Rapid determination of oral pharmacokinetics and plasma free fraction using cocktail approaches: Methods and application

Pharmaceutical Research

Volumn 15, Issue 1, 1998, Pages 93-97

  Allen, Mary C ^a   Shah, Toral S ^a   Day, Wesley W ^a  

^a PFIZER INC   (United States)

Author keywords

Cocktail dosing; HPLC APCI MS; Pharmacokinetics; Plasma free fraction; Ultrafiltration

Indexed keywords

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MIXTURE; DRUG POTENCY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; PROTEIN BINDING; RAT; TECHNIQUE; ULTRAFILTRATION;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; DRUG COMBINATIONS; MALE; PHARMACOKINETICS; RATS; RATS, SPRAGUE-DAWLEY; ULTRAFILTRATION;

EID: 0031915533     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011909022226     Document Type: Article

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