.280 , Issue.44 , pp. 36926-36934
    • Henriksen, U.1    Fog, J.U.2    Litman, T.3    Gether, U.4
  • 35
    • 33947495735 scopus 로고    scopus 로고
    • Mechanism of substrate sensing and signal transmission within an ABC transporter: use of a Trojan horse strategy
    • Herget M., Oancea G., Schrodt S., Karas M., Tampe R., et al. Mechanism of substrate sensing and signal transmission within an ABC transporter: use of a Trojan horse strategy. J. Biol. Chem. 282 6 (2007) 3871-3880
    • (2007) J. Biol. Chem. , vol.282 , Issue.6 , pp. 3871-3880
    • Herget, M.1    Oancea, G.2    Schrodt, S.3    Karas, M.4    Tampe, R.5
  • 36
    • 0035019469 scopus 로고    scopus 로고
    • ABC transporters: physiology, structure and mechanism - an overview
    • Higgins C.F. ABC transporters: physiology, structure and mechanism - an overview. Res. Microbiol. 152 3-4 (2001) 205-210
    • (2001) Res. Microbiol. , vol.152 , Issue.3-4 , pp. 205-210
    • Higgins, C.F.1
  • 37
    • 34147214716 scopus 로고    scopus 로고
    • Multiple molecular mechanisms for multidrug resistance transporters
    • Higgins C.F. Multiple molecular mechanisms for multidrug resistance transporters. Nature 446 7137 (2007) 749-757
    • (2007) Nature , vol.446 , Issue.7137 , pp. 749-757
    • Higgins, C.F.1
  • 38
    • 4744358624 scopus 로고    scopus 로고
    • The ATP switch model for ABC transporters
    • Higgins C.F., and Linton K.J. The ATP switch model for ABC transporters. Nat. Struct. Mol. Biol. 11 10 (2004) 918-926
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , Issue.10 , pp. 918-926
    • Higgins, C.F.1    Linton, K.J.2
  • 39
    • 0032698874 scopus 로고    scopus 로고
    • ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
    • Holland I.B., and Blight M.A. ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans. J. Mol. Biol. 293 2 (1999) 381-399
    • (1999) J. Mol. Biol. , vol.293 , Issue.2 , pp. 381-399
    • Holland, I.B.1    Blight, M.A.2
  • 41
    • 55849083537 scopus 로고    scopus 로고
    • ABC transporter Cdr1p contributes more than Cdr2p does to fluconazole efflux in fluconazole-resistant Candida albicans clinical isolates
    • Holmes A.R., Lin Y.H., Niimi K., Lamping E., Keniya M., et al. ABC transporter Cdr1p contributes more than Cdr2p does to fluconazole efflux in fluconazole-resistant Candida albicans clinical isolates. Antimicrob. Agents Chemother. 52 11 (2008) 3851-3862
    • (2008) Antimicrob. Agents Chemother. , vol.52 , Issue.11 , pp. 3851-3862
    • Holmes, A.R.1    Lin, Y.H.2    Niimi, K.3    Lamping, E.4    Keniya, M.5
  • 42
    • 33748672708 scopus 로고    scopus 로고
    • Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2
    • Holmes A.R., Tsao S., Ong S.W., Lamping E., Niimi K., et al. Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2. Mol. Microbiol. 62 1 (2006) 170-186
    • (2006) Mol. Microbiol. , vol.62 , Issue.1 , pp. 170-186
    • Holmes, A.R.1    Tsao, S.2    Ong, S.W.3    Lamping, E.4    Niimi, K.5
  • 44
    • 33750329972 scopus 로고    scopus 로고
    • Reconstructing the early evolution of Fungi using a six-gene phylogeny
    • James T.Y., Kauff F., Schoch C.L., Matheny P.B., Hofstetter V., et al. Reconstructing the early evolution of Fungi using a six-gene phylogeny. Nature 443 7113 (2006) 818-822
    • (2006) Nature , vol.443 , Issue.7113 , pp. 818-822
    • James, T.Y.1    Kauff, F.2    Schoch, C.L.3    Matheny, P.B.4    Hofstetter, V.5
  • 45
    • 0037353424 scopus 로고    scopus 로고
    • The ATP-binding cassette transporters: structure, function, and gene family comparison between rice and Arabidopsis
    • Jasinski M., Ducos E., Martinoia E., and Boutry M. The ATP-binding cassette transporters: structure, function, and gene family comparison between rice and Arabidopsis. Plant Physiol. 131 3 (2003) 1169-1177
    • (2003) Plant Physiol. , vol.131 , Issue.3 , pp. 1169-1177
    • Jasinski, M.1    Ducos, E.2    Martinoia, E.3    Boutry, M.4
  • 46
    • 0141868865 scopus 로고    scopus 로고
    • Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump
    • Jha S., Karnani N., Lynn A.M., and Prasad R. Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump. Biochem. Biophys. Res. Commun. 310 3 (2003) 869-875
    • (2003) Biochem. Biophys. Res. Commun. , vol.310 , Issue.3 , pp. 869-875
    • Jha, S.1    Karnani, N.2    Lynn, A.M.3    Prasad, R.4
