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Volumn 9, Issue 15, 2004, Pages 652-658

Whatever happened to cassette-dosing pharmacokinetics?

Author keywords

cassette; Drug Discovery; drug discovery; Pharmaceutical Science; pharmacokinetics; screening; Techniques Methods

Indexed keywords

MACROGOL; METHYLCELLULOSE;

EID: 3242778456     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(04)03137-X     Document Type: Review
Times cited : (70)

References (28)
  • 1
    • 0037376928 scopus 로고    scopus 로고
    • Pharmaceutical profiling in drug discovery
    • Kerns E.H., Di L. Pharmaceutical profiling in drug discovery. Drug Discov. Today. 8:2003;316-323
    • (2003) Drug Discov. Today , vol.8 , pp. 316-323
    • Kerns, E.H.1    Di, L.2
  • 2
    • 3242743452 scopus 로고    scopus 로고
    • A comprehensive strategy for ADME screening in drug discovery
    • R.T. et al. Borchardt. American Association of Pharmaceutical Scientists Press
    • White R.E. A comprehensive strategy for ADME screening in drug discovery. Borchardt R.T.,, et al. Pharmaceutical Profiling in Drug Discovery for Lead Selection. 2004;431-450 American Association of Pharmaceutical Scientists Press
    • (2004) Pharmaceutical Profiling in Drug Discovery for Lead Selection , pp. 431-450
    • White, R.E.1
  • 3
    • 0037523454 scopus 로고    scopus 로고
    • Profiling drug-like properties in discovery research
    • Di L., Kerns E.H. Profiling drug-like properties in discovery research. Curr. Opin. Chem. Biol. 7:2003;402-408
    • (2003) Curr. Opin. Chem. Biol. , vol.7 , pp. 402-408
    • Di, L.1    Kerns, E.H.2
  • 4
    • 0034837087 scopus 로고    scopus 로고
    • High-throughput screening approaches for investigating drug metabolism and pharmacokinetics
    • Roberts S.A. High-throughput screening approaches for investigating drug metabolism and pharmacokinetics. Xenobiotica. 31:2001;557-589
    • (2001) Xenobiotica , vol.31 , pp. 557-589
    • Roberts, S.A.1
  • 5
    • 0031000066 scopus 로고    scopus 로고
    • Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput
    • Berman J., et al. Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput. J. Med. Chem. 40:1997;827-829
    • (1997) J. Med. Chem. , vol.40 , pp. 827-829
    • Berman, J.1
  • 6
    • 1842833762 scopus 로고    scopus 로고
    • Recent advances in use of LC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery
    • Ackermann B.L., et al. Recent advances in use of LC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery. Curr. Top. Med. Chem. 2:2002;53-66
    • (2002) Curr. Top. Med. Chem. , vol.2 , pp. 53-66
    • Ackermann, B.L.1
  • 7
  • 8
    • 0034955150 scopus 로고    scopus 로고
    • Pharmacokinetic theory of cassette dosing in drug discovery screening
    • White R.E., Manitpisitkul P. Pharmacokinetic theory of cassette dosing in drug discovery screening. Drug Metab. Dispos. 29:2001;957-966
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 957-966
    • White, R.E.1    Manitpisitkul, P.2
  • 9
    • 0034949807 scopus 로고    scopus 로고
    • Cassette dosing pharmacokinetics: Valuable tool or flawed science?
    • Christ D.D. Cassette dosing pharmacokinetics: valuable tool or flawed science? Drug Metab. Dispos. 29:2001;935
    • (2001) Drug Metab. Dispos , vol.29 , pp. 935
    • Christ, D.D.1
  • 10
    • 0036628568 scopus 로고    scopus 로고
    • Cassette dosing approach and quantitative structure-pharmacokinetic relationship study of antifungal N-myristoyltransferase inhibitors
    • Hasegawa K., et al. Cassette dosing approach and quantitative structure-pharmacokinetic relationship study of antifungal N- myristoyltransferase inhibitors. J. Chem. Inf. Comput. Sci. 42:2002;968-975
    • (2002) J. Chem. Inf. Comput. Sci. , vol.42 , pp. 968-975
    • Hasegawa, K.1
  • 11
    • 1542398964 scopus 로고    scopus 로고
