Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis

Analytical Chemistry

Volumn 86, Issue 16, 2014, Pages 8473-8480

  Swales, John G ^a,e   Tucker, James W ^a   Strittmatter, Nicole ^d   Nilsson, Anna ^c   Cobice, Diego ^d   Clench, Malcolm R ^e   Mackay, C Logan ^d   Andren, Per E ^c   Takáts, Zoltán ^d   Webborn, Peter J H ^a,b   Goodwin, Richard J A ^a  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UPPSALA UNIVERSITY   (Sweden)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; DRUG DOSAGE; HISTOLOGY; IMAGING TECHNIQUES; MASS SPECTROMETRY; PHARMACOKINETICS; SURFACE ANALYSIS;

DESORPTION ELECTROSPRAY IONIZATION MASS SPECTROMETRIES; MASS-SPECTROMETRY IMAGING; MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY; PHARMACEUTICAL INDUSTRY; PHARMACEUTICAL RESEARCH AND DEVELOPMENT; PHARMACOKINETIC ANALYSIS; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTIONS;

TISSUE;

EID: 84906260278     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac502217r     Document Type: Article

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