  • 47
    • 0042318833 scopus 로고    scopus 로고
    • Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis
    • Jha S., Karnani N., Dhar S.K., Mukhopadhayay K., Shukla S., et al. Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. Biochemistry 42 36 (2003) 10822-10832
    • (2003) Biochemistry , vol.42 , Issue.36 , pp. 10822-10832
    • Jha, S.1    Karnani, N.2    Dhar, S.K.3    Mukhopadhayay, K.4    Shukla, S.5
  • 48
    • 1842610700 scopus 로고    scopus 로고
    • The ABC transporter structure and mechanism: perspectives on recent research
    • Jones P.M., and George A.M. The ABC transporter structure and mechanism: perspectives on recent research. Cell. Mol. Life Sci. 61 6 (2004) 682-699
    • (2004) Cell. Mol. Life Sci. , vol.61 , Issue.6 , pp. 682-699
    • Jones, P.M.1    George, A.M.2
  • 49
    • 70349335633 scopus 로고    scopus 로고
    • ABC transporters: a riddle wrapped in a mystery inside an enigma
    • Jones P.M., O'Mara M.L., and George A.M. ABC transporters: a riddle wrapped in a mystery inside an enigma. Trends Biochem. Sci. 34 10 (2009) 520-531
    • (2009) Trends Biochem. Sci. , vol.34 , Issue.10 , pp. 520-531
    • Jones, P.M.1    O'Mara, M.L.2    George, A.M.3
  • 50
    • 39349086422 scopus 로고    scopus 로고
    • Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact
    • Kanafani Z.A., and Perfect J.R. Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact. Clin. Infect. Dis. 46 1 (2008) 120-128
    • (2008) Clin. Infect. Dis. , vol.46 , Issue.1 , pp. 120-128
    • Kanafani, Z.A.1    Perfect, J.R.2
  • 51
    • 0035120054 scopus 로고    scopus 로고
    • Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei
    • Katiyar S.K., and Edlind T.D. Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei. Med. Mycol. 39 1 (2001) 109-116
    • (2001) Med. Mycol. , vol.39 , Issue.1 , pp. 109-116
    • Katiyar, S.K.1    Edlind, T.D.2
  • 52
    • 0031796062 scopus 로고    scopus 로고
    • In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network
    • Kolaczkowski M., Kolaczowska A., Luczynski J., Witek S., and Goffeau A. In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network. Microb. Drug Resist. 4 3 (1998) 143-158
    • (1998) Microb. Drug Resist. , vol.4 , Issue.3 , pp. 143-158
    • Kolaczkowski, M.1    Kolaczowska, A.2    Luczynski, J.3    Witek, S.4    Goffeau, A.5
  • 53
    • 0037197022 scopus 로고    scopus 로고
    • Antifungal drug resistance of pathogenic fungi
    • Kontoyiannis D.P., and Lewis R.E. Antifungal drug resistance of pathogenic fungi. Lancet 359 9312 (2002) 1135-1144
    • (2002) Lancet , vol.359 , Issue.9312 , pp. 1135-1144
    • Kontoyiannis, D.P.1    Lewis, R.E.2
  • 56
    • 20144389423 scopus 로고    scopus 로고
    • Zygomycosis in a tertiary-care cancer center in the era of Aspergillus-active antifungal therapy: a case-control observational study of 27 recent cases
    • Kontoyiannis D.P., Lionakis M.S., Lewis R.E., Chamilos G., Healy M., et al. Zygomycosis in a tertiary-care cancer center in the era of Aspergillus-active antifungal therapy: a case-control observational study of 27 recent cases. J. Infect. Dis. 191 8 (2005) 1350-1360
    • (2005) J. Infect. Dis. , vol.191 , Issue.8 , pp. 1350-1360
    • Kontoyiannis, D.P.1    Lionakis, M.S.2    Lewis, R.E.3    Chamilos, G.4    Healy, M.5
  • 57
    • 0030035694 scopus 로고    scopus 로고
    • An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones
    • Kralli A., and Yamamoto K.R. An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones. J. Biol. Chem. 271 29 (1996) 17152-17156
    • (1996) J. Biol. Chem. , vol.271 , Issue.29 , pp. 17152-17156
    • Kralli, A.1    Yamamoto, K.R.2
  • 58
    • 0036151240 scopus 로고    scopus 로고
    • Comparison of biofilms formed by Candida albicans and Candida parapsilosis on bioprosthetic surfaces
    • Kuhn D.M., Chandra J., Mukherjee P.K., and Ghannoum M.A. Comparison of biofilms formed by Candida albicans and Candida parapsilosis on bioprosthetic surfaces. Infect. Immun. 70 2 (2002) 878-888
    • (2002) Infect. Immun. , vol.70 , Issue.2 , pp. 878-888
    • Kuhn, D.M.1    Chandra, J.2    Mukherjee, P.K.3    Ghannoum, M.A.4
  • 59
    • 43049141529 scopus 로고    scopus 로고
    • Current challenges in the management of invasive fungal infections