    • Determination of rat oral bioavailability of soy-derived phytoestrogens using an automated on-column extraction procedure and electrospray tandem mass spectrometry
    • Mallis L.M., et al. Determination of rat oral bioavailability of soy-derived phytoestrogens using an automated on-column extraction procedure and electrospray tandem mass spectrometry. J. Chromatog. B. Analyt. Technol. Biomed. Life Sci. 796:2003;71-86
    • (2003) J. Chromatog. B. Analyt. Technol. Biomed. Life Sci. , vol.796 , pp. 71-86
    • Mallis, L.M.1
  • 12
    • 0033794877 scopus 로고    scopus 로고
    • Determination of brain and plasma drug concentrations by liquid chromatography/tandem mass spectrometry
    • Tamvakopoulos C.S., et al. Determination of brain and plasma drug concentrations by liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 14:2000;1729-1735
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 1729-1735
    • Tamvakopoulos, C.S.1
  • 13
    • 0842287429 scopus 로고    scopus 로고
    • Brain and plasma exposure profiling in early drug discovery using cassette administration and fast liquid chromatography-tandem mass spectrometry
    • Zhang M-Y, et al. Brain and plasma exposure profiling in early drug discovery using cassette administration and fast liquid chromatography-tandem mass spectrometry. J. Pharm. Biomed. Anal. 34:2004;359-368
    • (2004) J. Pharm. Biomed. Anal. , vol.34 , pp. 359-368
    • Zhang, M.-Y.1
  • 14
    • 0034121122 scopus 로고    scopus 로고
    • Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes
    • Choo E.F., et al. Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes. Drug Metab. Dispos. 28:2000;655-660
    • (2000) Drug Metab. Dispos. , vol.28 , pp. 655-660
    • Choo, E.F.1
  • 15
    • 0037194629 scopus 로고    scopus 로고
    • Discovery of further pyrrolidine trans-lactams and inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)
    • Macdonald S.J.F., et al. Discovery of further pyrrolidine trans-lactams and inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151). J. Med. Chem. 45:2002;3878-3890
    • (2002) J. Med. Chem. , vol.45 , pp. 3878-3890
    • MacDonald, S.J.F.1
  • 16
    • 10744225892 scopus 로고    scopus 로고
    • Pyrrolidine-5,5-trans-lactams. 5. pharmacokinetic optimization of inhibitors of hepatitis C virus NS3/4A protease
    • Andrews D.M., et al. Pyrrolidine-5,5-trans-lactams. 5. pharmacokinetic optimization of inhibitors of hepatitis C virus NS3/4A protease. Org. Lett. 5:2003;4631-4634
    • (2003) Org. Lett. , vol.5 , pp. 4631-4634
    • Andrews, D.M.1
  • 17
    • 0035149324 scopus 로고    scopus 로고
    • Development of an in vivo preclinical screen model to estimate absorption and bioavailability of xenobiotics
    • Ward K.W., et al. Development of an in vivo preclinical screen model to estimate absorption and bioavailability of xenobiotics. Drug Metab. Dispos. 29:2001;82-88
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 82-88
    • Ward, K.W.1
  • 18
    • 0037379564 scopus 로고    scopus 로고
    • Simultaneous assessment of drug interactions with low- and high-extraction opioids
    • Ibrahim A.E., et al. Simultaneous assessment of drug interactions with low- and high-extraction opioids. Anesthesiology. 98:2003;853-861
    • (2003) Anesthesiology , vol.98 , pp. 853-861
    • Ibrahim, A.E.1
  • 19
    • 1642494659 scopus 로고    scopus 로고
    • 'Cocktail' approaches and strategies in drug development: Valuable tool or flawed science?
    • Zhou H., et al. 'Cocktail' approaches and strategies in drug development: valuable tool or flawed science? J. Clin. Pharmacol. 44:2004;120-134
    • (2004) J. Clin. Pharmacol. , vol.44 , pp. 120-134
    • Zhou, H.1
  • 20
    • 0034887375 scopus 로고    scopus 로고
    • LC fluorescence method for multiple synthetic compounds to rapidly create in vivo pharmacokinetic database utilizing 'N-in-one' dosing
