Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development

AAPS Journal

Volumn 12, Issue 1, 2010, Pages 11-26

  Solon, Eric G ^a   Schweitzer, Alain ^b   Stoeckli, Markus ^b   Prideaux, Brendan ^b  

^a QPS LLC   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

MALDI MSI; Microautoradiography; SIMS MSI; Whole body autoradiography

Indexed keywords

22 OXACALCITRIOL; CARBON 14; DEFERASIROX; DICLOFENAC; FINGOLIMOD; FLUORODEOXYGLUCOSE F 18; IODINE 125; SULFUR 35; TRITIUM; ZOLEDRONIC ACID;

AUTORADIOGRAPHY; DOSIMETRY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG SCREENING; HUMAN; IMAGE PROCESSING; ISOTOPE LABELING; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR IMAGING; NONHUMAN; PRODUCT DEVELOPMENT; RADIOACTIVITY; REVIEW; SINGLE DRUG DOSE; TISSUE DISTRIBUTION; WHOLE BODY AUTORADIOGRAPHY; ANIMAL; DRUG DEVELOPMENT; METHODOLOGY;

ANIMALS; AUTORADIOGRAPHY; DRUG DISCOVERY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROMETRY, MASS, SECONDARY ION;

EID: 77449124587     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-009-9158-4     Document Type: Review

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