    • Lai C.C., Tan C.K., Huang Y.T., Shao P.L., and Hsueh P.R. Current challenges in the management of invasive fungal infections. J. Infect. Chemother. 14 2 (2008) 77-85
    • (2008) J. Infect. Chemother. , vol.14 , Issue.2 , pp. 77-85
    • Lai, C.C.1    Tan, C.K.2    Huang, Y.T.3    Shao, P.L.4    Hsueh, P.R.5
  • 60
    • 59749098790 scopus 로고    scopus 로고
    • Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei
    • Lamping E., Ranchod A., Nakamura K., Tyndall J.D., Niimi K., et al. Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei. Antimicrob. Agents Chemother. 53 2 (2009) 354-369
    • (2009) Antimicrob. Agents Chemother. , vol.53 , Issue.2 , pp. 354-369
    • Lamping, E.1    Ranchod, A.2    Nakamura, K.3    Tyndall, J.D.4    Niimi, K.5
  • 61
    • 34447579240 scopus 로고    scopus 로고
    • Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae
    • Lamping E., Monk B.C., Niimi K., Holmes A.R., Tsao S., et al. Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. Eukaryot. Cell 6 7 (2007) 1150-1165
    • (2007) Eukaryot. Cell , vol.6 , Issue.7 , pp. 1150-1165
    • Lamping, E.1    Monk, B.C.2    Niimi, K.3    Holmes, A.R.4    Tsao, S.5
  • 62
    • 7244238074 scopus 로고    scopus 로고
    • ATP-binding cassette (ABC) transporters mediate nonvesicular, raft-modulated sterol movement from the plasma membrane to the endoplasmic reticulum
    • Li Y., and Prinz W.A. ATP-binding cassette (ABC) transporters mediate nonvesicular, raft-modulated sterol movement from the plasma membrane to the endoplasmic reticulum. J. Biol. Chem. 279 43 (2004) 45226-45234
    • (2004) J. Biol. Chem. , vol.279 , Issue.43 , pp. 45226-45234
    • Li, Y.1    Prinz, W.A.2
  • 63
    • 33750289222 scopus 로고    scopus 로고
    • The biology of the Cryptococcus neoformans species complex
    • Lin X., and Heitman J. The biology of the Cryptococcus neoformans species complex. Annu. Rev. Microbiol. 60 (2006) 69-105
    • (2006) Annu. Rev. Microbiol. , vol.60 , pp. 69-105
    • Lin, X.1    Heitman, J.2
  • 64
    • 0031943304 scopus 로고    scopus 로고
    • The Escherichia coli ATP-binding cassette (ABC) proteins
    • Linton K.J., and Higgins C.F. The Escherichia coli ATP-binding cassette (ABC) proteins. Mol. Microbiol. 28 1 (1998) 5-13
    • (1998) Mol. Microbiol. , vol.28 , Issue.1 , pp. 5-13
    • Linton, K.J.1    Higgins, C.F.2
  • 65
    • 0037052565 scopus 로고    scopus 로고
    • The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism
    • Locher K.P., Lee A.T., and Rees D.C. The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism. Science 296 5570 (2002) 1091-1098
    • (2002) Science , vol.296 , Issue.5570 , pp. 1091-1098
    • Locher, K.P.1    Lee, A.T.2    Rees, D.C.3
  • 66
    • 20044380139 scopus 로고    scopus 로고
    • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans
    • Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., et al. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science 307 5713 (2005) 1321-1324
    • (2005) Science , vol.307 , Issue.5713 , pp. 1321-1324
    • Loftus, B.J.1    Fung, E.2    Roncaglia, P.3    Rowley, D.4    Amedeo, P.5
  • 67
    • 0035022252 scopus 로고    scopus 로고
    • Mechanisms of fluconazole resistance in Candida albicans isolates from Japanese AIDS patients
    • Maebashi K., Niimi M., Kudoh M., Fischer F.J., Makimura K., et al. Mechanisms of fluconazole resistance in Candida albicans isolates from Japanese AIDS patients. J. Antimicrob. Chemother. 47 5 (2001) 527-536
    • (2001) J. Antimicrob. Chemother. , vol.47 , Issue.5 , pp. 527-536
    • Maebashi, K.1    Niimi, M.2    Kudoh, M.3    Fischer, F.J.4    Makimura, K.5
  • 68
    • 0034962824 scopus 로고    scopus 로고
    • Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species
    • Mellado E., Diaz-Guerra T.M., Cuenca-Estrella M., and Rodriguez-Tudela J.L. Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species. J. Clin. Microbiol. 39 7 (2001) 2431-2438
    • (2001) J. Clin. Microbiol. , vol.39 , Issue.7 , pp. 2431-2438
    • Mellado, E.1    Diaz-Guerra, T.M.2    Cuenca-Estrella, M.3    Rodriguez-Tudela, J.L.4
  • 69
    • 19544388244 scopus 로고    scopus 로고
    • Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility
    • Mellado E., Garcia-Effron G., Buitrago M.J., Alcazar-Fuoli L., Cuenca-Estrella M., et al. Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility. Antimicrob. Agents Chemother. 49 6 (2005) 2536-2538