    • Rajanikanth M., Gupta R.C. LC fluorescence method for multiple synthetic compounds to rapidly create in vivo pharmacokinetic database utilizing 'N-in-one' dosing. J. Pharm. Biomed. Anal. 26:2001;519-530
    • (2001) J. Pharm. Biomed. Anal. , vol.26 , pp. 519-530
    • Rajanikanth, M.1    Gupta, R.C.2
  • 21
    • 0036489464 scopus 로고    scopus 로고
    • METAPRINT: A metabolic fingerprint. Application to cassette design for high-throughput ADME screening
    • Keseru G.M., Molnar L. METAPRINT: a metabolic fingerprint. Application to cassette design for high-throughput ADME screening. J. Chem. Inf. Comput. Sci. 42:2002;437-444
    • (2002) J. Chem. Inf. Comput. Sci. , vol.42 , pp. 437-444
    • Keseru, G.M.1    Molnar, L.2
  • 22
    • 0037430781 scopus 로고    scopus 로고
    • A new generic column switching system for quantitation in cassette dosing using LC/MS/MS
    • Ohkawa T., et al. A new generic column switching system for quantitation in cassette dosing using LC/MS/MS. J. Pharm. Biomed. Anal. 31:2003;1089-1099
    • (2003) J. Pharm. Biomed. Anal. , vol.31 , pp. 1089-1099
    • Ohkawa, T.1
  • 23
    • 0036218957 scopus 로고    scopus 로고
    • Rapid determination of pharmacokinetic properties of new chemical entities: In vivo approaches
    • Cox K.A., et al. Rapid determination of pharmacokinetic properties of new chemical entities: in vivo approaches. Comb. Chem. High Throughput Screen. 5:2002;29-37
    • (2002) Comb. Chem. High Throughput Screen , vol.5 , pp. 29-37
    • Cox, K.A.1
  • 24
    • 0035525502 scopus 로고    scopus 로고
    • Tailoring bioanalysis for PK studies supporting drug discovery
    • Timmerman P.M.M.B.L., et al. Tailoring bioanalysis for PK studies supporting drug discovery. Curr. Top. Med. Chem. 1:2001;443-461
    • (2001) Curr. Top. Med. Chem. , vol.1 , pp. 443-461
    • Timmerman, P.M.M.B.L.1
  • 25
    • 0033007061 scopus 로고    scopus 로고
    • Sample pooling to enhance throughput of brain penetration study
    • Atherton J.P., et al. Sample pooling to enhance throughput of brain penetration study. J. Pharm. Biomed. Anal. 20:1999;39-47
    • (1999) J. Pharm. Biomed. Anal. , vol.20 , pp. 39-47
    • Atherton, J.P.1
  • 26
    • 0035032944 scopus 로고    scopus 로고
    • High-throughput analysis in drug discovery: Application of liquid chromatography/ion-trap mass spectrometry for simultaneous cassette analysis of α-1a antagonists and their metabolites in mouse plasma
    • Cai Z., et al. High-throughput analysis in drug discovery: application of liquid chromatography/ion-trap mass spectrometry for simultaneous cassette analysis of α-1a antagonists and their metabolites in mouse plasma. Rapid Commun. Mass Spectrom. 15:2001;546-550
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , pp. 546-550
    • Cai, Z.1
  • 27
    • 0036164807 scopus 로고    scopus 로고
    • Direct cocktail analysis of drug discovery compounds in pooled plasma samples using liquid chromatography-tandem mass spectrometry
    • Hsieh Y., et al. Direct cocktail analysis of drug discovery compounds in pooled plasma samples using liquid chromatography-tandem mass spectrometry. J. Chromatog. B. Analyt. Technol. Biomed. Life Sci. 767:2002;353-362
    • (2002) J. Chromatog. B. Analyt. Technol. Biomed. Life Sci. , vol.767 , pp. 353-362
    • Hsieh, Y.1
  • 28
    • 0035100437 scopus 로고    scopus 로고
    • Cassette-accelerated rapid rat screen: A systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery
    • Korfmacher W.A., et al. Cassette-accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery. Rapid Commun. Mass Spectrom. 15:2001;335-340
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , pp. 335-340
    • Korfmacher, W.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.