    • (2005) Antimicrob. Agents Chemother. , vol.49 , Issue.6 , pp. 2536-2538
    • Mellado, E.1    Garcia-Effron, G.2    Buitrago, M.J.3    Alcazar-Fuoli, L.4    Cuenca-Estrella, M.5
  • 70
    • 0031807604 scopus 로고    scopus 로고
    • Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata
    • Miyazaki H., Miyazaki Y., Geber A., Parkinson T., Hitchcock C., et al. Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata. Antimicrob. Agents Chemother. 42 7 (1998) 1695-1701
    • (1998) Antimicrob. Agents Chemother. , vol.42 , Issue.7 , pp. 1695-1701
    • Miyazaki, H.1    Miyazaki, Y.2    Geber, A.3    Parkinson, T.4    Hitchcock, C.5
  • 71
    • 47849102650 scopus 로고    scopus 로고
    • Outwitting multidrug resistance to antifungals
    • Monk B.C., and Goffeau A. Outwitting multidrug resistance to antifungals. Science 321 5887 (2008) 367-369
    • (2008) Science , vol.321 , Issue.5887 , pp. 367-369
    • Monk, B.C.1    Goffeau, A.2
  • 72
    • 0034677201 scopus 로고    scopus 로고
    • A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE
    • Muth T.R., and Schuldiner S. A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE. EMBO J. 19 2 (2000) 234-240
    • (2000) EMBO J. , vol.19 , Issue.2 , pp. 234-240
    • Muth, T.R.1    Schuldiner, S.2
  • 73
    • 0027385382 scopus 로고
    • Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions
    • Nakamura T., Liu Y., Hirata D., Namba H., Harada S., et al. Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions. EMBO J. 12 11 (1993) 4063-4071
    • (1993) EMBO J. , vol.12 , Issue.11 , pp. 4063-4071
    • Nakamura, T.1    Liu, Y.2    Hirata, D.3    Namba, H.4    Harada, S.5
  • 74
    • 36448942928 scopus 로고    scopus 로고
    • The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum
    • Nakayama H., Tanabe K., Bard M., Hodgson W., Wu S., et al. The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum. J. Antimicrob. Chemother. 60 6 (2007) 1264-1272
    • (2007) J. Antimicrob. Chemother. , vol.60 , Issue.6 , pp. 1264-1272
    • Nakayama, H.1    Tanabe, K.2    Bard, M.3    Hodgson, W.4    Wu, S.5
  • 75
    • 0037659190 scopus 로고    scopus 로고
    • Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole
    • Nascimento A.M., Goldman G.H., Park S., Marras S.A., Delmas G., et al. Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole. Antimicrob. Agents Chemother. 47 5 (2003) 1719-1726
    • (2003) Antimicrob. Agents Chemother. , vol.47 , Issue.5 , pp. 1719-1726
    • Nascimento, A.M.1    Goldman, G.H.2    Park, S.3    Marras, S.A.4    Delmas, G.5
  • 76
    • 28644434509 scopus 로고    scopus 로고
    • Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
    • Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 438 7071 (2005) 1151-1156
    • (2005) Nature , vol.438 , Issue.7071 , pp. 1151-1156
    • Nierman, W.C.1    Pain, A.2    Anderson, M.J.3    Wortman, J.R.4    Kim, H.S.5
  • 77
    • 0004246866 scopus 로고
    • Leicester University Press, Leicester 382 p
    • Odds F.C. Candida and Candidosis (1979), Leicester University Press, Leicester 382 p
    • (1979) Candida and Candidosis
    • Odds, F.C.1
  • 78
    • 0038341642 scopus 로고    scopus 로고
    • Antifungal agents: mechanisms of action
    • Odds F.C., Brown A.J., and Gow N.A. Antifungal agents: mechanisms of action. Trends Microbiol. 11 6 (2003) 272-279
    • (2003) Trends Microbiol. , vol.11 , Issue.6 , pp. 272-279
    • Odds, F.C.1    Brown, A.J.2    Gow, N.A.3
  • 79
    • 41949128129 scopus 로고    scopus 로고
    • New and emerging treatments for fungal infections
    • Pasqualotto A.C., and Denning D.W. New and emerging treatments for fungal infections. J. Antimicrob. Chemother. 61 Suppl. 1 (2008) i19-i30
    • (2008) J. Antimicrob. Chemother. , vol.61 , Issue.SUPPL. 1
    • Pasqualotto, A.C.1    Denning, D.W.2
  • 80
    • 0034812585 scopus 로고    scopus 로고
    • Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients
    • Perea S., Lopez-Ribot J.L., Kirkpatrick W.R., McAtee R.K., Santillan R.A., et al. Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients. Antimicrob. Agents Chemother. 45 10 (2001) 2676-2684
    • (2001) Antimicrob. Agents Chemother. , vol.45 , Issue.10 , pp. 2676-2684
    • Perea, S.1    Lopez-Ribot, J.L.2    Kirkpatrick, W.R.3    McAtee, R.K.4    Santillan, R.A.5
  • 81
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of invasive candidiasis: a persistent public health problem
    • Pfaller M.A., and Diekema D.J. Epidemiology of invasive candidiasis: a persistent public health problem. Clin. Microbiol. Rev. 20 1 (2007) 133-163
    • (2007) Clin. Microbiol. Rev. , vol.20 , Issue.1 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 82
  • 83
    • 38949166771 scopus 로고    scopus 로고
    • Candida krusei, a multidrug-resistant opportunistic fungal pathogen: geographic and temporal trends from the ARTEMIS DISK Antifungal Surveillance Program, 2001 to 2005
    • Pfaller M.A., Diekema D.J., Gibbs D.L., Newell V.A., Nagy E., et al. Candida krusei, a multidrug-resistant opportunistic fungal pathogen: geographic and temporal trends from the ARTEMIS DISK Antifungal Surveillance Program, 2001 to 2005. J. Clin. Microbiol. 46 2 (2008) : 515-521
    • (2008) J. Clin. Microbiol. , vol.46 , Issue.2
    • Pfaller, M.A.1    Diekema, D.J.2    Gibbs, D.L.3    Newell, V.A.4    Nagy, E.5
  • 84
    • 0037238468 scopus 로고    scopus 로고
    • Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole
    • Posteraro B., Sanguinetti M., Sanglard D., La Sorda M., Boccia S., et al. Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole. Mol. Microbiol. 47 2 (2003) 357-371
    • (2003) Mol. Microbiol. , vol.47 , Issue.2 , pp. 357-371
    • Posteraro, B.1    Sanguinetti, M.2    Sanglard, D.3    La Sorda, M.4    Boccia, S.5
  • 86
    • 0025931033 scopus 로고
    • The product of the YCR105 gene located on the chromosome III from Saccharomyces cerevisiae presents homologies to ATP-dependent permeases
    • Purnelle B., Skala J., and Goffeau A. The product of the YCR105 gene located on the chromosome III from Saccharomyces cerevisiae presents homologies to ATP-dependent permeases. Yeast 7 8 (1991) 867-872
    • (1991) Yeast , vol.7 , Issue.8 , pp. 867-872
    • Purnelle, B.1    Skala, J.2    Goffeau, A.3
  • 87
    • 17844379452 scopus 로고    scopus 로고
    • Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding
    • Rai V., Shukla S., Jha S., Komath S.S., and Prasad R. Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding. Biochemistry 44 17 (2005) 6650-6661
    • (2005) Biochemistry , vol.44 , Issue.17 , pp. 6650-6661
    • Rai, V.1    Shukla, S.2    Jha, S.3    Komath, S.S.4    Prasad, R.5
  • 89
    • 0037378017 scopus 로고    scopus 로고
    • Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates
    • Rogers P.D., and Barker K.S. Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates. Antimicrob. Agents Chemother. 47 4 (2003) 1220-1227
    • (2003) Antimicrob. Agents Chemother. , vol.47 , Issue.4 , pp. 1220-1227
    • Rogers, P.D.1    Barker, K.S.2
  • 90
    • 3242885293 scopus 로고    scopus 로고
    • The predictprotein server
    • Rost B., Yachdav G., and Liu J. The predictprotein server. Nucleic Acids Res. 32 Web Server issue (2004) W321-W326
    • (2004) Nucleic Acids Res. , vol.32 , Issue.Web Server issue
    • Rost, B.1    Yachdav, G.2    Liu, J.3
  • 91
    • 0033801252 scopus 로고    scopus 로고
    • Practice guidelines for the management of cryptococcal disease. Infectious diseases society of America
    • Saag M.S., Graybill R.J., Larsen R.A., Pappas P.G., Perfect J.R., et al. Practice guidelines for the management of cryptococcal disease. Infectious diseases society of America. Clin. Infect. Dis. 30 4 (2000) 710-718
    • (2000) Clin. Infect. Dis. , vol.30 , Issue.4 , pp. 710-718
    • Saag, M.S.1    Graybill, R.J.2    Larsen, R.A.3    Pappas, P.G.4    Perfect, J.R.5
  • 92
    • 24044514014 scopus 로고    scopus 로고
    • Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux
    • Saini P., Prasad T., Gaur N.A., Shukla S., Jha S., et al. Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux. J. Antimicrob. Chemother. 56 1 (2005) 77-86
    • (2005) J. Antimicrob. Chemother. , vol.56 , Issue.1 , pp. 77-86
    • Saini, P.1    Prasad, T.2    Gaur, N.A.3    Shukla, S.4    Jha, S.5
  • 93
    • 0002896893 scopus 로고    scopus 로고
    • Current understanding of the modes of action of and resistance mechanisms to conventional and emerging antifungal agents for treatment of Candida infections
    • Calderone R.A. (Ed), ASM Press, Washington, DC
    • Sanglard D., and Bille J. Current understanding of the modes of action of and resistance mechanisms to conventional and emerging antifungal agents for treatment of Candida infections. In: Calderone R.A. (Ed). Candida and Candidiasis (2002), ASM Press, Washington, DC 349-383
    • (2002) Candida and Candidiasis , pp. 349-383
    • Sanglard, D.1    Bille, J.2
  • 94
    • 0035080323 scopus 로고    scopus 로고
    • Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata
    • Sanglard D., Ischer F., and Bille J. Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata. Antimicrob. Agents Chemother. 45 4 (2001) 1174-1183
    • (2001) Antimicrob. Agents Chemother. , vol.45 , Issue.4 , pp. 1174-1183
    • Sanglard, D.1    Ischer, F.2    Bille, J.3
  • 95
    • 0032734512 scopus 로고    scopus 로고
    • The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents
    • Sanglard D., Ischer F., Calabrese D., Majcherczyk P.A., and Bille J. The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents. Antimicrob. Agents Chemother. 43 11 (1999) 2753-2765
    • (1999) Antimicrob. Agents Chemother. , vol.43 , Issue.11 , pp. 2753-2765
    • Sanglard, D.1    Ischer, F.2    Calabrese, D.3    Majcherczyk, P.A.4    Bille, J.5
  • 96
    • 0028793725 scopus 로고
    • Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
    • Sanglard D., Kuchler K., Ischer F., Pagani J.L., Monod M., et al. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters. Antimicrob. Agents Chemother. 39 11 (1995) 2378-2386
    • (1995) Antimicrob. Agents Chemother. , vol.39 , Issue.11 , pp. 2378-2386
    • Sanglard, D.1    Kuchler, K.2    Ischer, F.3    Pagani, J.L.4    Monod, M.5
  • 97
    • 31844440045 scopus 로고    scopus 로고
    • Role of AFR1, an ABC transporter-encoding gene, in the in vivo response to fluconazole and virulence of Cryptococcus neoformans
    • Sanguinetti M., Posteraro B., La Sorda M., Torelli R., Fiori B., et al. Role of AFR1, an ABC transporter-encoding gene, in the in vivo response to fluconazole and virulence of Cryptococcus neoformans. Infect. Immun. 74 2 (2006) 1352-1359
    • (2006) Infect. Immun. , vol.74 , Issue.2 , pp. 1352-1359
    • Sanguinetti, M.1    Posteraro, B.2    La Sorda, M.3    Torelli, R.4    Fiori, B.5
  • 98
    • 20444470082 scopus 로고    scopus 로고
    • Emergence of fluconazole resistance in a Candida parapsilosis strain that caused infections in a neonatal intensive care unit
    • Sarvikivi E., Lyytikainen O., Soll D.R., Pujol C., Pfaller M.A., et al. Emergence of fluconazole resistance in a Candida parapsilosis strain that caused infections in a neonatal intensive care unit. J. Clin. Microbiol. 43 6 (2005) 2729-2735
    • (2005) J. Clin. Microbiol. , vol.43 , Issue.6 , pp. 2729-2735
    • Sarvikivi, E.1    Lyytikainen, O.2    Soll, D.R.3    Pujol, C.4    Pfaller, M.A.5
  • 99
    • 58049197842 scopus 로고    scopus 로고
    • Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport
    • Sauna Z.E., Bohn S.S., Rutledge R., Dougherty M.P., Cronin S., et al. Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transport. J. Biol. Chem. 283 50 (2008) 35010-35022
    • (2008) J. Biol. Chem. , vol.283 , Issue.50 , pp. 35010-35022
    • Sauna, Z.E.1    Bohn, S.S.2    Rutledge, R.3    Dougherty, M.P.4    Cronin, S.5
  • 100
    • 0032951188 scopus 로고    scopus 로고
    • Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters
    • Saurin W., Hofnung M., and Dassa E. Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters. J. Mol. Evol. 48 1 (1999) 22-41
    • (1999) J. Mol. Evol. , vol.48 , Issue.1 , pp. 22-41
    • Saurin, W.1    Hofnung, M.2    Dassa, E.3
  • 101
    • 0031810816 scopus 로고    scopus 로고
    • ATP-binding-cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains
    • Schneider E., and Hunke S. ATP-binding-cassette (ABC) transport systems: functional and structural aspects of the ATP-hydrolyzing subunits/domains. FEMS Microbiol. Rev. 22 1 (1998) 1-20
    • (1998) FEMS Microbiol. Rev. , vol.22 , Issue.1 , pp. 1-20
    • Schneider, E.1    Hunke, S.2
  • 102
    • 0037342112 scopus 로고    scopus 로고
    • Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR
    • Schumacher M.A., and Brennan R.G. Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR. Res. Microbiol. 154 2 (2003) 69-77
    • (2003) Res. Microbiol. , vol.154 , Issue.2 , pp. 69-77
    • Schumacher, M.A.1    Brennan, R.G.2
  • 103
    • 64649088477 scopus 로고    scopus 로고
    • Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi
    • Shahi P., and Moye-Rowley W.S. Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi. Biochim. Biophys. Acta 1794 5 (2009) 852-859
    • (2009) Biochim. Biophys. Acta , vol.1794 , Issue.5 , pp. 852-859
    • Shahi, P.1    Moye-Rowley, W.S.2
  • 104
    • 35748935537 scopus 로고    scopus 로고
    • Recent advances and challenges in the treatment of invasive fungal infections
    • Shao P.L., Huang L.M., and Hsueh P.R. Recent advances and challenges in the treatment of invasive fungal infections. Int. J. Antimicrob. Agents 30 6 (2007) 487-495
    • (2007) Int. J. Antimicrob. Agents , vol.30 , Issue.6 , pp. 487-495
    • Shao, P.L.1    Huang, L.M.2    Hsueh, P.R.3
  • 105
    • 0347694571 scopus 로고    scopus 로고
    • Functional characterization of Candida albicans ABC transporter Cdr1p
    • Shukla S., Saini P., Smriti, Jha S., Ambudkar S.V., et al. Functional characterization of Candida albicans ABC transporter Cdr1p. Eukaryot. Cell 2 6 (2003) 1361-1375
    • (2003) Eukaryot. Cell , vol.2 , Issue.6 , pp. 1361-1375
    • Shukla, S.1    Saini, P.2    Smriti3    Jha, S.4    Ambudkar, S.V.5
  • 106
    • 34249701218 scopus 로고    scopus 로고
    • Fungal infections in solid organ transplantation
    • Silveira F.P., and Husain S. Fungal infections in solid organ transplantation. Med. Mycol. 45 4 (2007) 305-320
    • (2007) Med. Mycol. , vol.45 , Issue.4 , pp. 305-320
    • Silveira, F.P.1    Husain, S.2
  • 107
    • 12944291020 scopus 로고    scopus 로고
    • Aspergillus infections in transplant recipients
    • Singh N., and Paterson D.L. Aspergillus infections in transplant recipients. Clin. Microbiol. Rev. 18 1 (2005) 44-69
    • (2005) Clin. Microbiol. Rev. , vol.18 , Issue.1 , pp. 44-69
    • Singh, N.1    Paterson, D.L.2
  • 108
    • 34249895255 scopus 로고    scopus 로고
    • Vulvovaginal candidosis
    • Sobel J.D. Vulvovaginal candidosis. Lancet 369 9577 (2007) 1961-1971
    • (2007) Lancet , vol.369 , Issue.9577 , pp. 1961-1971
    • Sobel, J.D.1
  • 110
    • 0032322715 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae ABC proteins and their relevance to human health and disease
    • Taglicht D., and Michaelis S. Saccharomyces cerevisiae ABC proteins and their relevance to human health and disease. Methods Enzymol. 292 (1998) 130-162
    • (1998) Methods Enzymol. , vol.292 , pp. 130-162
    • Taglicht, D.1    Michaelis, S.2
  • 111
    • 0034805822 scopus 로고    scopus 로고
    • Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjogren's syndrome
    • Tanaka A.R., Ikeda Y., Abe-Dohmae S., Arakawa R., Sadanami K., et al. Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjogren's syndrome. Biochem. Biophys. Res. Commun. 283 5 (2001) 1019-1025
    • (2001) Biochem. Biophys. Res. Commun. , vol.283 , Issue.5 , pp. 1019-1025
    • Tanaka, A.R.1    Ikeda, Y.2    Abe-Dohmae, S.3    Arakawa, R.4    Sadanami, K.5
  • 112
    • 0030781143 scopus 로고    scopus 로고
    • Cloning and characterization of CneMDR1: a Cryptococcus neoformans gene encoding a protein related to multidrug resistance proteins
    • Thornewell S.J., Peery R.B., and Skatrud P.L. Cloning and characterization of CneMDR1: a Cryptococcus neoformans gene encoding a protein related to multidrug resistance proteins. Gene 201 1-2 (1997) 21-29
    • (1997) Gene , vol.201 , Issue.1-2 , pp. 21-29
    • Thornewell, S.J.1    Peery, R.B.2    Skatrud, P.L.3
  • 113
    • 65749096905 scopus 로고    scopus 로고
    • Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance
    • Tsao S., Rahkhoodaee F., and Raymond M. Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance. Antimicrob. Agents Chemother. 53 4 (2009) 1344-1352
    • (2009) Antimicrob. Agents Chemother. , vol.53 , Issue.4 , pp. 1344-1352
    • Tsao, S.1    Rahkhoodaee, F.2    Raymond, M.3
  • 114
    • 31844440738 scopus 로고    scopus 로고
    • Membrane topology of human ABC proteins
    • Tusnady G.E., Sarkadi B., Simon I., and Varadi A. Membrane topology of human ABC proteins. FEBS Lett. 580 4 (2006) 1017-1022
    • (2006) FEBS Lett. , vol.580 , Issue.4 , pp. 1017-1022
    • Tusnady, G.E.1    Sarkadi, B.2    Simon, I.3    Varadi, A.4
  • 115
    • 17844373518 scopus 로고    scopus 로고
    • Mutational analysis of the yeast multidrug resistance ABC transporter Pdr5p with altered drug specificity
    • Tutulan-Cunita A.C., Mikoshi M., Mizunuma M., Hirata D., and Miyakawa T. Mutational analysis of the yeast multidrug resistance ABC transporter Pdr5p with altered drug specificity. Genes Cells 10 5 (2005) 409-420
    • (2005) Genes Cells , vol.10 , Issue.5 , pp. 409-420
    • Tutulan-Cunita, A.C.1    Mikoshi, M.2    Mizunuma, M.3    Hirata, D.4    Miyakawa, T.5
  • 116
    • 0036835919 scopus 로고    scopus 로고
    • The plant PDR family of ABC transporters
    • van den Brule S., and Smart C.C. The plant PDR family of ABC transporters. Planta 216 1 (2002) 95-106
    • (2002) Planta , vol.216 , Issue.1 , pp. 95-106
    • van den Brule, S.1    Smart, C.C.2
  • 117
    • 41649116602 scopus 로고    scopus 로고
    • Plant ABC proteins - a unified nomenclature and updated inventory
    • Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., et al. Plant ABC proteins - a unified nomenclature and updated inventory. Trends Plant Sci. 13 4 (2008) 151-159
    • (2008) Trends Plant Sci. , vol.13 , Issue.4 , pp. 151-159
    • Verrier, P.J.1    Bird, D.2    Burla, B.3    Dassa, E.4    Forestier, C.5
  • 118
    • 0029108665 scopus 로고
    • Membrane protein assembly: rules of the game
    • von Heijne G. Membrane protein assembly: rules of the game. Bioessays 17 1 (1995) 25-30
    • (1995) Bioessays , vol.17 , Issue.1 , pp. 25-30
    • von Heijne, G.1
  • 119
    • 12844283318 scopus 로고    scopus 로고
    • Phosphorylation of Candida glabrata ATP-binding cassette transporter Cdr1p regulates drug efflux activity and ATPase stability
    • Wada S., Tanabe K., Yamazaki A., Niimi M., Uehara Y., et al. Phosphorylation of Candida glabrata ATP-binding cassette transporter Cdr1p regulates drug efflux activity and ATPase stability. J. Biol. Chem. 280 1 (2005) 94-103
    • (2005) J. Biol. Chem. , vol.280 , Issue.1 , pp. 94-103
    • Wada, S.1    Tanabe, K.2    Yamazaki, A.3    Niimi, M.4    Uehara, Y.5
  • 120
    • 0034693064 scopus 로고    scopus 로고
    • Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1
    • Wang N., Silver D.L., Costet P., and Tall A.R. Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1. J. Biol. Chem. 275 42 (2000) 33053-33058
    • (2000) J. Biol. Chem. , vol.275 , Issue.42 , pp. 33053-33058
    • Wang, N.1    Silver, D.L.2    Costet, P.3    Tall, A.R.4
  • 121
    • 0030757227 scopus 로고    scopus 로고
    • Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus
    • White T.C. Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrob. Agents Chemother. 41 7 (1997) 1482-1487
    • (1997) Antimicrob. Agents Chemother. , vol.41 , Issue.7 , pp. 1482-1487
    • White, T.C.1
  • 122
    • 0031969879 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular factors that contribute to antifungal drug resistance
    • White T.C., Marr K.A., and Bowden R.A. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin. Microbiol. Rev. 11 2 (1998) 382-402
    • (1998) Clin. Microbiol. Rev. , vol.11 , Issue.2 , pp. 382-402
    • White, T.C.1    Marr, K.A.2    Bowden, R.A.3
  • 123
    • 0032564269 scopus 로고    scopus 로고
    • The aetiology, diagnosis and management of denture stomatitis
    • Wilson J. The aetiology, diagnosis and management of denture stomatitis. Br. Dent. J. 185 8 (1998) : 380-384
    • (1998) Br. Dent. J. , vol.185 , Issue.8
    • Wilson, J.1
  • 124
    • 0028891715 scopus 로고
    • Importance of Candida species other than C. albicans as pathogens in oncology patients
    • Wingard J.R. Importance of Candida species other than C. albicans as pathogens in oncology patients. Clin. Infect. Dis. 20 1 (1995) : 115-125
    • (1995) Clin. Infect. Dis. , vol.20 , Issue.1
    • Wingard, J.R.1
  • 125
    • 3943093972 scopus 로고    scopus 로고
    • Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study
    • Wisplinghoff H., Bischoff T., Tallent S.M., Seifert H., Wenzel R.P., et al. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin. Infect. Dis. 39 3 (2004) 309-317
    • (2004) Clin. Infect. Dis. , vol.39 , Issue.3 , pp. 309-317
    • Wisplinghoff, H.1    Bischoff, T.2    Tallent, S.M.3    Seifert, H.4    Wenzel, R.P.5


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